CN101084925A - Technology for producing pilose antler mother solution - Google Patents
Technology for producing pilose antler mother solution Download PDFInfo
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- CN101084925A CN101084925A CNA2007100424507A CN200710042450A CN101084925A CN 101084925 A CN101084925 A CN 101084925A CN A2007100424507 A CNA2007100424507 A CN A2007100424507A CN 200710042450 A CN200710042450 A CN 200710042450A CN 101084925 A CN101084925 A CN 101084925A
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- antler
- mother liquor
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- cornu cervi
- cervi pantotrichum
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Abstract
The invention relates to a biologic health products, especially to a production technology of antler mother liquor. The production technology comprises removing surfacial and hair from antler, stamping, mixing with pure water at a ratio of 1:5-1:10, heating to 55-65deg.C, keeping at constant temperature, adding proteinase for enzymolysis for 4-8 h until the liquid is yellow clear liquor with light grey, terminating the enzymolysis, pasteurizing, and filtering to obtain final product. The invention adopts external digestion instead of in vivo digestion to decompose antler protein and produce nutritional mother liquor with easy absorption, which relieves load for absorber and makes full use of rare wild animals resource.
Description
Technical field:
The present invention relates to biological health-care product, refer to a kind of production technology of antler mother liquor especially.
Background technology:
Deer platform " Book of Songs " record " king is at the formal volt of Ling You Hunting Garden muntjac deer " that has literature record Zhou king to build " big Samsung, high thousand chis ", the muntjac deer that " being total to it with the people " raises, Cervus nippon Temminck and Cervus elaphus linnaeus are viewed and admired hunting pig, sacrifice and food meat for slave owner.
The pharmacopeia that China is the most ancient--in the Shennong's Herbal, just put down in writing Cornu Cervi Pantotrichum, Cornu Cervi and Colla cornus cervi.Meaning Cornu Cervi Pantotrichum: " sweet, warm, nontoxic ".Cure mainly " stagnant blood that leaks down, cold and heat infantile convulsion, the strong will of QI invigorating ... ".The salty temperature of Cornu Cervi is nontoxic, cures mainly the malignant boil carbuncle, satisfies evil gas, and stagnant blood is in the moon.Colla cornus cervi, different name white glues: sweet, flat, nontoxic, cure mainly that damaging the spleen and stomach labor is exhausted, lumbago is won thin, invigorating the spleen and replenishing QI, married woman's blood closes loss of fecundity, pain relieving is antiabortive.
Compendium of Material Medica meaning: deer is the mountain beast, belong to sun, feelings are excessive and trip mountain, the Summer Solstice get cloudy gas Xie Jiao, from resembling that sun moves back.Abnormal smells from the patient is sweet, warm, nontoxic.It is not old to cure mainly stagnant blood, cold and heat infantile convulsion, the strong will of QI invigorating, the population.
Modern medicine " Chinese materia medica " (Shanghai science and technology version society) Cornu Cervi Pantotrichum-vertebrates Cervidae, the still unossified and young horn of band hair on the stag heads such as Cervus nippon Temminck or Cervus elaphus linnaeus.
Its meridian distribution of property and flavor, sweet, salty, warm, return Liver Channel, kidney channel.Effect: kidney-replenishing, bone and muscle strengthening.Use: (1) is used for that insufficiency of kidney-YANG, essence and blood lose that aversion to cold and cold limbs, impotence and premature ejaculation, the cold womb of void is infertile, frequent micturition, soreness of waist and knee joint, have a dizzy spell, deaf, spiritual disease such as tired.(2) be used for asthenia of essence and blood, muscles and bones is unable or dysplasia of children, the soft walking retardation in children of bone, forehead such as do not conform at disease.(3) be used for that women's cold and deficiency of CHONG and REN meridians, dai channel are solid, metrorrhagia is more than, leukorrhagia is too much.
