CN100589703C - Synbiotic feed additive - Google Patents

Synbiotic feed additive Download PDF

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Publication number
CN100589703C
CN100589703C CN200710053206A CN200710053206A CN100589703C CN 100589703 C CN100589703 C CN 100589703C CN 200710053206 A CN200710053206 A CN 200710053206A CN 200710053206 A CN200710053206 A CN 200710053206A CN 100589703 C CN100589703 C CN 100589703C
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Prior art keywords
feed additive
synbiotic
bacillus subtilis
oligosaccharide
feed
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CN200710053206A
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CN101120726A (en
Inventor
侯永清
丁斌鹰
易丹
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Wuhan Pan-China Biotechnology Co., Ltd.
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Wuhan Polytechnic University
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Abstract

The present invention discloses a synbiotics feed additive, which is mixed and made by the useful viable, APS, non-digest oligosaccharide and the carrier according to a certain proportion. The presentinvention has the highlight advantages that the feed additive comprises many compositions which are useful for intestinal health and contains plant polysaccharides; which can effectively replace theantibiotics, compared with antibiotic, which is non-toxic, non-drug residues and beneficial for the health of animal and human, using the addictive can promote animal growth, improve feed conversion efficiency and reduce the incidence of disease.

Description

A kind of Synbiotic feed additive
Technical field
The invention belongs to herding or field of feed, relate to feed addictive, be specifically related to a kind of Synbiotic feed additive.
Background technology
Aquaculture presses for one of problem of solution most: improve quality, reduce medicament residue, reduce gradually even forbid that antibiotic etc is as feed addictive.Antibiotic can be prevented and treated Animal diseases for a long time effectively and promote growth of animal, but antibiotic lasting use can cause problems such as bacterial drug resistance and animal product medicament residue.Along with the enhancing of health of people consciousness, seek and develop green, feed addictive pollution-free, low-residual substitutes the focus that antibiotic has become current research.Synbiotics is the preparation that beneficial bacterium and compound sugar are united use, it can bring into play the somatotrophic double action of the physiologically active and the compound sugar of beneficial bacterium, by promoting the field planting in animal intestinal of exogenous viable bacteria, a kind of or limited several beneficial bacterium growth of selective stimulating and breeding, suppress the growth of harmful bacterium, thereby reach the purpose that promotes host health.Couplings such as probio and an amount of plant polyose have certain synergy.
Summary of the invention
The purpose of this invention is to provide a kind of Synbiotic feed additive of forming by useful viable bacteria and compound sugar and plant polyose, can effectively improve the health status of animal, promote growth of animal and improve food utilization efficiency.
The technical measures that the present invention adopts are as follows:
A kind of Synbiotic feed additive, its technical essential is: this feed addictive is to be the composition that 3: 0.2~0.5: 0.02~1: 1 mixed preparing forms by weight by useful viable bacteria and astragalus polyose and non-digest oligosaccharide and carrier.
Described useful viable bacteria is that the composition of bacillus subtilis (Bacillus subtilis) and bacillus licheniformis (BacillusLicheniformis) and bacillus subtilis and bacillus licheniformis are dry powder formulations, and every gram viable count is 200~50,000,000,000; Bacillus subtilis: the weight ratio of bacillus licheniformis is 2~5: 1; And non-digest oligosaccharide is xylo-oligosaccharide or kanjak mannan-oligosaccharides.Described carrier is silica or calcium carbonate or zeolite powder.
This Synbiotic feed additive consists of: the weight ratio of useful viable bacteria and astragalus polyose and non-digest oligosaccharide and carrier is 3: 0.2~0.5: 0.02~1: 1
The using method of feed addictive of the present invention is: addition is 0.01%~0.5% according to feed gross weight meter, directly this product is added in the animal and fowl fodder; Or this product and carrier be mixed and made into pre-mixing agent; Or be mixed and made into premix, the concentrate feed form livestock and poultry of feeding with other feed addictive or feedstuff.
