CN101019561A - Air germicide for antagonizing epidemic encephalitis and influenza viruses - Google Patents

Air germicide for antagonizing epidemic encephalitis and influenza viruses Download PDF

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Publication number
CN101019561A
CN101019561A CN 200710067573 CN200710067573A CN101019561A CN 101019561 A CN101019561 A CN 101019561A CN 200710067573 CN200710067573 CN 200710067573 CN 200710067573 A CN200710067573 A CN 200710067573A CN 101019561 A CN101019561 A CN 101019561A
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gram
grams
root
influenza virus
raw material
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CN 200710067573
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郑泰林
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Abstract

The air germicide for antagonizing epidemic encephalitis and influenza viruses is prepared with storax, benzoin, basket kern, capillary Artemisia, eupatorium and other eight kinds of Chinese medicinal materials in certain weight proportion. The preparation process includes the following steps: 1. soaking the materials, decocting and filtering to obtain medicine liquid; 2. concentrating the medicine liquid, cooling, adding alcohol to precipitate, filtering to obtain the filtrate, adding eucalyptus oil in the same weight to the filtrate, reacting and precipitating for 1 day; and 3. adding clove oil in 5 wt%. The present invention has obvious effect of preventing influenza and other upper respiratory tract infection diseases, and is volatized through heating or naturally.

