IL137458A0 - Genetic immunization with nonstructural proteins of hepatitis c virus - Google Patents

Genetic immunization with nonstructural proteins of hepatitis c virus

Info

Publication number
IL137458A0
IL137458A0 IL13745899A IL13745899A IL137458A0 IL 137458 A0 IL137458 A0 IL 137458A0 IL 13745899 A IL13745899 A IL 13745899A IL 13745899 A IL13745899 A IL 13745899A IL 137458 A0 IL137458 A0 IL 137458A0
Authority
IL
Israel
Prior art keywords
hepatitis
virus
nonstructural proteins
genetic immunization
immunization
Prior art date
Application number
IL13745899A
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of IL137458A0 publication Critical patent/IL137458A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
IL13745899A 1998-01-30 1999-01-28 Genetic immunization with nonstructural proteins of hepatitis c virus IL137458A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7315698P 1998-01-30 1998-01-30
PCT/US1999/001823 WO1999038880A1 (en) 1998-01-30 1999-01-28 Genetic immunization with nonstructural proteins of hepatitis c virus

Publications (1)

Publication Number Publication Date
IL137458A0 true IL137458A0 (en) 2001-07-24

Family

ID=22112053

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13745899A IL137458A0 (en) 1998-01-30 1999-01-28 Genetic immunization with nonstructural proteins of hepatitis c virus

Country Status (9)

Country Link
EP (1) EP1056762A4 (en)
JP (1) JP2002501737A (en)
KR (2) KR100628411B1 (en)
CN (3) CN101126094A (en)
AU (1) AU746258B2 (en)
BR (1) BR9908540A (en)
CA (1) CA2318744A1 (en)
IL (1) IL137458A0 (en)
WO (1) WO1999038880A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2411096T3 (en) * 1999-10-27 2013-07-04 Novartis Vaccines And Diagnostics, Inc. Activation of specific T lymphocytes against HCV
CN1425027A (en) * 1999-11-24 2003-06-18 希龙公司 HCV non-structural polypeptide
US6986892B1 (en) 1999-11-24 2006-01-17 Chiron Corporation Immunogenic Hepatitis C virus non-structural polypeptides
JP4475561B2 (en) 2001-10-11 2010-06-09 メルク・シャープ・エンド・ドーム・コーポレイション Hepatitis C virus vaccine
FR2855758B1 (en) 2003-06-05 2005-07-22 Biomerieux Sa COMPOSITION COMPRISING NS3 / NS4 POLYPROTEIN AND HCV NS5B POLYPEPTIDE, EXPRESSION VECTORS INCLUDING THE CORRESPONDING NUCLEIC SEQUENCES AND THEIR USE IN THERAPEUTICS
KR101913674B1 (en) * 2011-10-24 2018-10-31 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 Improved hcv vaccines and methods for using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE270326T1 (en) * 1990-04-04 2004-07-15 Chiron Corp PROTEASE OF HEPATITIS C VIRUS
US5593972A (en) * 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
ATE302854T1 (en) * 1993-01-26 2005-09-15 Univ Pennsylvania COMPOSITIONS AND METHODS FOR ADMINISTRATION OF GENETIC MATERIAL
AU5924396A (en) * 1995-05-22 1996-12-11 Bionova Corporation Compositions and methods for the diagnosis of, and vaccinati on against, hepatitis c virus (hcv)
ATE311463T1 (en) * 1996-05-24 2005-12-15 Chiron Corp FUSION PROTEIN WITH MULTIPLE EPITOPES
JP2002500502A (en) * 1996-06-11 2002-01-08 メルク エンド カンパニー インコーポレーテッド Synthetic hepatitis C gene
US6228576B1 (en) * 1997-12-11 2001-05-08 Smithkline Beecham Corporation Hepatitis C virus NS5B truncated protein and methods thereof to identify antiviral compounds

Also Published As

Publication number Publication date
CA2318744A1 (en) 1999-08-05
CN101126094A (en) 2008-02-20
BR9908540A (en) 2000-11-28
KR20060057653A (en) 2006-05-26
AU746258B2 (en) 2002-04-18
WO1999038880A1 (en) 1999-08-05
KR20010086226A (en) 2001-09-10
KR100628411B1 (en) 2006-09-28
CN100335637C (en) 2007-09-05
EP1056762A4 (en) 2003-07-23
AU2478699A (en) 1999-08-16
EP1056762A1 (en) 2000-12-06
CN101126095A (en) 2008-02-20
CN1289339A (en) 2001-03-28
JP2002501737A (en) 2002-01-22

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