CN100467050C

CN100467050C - Composition formula for treating leucoderma and its preparation method

Info

Publication number: CN100467050C
Application number: CNB200510022648XA
Authority: CN
Inventors: 夏金陵
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-12-22
Filing date: 2005-12-22
Publication date: 2009-03-11
Anticipated expiration: 2025-12-22
Also published as: CN1824247A

Abstract

A Chinese medicine composed of an internally applied one and an externally applied one for treating lenkoderma is disclosed. Its internally applied is prepared from 30 Chinese-medicinal materials including astragalus root, fleece flower root, Chinese angelica root, Chuan-xiong rhizome, etc. Its externally applied one is prepared from 6 Chinese-medicinal materials including dodder seed, dahurian angelica root, asarum herb, realgar, etc.

Description

Treat leukodermic Chinese medicine composition and preparation method thereof

Technical field

The present invention relates to Chinese medicine and preparation method, be specifically related to treat leukodermic Chinese medicine composition and preparation method thereof.

Background technology

All diseases have a common basic factor, are exactly the positive QI-insufficiency of human body, and modern medicine thinks that immunity reduces.Ancient medicine was also once done summary highly to this factor and pathogeny, and " interior warp " has meaning: " institute of heresy gathers, and its gas must be empty ", this also is the basic characteristics of pathogenesis.Simultaneously " interior warp " proposed the basic concept of " healthy energy deposit in, heresy can not be done " again aspect prevent disease.

Although whether the power of human body falls ill and extraneous pathogen has relation, its key is human righteousness's power, and " all kinds of diseases and ailments are all taken advantage of a weak point and given birth to " also has been described, vitiligo is no exception.

" General Treatise on the Cause and Symptoms of Diseases " has cloud: the leucoderma person, face and neck health skin and flesh complexion changed are white, and be different with yellowish pink, the pain of also not itching, the leucoderma of meaning.This also is by " ailment said due to cold or exposure is fought in skin, and the vim and vigour discord is given birth to also." clear Golden Mirror of Medicine more points out, this disease is " Shi Zhiyi early ... just obey Herba Spirodelae ball, inferior clothes Herba Xanthii cream.”

Vitiligo be a kind of common, easily the diagnosis and the disease of refractory.Mental burden is heavier after being ill for many patients, brings certain influence for work, life, so should give due attention to the treatment of this disease.Primary disease is from etiological analysis, more complicated, and cause is multiple, but that key factor is a QI and blood is unfavorable, and ailment said due to cold or exposure is invaded outward, and passages through which vital energy circulates is not smooth, failure of skin and muscle to be nourished, QI-blood circulation is unfavorable, causes thereby the local skin pathological changes.This disease is a difficult and complicated illness, and up to the present, its pathogenesis is still not clear, and treatment is still relatively more difficult, does not still have a kind of therapy both at home and abroad all patients are cured fully.

According to modern medicine study, vitiligo is tyrosine---the dysfunction of tryrosinase system in epidermis and the corium intersection melanocyte, causes the local skin depigmentation.Its morbidity may be relevant with autoimmune response, psychic trauma, malnutrition, local excitation, neuro chemistry factor, endocrine regulation, copper or zinc Developmental and Metabolic Disorder or the like (if lack in the body copper also can influence melanin form and vitiligo takes place).

Summary of the invention

The objective of the invention is to: leukodermic Chinese medicine composition of a kind of treatment and preparation method thereof is provided, adopts said composition oral administration and externally used for curing vitiligo, each the crude drug medicine source in the compositions is extensive, and cost is lower, short treating period, and curative effect is fast, has no side effect.

Technical solution of the present invention is: said composition is made up of the BAIDIANJING for oral administration and the purplish or white patches on the skin tincture that disappears of external, wherein, BAIDIANJING for oral administration is made into by weight by following crude drug: Herba Xanthii grass 1000 grams, the Radix Astragali 600 grams, Fructus Atriplicis Sibiricae, Herba Siegesbeckiae, each 500 gram of Radix Pseudostellariae, Semen Astragali Complanati, Fructus Psoraleae, Rhizoma Wenyujin Concisum, Fructus Mori, Semen Sesami Nigrum, each 300 gram of Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Herba Ecliptae, Pyritum, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Codonopsis, Radix Rehmanniae Preparata, each 200 gram of GANQIZI, Radix Bupleuri (processed with vinegar), Rhizoma Et Radix Notopterygii, Poria, Semen Cuscutae, Radix Paeoniae Rubra, paddy, each 150 gram of Fructus Hordei Germinatus, duckweed spirodela, each 100 gram of the Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, each 60 gram of the Radix Angelicae Dahuricae; Wherein, the external purplish or white patches on the skin tincture that disappears is made into by weight by following crude drug: Semen Cuscutae 50 grams, Fructus Psoraleae 30 grams, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), Herba Asari, each 20 gram of Realgar, Semen Oroxyli 15 grams.

