JP3116709U - 微小流路チップ - Google Patents
微小流路チップ Download PDFInfo
- Publication number
- JP3116709U JP3116709U JP2005007535U JP2005007535U JP3116709U JP 3116709 U JP3116709 U JP 3116709U JP 2005007535 U JP2005007535 U JP 2005007535U JP 2005007535 U JP2005007535 U JP 2005007535U JP 3116709 U JP3116709 U JP 3116709U
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- capillary
- capillaries
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- microchannel chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00511—Walls of reactor vessels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00657—One-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00729—Peptide nucleic acids [PNA]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
【解決手段】 本考案の微小流路チップでは、基板上に並列若しくは直列に接続される複数の溝が形成され、互いに異なる化学修飾が施されたキャピラリーが前記複数の溝にそれぞれ埋設され、これらの埋設された複数の前記キャピラリーに流体を供給し検出データを取得することができる。当該微小流路チップにより多項目の化学・生化学機能が同時に測定される。
【選択図】 図1
Description
11 表面
12 流路
13〜16 溝
18 ダミーキャピラリー
21〜24 キャピラリー
25〜28 流路
30、32 キャピラリー
31、33 流路
40 基板
41 バルブキャピラリー
42 ダミーキャピラリー
43a〜43d、43e 角型キャピラリー
50 基板
51、52 フルオレセイン放出キャピラリー
Claims (7)
- 基板上に並列若しくは直列に接続される複数の溝が形成され、互いに異なる化学修飾が施されたキャピラリーが前記複数の溝にそれぞれ埋設され、これらの埋設された複数の前記キャピラリーに流体を供給し検出データを取得することを特徴とする微小流路チップ。
- 前記キャピラリーは抗体を当該キャピラリーの内壁に固定した抗体固定キャピラリーであり、前記流体は抗原溶液であることを特徴とする請求項1記載の微小流路チップ。
- 前記キャピラリーは抗原を当該キャピラリーの内壁に固定した抗原固定キャピラリーであり、前記流体は抗体溶液であることを特徴とする請求項1記載の微小流路チップ。
- 溶液を前記キャピラリーに導入した後、前記キャピラリーの両端はシリコンオイルで封止されることを特徴とする請求項1記載の微小流路チップ。
- 基板上に並列若しくは直列に接続される複数の溝が形成され、抗体を固定したキャピラリーが前記複数の溝にそれぞれ埋設され、これらの埋設された複数の前記キャピラリーに抗原溶液を供給し検出データを取得することを特徴する微小流路チップ。
- 基板上に並列若しくは直列に接続される複数の溝が形成され、抗原を固定したキャピラリーが前記複数の溝にそれぞれ埋設され、これらの埋設された複数の前記キャピラリーに抗体溶液を供給し検出データを取得することを特徴する微小流路チップ。
- ELISA法により前記キャピラリーに発色反応を生じさせ、その発色濃度から検出データを取得することを特徴とする請求項1、請求項5、若しくは請求項6記載の微小流路チップ。
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005007535U JP3116709U (ja) | 2005-09-13 | 2005-09-13 | 微小流路チップ |
PCT/JP2006/317996 WO2007032316A1 (ja) | 2005-09-13 | 2006-09-11 | 微小流路チップ |
CN2006800336124A CN101263392B (zh) | 2005-09-13 | 2006-09-11 | 微流道芯片 |
EP06783269A EP1936382A1 (en) | 2005-09-13 | 2006-09-11 | Microchannel chip |
US11/991,852 US20090215158A1 (en) | 2005-09-13 | 2006-09-11 | Micro Flow Channel Chip |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005007535U JP3116709U (ja) | 2005-09-13 | 2005-09-13 | 微小流路チップ |
Publications (1)
Publication Number | Publication Date |
---|---|
JP3116709U true JP3116709U (ja) | 2005-12-15 |
Family
ID=37864909
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005007535U Expired - Lifetime JP3116709U (ja) | 2005-09-13 | 2005-09-13 | 微小流路チップ |
Country Status (5)
Country | Link |
---|---|
US (1) | US20090215158A1 (ja) |
EP (1) | EP1936382A1 (ja) |
JP (1) | JP3116709U (ja) |
CN (1) | CN101263392B (ja) |
WO (1) | WO2007032316A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010071045A1 (ja) * | 2008-12-19 | 2010-06-24 | 公立大学法人大阪府立大学 | イムノアッセイ用キャピラリー及びそれを用いたキャピラリーイムノアッセイ法 |
US9372133B2 (en) | 2010-06-30 | 2016-06-21 | Metaboscreen Co., Ltd. | Microchemical chip, producing method thereof and method for using the microchemical chip |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8405944B2 (en) * | 2007-10-09 | 2013-03-26 | Schweitzer Engineering Laboratories Inc | Distributed bus differential protection using time-stamped data |
FR2928209B1 (fr) * | 2008-03-03 | 2011-04-22 | Rhodia Operations | Procede et installation de determination d'au moins un parametre d'une transformation physique et/ou chimique |
KR101102532B1 (ko) * | 2008-07-10 | 2012-01-03 | 삼성전자주식회사 | 시약 카트리지, 시약 카트리지를 구비하는 미세유동장치, 그 제조방법, 및 이를 이용한 시료분석방법 |
CN102341693B (zh) * | 2009-03-07 | 2013-11-20 | 惠普开发有限公司 | 分析器和使用该分析器进行感测的方法 |
JP5242465B2 (ja) * | 2009-03-18 | 2013-07-24 | 株式会社東芝 | 検体検出装置 |
US8554385B2 (en) * | 2009-09-11 | 2013-10-08 | Schweitzer Engineering Laboratories Inc. | Systems and methods for monitoring and controlling electrical system stability |
