CN100500295C - 用于对限定的液量进行操作的装置 - Google Patents

用于对限定的液量进行操作的装置 Download PDF

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Publication number
CN100500295C
CN100500295C CNB2004100880794A CN200410088079A CN100500295C CN 100500295 C CN100500295 C CN 100500295C CN B2004100880794 A CNB2004100880794 A CN B2004100880794A CN 200410088079 A CN200410088079 A CN 200410088079A CN 100500295 C CN100500295 C CN 100500295C
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CN
China
Prior art keywords
described device
surface district
district
reagent
inlet
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Expired - Lifetime
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CNB2004100880794A
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English (en)
Chinese (zh)
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CN1597119A (zh
Inventor
格特·布兰肯施泰因
拉尔夫-彼得·彼得斯
霍尔格·巴托斯
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Boehringer Ingelheim Microparts GmbH
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Boehringer Ingelheim Microparts GmbH
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Publication of CN1597119A publication Critical patent/CN1597119A/zh
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Composite Materials (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CNB2004100880794A 2003-06-13 2004-06-11 用于对限定的液量进行操作的装置 Expired - Lifetime CN100500295C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10326607A DE10326607A1 (de) 2003-06-13 2003-06-13 Vorrichtung zum Handhaben von Flüssigkeiten
DE10326607.0 2003-06-13

Publications (2)

Publication Number Publication Date
CN1597119A CN1597119A (zh) 2005-03-23
CN100500295C true CN100500295C (zh) 2009-06-17

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CNB2004100880794A Expired - Lifetime CN100500295C (zh) 2003-06-13 2004-06-11 用于对限定的液量进行操作的装置

Country Status (5)

Country Link
US (2) US7931868B2 (https=)
EP (1) EP1495799A3 (https=)
JP (1) JP4891532B2 (https=)
CN (1) CN100500295C (https=)
DE (1) DE10326607A1 (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN109663621A (zh) * 2019-01-17 2019-04-23 京东方科技集团股份有限公司 一种微纳结构基板的制备方法、微纳流控芯片及器件

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DE10326607A1 (de) * 2003-06-13 2005-01-05 Steag Microparts Gmbh Vorrichtung zum Handhaben von Flüssigkeiten
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ES2361169T3 (es) * 2005-01-27 2011-06-14 Boehringer Ingelheim Microparts Gmbh Uso de un dispositivo para el análisis de muestras de líquido.
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JP4861353B2 (ja) * 2008-02-01 2012-01-25 日本電信電話株式会社 フローセル
BRPI0907148B1 (pt) * 2008-02-27 2021-01-12 Boehringer Ingelheim Microparts Gmbh dispositivo para a separação do plasma
SE533514C2 (sv) * 2008-06-16 2010-10-12 Aamic Ab Analysanordning och förfarande
JP5242503B2 (ja) * 2008-06-16 2013-07-24 オーミック・アーベー アッセイ装置および方法
US8974749B2 (en) * 2008-06-16 2015-03-10 Johnson & Johnson Ab Assay device and method
JP4852573B2 (ja) * 2008-06-18 2012-01-11 日本電信電話株式会社 フローセル
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US9216413B2 (en) * 2009-07-07 2015-12-22 Boehringer Ingelheim Microparts Gmbh Plasma separation reservoir
JP5618556B2 (ja) * 2010-01-28 2014-11-05 株式会社日立ハイテクノロジーズ 核酸分析装置，核酸分析反応デバイス、および核酸分析用反応デバイス用基板
EP2360114B1 (en) * 2010-02-12 2012-12-12 Consejo Superior De Investigaciones Científicas Method of producing a polymer stamp for the reproduction of devices comprising microstructures and nanostructures and corresponding device
KR100961874B1 (ko) * 2010-04-05 2010-06-09 주식회사 나노엔텍 외부동력 없이 유체가 이동하는 유체분석용 칩
JP5177915B2 (ja) * 2011-04-25 2013-04-10 日本電信電話株式会社 フローセル
KR20130085994A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 다수의 시약 셀을 갖는 분석 장치
PL398979A1 (pl) * 2012-04-25 2013-10-28 Scope Fluidics Spólka Z Ograniczona Odpowiedzialnoscia Urzadzenie mikroprzeplywowe i uklad mikroprzeplywowy obejmujacy jedno lub wiecej urzadzen mikroprzeplywowych
GB201217390D0 (en) * 2012-09-28 2012-11-14 Agplus Diagnostics Ltd Test device and sample carrier
JP6120440B2 (ja) * 2013-04-30 2017-04-26 国立研究開発法人産業技術総合研究所 マイクロチャンバー及び液体の混合方法
JP5685630B2 (ja) * 2013-07-19 2015-03-18 Ｊｆｅエンジニアリング株式会社 マイクロチップ
CN104209489B (zh) * 2014-08-26 2016-06-08 中国科学院力学研究所 一种实现金属构件移动微压铸成型的装置
JP6796371B2 (ja) 2014-11-28 2020-12-09 デクセリアルズ株式会社 マイクロ流路作製用原盤の製造方法
FR3056927B1 (fr) * 2016-09-30 2021-07-09 Ecole Polytech Procede microfluidique de manipulation de microgouttes
JP2017024170A (ja) * 2016-10-18 2017-02-02 大日本印刷株式会社 マイクロ流路装置
KR101993305B1 (ko) * 2017-06-01 2019-06-26 주식회사 스몰머신즈 유체 분석용 마이크로 칩
WO2021021771A1 (en) * 2019-07-30 2021-02-04 Texas Tech University System Microfluidic pipette aspirators for large-scale analysis of single cells, clusters and their sub-populations
DE102020210219A1 (de) 2020-08-12 2022-02-17 Robert Bosch Gesellschaft mit beschränkter Haftung Flusszelle zum Integrieren einer Prozessierungseinheit in eine mikrofluidische Vorrichtung und Verfahren zum Prozessieren einer Probenflüssigkeit
CN112666050B (zh) * 2020-11-30 2023-06-02 江苏科技大学 一种功能表面亲水性能测试装置及表征方法
CN113797986B (zh) * 2021-10-11 2023-05-26 苏州美翎生物医学科技有限公司 一种可微调毛细管同轴排列的微流控芯片
JP2024029792A (ja) * 2022-08-23 2024-03-07 東洋製罐グループホールディングス株式会社 マイクロ流体デバイス、検査システム、及び検査方法
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DE102024114091A1 (de) * 2024-05-21 2025-11-27 pluriSelect Life Science UG (haftungsbeschränkt) & Co. KG Schicht mit mikrostrukturierter Oberfläche

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CN109663621A (zh) * 2019-01-17 2019-04-23 京东方科技集团股份有限公司 一种微纳结构基板的制备方法、微纳流控芯片及器件

Also Published As

Publication number Publication date
CN1597119A (zh) 2005-03-23
US20110172109A1 (en) 2011-07-14
DE10326607A1 (de) 2005-01-05
US20050026346A1 (en) 2005-02-03
US7931868B2 (en) 2011-04-26
JP2005003688A (ja) 2005-01-06
EP1495799A2 (de) 2005-01-12
EP1495799A3 (de) 2007-04-04
US8318110B2 (en) 2012-11-27
JP4891532B2 (ja) 2012-03-07

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Granted publication date: 20090617