Description

The air disinfection agent of a kind of anti-current brain influenza virus
Technical field
The present invention relates to a kind of bactericide, mainly is the air disinfection agent of a kind of anti-current brain influenza virus.
Background technology
At present, the air disinfection agent is of a great variety, but all is not formulated by pure Chinese medicine.The bactericidal effect that has is good but toxicity is also big, in sterilization human body has also been caused great injury; There are not bactericidal effect or DeGrain but the toxicity that has is less relatively at all.
Summary of the invention
The objective of the invention is in order to overcome above-mentioned deficiency, and provide a kind of bactericidal effect good, the air disinfection agent of avirulent anti-current brain influenza virus.
The technical solution adopted for the present invention to solve the technical problems.The air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 1-10 gram, styrax 1-10 gram, rhizome of cyrtomium 1-10 gram, oriental wormwood 1-10 gram, eupatorium 1-10 gram, root of Dahurain angelica 1-10 gram, rhizoma atractylodis 1-10 gram, coptis 1-10 gram, root of large-flowered skullcap 1-10 gram, rose 1-10 gram, Centipeda minima 1-40 gram, bright folium eucalypti 1-40 gram, cloves 1-10 gram.
The present invention can increase following raw material in above-mentioned prescription, its weight proportion is: folium isatidis 10-20 gram, isatis root 10-20 gram, climbing groundsel 10-20 gram, honeysuckle flower 10-20 gram, Herba Andrographitis 10-20 gram, rhizoma dioscoreae nipponicae 10-20 gram, geranium wilfordii 10-20 gram, clean loguat leaf 10-20 gram.
The production method of the air disinfection agent of this resisiting influenza virus of the present invention, its step is as follows:
1), raw material soaks, and decocts one hour, filtration takes concoction;
2), concentrate and to add alcohol precipitation half a day after the cooling, filter then, the juice after the filtration added eucalyptus oil by weight 1: 1, fully reacted postprecipitation one day;
3), on weight of solution 5% with caryophyllus oil, promptly finish whole product.
The effect that the present invention is useful is: the present invention is formed by multiple rare Chinese medicine (cloves etc.) and solvent alcoholic extraction.Pathogenic microorganisms such as epidemic meningitis influenza virus, staphylococcus aureus there are obvious suppression and killing action.Being mainly used in illnesss such as preventing and treating influenza, the infection of the upper respiratory tract has a significant effect.With this agent heated volatile or spraying, or drip and on amenities, to allow it volatilize naturally during use.
Embodiment:
Below in conjunction with drawings and Examples the present invention is further described.
Embodiment 1: the air disinfection agent of this anti-current brain influenza virus, mainly make: storax 1 gram, styrax 2 grams by the combination of following weight proportion raw material, rhizome of cyrtomium 2 grams, oriental wormwood 3 grams, eupatorium 5 grams, the root of Dahurain angelica 4 grams, rhizoma atractylodis 2 grams, the coptis 5 grams, the root of large-flowered skullcap 6 grams, rose 2 grams, Centipeda minima 1 gram, bright folium eucalypti 1 gram, cloves 5 grams.
The production method of the air disinfection agent of this resisiting influenza virus of the present invention, its step is as follows:
1), raw material soaks, and decocts one hour, filtration takes concoction;
2), concentrate and to add alcohol precipitation half a day after the cooling, filter then, the juice after the filtration added eucalyptus oil by weight 1: 1, fully reacted postprecipitation one day;
3), on weight of solution 5% with caryophyllus oil, promptly finish whole product.
Embodiment 2: be that with the difference of embodiment 1 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 2 grams, styrax 3 grams, rhizome of cyrtomium 5 grams, oriental wormwood 6 grams, eupatorium 10 grams, the root of Dahurain angelica 7 grams, rhizoma atractylodis 8 grams, the coptis 4 grams, the root of large-flowered skullcap 6 grams, rose 5 grams, Centipeda minima 7 grams, bright folium eucalypti 3 grams, cloves 8 grams.
Embodiment 3: be that with the difference of embodiment 1 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 5 grams, styrax 4 grams, rhizome of cyrtomium 3 grams, oriental wormwood 7 grams, eupatorium 8 grams, the root of Dahurain angelica 3 grams, rhizoma atractylodis 4 grams, the coptis 3 grams, the root of large-flowered skullcap 8 grams, rose 4 grams, Centipeda minima 5 grams, bright folium eucalypti 6 grams, cloves 9 grams.
Embodiment 4: be that with the difference of embodiment 1 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 5 grams, styrax 6 grams, rhizome of cyrtomium 7 grams, oriental wormwood 5 grams, eupatorium 5 grams, the root of Dahurain angelica 4 grams, rhizoma atractylodis 3 grams, the coptis 8 grams, the root of large-flowered skullcap 5 grams, rose 2 grams, Centipeda minima 6 grams, bright folium eucalypti 5 grams, cloves 4 grams.
Embodiment 5: be that with the difference of embodiment 1 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 8 grams, styrax 6 grams, rhizome of cyrtomium 4 grams, oriental wormwood 7 grams, eupatorium 2 grams, the root of Dahurain angelica 6 grams, rhizoma atractylodis 3 grams, the coptis 7 grams, the root of large-flowered skullcap 2 grams, rose 6 grams, Centipeda minima 4 grams, bright folium eucalypti 3 grams, cloves 6 grams.