Advantage of the present invention is: this feed addictive is grouped into by the one-tenth of multiple beneficial intestinal health, and contains plant polyose; Can effectively substitute the antibiotics additive; Compare with the antibiotics additive to have and have no side effect, drug residue free, be of value to the advantage of animal and human's class health; Use this feed addictive can promote growth of animal, improve feed efficiency, reduce disease incident.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further described.
Embodiment 1
With every gram viable count is that 50,000,000,000 bacillus subtilis dry powder and every gram viable count are 20,000,000,000 bacillus licheniformis dry powder, is combination in 2: 1 by weight, mixes, and obtains useful viable bacteria composition.Will this useful viable bacteria composition and astragalus polyose and xylo-oligosaccharide and silica by 3: 0.5: 0.02: 1 weight ratio combination, composition is mixed, obtain a kind of Synbiotic feed additive.
Press 0.5% of feed weight and add this feed addictive.
This routine recipe ratio is fit to pig usefulness, and trial effect is fine.
Carry out the weanling pig test with this Synbiotic feed additive.72 weanling pigs are divided into three groups, three repetitions of every component (hurdle), 8 on every hurdle.Piglet source, age in days, body weight are approaching, the sex unanimity.Three groups of basal diet unanimities are tested 1 group and are added 0.5% Synbiotic feed additive, test 2 groups and add colistine sulfate 20mg/kg, and the blank group does not add Synbiotic feed additive and colistine sulfate.The results are shown in Table 1.
Table 1 adds the influence of Synbiotic feed additive to the weanling pig growth performance
Figure C20071005320600051
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
The result shows, uses Synbiotic feed additive of the present invention, compares with the blank group, and the piglet daily gain improves 24.9%; The material anharmonic ratio reduces by 16.8%; Diarrhea rate reduces by 43.1%.Compare with the colistine sulfate group, the piglet daily gain improves 12.4%; Diarrhea rate reduces by 15.5%.
Embodiment 2
With every gram viable count is that 50,000,000,000 bacillus subtilis dry powder and every gram viable count are 20,000,000,000 bacillus licheniformis dry powder, is combination in 5: 1 by weight, mixes, and obtains useful viable bacteria composition.Will this useful viable bacteria composition and astragalus polyose and xylo-oligosaccharide and silica by 3: 0.2: 1: 1 weight ratio combination, composition is mixed, obtain a kind of Synbiotic feed additive.
This routine recipe ratio is fit to chicken usefulness, and trial effect is fine.
Carry out the feeding of broiler test with this Synbiotic feed additive.With 240 of a collection of Ai Weiyin meat chicks that hatches, be divided into 3 groups, 8 repetitions of every component (cage), 10 in every cage.Three groups of basal diet unanimities are tested 1 group and are added 0.01% Synbiotic feed additive, test 2 groups and add flavomycoin 4mg/kg, and the blank group does not add Synbiotic feed additive and flavomycoin.The results are shown in Table 2.
Table 2 adds Synbiotic feed additive to the growth of meat chicken Effect on Performance
Figure C20071005320600052
Annotate: the female different persons of colleague's shoulder marking-up represent significant difference (p<0.05).
The result shows, uses Synbiotic feed additive of the present invention, compares with the blank group, and the fryer daily gain improves 17.2%, expects that anharmonic ratio reduces by 12.9%.Can effectively substitute flavomycoin.

Claims (2)

1. Synbiotic feed additive, it is characterized in that: this feed addictive is to be the composition that 3: 0.2~0.5: 0.02~1: 1 mixed preparing forms by weight by useful viable bacteria and astragalus polyose and non-digest oligosaccharide and carrier, described useful viable bacteria is that the composition of bacillus subtilis (Bacillus subtilis) and bacillus licheniformis (Bacillus Licheniformis) and bacillus subtilis and bacillus licheniformis are dry powder formulations, and every gram viable count is 200~50,000,000,000; Bacillus subtilis: the weight ratio of bacillus licheniformis is 2~5: 1; And non-digest oligosaccharide is xylo-oligosaccharide or kanjak mannan-oligosaccharides.
2. feed addictive according to claim 1 is characterized in that: described carrier is silica or calcium carbonate or zeolite powder.
CN200710053206A 2007-09-13 2007-09-13 Synbiotic feed additive Expired - Fee Related CN100589703C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200710053206A CN100589703C (en) 2007-09-13 2007-09-13 Synbiotic feed additive

