CN101094844B - 苯并二氢吡喃衍生物，药物及其在治疗中的应用 - Google Patents

苯并二氢吡喃衍生物，药物及其在治疗中的应用 Download PDF

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Publication number
CN101094844B
CN101094844B CN2005800380156A CN200580038015A CN101094844B CN 101094844 B CN101094844 B CN 101094844B CN 2005800380156 A CN2005800380156 A CN 2005800380156A CN 200580038015 A CN200580038015 A CN 200580038015A CN 101094844 B CN101094844 B CN 101094844B
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CN
China
Prior art keywords
hydrogen
compound
formula
chroman
phenylor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2005800380156A
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English (en)
Chinese (zh)
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CN101094844A (zh
Inventor
A·希顿
A·J·赫斯本德
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Marshall Edwards Inc
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Marshall Edwards Inc
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Filing date
Publication date
Priority claimed from AU2004906363A external-priority patent/AU2004906363A0/en
Priority claimed from PCT/AU2004/001619 external-priority patent/WO2005049008A1/en
Priority claimed from AU2005201855A external-priority patent/AU2005201855B2/en
Application filed by Marshall Edwards Inc filed Critical Marshall Edwards Inc
Priority claimed from PCT/AU2005/001436 external-priority patent/WO2006032086A1/en
Publication of CN101094844A publication Critical patent/CN101094844A/zh
Application granted granted Critical
Publication of CN101094844B publication Critical patent/CN101094844B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
CN2005800380156A 2004-09-21 2005-09-21 苯并二氢吡喃衍生物，药物及其在治疗中的应用 Expired - Fee Related CN101094844B (zh)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US61129904P 2004-09-21 2004-09-21
US60/611,299 2004-09-21
JP2004315009A JP4976649B2 (ja) 2004-09-21 2004-10-29 化合物
JP315009/2004 2004-10-29
AU2004906363A AU2004906363A0 (en) 2004-11-05 Compounds
AU2004906363 2004-11-05
PCT/AU2004/001619 WO2005049008A1 (en) 2003-11-19 2004-11-19 Combinational radiotherapy and chemotherapy compositions and methods
AUPCT/AU2004/001619 2004-11-19
US67693405P 2005-05-03 2005-05-03
AU2005201855 2005-05-03
AU2005201855A AU2005201855B2 (en) 2004-09-21 2005-05-03 Chroman derived compounds and formulations thereof for use in therapy
US60/676,934 2005-05-03
PCT/AU2005/001436 WO2006032086A1 (en) 2004-09-21 2005-09-21 Chroman derivatives, medicaments and use in therapy

Publications (2)

Publication Number Publication Date
CN101094844A CN101094844A (zh) 2007-12-26
CN101094844B true CN101094844B (zh) 2012-07-25

Family

ID=34956540

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2005800380156A Expired - Fee Related CN101094844B (zh) 2004-09-21 2005-09-21 苯并二氢吡喃衍生物，药物及其在治疗中的应用

Country Status (2)

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JP (3) JP4976649B2 (enExample)
CN (1) CN101094844B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE532777T1 (de) 2004-09-21 2011-11-15 Marshall Edwards Inc Substituierte chromanderivate, medikamente und anwendungen in der therapie
JP4976649B2 (ja) * 2004-09-21 2012-07-18 マーシャル エドワーズ，インク． 化合物
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
US9663484B2 (en) 2010-11-01 2017-05-30 Mei Pharma, Inc. Isoflavonoid compounds and methods for the treatment of cancer
CN103224481A (zh) * 2013-05-20 2013-07-31 黑龙江大学 一种去氢雌马酚的制备方法
SG11201604490SA (en) * 2014-02-07 2016-07-28 Novogen ltd Functionalised benzopyran compounds and use thereof
JP6218680B2 (ja) * 2014-06-11 2017-10-25 三菱電機株式会社 ネットワーク解析支援装置、ネットワーク解析支援方法、および、プログラム
CN107427003B (zh) 2015-02-02 2023-01-31 梅制药公司 联合治疗
CN108409701B (zh) * 2017-02-10 2020-09-25 山东康迈祺生物科技有限公司 一种二氢大豆苷元的制备方法
CN112920173A (zh) * 2021-01-25 2021-06-08 江苏师范大学 一种手性苯并二氢吡喃化合物及其合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883118A (en) * 1996-01-11 1999-03-16 Nova Nordisk A/S Prostatic carcinoma
ATE229519T1 (de) * 1996-10-28 2002-12-15 Novo Nordisk As Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen
IL129623A0 (en) * 1996-10-28 2000-02-29 Novo Nordisk As Novel trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
KR20000001793A (ko) * 1998-06-13 2000-01-15 이경하 신규한 벤조피란 또는 티오벤조피란 유도체
NZ527144A (en) * 2001-01-24 2005-03-24 Chiesi Farmaceutici S 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof
JP4976649B2 (ja) * 2004-09-21 2012-07-18 マーシャル エドワーズ，インク． 化合物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A.N.Booth ET.AL..coumestrol, Plant Phenolics, and Synthetic Estrogens: a Correlation of Structure and Activity.《Journal of Medicinal and Pharmaceutical Chemistry》.1962,第5卷321-35. *
Lawson W. ET.AL..Estrogenic activity of some derivatives of isoflaven and isoflavanol.《Journal of the Chemical Society,Abstracts》.1954,4448-50. *
Teo,Chin Chin ET.AL..Synthesis of 3-(p-fluorophenyl)-4-arylchrom-3-enes as selective ligands for antiestrogen-binding sites.《Journal of Chemical Research,Synopses》.1990,第1卷4-5. *

Also Published As

Publication number Publication date
CN101094844A (zh) 2007-12-26
JP2014237638A (ja) 2014-12-18
JP2006096734A (ja) 2006-04-13
JP4976649B2 (ja) 2012-07-18
JP2012144537A (ja) 2012-08-02
JP5816868B2 (ja) 2015-11-18

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