Embodiment 6: be that with the difference of embodiment 1 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 6 grams, styrax 5 grams, rhizome of cyrtomium 4 grams, oriental wormwood 2 grams, eupatorium 6 grams, the root of Dahurain angelica 3 grams, rhizoma atractylodis 6 grams, the coptis 7 grams, the root of large-flowered skullcap 4 grams, rose 2 grams, Centipeda minima 8 grams, bright folium eucalypti 9 grams, cloves 6 grams, folium isatidis 15 grams, isatis root 10 grams, climbing groundsel 12 grams, honeysuckle flower 14 grams, Herba Andrographitis 15 grams, rhizoma dioscoreae nipponicae 16 grams, geranium wilfordii 14 grams, clean loguat leaf 12 grams.
Embodiment 7: be that with the difference of embodiment 6 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 4 grams, styrax 2 grams, rhizome of cyrtomium 6 grams, oriental wormwood 8 grams, eupatorium 6 grams, the root of Dahurain angelica 4 grams, rhizoma atractylodis 2 grams, the coptis 3, the root of large-flowered skullcap 5 grams, rose 7 grams, Centipeda minima 9 grams, bright folium eucalypti 7 grams, cloves 5 grams, folium isatidis 13 grams, isatis root 16 grams, climbing groundsel 10 grams, honeysuckle flower 12 grams, Herba Andrographitis 15 grams, rhizoma dioscoreae nipponicae 18 grams, geranium wilfordii 14 grams, clean loguat leaf 12 grams.
Embodiment 8: be that with the difference of embodiment 6 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 6 grams, styrax 2 grams, rhizome of cyrtomium 3 grams, oriental wormwood 5 grams, eupatorium 7 grams, the root of Dahurain angelica 6 grams, rhizoma atractylodis 8 grams, the coptis 3 grams, the root of large-flowered skullcap 2 grams, rose 7 grams, Centipeda minima 9 grams, bright folium eucalypti 8 grams, cloves 6 grams, folium isatidis 12 grams, isatis root 14 grams, climbing groundsel 16 grams, honeysuckle flower 18 grams, Herba Andrographitis 20 grams, rhizoma dioscoreae nipponicae 10 grams, geranium wilfordii 10 grams, clean loguat leaf 16 grams.
Embodiment 9: be that with the difference of embodiment 6 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 1 gram, styrax 3 grams, rhizome of cyrtomium 5 grams, oriental wormwood 10 grams, eupatorium 4 grams, the root of Dahurain angelica 5 grams, rhizoma atractylodis 6 grams, the coptis 5 grams, the root of large-flowered skullcap 4 grams, rose 8 grams, Centipeda minima 3 grams, bright folium eucalypti 4 grams, cloves 6 grams, folium isatidis 16 grams, isatis root 14 grams, climbing groundsel 12 grams, honeysuckle flower 20 grams, Herba Andrographitis 10 grams, rhizoma dioscoreae nipponicae 15 grams, geranium wilfordii 18 grams, clean loguat leaf 15 grams.
Embodiment 10: be that with the difference of embodiment 6 proportion of raw materials is different, the air disinfection agent of this anti-current brain influenza virus is mainly made by the combination of following weight proportion raw material: storax 10 grams, styrax 2 grams, rhizome of cyrtomium 5 grams, oriental wormwood 7 grams, eupatorium 8 grams, the root of Dahurain angelica 6 grams, rhizoma atractylodis 4 grams, the coptis 6 grams, the root of large-flowered skullcap 2 grams, rose 8 grams, Centipeda minima 6 grams, bright folium eucalypti 3 grams, cloves 5 grams, folium isatidis 15 grams, isatis root 12 grams, climbing groundsel 18 grams, honeysuckle flower 14 grams, Herba Andrographitis 20 grams, rhizoma dioscoreae nipponicae 10 grams, geranium wilfordii 12 grams, clean loguat leaf 15 grams.
Bactericidal effect experiment of the present invention:
1, experimental strain: meningococcus (Neisseria meningitidis) ATCC29019, beta hemolytic streptococcus (local strain), natural bacteria amounts to three kinds
2, method: adopting the supporting use of PTC heater element heater (surface moisture 150+/-20 ℃), is a slice (containing former medicine 2ml) 15 square metres of room innerlich anwenden amounts, observes the stifling bactericidal effect of different time.
The result:
1, to the killing effect of natural bacteria, the natural bacteria amount is 1092/cubic metre before being about 15 square metres of indoor sterilizations, and the fumigation time is when being 30,60,90 minutes, and the sterilizing rate of spontaneous combustion bacterium is respectively 71.89%, 94.32%, 95.70%.
2, to meningococcus, beta hemolytic streptococcus killing effect, employing support methods, the fumigation time is 30,60,90 minutes, observe different time meningococcus and beta hemolytic streptococcus killing effect are respectively 96.71%, 98.42%, 99.94%, 50.00%, 68.00%, 87.20%, contrast bacterium amount is respectively 8.2 * 10 6, 5.0 * 10 6
Acute toxicity experience of the present invention:
One: material and method
Specimen: sample is fallow transparency liquid, has peat-reek, and is volatile, about PH=.
Laboratory animal: buy the NIH kind mouse that grows up, male and female half and half from the Zhejiang Medical university Experimental Animal Center.
Method: with reference to static contamination method.Press 100g/m 3, the spraying volatilization, mouse places 0.75M 3Toxicant exposure cabinet in, suck contamination 2 hours, take out the back and observe a week, the record toxic reaction.
Two, result and discussion
Excited symptom appears in experiment contamination animal half an hour, and is vivaciously active, engenders the inhibition symptom thereafter, and the animal peace and quiet are motionless, and exaggerated respiration is drowsiness, until contamination 2 hours, takes out.Animal recovers as usual after 24 hours, continues to observe a week again, does not change.Suck Lc50 greater than 100g/m so record mouse 3, according to the acute toxicity grading criteria of Deichmann and gerarde (1969), it is nontoxic substantially that sample belongs to.

