CN100490809C - 包含西替利嗪和伪麻黄碱的片剂 - Google Patents

包含西替利嗪和伪麻黄碱的片剂 Download PDF

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Publication number
CN100490809C
CN100490809C CNB02812975XA CN02812975A CN100490809C CN 100490809 C CN100490809 C CN 100490809C CN B02812975X A CNB02812975X A CN B02812975XA CN 02812975 A CN02812975 A CN 02812975A CN 100490809 C CN100490809 C CN 100490809C
Authority
CN
China
Prior art keywords
tablet
pseudoephedrine
cetirizine
unit
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB02812975XA
Other languages
English (en)
Chinese (zh)
Other versions
CN1520285A (zh
Inventor
D·法纳拉
A·吉绍
M·贝尔韦尔
M·德莱尔斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Farchim SA
Original Assignee
UCB Farchim SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Farchim SA filed Critical UCB Farchim SA
Publication of CN1520285A publication Critical patent/CN1520285A/zh
Application granted granted Critical
Publication of CN100490809C publication Critical patent/CN100490809C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines Containing Plant Substances (AREA)
CNB02812975XA 2001-06-28 2002-06-10 包含西替利嗪和伪麻黄碱的片剂 Expired - Lifetime CN100490809C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30125001P 2001-06-28 2001-06-28
US60/301,250 2001-06-28
EP01115807 2001-06-28
EP01115807.8 2001-06-28

Publications (2)

Publication Number Publication Date
CN1520285A CN1520285A (zh) 2004-08-11
CN100490809C true CN100490809C (zh) 2009-05-27

Family

ID=56290291

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB02812975XA Expired - Lifetime CN100490809C (zh) 2001-06-28 2002-06-10 包含西替利嗪和伪麻黄碱的片剂

Country Status (22)

Country Link
EP (1) EP1404304B1 (enExample)
JP (1) JP4041460B2 (enExample)
KR (1) KR100926410B1 (enExample)
CN (1) CN100490809C (enExample)
AT (1) ATE432068T1 (enExample)
AU (1) AU2002345024B2 (enExample)
BR (1) BR0210650A (enExample)
CA (1) CA2451519C (enExample)
CZ (1) CZ20033454A3 (enExample)
DK (1) DK1404304T3 (enExample)
EE (1) EE05357B1 (enExample)
ES (1) ES2324769T3 (enExample)
HU (1) HU229803B1 (enExample)
MX (1) MXPA03010430A (enExample)
NZ (1) NZ530289A (enExample)
PL (1) PL206069B1 (enExample)
PT (1) PT1404304E (enExample)
RO (1) RO122476B1 (enExample)
RU (1) RU2286784C2 (enExample)
SI (1) SI1404304T1 (enExample)
SK (1) SK287645B6 (enExample)
WO (1) WO2003002098A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9694007B2 (en) 2010-02-01 2017-07-04 Hanmi Science Co., Ltd. Oral complex composition comprising pseudoephedrine and levocetirizine