Find through experiment:
Dried Cornu Cervi Pantotrichum water content 12.11%, Organic substance 63.44%, ash 24.45%, bright Cornu Cervi Pantotrichum water content 56.5%, Organic substance 20%, ash 23.5%.Be rich in metallic element in the Cornu Cervi Pantotrichum, wherein as: calcium 10.6%, ferrum 0.051%, magnesium 0.25%, silver 0.001%, copper 0.0007%, silicon 0.007%, strontium 0.2%, zinc 0.005%, manganese 0.003%, sodium 0.43%..........Strong the lengthening one's life of these favourable human bodies increases intelligence ... obligato complementary element.
Cornu Cervi Pantotrichum also has the body of adjustment metabolism, defying age and strong effect (take passages and support deer and deer product New Machining Technology-Chinese agriculture publishing house).
1, defying age.Superoxide dismutase (SOD) is active must to be acted on the inhibition lipid peroxidation modern medicine proof Cornu Cervi Pantotrichum by strengthening, and can improve the oxidation resistance of body, so Cornu Cervi Pantotrichum has defying age, and the effect of life lengthening.
2, promote nucleic acid and protease matter synthetic.The polyamines class material of Cornu Cervi Pantotrichum is to promote nucleic acid and the synthetic effective ingredient of protease matter.The fine and soft point of three polyamine species content of material is higher than middle part and root, and its mechanism of action mainly is RNA---the activity of polymerase II of cell cultured supernatant nuclear, thereby improves the aggregate velocity of protein and RNA.Played the pharmacological action of strong body.
3, strong effect.Cornu Cervi Pantotrichum has multiple strong effect as Radix Ginseng to body.As: resisting fatigue, anti-stress, promotion nucleic acid and protein synthesis, adrenal cortex reinforcing function, the healing of acceleration of wound and sclerotin ...The research of modern medicine fully confirms, Cornu Cervi Pantotrichum is used for strong, the kidney invigorating, tonifying YANG as traditional tonic.
4, protection cardiac system.The pantocrine that Cornu Cervi Pantotrichum extracts can strengthen the blood supply of heart, strengthens cardiac contractile force, and decreased heart rate has significant protective effect to all kinds of drug-induced ventricular fibrillation.Cornu Cervi Pantotrichum is remarkable to tired heart effect especially, can make it recover normal to cacorhythmic isolated heart.
5, improve sexual function.Cornu Cervi Pantotrichum is all effective to the treatment of hebetic sexual disorder and strong senile atrophy of prostate disease, and treatment produces effect to the Women obstacle.The proof Cornu Cervi Pantotrichum can significantly improve sexual function, strengthen sexual function.
6, other, Cornu Cervi Pantotrichum has strengthening gastrointestinal peristalsis and secretion function, promotes appetite, improves sleep, strengthens effects such as diuresis and memory.
To sum up; because the development of modern medicine means; through clinical research and zoopery; confirm that sika deer velvet antler (cervus elaphus linnaeus etc.) and goods thereof have the immunologic function of raising defying age, resisting fatigue, sexual function improving; good efficacy such as protection heart are a kind of health care, prevention, all good new special biological product of therapeutical effect.
Since ancient times, China's custom Chinese liquor infuse piece of antler (bright, dried).But in the wine a large amount of precipitate can appear, after drinking, the people can not fully absorb, common in the market deer antler wine product, the main raw material that adopts aquatic foods, dried Cornu Cervi Pantotrichum to handle without the aspects such as health of any strictness, because the bright moisture 56%-65% of (doing) Cornu Cervi Pantotrichum (10%-15%), Organic substance accounts for 20% (60%-65%) its nutritional labeling and mainly contains protein, polypeptide, aminoacid etc.Physiology digestion circulation angle analysis from human body: after taking Cornu Cervi Pantotrichum, will be subjected to pepsic enzyme Jie digestion earlier, to the enteral absorption, its degree of absorption depends on the power of enzyme Jie function fully again.Therefore, have only Partial Protein to be absorbed, and most of the drainage.For the consumer of weak, invalid digestive function difference, nutrition utilize power lower.
