CN101180119B - 通过本体聚合制备可再吸收的聚酯的方法 - Google Patents

通过本体聚合制备可再吸收的聚酯的方法 Download PDF

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Publication number
CN101180119B
CN101180119B CN2006800177058A CN200680017705A CN101180119B CN 101180119 B CN101180119 B CN 101180119B CN 2006800177058 A CN2006800177058 A CN 2006800177058A CN 200680017705 A CN200680017705 A CN 200680017705A CN 101180119 B CN101180119 B CN 101180119B
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China
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reactor
lactide
resorbent
polyester
polymerization
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Expired - Lifetime
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CN2006800177058A
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Chinese (zh)
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CN101180119A (zh
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A·范德瓦尔
A·C·莫尔
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Purac Biochem BV
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Purac Biochem BV
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/02—Apparatus characterised by being constructed of material selected for its chemically-resistant properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/24—Stationary reactors without moving elements inside
    • B01J19/248—Reactors comprising multiple separated flow channels
    • B01J19/249—Plate-type reactors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/785—Preparation processes characterised by the apparatus used
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00004—Scale aspects
    • B01J2219/00015—Scale-up
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02—Apparatus characterised by their chemically-resistant properties
    • B01J2219/0204—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
    • B01J2219/0245—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components of synthetic organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/19—Details relating to the geometry of the reactor
    • B01J2219/192—Details relating to the geometry of the reactor polygonal
    • B01J2219/1923—Details relating to the geometry of the reactor polygonal square or square-derived
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/19—Details relating to the geometry of the reactor
    • B01J2219/194—Details relating to the geometry of the reactor round
    • B01J2219/1941—Details relating to the geometry of the reactor round circular or disk-shaped
    • B01J2219/1943—Details relating to the geometry of the reactor round circular or disk-shaped cylindrical
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2451—Geometry of the reactor
    • B01J2219/2453—Plates arranged in parallel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2451—Geometry of the reactor
    • B01J2219/2454—Plates arranged concentrically
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2461—Heat exchange aspects
    • B01J2219/2467—Additional heat exchange means, e.g. electric resistance heaters, coils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2491—Other constructional details
    • B01J2219/2492—Assembling means
    • B01J2219/2493—Means for assembling plates together, e.g. sealing means, screws, bolts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2491—Other constructional details
    • B01J2219/2492—Assembling means
    • B01J2219/2493—Means for assembling plates together, e.g. sealing means, screws, bolts
    • B01J2219/2495—Means for assembling plates together, e.g. sealing means, screws, bolts the plates being assembled interchangeably or in a disposable way
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/24—Stationary reactors without moving elements inside
    • B01J2219/2401—Reactors comprising multiple separate flow channels
    • B01J2219/245—Plate-type reactors
    • B01J2219/2491—Other constructional details
    • B01J2219/2497—Size aspects, i.e. concrete sizes are being mentioned in the classified document
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Polyesters Or Polycarbonates (AREA)
CN2006800177058A 2005-04-21 2006-04-21 通过本体聚合制备可再吸收的聚酯的方法 Expired - Lifetime CN101180119B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05103243.1 2005-04-21
EP05103243 2005-04-21
PCT/EP2006/061751 WO2006111578A1 (en) 2005-04-21 2006-04-21 Process for preparing resorbable polyesters by bulk polymerization

Publications (2)

Publication Number Publication Date
CN101180119A CN101180119A (zh) 2008-05-14
CN101180119B true CN101180119B (zh) 2011-11-23

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CN2006800177058A Expired - Lifetime CN101180119B (zh) 2005-04-21 2006-04-21 通过本体聚合制备可再吸收的聚酯的方法

