CN101126095A - 采用丙型肝炎病毒非结构蛋白进行的基因免疫 - Google Patents
采用丙型肝炎病毒非结构蛋白进行的基因免疫 Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- C07—ORGANIC CHEMISTRY
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US7315698P | 1998-01-30 | 1998-01-30 | |
US60/073,156 | 1998-01-30 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CNB998024813A Division CN100335637C (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
Publications (1)
Publication Number | Publication Date |
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CN101126095A true CN101126095A (zh) | 2008-02-20 |
Family
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Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
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CNA2007101398938A Pending CN101126095A (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
CNB998024813A Expired - Fee Related CN100335637C (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
CNA2007101384653A Pending CN101126094A (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
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Application Number | Title | Priority Date | Filing Date |
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CNB998024813A Expired - Fee Related CN100335637C (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
CNA2007101384653A Pending CN101126094A (zh) | 1998-01-30 | 1999-01-28 | 采用丙型肝炎病毒非结构蛋白进行的基因免疫 |
Country Status (9)
Country | Link |
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EP (1) | EP1056762A4 (ko) |
JP (1) | JP2002501737A (ko) |
KR (2) | KR20060057653A (ko) |
CN (3) | CN101126095A (ko) |
AU (1) | AU746258B2 (ko) |
BR (1) | BR9908540A (ko) |
CA (1) | CA2318744A1 (ko) |
IL (1) | IL137458A0 (ko) |
WO (1) | WO1999038880A1 (ko) |
Families Citing this family (6)
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US6562346B1 (en) * | 1999-10-27 | 2003-05-13 | Chiron Corporation | Activation of HCV-specific T cells |
US6986892B1 (en) | 1999-11-24 | 2006-01-17 | Chiron Corporation | Immunogenic Hepatitis C virus non-structural polypeptides |
KR100788812B1 (ko) * | 1999-11-24 | 2007-12-27 | 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 | 신규한 hcv 비구조 폴리펩티드 |
CN1582337B (zh) | 2001-10-11 | 2011-12-14 | 默沙东公司 | 丙型肝炎病毒疫苗 |
FR2855758B1 (fr) | 2003-06-05 | 2005-07-22 | Biomerieux Sa | Composition comprenant la polyproteine ns3/ns4 et le polypeptide ns5b du vhc, vecteurs d'expression incluant les sequences nucleiques correspondantes et leur utilisation en therapeutique |
CA2851336C (en) * | 2011-10-24 | 2021-01-12 | The Trustees Of The University Of Pennsylvania | Improved hcv vaccines and methods for using the same |
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DE69133402T2 (de) * | 1990-04-04 | 2004-11-11 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Protease von hepatitis-c-virus |
US5593972A (en) * | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
AU675702B2 (en) * | 1993-01-26 | 1997-02-13 | Leslie R. Coney | Compositions and methods for delivery of genetic material |
IL118364A0 (en) * | 1995-05-22 | 1996-09-12 | Bionova Corp | A hepatitis C virus-derived composition methods for the preparation thereof and assays for the detection of hepatitis C virus |
AU719929B2 (en) * | 1996-05-24 | 2000-05-18 | Grifols Worldwide Operations Limited | Multiple epitope fusion protein |
JP2002500502A (ja) * | 1996-06-11 | 2002-01-08 | メルク エンド カンパニー インコーポレーテッド | 合成c型肝炎遺伝子 |
EP1037974B1 (en) * | 1997-12-11 | 2007-10-03 | SmithKline Beecham Corporation | Hepatitis c virus ns5b truncated protein and methods thereof to identify antiviral compounds |
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1999
- 1999-01-28 JP JP2000529347A patent/JP2002501737A/ja not_active Withdrawn
- 1999-01-28 AU AU24786/99A patent/AU746258B2/en not_active Ceased
- 1999-01-28 CN CNA2007101398938A patent/CN101126095A/zh active Pending
- 1999-01-28 BR BR9908540-2A patent/BR9908540A/pt not_active Application Discontinuation
- 1999-01-28 CN CNB998024813A patent/CN100335637C/zh not_active Expired - Fee Related
- 1999-01-28 KR KR1020067008960A patent/KR20060057653A/ko not_active IP Right Cessation
- 1999-01-28 CA CA002318744A patent/CA2318744A1/en not_active Abandoned
- 1999-01-28 IL IL13745899A patent/IL137458A0/xx unknown
- 1999-01-28 WO PCT/US1999/001823 patent/WO1999038880A1/en not_active Application Discontinuation
- 1999-01-28 KR KR1020007008307A patent/KR100628411B1/ko not_active IP Right Cessation
- 1999-01-28 EP EP99904381A patent/EP1056762A4/en not_active Withdrawn
- 1999-01-28 CN CNA2007101384653A patent/CN101126094A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
KR100628411B1 (ko) | 2006-09-28 |
CN100335637C (zh) | 2007-09-05 |
EP1056762A1 (en) | 2000-12-06 |
AU746258B2 (en) | 2002-04-18 |
CA2318744A1 (en) | 1999-08-05 |
WO1999038880A1 (en) | 1999-08-05 |
CN101126094A (zh) | 2008-02-20 |
IL137458A0 (en) | 2001-07-24 |
BR9908540A (pt) | 2000-11-28 |
AU2478699A (en) | 1999-08-16 |
KR20060057653A (ko) | 2006-05-26 |
CN1289339A (zh) | 2001-03-28 |
EP1056762A4 (en) | 2003-07-23 |
KR20010086226A (ko) | 2001-09-10 |
JP2002501737A (ja) | 2002-01-22 |
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