CN101166976B - 利用朊病毒特异性肽试剂的elisa试验 - Google Patents

利用朊病毒特异性肽试剂的elisa试验 Download PDF

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Publication number
CN101166976B
CN101166976B CN2006800062251A CN200680006225A CN101166976B CN 101166976 B CN101166976 B CN 101166976B CN 2006800062251 A CN2006800062251 A CN 2006800062251A CN 200680006225 A CN200680006225 A CN 200680006225A CN 101166976 B CN101166976 B CN 101166976B
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China
Prior art keywords
peptide
prion
pathogenic
kit
prion protein
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Expired - Fee Related
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Chinese (zh)
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CN101166976A (zh
Inventor
D·佩列兹
M·米切利特谢
C·胡
X·王
M·高
M·科诺利
T·霍恩
R·楚克曼
D·基恩
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Novartis Vaccines and Diagnostics Inc
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Novartis Vaccines and Diagnostics Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2006800062251A 2005-01-13 2006-01-13 利用朊病毒特异性肽试剂的elisa试验 Expired - Fee Related CN101166976B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US64431405P 2005-01-13 2005-01-13
US60/644,314 2005-01-13
US65249305P 2005-02-11 2005-02-11
US60/652,493 2005-02-11
PCT/US2006/001437 WO2006076687A2 (en) 2005-01-13 2006-01-13 Elisa assays using prion-specific peptide reagents

Publications (2)

Publication Number Publication Date
CN101166976A CN101166976A (zh) 2008-04-23
CN101166976B true CN101166976B (zh) 2013-06-12

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CN2006800062251A Expired - Fee Related CN101166976B (zh) 2005-01-13 2006-01-13 利用朊病毒特异性肽试剂的elisa试验

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Country Link
US (1) US20090130774A1 (enExample)
EP (1) EP1848831A4 (enExample)
JP (3) JP5162250B2 (enExample)
CN (1) CN101166976B (enExample)
AU (1) AU2006204705C1 (enExample)
BR (1) BRPI0606529A2 (enExample)
CA (1) CA2594840A1 (enExample)
MX (1) MX2007008497A (enExample)
NZ (2) NZ560535A (enExample)
WO (1) WO2006076687A2 (enExample)

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US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
WO2006076683A2 (en) * 2005-01-13 2006-07-20 Novartis Vaccines And Diagnostics Inc. Isolation and detection of pathogenic prions
CN101356186A (zh) 2005-09-09 2009-01-28 诺华有限公司 朊病毒-特异性拟肽试剂
JP2010523977A (ja) * 2007-04-04 2010-07-15 ノバルティス アーゲー プリオンアッセイ
CN102083450A (zh) * 2008-04-30 2011-06-01 诺华有限公司 致病性构象异构体的分析
WO2010003227A1 (en) * 2008-07-08 2010-01-14 Amorfix Life Sciences Ltd. Detection of protein aggregates
CN102725639A (zh) * 2009-11-04 2012-10-10 诺华有限公司 蛋白质聚集物与单体分离中作为结合试剂的带正电物质
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WO2012099576A1 (en) * 2011-01-18 2012-07-26 Baxter International Inc. Measurement of anti-amyloid antibodies in human blood
DE102011057019A1 (de) * 2011-12-23 2013-06-27 Forschungszentrum Jülich GmbH Standard zur Quantifizierung von pathogenen Aggregaten aus körpereigenen Proteinen
CN102879577B (zh) * 2012-11-01 2014-04-09 山东龙美生物医学科技有限公司 一种检测朊病毒的试剂盒及其制备方法
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WO2024254043A2 (en) * 2023-06-07 2024-12-12 The Regents Of The University Of California Nmda-r activating peptides in inflammation and neuronal differentiation

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Also Published As

Publication number Publication date
CA2594840A1 (en) 2006-07-20
MX2007008497A (es) 2007-09-14
AU2006204705C1 (en) 2012-07-05
EP1848831A4 (en) 2008-11-05
CN101166976A (zh) 2008-04-23
AU2006204705B2 (en) 2011-12-01
US20090130774A1 (en) 2009-05-21
JP2009115815A (ja) 2009-05-28
NZ587255A (en) 2012-03-30
AU2006204705A1 (en) 2006-07-20
JP5162250B2 (ja) 2013-03-13
EP1848831A2 (en) 2007-10-31
NZ560535A (en) 2011-01-28
WO2006076687A3 (en) 2007-12-13
WO2006076687A2 (en) 2006-07-20
HK1118336A1 (en) 2009-02-06
BRPI0606529A2 (pt) 2009-06-30
JP2008527382A (ja) 2008-07-24
JP2012181210A (ja) 2012-09-20

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