CN100528146C - 控制活性成分释放的治疗系统 - Google Patents

控制活性成分释放的治疗系统 Download PDF

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Publication number
CN100528146C
CN100528146C CNB038094851A CN03809485A CN100528146C CN 100528146 C CN100528146 C CN 100528146C CN B038094851 A CNB038094851 A CN B038094851A CN 03809485 A CN03809485 A CN 03809485A CN 100528146 C CN100528146 C CN 100528146C
Authority
CN
China
Prior art keywords
layer
tablet
coating
release
therapy system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB038094851A
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English (en)
Chinese (zh)
Other versions
CN1649571A (zh
Inventor
L·马吉
U·孔特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jagotec AG
Original Assignee
Jagotec AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jagotec AG filed Critical Jagotec AG
Publication of CN1649571A publication Critical patent/CN1649571A/zh
Application granted granted Critical
Publication of CN100528146C publication Critical patent/CN100528146C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB038094851A 2002-03-12 2003-03-12 控制活性成分释放的治疗系统 Expired - Fee Related CN100528146C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2002A000514 2002-03-12
IT2002MI000514A ITMI20020514A1 (it) 2002-03-12 2002-03-12 Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi

Publications (2)

Publication Number Publication Date
CN1649571A CN1649571A (zh) 2005-08-03
CN100528146C true CN100528146C (zh) 2009-08-19

Family

ID=11449490

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038094851A Expired - Fee Related CN100528146C (zh) 2002-03-12 2003-03-12 控制活性成分释放的治疗系统

Country Status (12)

Country Link
US (1) US20050095295A1 (enExample)
EP (1) EP1482915B1 (enExample)
JP (1) JP4664595B2 (enExample)
CN (1) CN100528146C (enExample)
AT (1) ATE454887T1 (enExample)
AU (1) AU2003239789A1 (enExample)
CA (1) CA2478406C (enExample)
DE (1) DE60330949D1 (enExample)
DK (1) DK1482915T3 (enExample)
ES (1) ES2339438T3 (enExample)
IT (1) ITMI20020514A1 (enExample)
WO (1) WO2003075897A1 (enExample)

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EP1429739A1 (en) 2001-09-21 2004-06-23 Egalet A/S Polymer release system
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
GB0203296D0 (en) 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
DE602004031096D1 (de) 2003-03-26 2011-03-03 Egalet As Morphin-system mit kontrollierter freisetzung
AP2006003602A0 (en) * 2003-09-19 2006-04-30 Sun Pharmaceutical Ind Ltd Oral drug delivery system
US10213387B2 (en) 2003-09-19 2019-02-26 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
US10226428B2 (en) 2003-09-19 2019-03-12 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
WO2006122069A2 (en) * 2005-05-09 2006-11-16 Azur Pharma Formulations of mast cell stabilizing agents for delivery to the colon
CN101188999B (zh) * 2005-06-03 2012-07-18 尹格莱特股份有限公司 用于递送分散在分散介质中的活性物质的药物传递系统
BRPI0520797B8 (pt) * 2005-11-18 2021-05-25 Accu Break Tech Inc forma de dosagem farmacêutica comprimida em bicamadas
WO2007149860A1 (en) * 2006-06-19 2007-12-27 Accu-Break Technologies, Inc. Segmented pharmaceutical dosage forms
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
CA2715584A1 (en) * 2008-02-15 2009-10-08 Sun Pharma Advanced Research Company Ltd. Oral controlled release tablet
US20100112052A1 (en) * 2008-10-31 2010-05-06 Vincent Chen Osmotic tablet with a compressed outer coating
ES2607209T3 (es) 2009-02-06 2017-03-29 Egalet Ltd. Composiciones farmacéuticas resistentes al abuso
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
CA2840765A1 (en) * 2011-06-29 2013-01-03 Ranbaxy Laboratories Limited Multilayered dosage form
US9549899B2 (en) 2012-07-06 2017-01-24 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
CN104490838B (zh) * 2014-11-20 2017-03-01 河北医科大学 一种骨架型缓控释片剂及其制备方法和应用
KR102851614B1 (ko) 2016-02-04 2025-08-29 신돔 파마, 인크. 장애 치료를 위한 중수소화된 돔페리돈 조성물 및 방법
EP3981392A1 (en) * 2016-05-05 2022-04-13 Triastek, Inc. Controlled release dosage form
ES2958616T3 (es) 2017-03-08 2024-02-12 Cinrx Pharma Llc Formulaciones farmacéuticas de floroglucinol y trimetilfloroglucinol
US12478612B2 (en) 2017-06-30 2025-11-25 Cindome Pharma, Inc. Deuterated domperidone compositions, methods, and preparation
KR20240125702A (ko) 2017-06-30 2024-08-19 신돔 파마, 인크. 중수소화 돔페리돈 조성물, 방법, 및 제조
EP3970701B1 (en) * 2018-06-27 2025-05-07 Amneal Complex Products Research LLC Self-regulating osmotic gastroretentive drug delivery systems
WO2020027927A1 (en) * 2018-07-30 2020-02-06 Insta Therapeutics, Inc. Sublingual diltiazem and methods of use
CN113274363B (zh) * 2021-04-29 2023-02-10 珠海润都制药股份有限公司 一种吲达帕胺制剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2213539Y (zh) * 1994-04-29 1995-11-29 天津市激光技术研究所 包衣上带有小孔的缓释药片
US5650169A (en) * 1993-05-31 1997-07-22 Jagotec Ag Pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times

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GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
IT1201136B (it) * 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
US4810502A (en) * 1987-02-27 1989-03-07 Alza Corporation Pseudoephedrine brompheniramine therapy
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
US5256440A (en) * 1992-06-22 1993-10-26 Merck & Co., Inc. Process for producing a tablet core aperture
US5376771A (en) * 1992-07-07 1994-12-27 Merck & Co., Inc. High speed process for preparing orifices in pharmaceutical dosage forms
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
US5783793A (en) * 1996-02-29 1998-07-21 Merck & Co., Inc. Process for producing a plurality of holes in dosage forms using a laser beam deflected by an acousto-optic deflector
ES2203963T3 (es) * 1997-05-30 2004-04-16 Osmotica Corp. Dispositivo osmotico multicapa.
US6004584A (en) * 1998-03-02 1999-12-21 The Procter & Gamble Company Highly absorbent body powders
CA2378829A1 (en) * 1999-07-20 2001-01-25 Merck & Co., Inc. Sustained release drug dispersion delivery device
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650169A (en) * 1993-05-31 1997-07-22 Jagotec Ag Pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times
CN2213539Y (zh) * 1994-04-29 1995-11-29 天津市激光技术研究所 包衣上带有小孔的缓释药片

Also Published As

Publication number Publication date
US20050095295A1 (en) 2005-05-05
ES2339438T3 (es) 2010-05-20
CA2478406A1 (en) 2003-09-18
CA2478406C (en) 2011-02-08
WO2003075897A1 (en) 2003-09-18
EP1482915B1 (en) 2010-01-13
ITMI20020514A0 (it) 2002-03-12
DK1482915T3 (da) 2010-04-19
DE60330949D1 (de) 2010-03-04
EP1482915A1 (en) 2004-12-08
AU2003239789A1 (en) 2003-09-22
JP2005526757A (ja) 2005-09-08
CN1649571A (zh) 2005-08-03
JP4664595B2 (ja) 2011-04-06
ATE454887T1 (de) 2010-01-15
ITMI20020514A1 (it) 2003-09-12

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Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20090819

Termination date: 20180312