The preparation method of BAIDIANJING: at first, Herba Siegesbeckiae is mixed thoroughly with 150 gram yellow wine, and cage steamed about three hours, and taking-up is dried, and steams so repeatedly and shines seven times, shines Resina Toxicodendri, grinds then to be smalls or machine powder, and Pyritum was concocted 241 years by " Chinese medicine processing complete works " method of forging; Then, Herba Siegesbeckiae closes in the BAIDIANJING other crude drug and dries and grind into fine powder and mix thoroughly and wait to do ball and use; Secondly, with the Radix Astragali 200 grams, GANQIZI 200 grams, Radix Rehmanniae Preparata 200 grams, Herba Xanthii grass 600 grams add the dense juice that takes of suitable water; At last, with this extract for water pill such as the seeds of a tung oil tree big BAIDIANJING.

The instructions of taking of BAIDIANJING: at every turn obey 8 grams, day clothes 3 times.The child can obey 6 grams (13 years old).But this ball is not taken by pregnant women.During treating, the suitable normal Exposure to Sunlight in affected part.Serveing on three months is a course of treatment, and the lighter 1-2 course of treatment, severe patient can serve on 3-4 the course of treatment.

The BAIDIANJING function with cure mainly: QI and blood regulating, expelling wind and removing dampness, the logical knot that stagnates of a surname, strengthening spleen, tonifying kidney.Cure mainly various vitiligo.

Prove that according to clinical practice the course of disease heals long, it is promptly slow to take a turn for the better, and the healing chance is also little; Preferably the course of disease is being good below 5 years.Be valued for and adhere to taking medicine, the course of treatment is longer, and improvement rate is higher.Outside work person and cooperation Exposure to Sunlight person better efficacy.BAIDIANJING energy for oral administration human body immunity improving power is especially remarkable to disharmony between QI and blood patient effect.

The preparation method of the purplish or white patches on the skin that disappears tincture: at first, each crude drug dries, and grinds into coarser powder; Secondly, soak 14 days after-filtration with 600 milliliters of 75% ethanol and remove slag, filtrate bottled the purplish or white patches on the skin tincture that disappears.

The using method of the purplish or white patches on the skin that disappears tincture: pick up the purplish or white patches on the skin tincture that disappears with cotton rod at every turn and be coated with the affected part, day is coated with 2 times.Must massage behind the coating, rub gently in the above about 5-10 minute, can play the merit of promoting blood circulation to remove obstruction in the collateral like this with cotton rod.

The function of the purplish or white patches on the skin that disappears tincture: the sterilization of dispeling the wind, promoting blood circulation to remove obstruction in the collateral.Cure mainly vitiligo.

Press: external disappears, and had better not to be stained with lip pleasing to the eye for the purplish or white patches on the skin tincture, stimulates uncomfortable sense otherwise have.

Each component among the present invention has following effect: Fructus Atriplicis Sibiricae, the Radix Bupleuri (processed with vinegar) lung qi dispersing is soothing the liver, the therapeutic method to keep the adverse QI flowing downwards and blood; Semen Astragali Complanati is the key medicine of " smart asthenia "; Herba Xanthii grass, duckweed spirodela have the diffusing wind heat of dispelling; Pyritum may contain mantoquita; Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling; Rhizoma Wenyujin Concisum, Rhizoma Chuanxiong can lead to the gas in the blood, meet " control wind and control blood earlier, blood is lived wind from going out " intention; The light gas of Rhizoma Et Radix Notopterygii body is dense, and the benefaction edema caused by disorder of QI can loose and can manage it, about merit is thorough, all over reaching limbs, for robbing random key medicine anyway; Radix Rehmanniae Preparata is enriched blood and is treated damage; Semen Cuscutae is solid innocent partially, the temperature compensation three yin meridians with benefit smart with, its property is soft and moist, so and temperature is not dry, benefit is not and high, both the tonifying YIN essence had helped kidney yang again, made Yin grows while yang is generating; Fructus Psoraleae the kidney invigorating warming the spleen; Fructus Ligustri Lucidi, Herba Ecliptae YIN nourishing training unit grows and oiliness, mends and not dry; Radix Angelicae Dahuricae awakening consciousness, the wind that can loose dehumidifying; Radix Polygoni Multiflori, Fructus Mori, Semen Sesami Nigrum nourishing the liver and kidney, spermatogenesis nourishes blood; Radix Codonopsis, Radix Pseudostellariae, the Rhizoma Atractylodis Macrocephalae, Poria, paddy Fructus Hordei Germinatus replenishing QI to invigorate the spleen to mend the day after tomorrow, are cured the disease and should be paid attention to spleen invigorating; The Herba Siegesbeckiae expelling wind and dampness, bone and muscle strengthening, long eyebrow is sent out, improve visual and auditory acuity, liver and kidney tonifying, especially two buds, the Fructus Hordei Germinatus spleen reinforcing, Fructus Setariae Germinatus is gone into stomach, Fructus Hordei Germinatus master liter, Fructus Setariae Germinatus the master fall, can make taste and close, lifting is orderly, and modern medicine shows that two buds have multiple beneficial human chitinase and trace element, can promote the human body metabolism; Radix Codonopsis, Radix Astragali replenishing QI to invigorate the spleen Gu Wei, but modern medicine is thought enhancing immunity, especially the Radix Astragali " combination of Chinese and Western medicine magazine " is 1989 (67,327) but the page or leaf old Ji Youyun: the Radix Astragali has antiviral, enhancing antibody forms, prolong effects such as cells in vitro time-to-live, and can improve killing of VAK cell and do active; The GANQIZI the kidney invigorating that makes eye bright also has the merit of antiinflammatory.

