CN101052386A - 儿科使用的基于nk2拮抗剂的药物组合物 - Google Patents

儿科使用的基于nk2拮抗剂的药物组合物 Download PDF

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Publication number
CN101052386A
CN101052386A CNA2005800370703A CN200580037070A CN101052386A CN 101052386 A CN101052386 A CN 101052386A CN A2005800370703 A CNA2005800370703 A CN A2005800370703A CN 200580037070 A CN200580037070 A CN 200580037070A CN 101052386 A CN101052386 A CN 101052386A
Authority
CN
China
Prior art keywords
methyl
piperidines
base
ring
carbamyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800370703A
Other languages
English (en)
Chinese (zh)
Inventor
阿尔波特·阿罗蒂
玛芮拉·奥特缪拉
卡罗·阿尔波特·麦琪
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Guidotti SpA
Original Assignee
Laboratorio Guidotti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Guidotti SpA filed Critical Laboratorio Guidotti SpA
Publication of CN101052386A publication Critical patent/CN101052386A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CNA2005800370703A 2004-10-27 2005-10-26 儿科使用的基于nk2拮抗剂的药物组合物 Pending CN101052386A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000221A ITFI20040221A1 (it) 2004-10-27 2004-10-27 Composizioni farmaceutiche a base di nk2 antagonisti per uso pediatrico
ITFI2004A000221 2004-10-27

Publications (1)

Publication Number Publication Date
CN101052386A true CN101052386A (zh) 2007-10-10

Family

ID=35613882

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800370703A Pending CN101052386A (zh) 2004-10-27 2005-10-26 儿科使用的基于nk2拮抗剂的药物组合物

Country Status (25)

Country Link
US (2) US7727955B2 (enExample)
EP (1) EP1809267B1 (enExample)
JP (1) JP2008517977A (enExample)
CN (1) CN101052386A (enExample)
AR (1) AR051595A1 (enExample)
AT (1) ATE422881T1 (enExample)
AU (1) AU2005298629B2 (enExample)
CA (1) CA2584481C (enExample)
CY (1) CY1109803T1 (enExample)
DE (1) DE602005012857D1 (enExample)
DK (1) DK1809267T3 (enExample)
EA (1) EA012264B1 (enExample)
ES (1) ES2325413T3 (enExample)
HR (1) HRP20090225T1 (enExample)
IT (1) ITFI20040221A1 (enExample)
MX (1) MX2007004461A (enExample)
NO (1) NO338586B1 (enExample)
NZ (1) NZ555380A (enExample)
PL (1) PL1809267T3 (enExample)
PT (1) PT1809267E (enExample)
RS (1) RS50780B (enExample)
SI (1) SI1809267T1 (enExample)
UA (1) UA91988C2 (enExample)
WO (1) WO2006045820A1 (enExample)
ZA (1) ZA200703909B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104507476A (zh) * 2012-07-12 2015-04-08 里拉通生产企业 含奈帕坦特的儿科口服液体组合物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0614970D0 (en) * 2006-07-27 2006-09-06 R & D Sosei Ltd Compounds For Use In Therapy
IT1394304B1 (it) * 2009-05-21 2012-06-06 Malesci Sas Processo per la preparazione di ibodutant (men15596) e relativi intermedi
US9867857B2 (en) 2014-08-21 2018-01-16 Food Industry Research And Development Institute Acetobacter and gluconacetobacter strains and their metabolites for use in inhibiting xanthine oxidase
US20160051596A1 (en) * 2014-08-21 2016-02-25 Food Industry Research And Development Institute Novel acetobacter and gluconacetobacter strains and their metabolites for use in inhibiting xanthine oxidase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0219318A (ja) * 1988-06-30 1990-01-23 Carl R Thornfeldt 疝痛及び生歯に対する治療
IT1277835B1 (it) 1995-03-13 1997-11-12 Menarini Farma Ind Composti biciclici, loro preparazione ed uso in composizioni farmaceutiche
IT1307809B1 (it) * 1999-10-21 2001-11-19 Menarini Ricerche Spa Composti monociclici basici ad azione nk-2 antagonista, processi difabbricazione e formulazioni che li contengono.
MY130373A (en) * 2001-10-29 2007-06-29 Malesci Sas Linear basic compounds having nk-2 antagonist activity and formulations thereof
GB0224788D0 (en) 2002-10-24 2002-12-04 Novartis Ag Organic compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104507476A (zh) * 2012-07-12 2015-04-08 里拉通生产企业 含奈帕坦特的儿科口服液体组合物
CN104507476B (zh) * 2012-07-12 2017-10-17 里拉通生产企业 含奈帕坦特的儿科口服液体组合物

Also Published As

Publication number Publication date
US20100234284A1 (en) 2010-09-16
CY1109803T1 (el) 2014-09-10
PL1809267T3 (pl) 2009-07-31
MX2007004461A (es) 2007-07-11
NO338586B1 (no) 2016-09-12
CA2584481A1 (en) 2006-05-04
WO2006045820A1 (en) 2006-05-04
ZA200703909B (en) 2008-09-25
EA200700949A1 (ru) 2007-10-26
DE602005012857D1 (de) 2009-04-02
JP2008517977A (ja) 2008-05-29
EA012264B1 (ru) 2009-08-28
NO20072720L (no) 2007-07-09
UA91988C2 (ru) 2010-09-27
EP1809267A1 (en) 2007-07-25
ATE422881T1 (de) 2009-03-15
DK1809267T3 (da) 2009-05-18
NZ555380A (en) 2008-12-24
PT1809267E (pt) 2009-05-28
AR051595A1 (es) 2007-01-24
EP1809267B1 (en) 2009-02-18
RS50780B (sr) 2010-08-31
US7727955B2 (en) 2010-06-01
HK1109335A1 (en) 2008-06-06
HRP20090225T1 (hr) 2009-05-31
AU2005298629A1 (en) 2006-05-04
ES2325413T3 (es) 2009-09-03
ITFI20040221A1 (it) 2005-01-27
US20080090795A1 (en) 2008-04-17
CA2584481C (en) 2014-07-15
AU2005298629B2 (en) 2011-02-17
SI1809267T1 (sl) 2009-06-30

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Open date: 20071010