Claims (3)

1, the air disinfection agent of a kind of anti-current brain influenza virus is characterized in that: mainly made by the combination of following weight proportion raw material: storax 1-10 gram, styrax 1-10 gram, rhizome of cyrtomium 1-10 gram, oriental wormwood 1-10 gram, eupatorium 1-10 gram, root of Dahurain angelica 1-10 gram, rhizoma atractylodis 1-10 gram, coptis 1-10 gram, root of large-flowered skullcap 1-10 gram, rose 1-10 gram, Centipeda minima 1-40 gram, bright folium eucalypti 1-40 gram, cloves 1-10 gram.
2, the air disinfection agent of anti-current brain influenza virus according to claim 1, it is characterized in that: increase following raw material, its weight proportion is: folium isatidis 10-20 gram, isatis root 10-20 gram, climbing groundsel 10-20 gram, honeysuckle flower 10-20 gram, Herba Andrographitis 10-20 gram, rhizoma dioscoreae nipponicae 10-20 gram, geranium wilfordii 10-20 gram, clean loguat leaf 10-20 gram.
3, the production method of the air disinfection agent of a kind of anti-current brain influenza virus, it is characterized in that: its step is as follows:
1), raw material soaks, and decocts one hour, filtration takes concoction;
2), concentrate and to add alcohol precipitation half a day after the cooling, filter then, the juice after the filtration added eucalyptus oil by weight 1: 1, fully reacted postprecipitation one day;
3), on weight of solution 5% with caryophyllus oil, promptly finish whole product.
CN 200710067573 2007-03-14 2007-03-14 Air germicide for antagonizing epidemic encephalitis and influenza viruses Pending CN101019561A (en)

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Application Number Priority Date Filing Date Title
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461385A (en) * 2007-12-20 2009-06-24 天津仁怡生物工程技术有限公司 Bacteriostat of gram positive bacteria and gram negative bacteria and use thereof
CN102326699A (en) * 2011-07-29 2012-01-25 颍上县润海畜禽养殖有限公司 Grass fragrance goose feed and preparation method thereof
CN103430976A (en) * 2013-09-12 2013-12-11 周洪亮 Spray for disinfection of prenatal screening diagnosis center
CN101461558B (en) * 2007-12-20 2014-05-07 天津仁怡生物工程技术有限公司 Aspergillus bacteriostatic agent and use thereof
CN112471178A (en) * 2020-11-03 2021-03-12 雁知堂中医药科技(山西)有限责任公司 Traditional Chinese medicine incense formula for avoiding plague and preventing epidemic

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461385A (en) * 2007-12-20 2009-06-24 天津仁怡生物工程技术有限公司 Bacteriostat of gram positive bacteria and gram negative bacteria and use thereof
CN101461558B (en) * 2007-12-20 2014-05-07 天津仁怡生物工程技术有限公司 Aspergillus bacteriostatic agent and use thereof
CN101461385B (en) * 2007-12-20 2014-11-05 天津仁怡生物工程技术有限公司 Bacteriostat of gram positive bacteria and gram negative bacteria and use thereof
CN102326699A (en) * 2011-07-29 2012-01-25 颍上县润海畜禽养殖有限公司 Grass fragrance goose feed and preparation method thereof
CN102326699B (en) * 2011-07-29 2012-12-26 颍上县润海畜禽养殖有限公司 Grass fragrance goose feed and preparation method thereof
CN103430976A (en) * 2013-09-12 2013-12-11 周洪亮 Spray for disinfection of prenatal screening diagnosis center
CN103430976B (en) * 2013-09-12 2015-06-17 周洪亮 Spray for disinfection of prenatal screening diagnosis center
CN112471178A (en) * 2020-11-03 2021-03-12 雁知堂中医药科技(山西)有限责任公司 Traditional Chinese medicine incense formula for avoiding plague and preventing epidemic

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