CN101049475A - Preparation of Chinese traditional medicine for treating barrenness caused by no sperm - Google Patents

Preparation of Chinese traditional medicine for treating barrenness caused by no sperm Download PDF

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Publication number
CN101049475A
CN101049475A CN 200710099247 CN200710099247A CN101049475A CN 101049475 A CN101049475 A CN 101049475A CN 200710099247 CN200710099247 CN 200710099247 CN 200710099247 A CN200710099247 A CN 200710099247A CN 101049475 A CN101049475 A CN 101049475A
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China
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parts
radix
chinese medicine
fructus
azoospermia
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CN 200710099247
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CN 200710099247 priority Critical patent/CN101049475A/en
Publication of CN101049475A publication Critical patent/CN101049475A/en
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Abstract

A Chinese medicine for treating sterility caused by no sperm is prepared from more than 10 Chinese-medicinal materials including litchi kernel, tangerine kernel, astragalus root, burreed tuber, etc. Its advantages are sure curative effect, high safety, and no toxic by effect.

Description

A kind of Chinese medicine preparation for the treatment of azoospermia infertility
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of azoospermia infertility, is that a kind of azoospermia infertility for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Sexual intercourse has seminal fluid to penetrate, and smart amount is normal, through the person that all do not find the sperm of semen efamination more than 3 times, is called azoospermia.This disease is the common cause of male sterility, accounts for 19%~30% of male infertility.The azoospermia pathogenic factor is more, and two kinds of situations are arranged substantially: 1, spermatogenesis obstacle, and as congenital deformity of testis, anorchism, cryptorchidism, testis wound, tuberculosis of testis, the concurrent orchitis of mumps, vitamin poorness, edible Semen Gossypii wet goods for a long time.When hypothalamus or hypophysis cerebri endocrine dysfunction, can secondary cause hypoplasia of testis and cause dyszoospermia.As craniocerebral injury or intracranial tumour, make sperm can not discharge promoting sexual gland hormone and secrete androgen, can cause hypoplasia of testis, influence spermatogenesis.2, sperm is carried obstacle, as semen deposition pipeline deformity, congenital lack as, deferent duct wound, inflammation (epididymitis, epididymis, prostate, tuberculosis of seminal vesicle), ejaculatory duct obstruction etc.Above-mentioned reason can not be discharged sperm.The traditional Chinese medical science is thought that the formation of primary disease is many and is not filled because of congenital kidney qi, the natural endowment weakness, and essential substance for reproduction does not have the institute source; Or foster because of losing the day after tomorrow, to lose too, temper is strong, and liver blood does not fill, and essence and blood lacks the source; Also can be because of qi depression to blood stasis, venation is blocked, and smart road is obstructed; Or the testis wound, blood stasis is stagnated, and hinders smart road; Or careless by daily life, cold-damp, damp and hot heresy are gathered in testis, make smart blockage, can not overflow and rush down; Minority is because of mumps, the epidemic disease poison the moon of fainting of making a bet, and the acute orchitis and epididymitis residual poison influences spermatogenesis.Pathology character belongs to deficiency in origin and excess in superficiality, and pathogenesis is that essential substance for reproduction generates not enough and spermatic ejeculation obstacle two aspects.The traditional Chinese medical science is divided into deficiency of kidney-essence clinically, qi depression to blood stasis, and the stagnant heat stopband, the smart road of cold coagulation, disease type Coryza Treated by Syndrome Differentiation such as deficiency of qi and blood obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of azoospermia infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0~4 parts of 1.5~6 parts of Radix Astragali of 1.5~6 parts of Semen Citri Reticulataes of Semen Litchi
1.0~4 parts of 1.0~4 parts of Fructus Lycii of 0.1~2 part of rhizoma sparganic of Fructus Liquidambaris
1.0~4 parts of 1.0~4 portions of Radix Cyathulaes of 0.1~2 part of Rhizoma Curcumae of Colla Cornus Cervi
1.0~4 parts of 1.0~4 parts of Radix Paeoniae Rubra of 0.1~2 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 2.5~3.5 parts of Radix Astragali of 2.5~3.5 parts of Semen Citri Reticulataes of Semen Litchi
1.5~2.5 parts of 1.5~2.5 parts of Fructus Lycii of 0.5~1.5 part of rhizoma sparganic of Fructus Liquidambaris
1.5~2.5 parts of 1.5~2.5 portions of Radix Cyathulaes of 0.5~1.5 part of Rhizoma Curcumae of Colla Cornus Cervi
1.5~2.5 parts of 1.5~2.5 parts of Radix Paeoniae Rubra of 0.5~1.5 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 parts of Radix Astragali of 3 parts of Semen Citri Reticulataes of Semen Litchi
2 parts of 2 parts of Fructus Lycii of 1 part of rhizoma sparganic of Fructus Liquidambaris
2 parts of 2 portions of Radix Cyathulaes of 1 part of Rhizoma Curcumae of Colla Cornus Cervi
2 parts of 2 parts of Radix Paeoniae Rubra of 1 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Semen Litchi property of medicine, temperature.Return liver, kidney, stomach warp.Has regulating QI to relieve pain, the effect that cold relieving is loose and stagnated.Can treat colicky, painful and swollen testis, gastric abscess, dysmenorrhea and puerperal abdonimal pain etc.(the 2196th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine)
