CN101057903A - Traditional Chinese medicine preparation for curing acute eczema - Google Patents

Abstract

The invention relates to a traditional Chinese medicinal composition for treating acute eczema, which is prepared from more than ten kinds of Chinese medicinal herbs including Chinese angelica root, root of herbaceous peony, bupleurum root and poria cocos wolf.

Description

A kind of Chinese medicine preparation for the treatment of acute eczema

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of acute eczema, is that a kind of acute eczema for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Eczema is a kind of common inflammation dermatoses, and is many with the erythra form, is easy to ooze out, and the course of disease is delayed and tendency of recurrence is arranged is feature.Can be divided into acute, subacute and chronic three kinds of phases by its outbreak stage clinically.The infringement of acute eczema is a pleomorphism, conscious scorching hot and pruritus.With the passing of time acute inflammation alleviates or after treating, skin lesion drying, incrustation or squama, and enter subacute stage.The clinical manifestation of acute eczema is: erythra is most intensive big little pimple, papulovesicle or phlysises of foxtail millet grain, substrate flushing.Owing to scratch, after scratching brokenly, pimple, papulovesicle or vesicle top be that obvious point-like is oozed out and little rotten to the corn face, and serosity constantly oozes out, and the pathological changes center is often heavier, and spreads towards periphery gradually, and the periphery is dispersed in pimple, papulovesicle again, so indefinite border.When being associated with when infecting, then inflammation can be more obvious, and form pustule, and pus oozes out or ties yellow green or dirty brown crust.Also can merge folliculitis, furuncle, regional nodes's inflammation etc.Acute eczema can betide any position of body surface, and claim distributes more, be common in women's head-ornaments, ear after, distal limbs, hands, sufficient exposed division and scrotum, cysthus, anus etc. locate.Conscious acute pruritus.Drink, scratch, soap is washed, hot water scalds etc. that skin lesion is increased the weight of, gargalesthesia exacerbates, weight person influences sleep.

Acute eczema is commonly encountered diseases and the frequently-occurring disease in the dermatosis, because it shows effect repeatedly, does not heal year in year out, brings very big misery to the patient.Adopt the antihistaminic Drug therapy, curative effect is satisfactory inadequately.The corticosteroid hormone treatment has certain side effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of acute eczema.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Cortex Moutans of 1.5～6 parts of Poria of Radix Angelicae Sinensis

1.0～4 parts of 1.0～4 parts of Fructus Gardeniae (parched) of 1.5～6 parts of Radix Scutellariaes of the Radix Paeoniae Alba

1.0～4 parts of 1.0～4 portions of Flos Loniceraes of 1.5～6 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 0.1～2 part of Radix Astragali of Radix Saposhnikoviae

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts of 1.5～2.5 parts of Cortex Moutans of 2.5～3.5 parts of Poria of Radix Angelicae Sinensis

1.5～2.5 parts of 1.5～2.5 parts of Fructus Gardeniae (parched) of 2.5～3.5 parts of Radix Scutellariaes of the Radix Paeoniae Alba

1.5～2.5 parts of 1.5～2.5 portions of Flos Loniceraes of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 0.5～1.5 part of Radix Astragali of Radix Saposhnikoviae

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts of 2 parts of Cortex Moutans of 3 parts of Poria of Radix Angelicae Sinensis

2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Radix Scutellariaes of the Radix Paeoniae Alba

2 parts of 2 portions of Flos Loniceraes of 3 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Radix Astragali of Radix Saposhnikoviae

Drug action mechanism among the present invention is as follows:

The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).

Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Scutellariae nature and flavor hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Has heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.Can treat hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement etc.(the 248th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

Rhizoma Atractylodis Macrocephalae hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Flos Lonicerae property of medicine is sweet, and is cold.Attach to the lung and stomach meridians.Effect with heat-clearing and toxic substances removing.Can treat the heating of affection due to external wind and heat or epidemic febrile disease, heatstroke, toxic-heat and blood stasis, carbuncle furuncle, sore throat, multiple infectious disease etc.(the 1972nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Saposhnikoviae nature and flavor suffering, sweet, temperature.Return bladder, liver, spleen channel.Have inducing diaphoresis to dispel wind, win and wet, the effect of relieving convulsion.Can treat headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus etc.(the 117th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, the Radix Paeoniae Alba and Radix Bupleuri; With Poria, Radix Scutellariae, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Fructus Gardeniae (parched) and Flos Lonicerae is ministerial drug; With Radix Saposhnikoviae, the Radix Astragali and Radix Glycyrrhizae is adjuvant.All medicines are harmonious, altogether the effect of tool liver heat removing dampness removing.The treatment acute eczema has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment acute eczema of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat acute eczema, and the prevention of acute eczema is also had good effect, and the treatment acute eczema has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment acute eczema; Treatment acute eczema patient 24 examples, male's 14 examples, women's 10 examples, the age is 18～60 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.12 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 37.5%, and more 3 examples do not account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, the patient all has clear improvement or fully recovers.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts of 2 parts of Cortex Moutans of 3 parts of Poria of Radix Angelicae Sinensis

2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Radix Scutellariaes of the Radix Paeoniae Alba

2 parts of 2 portions of Flos Loniceraes of 3 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Radix Astragali of Radix Saposhnikoviae

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment acute eczema that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of acute eczema is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts of 1.0～4 parts of Cortex Moutans of 1.5～6 parts of Poria of Radix Angelicae Sinensis

1.0～4 parts of 1.0～4 parts of Fructus Gardeniae (parched) of 1.5～6 parts of Radix Scutellariaes of the Radix Paeoniae Alba

1.0～4 parts of 1.0～4 portions of Flos Loniceraes of 1.5～6 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 0.1～2 part of Radix Astragali of Radix Saposhnikoviae.

2, a kind of Chinese medicine preparation for the treatment of acute eczema according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts of 1.5～2.5 parts of Cortex Moutans of 2.5～3.5 parts of Poria of Radix Angelicae Sinensis

1.5～2.5 parts of 1.5～2.5 parts of Fructus Gardeniae (parched) of 2.5～3.5 parts of Radix Scutellariaes of the Radix Paeoniae Alba

1.5～2.5 parts of 1.5～2.5 portions of Flos Loniceraes of 2.5～3.5 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 0.5～1.5 part of Radix Astragali of Radix Saposhnikoviae.

3, a kind of Chinese medicine preparation for the treatment of acute eczema according to claim 1, wherein the weight proportion of each raw material is:

2 parts of 2 parts of Cortex Moutans of 3 parts of Poria of Radix Angelicae Sinensis

2 parts of 2 parts of Fructus Gardeniae (parched) of 3 parts of Radix Scutellariaes of the Radix Paeoniae Alba

2 parts of 2 portions of Flos Loniceraes of 3 parts of Rhizoma Atractylodis Macrocephalaes of Radix Bupleuri

1 part of 1 part of Radix Glycyrrhizae of 1 part of Radix Astragali of Radix Saposhnikoviae.