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Application Number Priority Date Filing Date Title
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CN100589703C true CN100589703C (en) 2010-02-17

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Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101715907B (en) * 2009-11-20 2012-06-27 长沙绿叶生物科技有限公司 Health care feed beneficial to pig and dog intestinal health and application thereof
CN101878858A (en) * 2010-06-23 2010-11-10 南京农业大学 Microecological composite growth-promoting feed additive for fish
CN102334610A (en) * 2011-09-05 2012-02-01 李文有 Antibiotic-free environment-friendly biological feed and production method thereof
CN102379373B (en) * 2011-09-29 2013-05-08 滨州市正元畜牧发展有限公司 Non-resistance cultivation method with joint application of feed strain, drinking water strain and biological isolation
CN102599345B (en) * 2012-01-13 2013-07-31 山东华牧天元农牧股份有限公司 Multicomponent biological compound agent for livestock
CN102630825B (en) * 2012-05-09 2014-01-29 袁礼江 Compound plant extract feed additive
CN102669435A (en) * 2012-06-05 2012-09-19 邵素英 Feed additive product
CN102763772B (en) * 2012-08-02 2013-05-08 北京华美源生物科技有限公司 Functional feed additive
CN103053806A (en) * 2012-12-27 2013-04-24 深圳华大基因科技有限公司 A synbiotic feed additive, and a preparation method and applications thereof
CN103120251B (en) * 2013-01-31 2014-02-12 武汉工业学院 Compound type natural plant feed additive and application
CN103330059B (en) * 2013-06-21 2014-09-17 四川恒通动物制药有限公司 Health care composition for livestock as well as preparation method and application thereof
CN104013650B (en) * 2014-05-29 2017-06-13 东北制药集团沈阳第一制药有限公司 Bacillus licheniformis and herbal polysaccharide composition and its preparation
CN105831399B (en) * 2016-03-30 2018-09-18 华南理工大学 A kind of probiotic feed additive and its production method and application
CN106376735B (en) * 2016-08-31 2019-04-05 长沙兴嘉生物工程股份有限公司 A kind of feeding Synbiotics and preparation method thereof and its application in livestock and poultry cultivation animal feed
CN107927328A (en) * 2017-04-26 2018-04-20 山东弘德农牧科技有限公司 A kind of preparation method and applications of feed composite microecologic agent
CN109007409A (en) * 2018-07-06 2018-12-18 华南农业大学 A kind of hatching Broiler chicks Synbiotics mouthspray preparation and preparation method thereof
CN109329628A (en) * 2018-12-05 2019-02-15 河北农业大学 A kind of pig feed additive and its preparation method and application
CN112753883A (en) * 2021-01-21 2021-05-07 云南师范大学 Enzyme-enriched bacterial element-containing broiler chicken anti-feed composite additive and preparation method thereof
CN112753853A (en) * 2021-01-21 2021-05-07 云南师范大学 Enzyme-enriched bacterial element-enriched piglet anti-bacterial feed composite additive and preparation method thereof

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
The use of probiotics in aquaculture. F. J. Gatesoupe*.aquaculture,No.180. 1999
The use of probiotics in aquaculture. F. J. Gatesoupe*.aquaculture,No.180. 1999 *
合生素的研究进展. 苗晓微,李娜,吴健,张敏.饲料工业,第26卷第14期. 2005
合生素的研究进展. 苗晓微,李娜,吴健,张敏.饲料工业,第26卷第14期. 2005 *
安全饲料添加剂研究进展. 张华琦,杨正德.江西饲料,第1期. 2006
安全饲料添加剂研究进展. 张华琦,杨正德.江西饲料,第1期. 2006 *
绿色饲料添加剂的研究进展. 井庆川,魏祥法,刘辉,史勇.家禽科学,第11期. 2006
绿色饲料添加剂的研究进展. 井庆川,魏祥法,刘辉,史勇.家禽科学,第11期. 2006 *

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