CN101066317A - Chinese medicine prepn for treating sterility caused by epididymitis - Google Patents

Abstract

The present invention provides Chinese medicine preparation for treating sterility caused by epididymitis. The Chinese medicine preparation is prepared with over ten kinds of Chinese medicinal materials, including litchi stone, selfheal, peach kernel, safflower, etc. It has the functions of benefiting qi, dispelling cold, regulating qi and activating collaterals. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine preparation has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

The Chinese medicine preparation of treatment epididymitis infertility

Technical field

The present invention relates to treat the Chinese medicine preparation of epididymitis infertility, is that the treatment epididymitis infertility is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Epididymitis is meant non-specific bacterial local infection, and its pathogenic bacterium see that with escherichia coli, staphylococcus streptococcus takes second place more, often involves testis.Bacteriology's data according to Melekos and one group of epididymitis case of Asbach (1987) shows that the bacterium that causes of the patient 56% more than 40 years old is a chlamydia trachomatis, and the infection of common urology department accounts for 22%; Patient's chlamydia trachomatis infection more than 40 years old only 18%, and the urinary tract bacterial infection accounts for 68%.Clinical minute acute epididymitis of primary disease and chronic epididymitis two classes.Acute epididymitis betides acute antibacterial and chlamydial infection.Chronic epididymitis is secondary to the mistake of acute stage more and controls wrong treatment, or exists simultaneously with chronic prostatitis.Age of onset was seen with blue or green, middle age more.Can be one-sided or bilateral fall ill simultaneously, bilateral is sent out the obturation of patient because of the epididymis tube chamber, can cause secondary infertility.Primary disease belongs to the category of the traditional Chinese medical science " acute orchitis and epididymitis ".Chinese medicine thinks that epididymitis is many because of the diseases caused by exogenous pathogenic factor cold-damp, blocks venation, the Liver Channel stagnation of QI; Or experience damp and hot heresy, pent up the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the liver failing to maintain the normal flow of QI; Or obstinate disease, qi depression to blood stasis and forming.It is wet that the traditional Chinese medical science is divided into the deficiency and coldness folder clinically, damp invasion of lower energizer, and disease type Coryza Treated by Syndrome Differentiation such as coagulation of QI-blood obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine preparation for the treatment of epididymitis infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts in 1.5～6 parts of Semen Persicaes of 1.5～6 parts of Semen Litchis of Semen Citri Reticulatae

1.0～4 parts of 1.0～4 parts of Cortex Magnoliae Officinalis of 1.0～4 parts of Spica Prunellaes of Flos Carthami

1.0～4 parts of 1.0～4 portions of Sargassums of 1.0～4 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

0.1～2 part of 0.1～2 part of Radix Bupleuri of 0.1～2 part of Fructus Foeniculi of Semen Vaccariae.

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts in 2.5～3.5 parts of Semen Persicaes of 2.5～3.5 parts of Semen Litchis of Semen Citri Reticulatae

1.5～2.5 parts of 1.5～2.5 parts of Cortex Magnoliae Officinalis of 1.5～2.5 parts of Spica Prunellaes of Flos Carthami

1.5～2.5 parts of 1.5～2.5 portions of Sargassums of 1.5～2.5 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

0.5～1.5 part of 0.5～1.5 part of Radix Bupleuri of 0.5～1.5 part of Fructus Foeniculi of Semen Vaccariae.

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts in 3 parts of Semen Persicaes of 3 parts of Semen Litchis of Semen Citri Reticulatae

2 parts of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Spica Prunellaes of Flos Carthami

2 parts of 2 portions of Sargassums of 2 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

1 part of 1 part of Radix Bupleuri of 1 part of Fructus Foeniculi of Semen Vaccariae.

Drug action mechanism among the present invention is as follows:

Semen Citri Reticulatae property of medicine hardship, flat.Return liver, kidney channel.Have and regulate the flow of vital energy, eliminating stagnation, analgesic effect.Can treat hernia, painful and swollen testis, acute mastitis, lumbago etc.(the 3745th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Semen Litchi property of medicine, temperature.Return liver, kidney, stomach warp.Has regulating QI to relieve pain, the effect that cold relieving is loose and stagnated.Can treat colicky, painful and swollen testis, gastric abscess, dysmenorrhea and puerperal abdonimal pain etc.(the 2196th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine)

Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Spica Prunellae property of medicine hardship, suffering, cold.Return liver, gallbladder meridian.Has liver heat removing and eyesight improving, the effect of powder detoxifcation.Can treat the conjunctival congestion photophobia, ophthalmalgia, it is dizzy to have a headache, tinnitus, scrofula goiter, acute mastitis mumps, carbuncle furuncle and phyma poison, acute and chronic hepatitis, hypertension etc.(the 2562nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Magnoliae Officinalis property of medicine hardship, suffering, temperature.Return stomach, large intestine channel.Has the circulation of qi promoting intestinal stasis relieving, dampness, the effect of lowering the adverse QI to relieve asthma.Can treat stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough etc.(the 2284th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Thallus Laminariae (Thallus Eckloniae) property of medicine is salty, and is cold.Return liver, stomach, kidney channel.Has softening and eliminating sputum, the effect of inducing diuresis to remove edema.Can treat goiter, scrofula, dysphagic, beriberi edema etc.(the 1887th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Sargassum property of medicine is salty, and is cold.Return liver, stomach, kidney channel.Has eliminating phlegm and softening indurated mass, the effect of diuretic detumescent.Can treat goiter, scrofula, beriberi edema etc.(the 2737th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Semen Vaccariae property of medicine hardship, flat.Return liver, stomach warp.Has promoting blood circulation to restore menstrual flow, the effect of stimulating milk secretion eliminating carbuncle.Can treat women's abdominal pain during menstruation, amenorrhea, galactostasis, acute mastitis, carbuncle etc.(the 426th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Foeniculi property of medicine suffering, temperature.Return liver, kidney, bladder, stomach warp.Has the warm liver of the kidney warming, promoting the circulation of QI to relieve pain, the effect of stomach function regulating.Can treat colic of cold type stomachache, the testis swelling and hanging down of either of the testes, coldness and pain in the epigastrium, lack of appetite and vomiting, hypochondriac pain, lumbago due to renal deficiency, dysmenorrhea etc.(the 348th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Citri Reticulatae and Semen Litchi, is ministerial drug with Semen Persicae, Flos Carthami, Spica Prunellae, Cortex Magnoliae Officinalis, Thallus Laminariae (Thallus Eckloniae), Radix Astragali and Sargassum; With Semen Vaccariae, Fructus Foeniculi and Radix Bupleuri is adjuvant.All medicines are harmonious, and are total to tool QI invigorating cold expelling, the effect of regulating QI to activate collateral.The treatment epididymitis infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment epididymitis infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat epididymitis infertility, and the prevention of epididymitis infertility is also had good effect, and the treatment epididymitis infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment epididymitis infertility; Treatment epididymitis infertility patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.9 examples of fully recovering account for 50%, and 7 examples that take a turn for the better account for 38.89%, and more 2 examples do not account for 11.11%, and total effective rate reaches 88.89%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts in 3 parts of Semen Persicaes of 3 parts of Semen Litchis of Semen Citri Reticulatae

2 parts of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Spica Prunellaes of Flos Carthami

2 parts of 2 portions of Sargassums of 2 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

1 part of 1 part of Radix Bupleuri of 1 part of Fructus Foeniculi of Semen Vaccariae.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment epididymitis infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, the Chinese medicine preparation of treatment epididymitis infertility is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts in 1.5～6 parts of Semen Persicaes of 1.5～6 parts of Semen Litchis of Semen Citri Reticulatae

1.0～4 parts of 1.0～4 parts of Cortex Magnoliae Officinalis of 1.0～4 parts of Spica Prunellaes of Flos Carthami

1.0～4 parts of 1.0～4 portions of Sargassums of 1.0～4 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

0.1～2 part of 0.1～2 part of Radix Bupleuri of 0.1～2 part of Fructus Foeniculi of Semen Vaccariae.

2, the Chinese medicine preparation of treatment epididymitis infertility according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts in 2.5～3.5 parts of Semen Persicaes of 2.5～3.5 parts of Semen Litchis of Semen Citri Reticulatae

1.5～2.5 parts of 1.5～2.5 parts of Cortex Magnoliae Officinalis of 1.5～2.5 parts of Spica Prunellaes of Flos Carthami

1.5～2.5 parts of 1.5～2.5 portions of Sargassums of 1.5～2.5 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

0.5～1.5 part of 0.5～1.5 part of Radix Bupleuri of 0.5～1.5 part of Fructus Foeniculi of Semen Vaccariae.

3, the Chinese medicine preparation of treatment epididymitis infertility according to claim 1, wherein the weight proportion of each raw material is:

2 parts in 3 parts of Semen Persicaes of 3 parts of Semen Litchis of Semen Citri Reticulatae

2 parts of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Spica Prunellaes of Flos Carthami

2 parts of 2 portions of Sargassums of 2 parts of Radix Astragali of Thallus Laminariae (Thallus Eckloniae)

1 part of 1 part of Radix Bupleuri of 1 part of Fructus Foeniculi of Semen Vaccariae.