To sum up existing deer antler wine and its production technology of goods thereof have the following disadvantages:
1, existing deer antler wine mainly adopts aquatic foods (doing) to give birth to piece of antler owing to aspect reasons such as health.There are pathogenic bacterium, health is had potential harm.
2, prior art is handled bright (doing) piece of antler without biological engineering, and human body clothes post-absorption rate is low, has wasted wildlife resource.
Summary of the invention:
Technical problem solved by the invention has overcome the defective in the above-mentioned existing piece of antler goods, is converted into micromolecule from molecules angle macromole, makes the easier absorption of human body.
The present invention becomes that tradition section infuse is got or boiling is got or pulverized and gets nutrition or material object and be converted into biological engineering and directly produce the Cornu Cervi Pantotrichum nutritional solution.
Concrete technical solution of the present invention is as follows:
A kind of production technology of antler mother liquor comprises:
Step 1 is removed Cornu Cervi Pantotrichum epidermis oil and hair, is smashed processing to pieces;
Step 2, above-mentioned steps one products therefrom and pure water is even with 1: 5~1: 10 mixed, be heated to 55 ℃-65 ℃, keep constant temperature, add protease and carry out enzymolysis processing, enzymolysis reaction when successive reaction 4~8 hours to liquid is light lark clear liquor is carried out pasteurized process, promptly obtains antler mother liquor after filtering.
Above-mentioned raw material Cornu Cervi Pantotrichum is bright Cornu Cervi Pantotrichum or dried Cornu Cervi Pantotrichum.
In the above-mentioned tandem reaction sequence, keeping constantly replenishing the adding pure water under the constant condition of total liquid measure.
Above-mentioned protease is papain.
The vigor of above-mentioned papain should be greater than 1,000,000 μ/g.
Above-mentionedly mother liquid obtainedly can be condensed into variable concentrations as required, proportioning becomes manufactured goods such as medicated wine, unguentum, soft sweet, oral liquid then.
The enzyme activity unit of more than addressing (U, active unit) is a biochemical professional term: the measuring of enzyme activity unit.International zymetology meeting regulation in 1961: 1 enzyme activity unit is meant (25 ℃ of specified conditions, other is an optimal condition) under, in 1min, can transform the enzyme amount of 1 μ mol substrate, or the enzyme amount of the relevant group of 1 μ mol in the conversion of substrate, be 1 enzyme activity unit.This enzyme activity unit claims iu again, and unit is μ mol/min.
But the definition of enzyme activity in the practical application, some is convenient for using, some is to continue to use custom.Though the enzyme activity numerical value of different definition there are differences, as long as assay method is identical with condition determination, the back of converting just can directly be compared.
According to the enzymolysis material that uses in the market, following statement is taked in the statement of its specification unit usually:
Solid-state enzymolysis material unit is μ/g, and liquid enzymolysis material unit is μ/ml.
For example, cellulase, its solid-state unit is 10000 μ/g, 20000 μ/g; Liquid unit is 10000 μ/ml, and the unit of the refining protease of 20000 μ/ml. is 130000 μ/g, and the unit of papain is 2000000 μ/g.
Above-mentioned enzyme activity unit can with reference to write by Jiang Xirui, Duan Gang " newly organized enzyme preparation practical technique handbook, Beijing China Light Industry Press publishes the 11st page, the 57th page in March, 2002.
Technique effect of the present invention can see the following form, and organic principle is expressed as follows (%).
