CN101049404A - Preparation of Chinese traditional medicine for treating barrenness caused by obstruction of ovulation - Google Patents

Preparation of Chinese traditional medicine for treating barrenness caused by obstruction of ovulation Download PDF

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Publication number
CN101049404A
CN101049404A CN 200710099256 CN200710099256A CN101049404A CN 101049404 A CN101049404 A CN 101049404A CN 200710099256 CN200710099256 CN 200710099256 CN 200710099256 A CN200710099256 A CN 200710099256A CN 101049404 A CN101049404 A CN 101049404A
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parts
radix
chinese medicine
fructus
portions
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

A Chinese medicine for treating the acyesis caused by ovulatory obstacle is prepared from more than 10 Chinese-medicinal materials including astragalus root, Chinese angelica root, rehmannia root, pilose asiabell root, etc. Its advantages are sure curative effect, high safety, and no toxic by effect.

Description

A kind of Chinese medicine preparation for the treatment of ovulation failure infertility
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of ovulation failure infertility, is that a kind of ovulation failure infertility for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Influence ovulation function for some reason and ovary fails to ovulate is called ovulation failure.Ovulation failure is discharged because of no ovum, thus cause infertile, be female acyesis commonly encountered diseases because of, account for about 20%.The cause of disease that causes ovulation failure is a lot, and wherein important factor has: 1. Nervous and Mental Factors: women's emotion is anxiety, anxiety, melancholy too, environment amenorrhea, anorexia nervosa.2. autonomic nervous dysfunction.3. hyperthyroidism or go down, adrenal cortex function is hyperfunction or go down.4. malnutrition and Chronic consumptions: as serious anemia, avitaminosis.5. hypothalamus disease: birth defect, wound is poisoned, and infects tumor, hyperprolactinemia.6. chromosomal abnormality.7. hypophysis disease: birth defect, empty sella syndrome, hypopituitarism, pituitary tumor.8. ovarian disease: birth defect, premature ovarian failure, ovarian tumor, polycystic ovarian syndrome etc.The traditional Chinese medical science thinks that anovular reason is an insufficiency of kidney-YANG, decline of the fire from the gate of life.Because kidney governing reproduction, kidney to brain, dash appoint, the control of functions such as menses, uterus and regulate not normal then infertile.The traditional Chinese medical science is divided into the deficiency of vital energy clinically, blood deficiency, and the stagnation of QI, blood stasis, kidney yang is lost empty, the hepatic and renal YIN deficiency, disease type Coryza Treated by Syndrome Differentiation such as stagnation of phlegm-damp obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of ovulation failure infertility.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Rehmanniae of 1.5~6 parts of Radix Angelicae Sinensis of Radix Astragali
0.1~2 part of 1.0~4 parts of Fructus Corni of 1.0~4 parts of Radix Codonopsis of Radix Cyathulae
0.1~2 part of 1.0~4 parts of Cherokee rose of 1.0~4 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
0.1~2 part of 1.0~4 parts of Fructus Schisandrae Chinensis of 1.0~4 portions of Rhizoma Dioscoreaes of Herba Ecliptae
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Rehmanniae of 2.5~3.5 parts of Radix Angelicae Sinensis of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Fructus Corni of 1.5~2.5 parts of Radix Codonopsis of Radix Cyathulae
0.5~1.5 part of 1.5~2.5 parts of Cherokee rose of 1.5~2.5 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
0.5~1.5 part of 1.5~2.5 parts of Fructus Schisandrae Chinensis of 1.5~2.5 portions of Rhizoma Dioscoreaes of Herba Ecliptae
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radix Rehmanniae of 3 parts of Radix Angelicae Sinensis of Radix Astragali
1 part of 2 parts of Fructus Corni of 2 parts of Radix Codonopsis of Radix Cyathulae
1 part of 2 parts of Cherokee rose of 2 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
1 part of 2 parts of Fructus Schisandrae Chinensis of 2 portions of Rhizoma Dioscoreaes of Herba Ecliptae