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090029314A (ko) * 2001-06-28 2009-03-20 유씨비 파쉼 소시에떼아노님 세티리진 및 슈도에페드린을 포함하는 정제
KR100698400B1 (ko) 2004-04-14 2007-03-23 이은주 탈모증 및 전립선비대증 치료를 위한 약제학적 조성물
US20100172984A1 (en) * 2006-06-06 2010-07-08 Bijay Kumar Padhi tablet dosage form comprising cetirizine and pseudoephedrine
PT2099442E (pt) 2006-12-26 2015-02-10 Pharmacyclics Inc Métodos de utilização de inibidores de histona desacetilase e monitorização de biomarcadores em terapia de combinação
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
CN102665807A (zh) 2010-01-05 2012-09-12 微剂量治疗技术公司 吸入设备和方法
ES2705244T3 (es) 2010-06-16 2019-03-22 Inflammatory Response Res Inc Levocetirizina y montelukast para el tratamiento de la gripe y del resfriado común
CN102302497A (zh) * 2011-05-18 2012-01-04 天圣制药集团股份有限公司 一种治疗过敏性鼻炎的制剂及其制备方法
KR20130009553A (ko) 2011-07-15 2013-01-23 한미약품 주식회사 몬테루카스트 또는 이의 약학적으로 허용가능한 염 및 레보세티리진 또는 이의 약학적으로 허용가능한 염을 함유하는 캡슐 제제
UA110853C2 (uk) 2011-09-13 2016-02-25 Фармасайклікс, Інк. Лікарські форми інгібітора гістондеацетилази у комбінації з бендамустином та їхнє застосування
KR101372324B1 (ko) * 2012-02-09 2014-03-13 동국대학교 경주캠퍼스 산학협력단 알러지성 비염 치료를 위한 한방 치료제 및 슈도에페드린을 함유한 복합서방형의 약제학적 조성물
EP2968309A4 (en) 2013-03-13 2016-08-31 Inflammatory Response Res Inc USE OF LEVOCETRIXIN AND MONTELUKAST IN THE TREATMENT OF VASCULARITY
CN105228700A (zh) 2013-03-13 2016-01-06 炎症反应研究公司 左西替利嗪和孟鲁司特在治疗自身免疫病中的用途
ES2660494T3 (es) 2013-03-13 2018-03-22 14779507 Uso de levocetirizina y montelukast en el tratamiento de una lesión traumática
JP2017526728A (ja) 2014-09-15 2017-09-14 インフラマトリー・レスポンス・リサーチ・インコーポレイテッド 炎症介在性状態の治療におけるレボセチリジン及びモンテルカスト
WO2016140630A1 (en) 2015-03-05 2016-09-09 PHARMACTIVE ILAÇ SANAYI VE TlCARET A. Ş. An effervescent composition comprising levocetirizine and pseudoephedrine
US20210236430A1 (en) * 2020-02-03 2021-08-05 Johnson & Johnson Consumer Inc. Single layer chewable tablet comprising cetirizine
WO2021236518A1 (en) 2020-05-19 2021-11-25 IRR, Inc. Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1250371A (zh) * 1997-03-14 2000-04-12 Ucb公司 用于控制释放活性物质的药物组合物
US6171618B1 (en) * 1996-05-29 2001-01-09 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469009B1 (en) * 1996-04-08 2002-10-22 Ucb, S.A. Pharmaceutical compositions for the treatment of rhinitis
US6267986B1 (en) * 1999-09-24 2001-07-31 Ranbaxy Laboratories Limited Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171618B1 (en) * 1996-05-29 2001-01-09 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
CN1250371A (zh) * 1997-03-14 2000-04-12 Ucb公司 用于控制释放活性物质的药物组合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9694007B2 (en) 2010-02-01 2017-07-04 Hanmi Science Co., Ltd. Oral complex composition comprising pseudoephedrine and levocetirizine

Also Published As

Publication number Publication date
EP1404304A1 (en) 2004-04-07
HUP0400386A2 (hu) 2004-08-30
EE05357B1 (et) 2010-12-15
CA2451519A1 (en) 2003-01-09
ES2324769T3 (es) 2009-08-14
RU2286784C2 (ru) 2006-11-10
PL366800A1 (en) 2005-02-07
CA2451519C (en) 2007-11-06
RU2004101231A (ru) 2005-04-20
ATE432068T1 (de) 2009-06-15
BR0210650A (pt) 2004-10-05
KR100926410B1 (ko) 2009-11-12
MXPA03010430A (es) 2004-12-06
HU229803B1 (en) 2014-07-28
JP4041460B2 (ja) 2008-01-30
PL206069B1 (pl) 2010-06-30
JP2004536829A (ja) 2004-12-09
RO122476B1 (ro) 2009-07-30
SI1404304T1 (sl) 2009-10-31
HUP0400386A3 (en) 2006-02-28
AU2002345024B2 (en) 2006-09-07
CZ20033454A3 (cs) 2004-08-18
SK287645B6 (sk) 2011-05-06
WO2003002098A1 (en) 2003-01-09
PT1404304E (pt) 2009-06-26
NZ530289A (en) 2004-11-26
KR20040007756A (ko) 2004-01-24
EP1404304B1 (en) 2009-05-27
CN1520285A (zh) 2004-08-11
SK15502003A3 (sk) 2004-05-04
DK1404304T3 (da) 2009-07-13
EE200400005A (et) 2004-02-16

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20090527

CX01 Expiry of patent term