Title | Content | Effect |
Protein | Total amount 37.3mg/ml | |
Aminoacid | Total amount 27500 μ g/g |
Door winter amino | 0.127 | Promote carbamide to generate, fall blood ammonia, improve liver function |
Threonine | 0.086 | Anti-fatty liver, treatment anemia |
Serine | 0.125 | Antitumor |
Glutamic acid | 0.394 | Improve high blood nitrogen disease, treatment hepatic coma |
Proline | 0.193 | |
Glycine | 0.301 | Treatment muscle disease, hyperchlorhydria |
Alanine | 0.183 | The protection gastric mucosa |
Cystine | 0.0162 | Promote hair growth, prevent hepatitis, increase giant cell |
Valine | 0.103 | |
Methionine | 0.0130 | |
Isoleucine | 0.0397 | Promote growth promoter |
Leucine | 0.229 | Keep fatty homergy |
Tyrosine | 0.0270 | The prevention hyperammonemia |
Phenylalanine | 0.0749 | |
Lysine | 0.116 | Promote growth promoter |
Histidine | 0.0305 | Calm parasympathetic nervous, the treatment peptic ulcer |
Tryptophan | / | |
Arginine | 0.136 | Promote urine circulation, treatment hepatic coma |
The present invention adopts external digestion to substitute enzyme Jie process means of digestion in the body, and Cornu Cervi Pantotrichum protein cleavage and amino acids nutritious mother liquid are generated, and consumer is directly absorbed, and alleviates the interior burden of absorber's body and makes full use of precious wildlife resource again.
As long as enzymolysis time, all conditions such as temperature are suitable, the simulated in vivo environment of trying one's best, and the nutritious mother liquid of its formation can fully be absorbed by human body, the absorption that has also kept other each effective constituents simultaneously.
The specific embodiment:
Can further be well understood to the present invention by specific embodiments of the invention given below, but they not limitation of the invention.
Embodiment 1:
A kind of bright production technology of antler mother liquor comprises:
Step 1 is removed bright Cornu Cervi Pantotrichum epidermis oil and hair, is smashed processing to pieces;
Step 2, above-mentioned steps one products therefrom and pure water is even with 1: 5 mixed, be heated to 65 ℃ of constant temperature, the papain (day sunset, outstanding energy section produced) that adds 2 ‰ liquid gross weights carries out enzymolysis processing, and the vigor of above-mentioned papain is 2,000,000 μ/g.Add pure water keeping constantly replenishing under the constant condition of total liquid measure, enzymolysis reaction when successive reaction 4~5 hours to liquid is light lark clear liquor is carried out pasteurized process, promptly obtains bright antler mother liquor after filtering.
Embodiment 2
A kind of dried production technology of antler mother liquor comprises:
Step 1 is removed Cornu Cervi Pantotrichum epidermis oil and hair, is smashed processing to pieces;
Step 2, above-mentioned steps one products therefrom and pure water is even with 1: 10 mixed, be heated to 55 ℃ of constant temperature, the papain (day sunset, outstanding energy section produced) that adds 1 ‰ liquid gross weights carries out enzymolysis processing, and the vigor of above-mentioned papain is 2,000,000 μ/g.Add pure water keeping constantly replenishing under the constant condition of total liquid measure, enzymolysis reaction when successive reaction 7~8 hours to liquid is light lark clear liquor is carried out pasteurized process, promptly obtains antler mother liquor after filtering.
Although the present invention has been done detailed explanation and has quoted some specific embodiments as proof, to those skilled in the art, only otherwise leaving the spirit and scope of the present invention can be obvious as various changes and modifications.
Claims (6)
1, a kind of production technology of antler mother liquor,
Step 1 is removed Cornu Cervi Pantotrichum epidermis oil and hair, is smashed processing to pieces;
Step 2, above-mentioned steps one products therefrom and pure water is even with 1: 5~1: 10 mixed, be heated to 55 ℃-65 ℃, keep constant temperature, add protease and carry out enzymolysis processing, enzymolysis reaction when successive reaction 4~8 hours to liquid is light lark clear liquor is carried out pasteurized process, promptly obtains antler mother liquor after filtering.
