CN101072879B - 改良的腺病毒载体及其应用 - Google Patents

改良的腺病毒载体及其应用 Download PDF

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CN101072879B
CN101072879B CN2005800351365A CN200580035136A CN101072879B CN 101072879 B CN101072879 B CN 101072879B CN 2005800351365 A CN2005800351365 A CN 2005800351365A CN 200580035136 A CN200580035136 A CN 200580035136A CN 101072879 B CN101072879 B CN 101072879B
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vectors
vector
adenovirus
seq
hexon
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CN101072879A (zh
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曼佐·扬斯·埃姆科·海文加
丹·巴罗什
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Janssen Vaccines and Prevention BV
Beth Israel Deaconess Medical Center
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Crucell Holand BV
Beth Israel Deaconess Medical Center
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
    • C12N2810/6018—Adenoviridae

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN2005800351365A 2004-10-13 2005-10-12 改良的腺病毒载体及其应用 Expired - Fee Related CN101072879B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US61846904P 2004-10-13 2004-10-13
EP04105005.5 2004-10-13
US60/618,469 2004-10-13
EP04105005 2004-10-13
US69772405P 2005-07-08 2005-07-08
US60/697,724 2005-07-08
PCT/EP2005/055183 WO2006040330A2 (en) 2004-10-13 2005-10-12 Improved adenoviral vectors and uses thereof

Publications (2)

Publication Number Publication Date
CN101072879A CN101072879A (zh) 2007-11-14
CN101072879B true CN101072879B (zh) 2011-05-11

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CN2005800351365A Expired - Fee Related CN101072879B (zh) 2004-10-13 2005-10-12 改良的腺病毒载体及其应用

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JP (1) JP4843613B2 (enExample)
CN (1) CN101072879B (enExample)
AT (1) ATE492643T1 (enExample)
DE (1) DE602005025512D1 (enExample)
ES (1) ES2358523T3 (enExample)
ZA (1) ZA200702792B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111108192A (zh) * 2017-07-05 2020-05-05 Nouscom股份公司 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途

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HUE039908T2 (hu) * 2009-02-02 2019-02-28 Glaxosmithkline Biologicals Sa Majom adenovírusból származó nukleinsav- és aminosav-szekvenciák, azt tartalmazó vektorok és alkalmazásuk
WO2011022002A1 (en) * 2009-08-18 2011-02-24 The Rockefeller University Modification of recombinant adenovirus with immunogenic plasmodium circumsporozoite protein epitopes
EP2558481B1 (en) * 2010-04-14 2017-12-20 Mogam Biotechnology Research Institute Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using the same
KR101879892B1 (ko) * 2010-12-14 2018-08-17 더 거버먼트 오브 더 유나이티드 스테이츠 오브 아메리카 에즈 레프리젠티드 바이 더 세크러테리 오브 더 디파트먼트 오브 헬스 앤드 휴먼 서비시즈 아데노바이러스 혈청형 26 및 혈청형 35 필로바일러스 백신
CN102199616B (zh) * 2011-03-07 2013-04-24 首都医科大学附属北京佑安医院 Hiv-1表型耐药检测载体及其构建方法
CA2850627C (en) * 2011-10-05 2024-05-21 Genvec, Inc. Affenadenovirus (gorilla) or adenoviral vectors and methods of use
JP5845376B2 (ja) * 2012-03-22 2016-01-20 クルセル ホランド ベー ヴェー Ｒｓｖに対するワクチン
JP7032304B2 (ja) 2015-07-28 2022-03-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア キメラ抗原受容体を発現する改変された単球／マクロファージおよびその使用
AU2017375633C1 (en) * 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN106868047B (zh) * 2017-03-07 2020-04-28 南方医科大学 一种重组腺病毒载体及其构建方法和用途
CN107267469B (zh) * 2017-08-22 2020-06-16 广州医科大学附属第一医院 纤毛蛋白嵌合型重组人b型腺病毒及其制备方法
MX421606B (es) * 2017-10-31 2025-03-14 Janssen Vaccines & Prevention Bv Vectores adenovirales y usos de estos
MX2020004488A (es) * 2017-10-31 2020-08-13 Janssen Vaccines & Prevention Bv Adenovirus y usos de estos.
CA3095179A1 (en) 2018-04-03 2019-10-10 Stridebio, Inc. Antibody-evading virus vectors
IL283165B2 (en) * 2018-11-21 2024-12-01 Mayo Found Medical Education & Res Adenoviruses and methods for using adenoviruses
US11542526B2 (en) * 2019-02-21 2023-01-03 Unleash Immuno Oncolytics, Inc. Oncolytic adenoviral vector and methods of use
EP4161536A4 (en) 2020-06-04 2024-08-14 Carisma Therapeutics Inc. Novel constructs for chimeric antigen receptors
CN114262692A (zh) * 2021-11-30 2022-04-01 华中科技大学同济医学院附属同济医院 一种携带tmvp1和hsv-tk的溶瘤腺病毒重组体，其构建方法及应用

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US5922315A (en) * 1997-01-24 1999-07-13 Genetic Therapy, Inc. Adenoviruses having altered hexon proteins
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111108192A (zh) * 2017-07-05 2020-05-05 Nouscom股份公司 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途
CN111108192B (zh) * 2017-07-05 2023-12-15 Nouscom股份公司 非人类人猿腺病毒核酸序列和氨基酸序列、含有其的载体及其用途

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CN101072879A (zh) 2007-11-14
ZA200702792B (en) 2007-12-27
ES2358523T3 (es) 2011-05-11
DE602005025512D1 (de) 2011-02-03
JP2009523007A (ja) 2009-06-18
ATE492643T1 (de) 2011-01-15
JP4843613B2 (ja) 2011-12-21

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