Semen Citri Reticulatae property of medicine hardship, flat.Return liver, kidney channel.Have and regulate the flow of vital energy, eliminating stagnation, analgesic effect.Can treat hernia, painful and swollen testis, acute mastitis, lumbago etc.(the 3745th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine)
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).
The Fructus Lycii property of medicine is sweet, flat.Return liver, kidney, lung meridian.Has nourishing the liver, nourishing kidney, the effect of lung moistening.Can treat caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, the taking fluids profusely etc. of quenching one's thirst.(the 2248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Liquidambaris property of medicine hardship, flat.Return liver, urinary bladder channel.Has dispelling, collateral-activating, the effect of diuretic dehumidifying.Can treat rheumatic arthralgia, wither muscle knot of limb, epigastric pain, amenorrhea, galactostasis, edema, eczema etc.(the 3470th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Colla Cornus Cervi property of medicine is salty, temperature.Return kidney, Liver Channel.Have the kidney warming, benefit is smart, bone and muscle strengthening, promoting the circulation of blood repercussive effect.Can treat the spinal column cold type of pain, sexual impotence, seminal emission, metrorrhagia, leukorrhagia, frequent micturition, carbuncle of yin nature skin infection, acute mastitis, traumatic injury congestive edema, bones and muscles pain etc.(the 3105th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Toosendan property of medicine hardship, cold, mild toxicity.Return liver, stomach, small intestine meridian.Have soothing the liver expelling the heat-evil, promoting the circulation of QI to relieve pain, parasiticidal effect.Can treat the gastral cavity abdomen pain over the hypochondriac region, hernia pain, abdominal pain due to worm stagnation, tinea capitis etc.(the 309th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine)
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Litchi and Semen Citri Reticulatae, is ministerial drug with Radix Astragali, rhizoma sparganic, Fructus Lycii, Rhizoma Curcumae, Radix Cyathulae, Radix Salviae Miltiorrhizae and Radix Paeoniae Rubra; With Fructus Liquidambaris, Colla Cornus Cervi and Fructus Toosendan is adjuvant.All medicines are harmonious, and are total to the tool depressed liver-energy dispersing and QI regulating, the effect of collateral dredging spermatogenesis.The treatment azoospermia infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment azoospermia infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat azoospermia infertility, and the prevention of azoospermia infertility is also had good effect, and the treatment azoospermia infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment azoospermia infertility; Treatment azoospermia infertility patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.9 examples of fully recovering account for 50%, and 8 examples that take a turn for the better account for 44.44%, and more 1 example does not account for 5.56%, and total effective rate reaches 94.44%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 3 parts of Radix Astragali of 3 parts of Semen Citri Reticulataes of Semen Litchi
2 parts of 2 parts of Fructus Lycii of 1 part of rhizoma sparganic of Fructus Liquidambaris
2 parts of 2 portions of Radix Cyathulaes of 1 part of Rhizoma Curcumae of Colla Cornus Cervi
2 parts of 2 parts of Radix Paeoniae Rubra of 1 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment azoospermia infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of azoospermia infertility is characterized in that it is made by the following weight proportion raw material:
1.0~4 parts of 1.5~6 parts of Radix Astragali of 1.5~6 parts of Semen Citri Reticulataes of Semen Litchi
1.0~4 parts of 1.0~4 parts of Fructus Lycii of 0.1~2 part of rhizoma sparganic of Fructus Liquidambaris
1.0~4 parts of 1.0~4 portions of Radix Cyathulaes of 0.1~2 part of Rhizoma Curcumae of Colla Cornus Cervi
1.0~4 parts of 1.0~4 parts of Radix Paeoniae Rubra of 0.1~2 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
2, a kind of Chinese medicine preparation for the treatment of azoospermia infertility according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 2.5~3.5 parts of Radix Astragali of 2.5~3.5 parts of Semen Citri Reticulataes of Semen Litchi
1.5~2.5 parts of 1.5~2.5 parts of Fructus Lycii of 0.5~1.5 part of rhizoma sparganic of Fructus Liquidambaris
1.5~2.5 parts of 1.5~2.5 portions of Radix Cyathulaes of 0.5~1.5 part of Rhizoma Curcumae of Colla Cornus Cervi
1.5~2.5 parts of 1.5~2.5 parts of Radix Paeoniae Rubra of 0.5~1.5 part of Radix Salviae Miltiorrhizae of Fructus Toosendan
3, a kind of Chinese medicine preparation for the treatment of azoospermia infertility according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 3 parts of Radix Astragali of 3 parts of Semen Citri Reticulataes of Semen Litchi
2 parts of 2 parts of Fructus Lycii of 1 part of rhizoma sparganic of Fructus Liquidambaris
2 parts of 2 portions of Radix Cyathulaes of 1 part of Rhizoma Curcumae of Colla Cornus Cervi
2 parts of 2 parts of Radix Paeoniae Rubra of 1 part of Radix Salviae Miltiorrhizae of Fructus Toosendan.
CN 200710099247 2007-05-16 2007-05-16 Preparation of Chinese traditional medicine for treating barrenness caused by no sperm Pending CN101049475A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520346A (en) * 2012-07-05 2014-01-22 国玺干细胞应用技术股份有限公司 Medicine composition for activating male sexual function

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520346A (en) * 2012-07-05 2014-01-22 国玺干细胞应用技术股份有限公司 Medicine composition for activating male sexual function
CN103520346B (en) * 2012-07-05 2015-11-18 国玺干细胞应用技术股份有限公司 Enliven the medical composition of male's sexual

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Open date: 20071010