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Country Link
US (1) US7842261B2 (https=)
EP (1) EP1871519B1 (https=)
JP (1) JP5188955B2 (https=)
CN (1) CN101180119B (https=)
BR (1) BRPI0610024A2 (https=)
ES (1) ES2669042T3 (https=)
WO (1) WO2006111578A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3047860B1 (en) 2006-07-20 2024-08-28 OrbusNeich Medical Pte. Ltd. Bioabsorbable polymeric composition for a medical device
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
US8691321B2 (en) 2006-10-20 2014-04-08 Orbusneich Medical, Inc. Bioabsorbable polymeric composition and medical device background
EP2030679A1 (de) * 2007-09-03 2009-03-04 Uhde Inventa-Fischer GmbH Polymerisationsreaktor, Polymerisationsvorrichtung, Verfahren zur Herstellung von bioabbaubarem Polyester sowie Verwendungen
JP6084394B2 (ja) * 2012-08-09 2017-02-22 株式会社Ｔｉ 水素発生装置の反応セル構造
ES2710603T3 (es) * 2014-11-14 2019-04-26 Evonik Roehm Gmbh Procedimiento para preparar un poliéster bio-reabsorbible en forma de partículas
CA3120479C (en) * 2018-11-27 2025-05-06 Evonik Operations Gmbh METHOD FOR PREPARING A RESORBABLE POLYESTER IN THE FORM OF GRANULES OR POWDER BY BULK POLYMERIZATION
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
CN112409584A (zh) * 2020-11-26 2021-02-26 深圳安特生物科技有限公司 制备可吸收聚酯的系统及其方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3140917A (en) * 1960-01-19 1964-07-14 Borg Warner Polymerization reactor
US20040167297A1 (en) * 2003-02-24 2004-08-26 Baker Hughes Incorporated Method of preparing a polymer under predetermined temperature conditions, and apparatus therefor
US20040230026A1 (en) * 2001-07-10 2004-11-18 Kazuyuki Yamane Polyester production process and reactor apparatus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539981A (en) 1982-11-08 1985-09-10 Johnson & Johnson Products, Inc. Absorbable bone fixation device
US4550449A (en) 1982-11-08 1985-11-05 Johnson & Johnson Products Inc. Absorbable bone fixation device
JP2941332B2 (ja) * 1990-02-08 1999-08-25 日泉化学株式会社 注型重合法による樹脂板の製造法及び注型重合用セルセット
US6359106B1 (en) * 2000-03-09 2002-03-19 Hitachi, Ltd. Production process and production apparatus for polybutylene terephthalate
DE60224259T2 (de) * 2001-01-29 2008-12-11 Toyo Engineering Corp. Reaktor sowie dessen verwendung für lösungspolymerisations- und massenpolymerisationsverfahren
CA2447769C (en) 2001-06-13 2011-07-26 Energy & Environmental International, L.C. Bulk polymerization reactors and methods for polymerization
US6458916B1 (en) * 2001-08-29 2002-10-01 Hitachi, Ltd. Production process and production apparatus for polybutylene terephthalate
FI115217B (fi) * 2001-10-15 2005-03-31 Jvs Polymers Oy Biohajoava pinnoite
DE10200738A1 (de) 2002-01-11 2003-08-07 Boehringer Ingelheim Pharma Verfahren zur Herstellung von resorbierbaren Polyestern durch Massepolymerisation
NL1028832C1 (nl) 2005-04-21 2005-06-27 Purac Biochem Bv Werkwijze voor de bereiding van resorbeerbare polyesters door middel van bulkpolymerisatie.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3140917A (en) * 1960-01-19 1964-07-14 Borg Warner Polymerization reactor
US20040230026A1 (en) * 2001-07-10 2004-11-18 Kazuyuki Yamane Polyester production process and reactor apparatus
US20040167297A1 (en) * 2003-02-24 2004-08-26 Baker Hughes Incorporated Method of preparing a polymer under predetermined temperature conditions, and apparatus therefor

Also Published As

Publication number Publication date
JP2008536996A (ja) 2008-09-11
US7842261B2 (en) 2010-11-30
EP1871519A1 (en) 2008-01-02
US20060258834A1 (en) 2006-11-16
BRPI0610024A2 (pt) 2010-05-18
WO2006111578A1 (en) 2006-10-26
ES2669042T3 (es) 2018-05-23
JP5188955B2 (ja) 2013-04-24
CN101180119A (zh) 2008-05-14
EP1871519B1 (en) 2018-03-21

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