CN100488507C - 含有泮托拉唑作为活性成分的剂型 - Google Patents
含有泮托拉唑作为活性成分的剂型 Download PDFInfo
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- CN100488507C CN100488507C CNB2004800121299A CN200480012129A CN100488507C CN 100488507 C CN100488507 C CN 100488507C CN B2004800121299 A CNB2004800121299 A CN B2004800121299A CN 200480012129 A CN200480012129 A CN 200480012129A CN 100488507 C CN100488507 C CN 100488507C
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- Prior art keywords
- pantoprazole
- dosage form
- tablet
- pharmaceutical composition
- coating
- Prior art date
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Images
Landscapes
- Medicinal Preparation (AREA)
Abstract
Description
CHN分析 | C | H | N | S |
理论值 | 46.58 | 3.91 | 10.19 | 7.77 |
测定值 | 46.33 | 3.89 | 10.04 | 7.83 |
泮托拉唑钠倍半水合物 | 有机溶剂 | 水 | 标题化合物的产量 | 熔点℃ | 水含量% |
50g | 异丙醇300ml | 300ml | 45.4g | 196-197 | 4.4-4.5 |
50g | 异丙醇300ml | 120ml | 45.9g | 196-197 | 4.3 |
50g | 乙醇300ml | 300ml | 45.8g | 197-198 | 4.6 |
50g | 丙酮300ml | 300ml | 45.6g | 195-196 | 4.6-4.7 |
实施例 | 用作粘合剂的PVP | 崩解[分钟] |
B8 | PVP 25 | 7 |
B9 | PVP 25 | 6.5 |
B10 | PVP 30 | 10.5 |
B11 | PVP 17 | 9 |
B12 | PVP 12 | 7.5 |
C1 | PVP 90 | 10.5 |
Claims (11)
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EP03010328 | 2003-05-08 | ||
EP03010328.7 | 2003-05-08 | ||
EP04001754.3 | 2004-01-28 |
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CN 200910128639 Division CN101524336B (zh) | 2003-05-08 | 2004-05-07 | 含有泮托拉唑作为活性成分的剂型 |
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CN1784227A CN1784227A (zh) | 2006-06-07 |
CN100488507C true CN100488507C (zh) | 2009-05-20 |
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CNB2004800121299A Expired - Fee Related CN100488507C (zh) | 2003-05-08 | 2004-05-07 | 含有泮托拉唑作为活性成分的剂型 |
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CN101596165B (zh) * | 2008-06-04 | 2012-07-11 | 永信药品工业(昆山)有限公司 | 泮托拉唑钠肠溶微丸 |
CN101836985A (zh) * | 2009-03-17 | 2010-09-22 | 北京利乐生制药科技有限公司 | 一种含有左旋泮托拉唑镁的药物制剂及其制备方法 |
CN107629037A (zh) * | 2017-10-26 | 2018-01-26 | 荆门医药工业技术研究院 | 一种制备左旋泮托拉唑镁二水合物的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6365184B1 (en) * | 1996-01-08 | 2002-04-02 | Astrazeneca Ab | Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a NSAID |
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Publication number | Priority date | Publication date | Assignee | Title |
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US6365184B1 (en) * | 1996-01-08 | 2002-04-02 | Astrazeneca Ab | Oral pharmaceutical dosage forms comprising a proton pump inhibitor and a NSAID |
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Publication number | Publication date |
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CN101524336B (zh) | 2013-12-18 |
CN1784227A (zh) | 2006-06-07 |
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