CN100591685C - 一种医药化合物的结晶形式 - Google Patents

一种医药化合物的结晶形式 Download PDF

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Publication number
CN100591685C
CN100591685C CN200580005979A CN200580005979A CN100591685C CN 100591685 C CN100591685 C CN 100591685C CN 200580005979 A CN200580005979 A CN 200580005979A CN 200580005979 A CN200580005979 A CN 200580005979A CN 100591685 C CN100591685 C CN 100591685C
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CN
China
Prior art keywords
compound
ray
powder diffraction
crystalline compounds
alpha
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Expired - Fee Related
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CN200580005979A
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English (en)
Chinese (zh)
Other versions
CN1922196A (zh
Inventor
M·H·罗克
H·罗佩斯迪戈
K·L·克里斯滕森
O·尼尔森
A·布尔
M·霍韦尔斯
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Cephalon Co Ltd
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H Lundbeck AS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN200580005979A 2004-02-27 2005-02-24 一种医药化合物的结晶形式 Expired - Fee Related CN100591685C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400326 2004-02-27
DKPA200400326 2004-02-27

Publications (2)

Publication Number Publication Date
CN1922196A CN1922196A (zh) 2007-02-28
CN100591685C true CN100591685C (zh) 2010-02-24

Family

ID=36607170

Family Applications (1)

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CN200580005979A Expired - Fee Related CN100591685C (zh) 2004-02-27 2005-02-24 一种医药化合物的结晶形式

Country Status (10)

Country Link
KR (1) KR20070012644A (es)
CN (1) CN100591685C (es)
AR (1) AR047821A1 (es)
CA (1) CA2762878C (es)
EA (1) EA200601566A1 (es)
ES (1) ES2397342T3 (es)
HK (1) HK1102087A1 (es)
TW (1) TW200530254A (es)
UA (1) UA90259C2 (es)
ZA (1) ZA200606556B (es)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NEUROTROPHIC3,9-BIS[(ALKYLTHIO)METHYL]-AND-BIS(ALKOXYMETHYL)-K-252a DERIVATIVES. MASAMI KANEKO, ET AL.J. MED. CHEM.,Vol.40 No.12. 1997
NEUROTROPHIC3,9-BIS[(ALKYLTHIO)METHYL]-AND-BIS(ALKOXYMETHYL)-K-252a DERIVATIVES. MASAMI KANEKO,ET AL.J.MED.CHEM,Vol.40 No.12. 1997 *

Also Published As

Publication number Publication date
AR047821A1 (es) 2006-02-22
TW200530254A (en) 2005-09-16
EA200601566A1 (ru) 2006-12-29
CA2762878A1 (en) 2005-09-09
KR20070012644A (ko) 2007-01-26
UA90259C2 (en) 2010-04-26
ES2397342T3 (es) 2013-03-06
ZA200606556B (en) 2008-02-27
HK1102087A1 (en) 2007-11-02
CA2762878C (en) 2014-08-19
CN1922196A (zh) 2007-02-28

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