2, production technology of antler mother liquor according to claim 1 is characterized in that described raw material Cornu Cervi Pantotrichum is bright Cornu Cervi Pantotrichum or dried Cornu Cervi Pantotrichum.
3, production technology of antler mother liquor according to claim 1 is characterized in that in the described tandem reaction sequence, is keeping constantly replenishing the adding pure water under the constant condition of total liquid measure.
4, production technology of antler mother liquor according to claim 1 is characterized in that described protease is papain.
5, production technology of antler mother liquor according to claim 4 is characterized in that the vigor of described papain should be greater than 1,000,000 μ/g.
6, production technology of antler mother liquor according to claim 1 is characterized in that describedly mother liquid obtainedly can being condensed into variable concentrations as required, and proportioning becomes manufactured goods such as medicated wine, unguentum, soft sweet, oral liquid then.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102286561A (en) * | 2011-07-11 | 2011-12-21 | 长春工业大学 | Method for extracting active ingredients of fresh pilos antler through enzymatic degradation |
CN102399665A (en) * | 2010-09-13 | 2012-04-04 | 温州士福梅花鹿养殖有限公司 | Process for preparing wine from fresh spotted deer antler through enzymolysis |
CN102805199A (en) * | 2012-08-26 | 2012-12-05 | 吉林省中韩动物科学研究院 | Method for preparing pilose antler protein calcium product |
CN106177317A (en) * | 2016-07-29 | 2016-12-07 | 中国农业科学院特产研究所 | A kind of warming the kidney to invigorate YANG, the instant Cornu Cervi Pantotrichum sheet and preparation method thereof of strengthening the tendons and bones |
CN115996645A (en) * | 2020-06-30 | 2023-04-21 | 庆尚国立大学校 产学协力团 | Composition for preventing, improving or treating diseases caused by nitration of tyrosine in protein comprising tyrosine as active ingredient |
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CN106177325A (en) * | 2016-07-29 | 2016-12-07 | 中国农业科学院特产研究所 | A kind of instant Cornu Cervi Pantotrichum sheet improving immunity and preparation method thereof |
Family Cites Families (2)
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CN1193770C (en) * | 2003-01-09 | 2005-03-23 | 长春市双阳区鹿业科学技术研究所 | Hydrolytic extrating method for medicinal component of pilose antler |
CN100425270C (en) * | 2006-03-02 | 2008-10-15 | 魏峰 | Semifluid extract of deer foetus and preparing method |
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- 2007-06-22 CN CN2007100424507A patent/CN101084925B/en not_active Expired - Fee Related
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102399665A (en) * | 2010-09-13 | 2012-04-04 | 温州士福梅花鹿养殖有限公司 | Process for preparing wine from fresh spotted deer antler through enzymolysis |
CN102286561A (en) * | 2011-07-11 | 2011-12-21 | 长春工业大学 | Method for extracting active ingredients of fresh pilos antler through enzymatic degradation |
CN102286561B (en) * | 2011-07-11 | 2015-05-13 | 长春工业大学 | Method for extracting active ingredients of fresh pilos antler through enzymatic degradation |
CN102805199A (en) * | 2012-08-26 | 2012-12-05 | 吉林省中韩动物科学研究院 | Method for preparing pilose antler protein calcium product |
CN102805199B (en) * | 2012-08-26 | 2016-08-03 | 吉林省中韩动物科学研究院 | The method of preparation pilose antler protein calcium product |
CN106177317A (en) * | 2016-07-29 | 2016-12-07 | 中国农业科学院特产研究所 | A kind of warming the kidney to invigorate YANG, the instant Cornu Cervi Pantotrichum sheet and preparation method thereof of strengthening the tendons and bones |
CN115996645A (en) * | 2020-06-30 | 2023-04-21 | 庆尚国立大学校 产学协力团 | Composition for preventing, improving or treating diseases caused by nitration of tyrosine in protein comprising tyrosine as active ingredient |
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