CN101066341A - Chinese medicine composition for treating metrorrhagia - Google Patents

Abstract

The present invention provides Chinese medicine composition for treating metrorrhagia. The Chinese medicine composition is prepared with over ten kinds of Chinese medicinal materials, including lotus rhizome, palm charcoal, garden burnet, wolfberry bark, etc. It has the functions of clearing away heat, cooling blood, arresting bleeding and regulating menstruation. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine composition has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

A kind of Chinese medicine composition for the treatment of metrorrhagia

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of metrorrhagia, is that a kind of to treat metrorrhagia be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Menopathy is meant cycle, the menstrual period and unusual through the amount generation of all menstruations, and follows menstrual cycle the significant discomfort symptom to occur, or the relevant a series of symptoms that occurred before and after menopause are a class disease of feature.The women is not between menstrual period, and vagina is bled profusely suddenly, or the continuous person of dripping hematochezia, is called " metrorrhagia ".The former is called " metrorrhagia ", and the latter is called " leaking down ".If menostaxis reaches above person of 2 weeks, should belong to the metrorrhagia category, be called " metrorrhagia " or " menometrorrhagia ".General unexpected hemorrhage, the oncoming force is anxious, and crying that blood volume is many collapsed; Dripping hematochezia, the oncoming force is slow, and what blood volume was few cries Lou.Though the hemorrhage situation that collapses and leak is inequality, pathogeny is consistent, and normal conversion mutually in the advancing of disease process, and as metrorrhagia with the passing of time, QI and blood consumes hinders, and becomes leakage; Leak incessantly for a long time, patient's condition day advances, and also can become to collapse.So usually metrorrhagia also claims clinically.Say as recipes for Saving Lives: " disease of metrorrhagia, this card.Leaking down of the lighter's meaning, the very metrorrhagia of person's meaning." primary disease belongs to commonly encountered diseases, Chang Yin collapses and leaks alternately, and cause and effect is relevant, causes the touching difficulty of pathological changes more, becomes the difficult serious symptom of gynecological.Primary disease is equivalent to the irregular vagina bleeding that western medicine anovulation type dysfunctional uterine bleeding, edeitis and some neoplasmata genitalis cause.Main pathogenesis is the debility of CHONG and REN meridians, can not restrict menses.The common cause that causes the debility of CHONG and REN meridians suffers from a deficiency of the kidney, insufficiency of the spleen, heat in blood and blood stasis.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of metrorrhagia.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

Give birth to 1.5～6 parts of 1.5～6 portions of Concha Ostreaes of 1.5～6 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

1.0～4 parts of 1.0～4 portions of Radix Sanguisorbaes of 1.0～4 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

1.0～4 parts of 1.0～4 parts of Radix Adenophorae (Radix Glehniae) of 1.0～4 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

0.1～2 part of 0.1～2 part of Radix Scutellariae of 1.0～4 portions of Cortex Phellodendris of Cortex Lycii

The weight proportion of each raw material of optimization formula of the present invention is:

Give birth to 2.5～3.5 parts of 2.5～3.5 portions of Concha Ostreaes of 2.5～3.5 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

1.5～2.5 parts of 1.5～2.5 portions of Radix Sanguisorbaes of 1.5～2.5 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

1.5～2.5 parts of 1.5～2.5 parts of Radix Adenophorae (Radix Glehniae) of 1.5～2.5 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

0.5～1.5 part of 0.5～1.5 part of Radix Scutellariae of 1.5～2.5 portions of Cortex Phellodendris of Cortex Lycii

The weight proportion of each raw material of optimum formula of the present invention is:

Give birth to 3 parts of 3 portions of Concha Ostreaes of 3 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

2 parts of 2 portions of Radix Sanguisorbaes of 2 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

2 parts of 2 parts of Radix Adenophorae (Radix Glehniae) of 2 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

1 part of 1 part of Radix Scutellariae of 2 portions of Cortex Phellodendris of Cortex Lycii

Drug action mechanism among the present invention is as follows:

It is sweet, puckery to give birth to the Nodus Nelumbinis Rhizomatis property of medicine, flat.Return liver, lung, stomach warp.Has dissipating blood stasis hemostatic effect.Can treat haematemesis, spitting of blood, hematuria is had blood in stool, dysentery, metrorrhagia etc.(the 3799th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The CARAPAX ET PIASTRUM TESTUDINIS PREPARATA property of medicine is salty, sweet, is slightly cold.Return liver, kidney, heart channel.Has nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, heart tonifying and tranquilizing, the effect of consolidating channel for hemostasis.Can treat deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat is had a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and wriggling of the limbs, a little less than the muscles and bones flaccidity, children's's halogen door does not conform to, and the palpitation with fear insomnia is forgetful, menorrhagia, metrorrhagia and metrostaxis.(the 1608th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Concha Ostreae property of medicine is salty, is slightly cold.Return liver, kidney channel.Have suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating effect.Can treat vertigo and tinnitus, palpitation with fear insomnia, scrofula goiter ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission, metrorrhagia, leukorrhagia etc.(the 1574th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Charred Petiolus Trachycarpi nature and flavor hardship, puckery, flat.Return lung, liver, large intestine channel.Effect with hemostasis with astringents.Can treat haematemesis, epistaxis, hematuria is had blood in stool, metrostaxis etc.(the 276th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Sanguisorbae property of medicine hardship, acid are slightly cold.Return liver, stomach, large intestine channel.Has cooling blood for hemostasis, the effect of heat-clearing and toxic substances removing.Can treat haematemesis, spitting of blood, epistaxis, hematuria, have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting etc.(the 1127th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

