CN101003800A - 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 - Google Patents
使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8771—Bovine embryos
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- A—HUMAN NECESSITIES
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- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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- A—HUMAN NECESSITIES
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- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/02—Cells from transgenic animals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer
Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US88828397A | 1997-07-03 | 1997-07-03 | |
| US08/888,283 | 1997-07-03 |
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| CN98807691A Division CN1265599A (zh) | 1997-07-03 | 1998-06-24 | 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 |
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| CN101003800A true CN101003800A (zh) | 2007-07-25 |
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| CNA2007100081920A Pending CN101003800A (zh) | 1997-07-03 | 1998-06-24 | 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 |
| CN98807691A Pending CN1265599A (zh) | 1997-07-03 | 1998-06-24 | 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 |
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| CN98807691A Pending CN1265599A (zh) | 1997-07-03 | 1998-06-24 | 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆 |
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| Country | Link |
|---|---|
| EP (1) | EP1017422A4 (https=) |
| JP (1) | JP2001509361A (https=) |
| CN (2) | CN101003800A (https=) |
| AU (1) | AU8154398A (https=) |
| BR (1) | BR9811657A (https=) |
| CA (1) | CA2294916A1 (https=) |
| IL (1) | IL133786A0 (https=) |
| NZ (1) | NZ502129A (https=) |
| WO (1) | WO1999001163A1 (https=) |
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| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| RU2216592C2 (ru) * | 1998-01-16 | 2003-11-20 | Агробиоген Гмбх | Способ получения эмбрионов животных и способ выращивания животного из эмбрионов |
| US6331659B1 (en) | 1998-01-21 | 2001-12-18 | University Of Hawaii | Cumulus cells as nuclear donors |
| CA2324009A1 (en) * | 1998-03-16 | 1999-09-23 | Relag Pty Ltd. | Porcine nuclear transfer |
| AUPP294898A0 (en) * | 1998-04-15 | 1998-05-07 | Monash University | Method of nuclear transfer |
| US6781030B1 (en) | 1998-11-02 | 2004-08-24 | Trustee Of Tufts College, Ballou Hall | Methods for cloning mammals using telophase oocytes |
| WO2000025578A2 (en) * | 1999-04-26 | 2000-05-11 | Trustees Of Tufts College | Methods for cloning animals |
| EP1818397A1 (en) * | 1998-11-02 | 2007-08-15 | Trustees Of Tufts College | Methods for cloning animals |
| EP1375654A3 (en) * | 1998-11-02 | 2008-01-16 | GTC Biotherapeutics, Inc. | Transgenic and cloned mammals |
| DK1159415T3 (da) | 1999-03-04 | 2010-05-03 | Revivicor Inc | Genetisk modifikation af somatiske celler og anvendelse deraf |
| AU5577600A (en) * | 1999-06-30 | 2001-01-31 | Woo-Suk Hwang | A method for producing human embryonic skin cells by employing an inter-species nuclear transplantation technique |
| WO2001000795A1 (en) * | 1999-06-30 | 2001-01-04 | Hwang, Woo-Suk | A method for producing cloned cows |
| AU753209B2 (en) * | 1999-06-30 | 2002-10-10 | Seoul National University Industry Foundation | Method for producing cloned tigers by employing inter-species nuclear transplantation technique |
| WO2001029206A1 (en) | 1999-10-15 | 2001-04-26 | Advanced Cell Technology, Inc. | Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells |
| GB2380202A (en) * | 2000-06-08 | 2003-04-02 | Trostner Jens | Method for the genetic reconstruction of human organs |
| EA013564B1 (ru) | 2000-08-03 | 2010-06-30 | Терапеутик Хьюман Поликлоналз Инк. | Гуманизированный иммуноглобулин и содержащая его фармацевтическая композиция |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| AU2001297880B2 (en) * | 2000-11-30 | 2007-05-31 | Stemron Inc. | Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same |
| DE60144248D1 (de) * | 2000-12-22 | 2011-04-28 | Kyowa Hakko Kirin Co Ltd | Verfahren zur klonierung von nichtmenschliche säugern unter verwendung von reprogrammiertem donorchromatin oder donorzellen |
| ATE466089T1 (de) | 2000-12-22 | 2010-05-15 | Agronomique Inst Nat Rech | Positionsunabhängige und gewebespezifische expression eines transgens in der milch eines transgen-tieres |
| BR0211895A (pt) | 2001-08-13 | 2006-04-04 | Embrex Inc | métodos de injetar um ovo avìcola, injetar uma pluralidade de ovos avìculas, de produzir uma ave quimérica e uma ave transgênica |
| US20030204860A1 (en) * | 2002-04-01 | 2003-10-30 | David Melican | Method for selecting cell lines to be used for nuclear transfer in mammalian species |
| US7612250B2 (en) | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
| RU2308281C1 (ru) * | 2006-04-05 | 2007-10-20 | ГУ Научно-исследовательский институт фармакологии Томского научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ фармакологии ТНЦ СО РАМН) | Способ клонирования in vitro регионарных стволовых клеток поджелудочной железы |
| ATE536374T1 (de) | 2006-09-01 | 2011-12-15 | Therapeutic Human Polyclonals Inc | Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren |
| EP2267153A1 (en) | 2009-05-26 | 2010-12-29 | Université Claude Bernard Lyon 1 | Identification of netrin-1 receptor unc5c gene mutation in solid cancers |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| JP2023131904A (ja) * | 2022-03-10 | 2023-09-22 | 国立大学法人愛媛大学 | 細胞の移植方法 |
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| EP0739412B1 (en) * | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| GB9517779D0 (en) | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| GB9517780D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| US5945577A (en) | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| RU2216592C2 (ru) * | 1998-01-16 | 2003-11-20 | Агробиоген Гмбх | Способ получения эмбрионов животных и способ выращивания животного из эмбрионов |
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| EP1017422A4 (en) | 2002-10-29 |
| NZ502129A (en) | 2005-02-25 |
| JP2001509361A (ja) | 2001-07-24 |
| CN1265599A (zh) | 2000-09-06 |
| CA2294916A1 (en) | 1999-01-14 |
| EP1017422A1 (en) | 2000-07-12 |
| WO1999001163A1 (en) | 1999-01-14 |
| BR9811657A (pt) | 2000-09-05 |
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Application publication date: 20070725 |