WO2013134739A1 (en) * | 2012-03-08 | 2013-09-12 | Cyvek, Inc. | Microfluidic assay operating system and methods of use |
US10065403B2 (en) | 2009-11-23 | 2018-09-04 | Cyvek, Inc. | Microfluidic assay assemblies and methods of manufacture |
US9651568B2 (en) | 2009-11-23 | 2017-05-16 | Cyvek, Inc. | Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays |
US9700889B2 (en) | 2009-11-23 | 2017-07-11 | Cyvek, Inc. | Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results |
WO2011063408A1 (en) * | 2009-11-23 | 2011-05-26 | Cyvek, Inc. | Method and apparatus for performing assays |
US9500645B2 (en) | 2009-11-23 | 2016-11-22 | Cyvek, Inc. | Micro-tube particles for microfluidic assays and methods of manufacture |
US9759718B2 (en) | 2009-11-23 | 2017-09-12 | Cyvek, Inc. | PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use |
US9855735B2 (en) | 2009-11-23 | 2018-01-02 | Cyvek, Inc. | Portable microfluidic assay devices and methods of manufacture and use |
JP5978287B2 (ja) * | 2011-03-22 | 2016-08-24 | サイヴェク・インコーポレイテッド | マイクロ流体装置並びに製造及び使用の方法 |
CN102749443B (zh) * | 2011-04-22 | 2014-10-01 | 国家纳米科学中心 | 双层微流控芯片器件及其在免疫检测中的用途 |
US9211521B2 (en) * | 2012-09-19 | 2015-12-15 | Millifluidica, Llc | Fluidic channel coated with metal catalysts and devices and methods relating thereto |
US10228367B2 (en) | 2015-12-01 | 2019-03-12 | ProteinSimple | Segmented multi-use automated assay cartridge |
CN106771226B (zh) * | 2016-11-10 | 2019-10-08 | 中国科学院成都生物研究所 | 一种基于玻璃毛细管的牛血清白蛋白检测探针及其制备方法和应用 |
WO2018170412A1 (en) * | 2017-03-16 | 2018-09-20 | Case Western Reserve University | Biochip having microchannel provided with capturing agent for performing cytological analysis |
CN112368077B (zh) * | 2018-12-07 | 2023-11-24 | 元素生物科学公司 | 流动池装置及其用途 |
US11446661B2 (en) | 2019-03-11 | 2022-09-20 | Beijing Boe Technology Development Co., Ltd. | Microfluidic channel and preparation method and operation method thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508200A (en) * | 1992-10-19 | 1996-04-16 | Tiffany; Thomas | Method and apparatus for conducting multiple chemical assays |
US5976896A (en) * | 1994-06-06 | 1999-11-02 | Idexx Laboratories, Inc. | Immunoassays in capillary tubes |
JP3938982B2 (ja) | 1997-08-29 | 2007-06-27 | オリンパス株式会社 | Dnaキャピラリィ |
US6162341A (en) * | 1998-09-11 | 2000-12-19 | The Perkin-Elmer Corporation | Multi-channel capillary electrophoresis device including sheath-flow cuvette and replacable capillary array |
JP3441058B2 (ja) | 1999-12-03 | 2003-08-25 | 理化学研究所 | キャピラリーゲル電気泳動用マイクロチップおよびその製造方法 |
US6610499B1 (en) | 2000-08-31 | 2003-08-26 | The Regents Of The University Of California | Capillary array and related methods |
US20060057576A1 (en) | 2002-03-12 | 2006-03-16 | Jerzy Paszkowski | Microcapillary hybridization chamber |
JP2004061320A (ja) * | 2002-07-29 | 2004-02-26 | Kawamura Inst Of Chem Res | マイクロ流体デバイスの送液方法 |
JP4073023B2 (ja) | 2003-11-07 | 2008-04-09 | 財団法人新産業創造研究機構 | 微小流路デバイスおよびその作製方法 |
-
2005
- 2005-09-13 JP JP2005007535U patent/JP3116709U/ja not_active Expired - Lifetime
-
2006
- 2006-09-11 WO PCT/JP2006/317996 patent/WO2007032316A1/ja active Application Filing
- 2006-09-11 CN CN2006800336124A patent/CN101263392B/zh not_active Expired - Fee Related
- 2006-09-11 EP EP06783269A patent/EP1936382A1/en not_active Withdrawn
- 2006-09-11 US US11/991,852 patent/US20090215158A1/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010071045A1 (ja) * | 2008-12-19 | 2010-06-24 | 公立大学法人大阪府立大学 | イムノアッセイ用キャピラリー及びそれを用いたキャピラリーイムノアッセイ法 |
US9372133B2 (en) | 2010-06-30 | 2016-06-21 | Metaboscreen Co., Ltd. | Microchemical chip, producing method thereof and method for using the microchemical chip |
Also Published As
Publication number | Publication date |
---|---|
WO2007032316A1 (ja) | 2007-03-22 |
CN101263392B (zh) | 2012-10-31 |
CN101263392A (zh) | 2008-09-10 |
US20090215158A1 (en) | 2009-08-27 |
EP1936382A1 (en) | 2008-06-25 |
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