Sweet, the little hardship of the Caulis Polygoni Multiflori property of medicine, flat.GUIXIN, Liver Channel.Has tranquilizing by nourishing the heart, the effect of dispelling wind and removing obstruction in the collateral.But Cure for insomnia, dreaminess, blood deficiency general pain, numbness of the skin, rheumatic arthralgia, rubella pruritus etc.(the 2033rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of Radix Adenophorae (Radix Glehniae) property of medicine is slightly cold.Attach to the lung and stomach meridians.Has replenishing YIN and removing heat, moistening the lung and resolving phlegm, the effect of reinforcing stomach reg fluid.Can treat deficiency of YIN chronic cough, the consumptive disease expectorant blood of coughing, cough caused by dryness expectorant is few, the deficiency-heat sore throat, Tianjin wound is thirsty etc.(the 1626th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Cortex Lycii property of medicine is sweet, and is cold.Return lung, kidney channel.Has clearind deficient heat, purte the white, the effect of removing heat from blood.Can treat hectic fever due to deficiency of YIN, hectic fever due to YIN-deficiency night sweat, the infantile malnutrition heating, dyspnea and cough due to lung-heat, haematemesis, epistaxis, hematuria are quenched one's thirst etc.(the 1141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with giving birth to Nodus Nelumbinis Rhizomatis, CARAPAX ET PIASTRUM TESTUDINIS PREPARATA and Concha Ostreae; With charred Petiolus Trachycarpi, Fructus Gardeniae (parched), Radix Sanguisorbae, Radix Rehmanniae, Caulis Polygoni Multiflori, Radix Adenophorae (Radix Glehniae) and Cortex Lycii is ministerial drug; With Cortex Phellodendri and Radix Scutellariae is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat and cooling blood, the effect of blood-arresting catamenia-regulating.The treatment metrorrhagia has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment metrorrhagia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat metrorrhagia, and the prevention of metrorrhagia is also had good effect, and the treatment metrorrhagia has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment metrorrhagia; Treatment metrorrhagia patient 21 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.11 examples of fully recovering account for 52.38%, and 7 examples that take a turn for the better account for 33.33%, and more 3 examples do not account for 14.29%, and total effective rate reaches 85.71%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

Give birth to 3 parts of 3 portions of Concha Ostreaes of 3 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

2 parts of 2 portions of Radix Sanguisorbaes of 2 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

2 parts of 2 parts of Radix Adenophorae (Radix Glehniae) of 2 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

1 part of 1 part of Radix Scutellariae of 2 portions of Cortex Phellodendris of Cortex Lycii

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment metrorrhagia that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of metrorrhagia is characterized in that it is made by the following weight proportion raw material:

Give birth to 1.5～6 parts of 1.5～6 portions of Concha Ostreaes of 1.5～6 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

1.0～4 parts of 1.0～4 portions of Radix Sanguisorbaes of 1.0～4 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

1.0～4 parts of 1.0～4 parts of Radix Adenophorae (Radix Glehniae) of 1.0～4 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

0.1～2 part of 0.1～2 part of Radix Scutellariae of 1.0～4 portions of Cortex Phellodendris of Cortex Lycii.

2, a kind of Chinese medicine composition for the treatment of metrorrhagia according to claim 1, wherein the weight proportion of each raw material is:

Give birth to 2.5～3.5 parts of 2.5～3.5 portions of Concha Ostreaes of 2.5～3.5 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

1.5～2.5 parts of 1.5～2.5 portions of Radix Sanguisorbaes of 1.5～2.5 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

1.5～2.5 parts of 1.5～2.5 parts of Radix Adenophorae (Radix Glehniae) of 1.5～2.5 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

0.5～1.5 part of 0.5～1.5 part of Radix Scutellariae of 1.5～2.5 portions of Cortex Phellodendris of Cortex Lycii.

3, a kind of Chinese medicine composition for the treatment of metrorrhagia according to claim 1, wherein the weight proportion of each raw material is:

Give birth to 3 parts of 3 portions of Concha Ostreaes of 3 parts of CARAPAX ET PIASTRUM TESTUDINIS PREPARATAs of Nodus Nelumbinis Rhizomatis

2 parts of 2 portions of Radix Sanguisorbaes of 2 parts of Fructus Gardeniae (parched) of charred Petiolus Trachycarpi

2 parts of 2 parts of Radix Adenophorae (Radix Glehniae) of 2 parts of Caulis Polygoni Multiflori of Radix Rehmanniae

1 part of 1 part of Radix Scutellariae of 2 portions of Cortex Phellodendris of Cortex Lycii.