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Rosae Laevigatae property of medicine acid, puckery, flat.Return spleen, kidney, urinary bladder channel.Has controlling nocturnal emission with astringent drugs, reducing urination, astringing intestine to stop diarrhea, the effect of leukorrhagia stopping.Can treat seminal emission, spermatorrhea, the enuresis, frequent micturition, chronic diarrhea, chronic dysentery, nebulousurine, leukorrhagia, metrorrhagia etc.(the 1976th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Schisandrae Chinensis property of medicine, warm in nature.Return lung, the heart, kidney channel.It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, the effect of mind tranquilizing and the heart calming.Can treat the chronic cough dyspnea due to deficiency, emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia etc.(the 520th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Astragali, Radix Angelicae Sinensis and Radix Rehmanniae, is ministerial drug with Radix Cyathulae, Radix Codonopsis, Fructus Ligustri Lucidi, the Radix Paeoniae Alba, Herba Ecliptae and Rhizoma Dioscoreae; With Fructus Corni, Cherokee rose and Fructus Schisandrae Chinensis is adjuvant.All medicines are harmonious, and are total to the tool benefiting QI and nourishing blood, the effect of tonifying the kidney to consolidate the essence.The treatment ovulation failure infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment ovulation failure infertility of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat ovulation failure infertility, and the prevention of ovulation failure infertility is also had good effect, and the treatment ovulation failure infertility has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment ovulation failure infertility; Treatment ovulation failure infertility patient 24 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.12 examples of fully recovering account for 50%, and 10 examples that take a turn for the better account for 41.67%, and more 2 examples do not account for 8.33%, and total effective rate reaches 91.67%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Rehmanniae of 3 parts of Radix Angelicae Sinensis of Radix Astragali
1 part of 2 parts of Fructus Corni of 2 parts of Radix Codonopsis of Radix Cyathulae
1 part of 2 parts of Cherokee rose of 2 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
1 part of 2 parts of Fructus Schisandrae Chinensis of 2 portions of Rhizoma Dioscoreaes of Herba Ecliptae
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment ovulation failure infertility that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of ovulation failure infertility is characterized in that it is made by the following weight proportion raw material:
1.5~6 parts of 1.5~6 parts of Radix Rehmanniae of 1.5~6 parts of Radix Angelicae Sinensis of Radix Astragali
0.1~2 part of 1.0~4 parts of Fructus Corni of 1.0~4 parts of Radix Codonopsis of Radix Cyathulae
0.1~2 part of 1.0~4 parts of Cherokee rose of 1.0~4 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
0.1~2 part of 1.0~4 parts of Fructus Schisandrae Chinensis of 1.0~4 portions of Rhizoma Dioscoreaes of Herba Ecliptae
2, a kind of Chinese medicine preparation for the treatment of ovulation failure infertility according to claim 1, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of Radix Rehmanniae of 2.5~3.5 parts of Radix Angelicae Sinensis of Radix Astragali
0.5~1.5 part of 1.5~2.5 parts of Fructus Corni of 1.5~2.5 parts of Radix Codonopsis of Radix Cyathulae
0.5~1.5 part of 1.5~2.5 parts of Cherokee rose of 1.5~2.5 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
0.5~1.5 part of 1.5~2.5 parts of Fructus Schisandrae Chinensis of 1.5~2.5 portions of Rhizoma Dioscoreaes of Herba Ecliptae
3, a kind of Chinese medicine preparation for the treatment of ovulation failure infertility according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radix Rehmanniae of 3 parts of Radix Angelicae Sinensis of Radix Astragali
1 part of 2 parts of Fructus Corni of 2 parts of Radix Codonopsis of Radix Cyathulae
1 part of 2 parts of Cherokee rose of 2 portions of Radix Paeoniae Albas of Fructus Ligustri Lucidi
1 part of 2 parts of Fructus Schisandrae Chinensis of 2 portions of Rhizoma Dioscoreaes of Herba Ecliptae
CN 200710099256 2007-05-16 2007-05-16 Preparation of Chinese traditional medicine for treating barrenness caused by obstruction of ovulation Pending CN101049404A (en)

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Application Number Priority Date Filing Date Title
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CN101049404A true CN101049404A (en) 2007-10-10

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895353A (en) * 2012-11-09 2013-01-30 张洪涛 Chinese herbal medicine for treating cow luteinization dyspoiesis
CN113318172A (en) * 2021-06-17 2021-08-31 马倩雯 Traditional Chinese medicine composition for treating ovarian reserve function decline combined infertility and preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102895353A (en) * 2012-11-09 2013-01-30 张洪涛 Chinese herbal medicine for treating cow luteinization dyspoiesis
CN113318172A (en) * 2021-06-17 2021-08-31 马倩雯 Traditional Chinese medicine composition for treating ovarian reserve function decline combined infertility and preparation method and application thereof

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Open date: 20071010