CN101116718A - Chinese traditional medicine composition for treating alopecia areata - Google Patents

Abstract

The present invention relates to a Chinese medicine combination for curing alopecia areata, which adopts more than 10 types of Chinese herbs such as radixbupleuri, radix polygoni multiflori, rhizoma anemarrhenae and Taiwan Angelica Root, etc. as the raw materials, achieving effects of private part maintenance, internal heat clear-up, nerves soothing and qi-regulating; the invention is made by combining the prior newest scientific research achievement based on the traditional Chinese medicine differentiation therapy; the invention aims to provide the Chinese medicine combination for curing alopecia areata, and is characterized in assured therapy effect, safety, convenience, side-effect free and low cost.

Description

A kind of Chinese medicine composition for the treatment of alopecia areata

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of alopecia areata, is that a kind of alopecia areata for the treatment of is the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Alopecia areata has another name called bald, the circular alopecia of circle.Be the alopecia of a kind of circumscribed patch shape, take place suddenly, tendency of recurrence is arranged through low.Normal with hair flaking, lesion scalp on the statistics, NIP, no conscious sympton are characteristics, if whole scalp and hair-care all comes off and is called alopecia totalis.The whole body hair person that all do not come off is called alopecia universalis.The prevalence of alopecia areata is about 0.1% among the crowd, and any age all can fall ill, and is common between 5～40 years old, and wherein person between twenty and fifty are many, and both sexes all can be got involved, and do not have the difference in obvious region, season.There is alopecia areata patient's pathological changes of 95% to be confined to scalp approximately, has 4%～30% alopecia areata patient to develop into alopecia universalis approximately.Alopecia areata belongs to Chinese medicine " alopecia areata " category, is commonly called as " ghost lick head ", " alopecia areata ", " deals with " in the Huangdi's Internal Classics, the description of symptoms such as " trichomadesis ", " alopecia areata,trichomadesis " is to primary disease record the earliest.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as deficiency of the liver and kindey, stagnation of liver-QI blood stasis, blood hot air wind producing, QI and blood deficiency clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of alopecia areata.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

1.0～4 parts of 1.0～4 parts of Radix Paeoniae Rubra of 1.0～4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

0.1～2 part of 1.0～4 parts of Radix Angelicae Dahuricae of 1.0～4 parts of Radix Bupleuri of Fructus Lycii

0.1～2 part of 0.1～2 part of Radix Polygalae of 0.1～2 part of Cortex Moutan of Fructus Corni.

The weight proportion of each crude drug of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

1.5～2.5 parts of 1.5～2.5 parts of Radix Paeoniae Rubra of 1.5～2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

0.5～1.5 part of 1.5～2.5 parts of Radix Angelicae Dahuricae of 1.5～2.5 parts of Radix Bupleuri of Fructus Lycii

0.5～1.5 part of 0.5～1.5 part of Radix Polygalae of 0.5～1.5 part of Cortex Moutan of Fructus Corni.

The weight proportion of each crude drug of optimum formula of the present invention is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

2 parts of 2 parts of Radix Paeoniae Rubra of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

1 part of 2 parts of Radix Angelicae Dahuricae of 2 parts of Radix Bupleuri of Fructus Lycii

1 part of 1 part of Radix Polygalae of 1 part of Cortex Moutan of Fructus Corni.

Drug action mechanism among the present invention is as follows:

Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).

Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

Radix Angelicae Dahuricae property of medicine suffering, temperature.Return lung, spleen, stomach warp.Has expelling wind and removing dampness, understand things pain-stopping, the effect of detumescence and apocenosis.Can treat headache due to common cold, supraorbital bone pain, toothache, nasal obstruction, nasal sinusitis, domination of damp pathogen chronic diarrhea, leucorrhea with red and white discharge, ulcer sores etc.(the 951st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Polygalae property of medicine suffering, hardship, tepor.GUIXIN, lung, kidney channel.Have mind tranquilizing and the heart calming, eliminate the phlegm and have one's ideas straightened out, the effect of removing toxic substances and promoting subsidence of swelling.Can treat irritability, the palpitation with fear insomnia, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain etc.(the 1436th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Polygoni Multiflori, Radix Rehmanniae Preparata and the Rhizoma Anemarrhenae; With Fructus Ligustri Lucidi, Herba Ecliptae, Radix Paeoniae Rubra, Fructus Lycii, Radix Bupleuri and Fructus Corni is ministerial drug; With the Radix Angelicae Dahuricae, Cortex Moutan and Radix Polygalae is adjuvant.All medicines are harmonious, tool replenishing YIN and removing heat altogether, the effect of calming the nerves and regulating the flow of vital energy.The treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment alopecia areata of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat alopecia areata, and the prevention of alopecia areata is also had good effect, and the treatment alopecia areata has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment alopecia areata; Treatment alopecia areata patient 28 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.14 examples of fully recovering account for 50%, and 11 examples that take a turn for the better account for 39.29%, and more 3 examples do not account for 10.71%, and total effective rate reaches 89.29%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

2 parts of 2 parts of Radix Paeoniae Rubra of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

1 part of 2 parts of Radix Angelicae Dahuricae of 2 parts of Radix Bupleuri of Fructus Lycii

1 part of 1 part of Radix Polygalae of 1 part of Cortex Moutan of Fructus Corni.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment alopecia areata that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.

Claims (3)

1. Chinese medicine composition for the treatment of alopecia areata is characterized in that it is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Rhizoma Anemarrhenaes of 1.5～6 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

1.0～4 parts of 1.0～4 parts of Radix Paeoniae Rubra of 1.0～4 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

0.1～2 part of 1.0～4 parts of Radix Angelicae Dahuricae of 1.0～4 parts of Radix Bupleuri of Fructus Lycii

0.1～2 part of 0.1～2 part of Radix Polygalae of 0.1～2 part of Cortex Moutan of Fructus Corni.

2. a kind of Chinese medicine composition for the treatment of alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:

2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Anemarrhenaes of 2.5～3.5 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

1.5～2.5 parts of 1.5～2.5 parts of Radix Paeoniae Rubra of 1.5～2.5 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

0.5～1.5 part of 1.5～2.5 parts of Radix Angelicae Dahuricae of 1.5～2.5 parts of Radix Bupleuri of Fructus Lycii

0.5～1.5 part of 0.5～1.5 part of Radix Polygalae of 0.5～1.5 part of Cortex Moutan of Fructus Corni.

3. a kind of Chinese medicine composition for the treatment of alopecia areata according to claim 1, wherein the weight proportion of each crude drug is:

3 parts of 3 parts of Rhizoma Anemarrhenaes of 3 parts of Radix Rehmanniae Preparata of Radix Polygoni Multiflori

2 parts of 2 parts of Radix Paeoniae Rubra of 2 portions of Herba Ecliptaes of Fructus Ligustri Lucidi

1 part of 2 parts of Radix Angelicae Dahuricae of 2 parts of Radix Bupleuri of Fructus Lycii

1 part of 1 part of Radix Polygalae of 1 part of Cortex Moutan of Fructus Corni.