The leukodermic Chinese medicine composition of treatment of the present invention is made up of BAIDIANJING for oral administration and the external purplish or white patches on the skin tincture that disappears, and so combination has QI and blood regulating altogether, expelling wind and removing dampness, and the logical knot that stagnates of a surname, strengthening spleen, tonifying kidney, curing vitiligo total effective rate are 96%.

Curative effect judging standard: white macula disappears, and recovers the normal colour of skin, is recovery from illness; White macula disappears or obviously dwindles, and is produce effects, promptly recovers the gross area of the colour of skin〉60%; White macula disappears or the person of dwindling is effectively; Skin lesion no change before and after the treatment is for invalid.

Therapeutic outcome: successively treat 70 examples over nearly 13 years, at minimum 13 years old of age, the maximum is 72 years old, woman's 38 examples, man's 32 examples.Course of disease weak point person is half a year approximately, and elder is about 15 years.Cured person 40 examples (57%) in 70 examples; Produce effects 18 examples (26%); Effective 10 examples (13%); Invalid 3 examples (4%); Total effective rate is 96%.

The specific embodiment

Said composition is made up of the BAIDIANJING for oral administration and the purplish or white patches on the skin tincture that disappears of external, wherein, BAIDIANJING for oral administration is made into by weight by following crude drug: Herba Xanthii grass 1000 grams, the Radix Astragali 600 grams, Fructus Atriplicis Sibiricae, Herba Siegesbeckiae, each 500 gram of Radix Pseudostellariae, Semen Astragali Complanati, Fructus Psoraleae, Rhizoma Wenyujin Concisum, Fructus Mori, Semen Sesami Nigrum, each 300 gram of Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Herba Ecliptae, Pyritum, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Codonopsis, Radix Rehmanniae Preparata, each 200 gram of GANQIZI, Radix Bupleuri (processed with vinegar), Rhizoma Et Radix Notopterygii, Poria, Semen Cuscutae, Radix Paeoniae Rubra, paddy, each 150 gram of Fructus Hordei Germinatus, duckweed spirodela, each 100 gram of the Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, each 60 gram of the Radix Angelicae Dahuricae; Wherein, the external purplish or white patches on the skin tincture that disappears is made into by weight by following crude drug: Semen Cuscutae 50 grams, Fructus Psoraleae 30 grams, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), Herba Asari, each 20 gram of Realgar, Semen Oroxyli 15 grams.

Case 1: Sha Wanmei, the woman, 63 years old, married, east, building, cities and towns, Chuzhou District Huaihe River, Huai neighbourhood committee.Trouble vitiligo year is surplus, imitates though the Chinese and Western treatment is all deceived, and spending economy is had a surplus for ten thousand yuan, and development rapidly.Examine the equal large stretch of white macula of meeting portion, neck and two handss, neither ache and also do not itch.The bodily form is richer, and there is purple gas on the pale tongue limit, but pulse condition is flat.To sum up think: invasion of the body by blended pathogenic wind and dampness, qi-blood disharmony, disease is weakened body resistance for a long time.For oral administration with BAIDIANJING, took about about six months front and back, and the white macula recovery from illness of disappearing is not visited and fallen ill.

Case 2: Zhang Zhaohua, the woman, 72 years old, married, Chuzhou District San Bao township, Huai associating group.Closely reach 3 years according to stating the trouble vitiligo, though all invalid through how tame hospitalize.Examine the especially whole white maculas of denomination of meeting portion, the eyebrow border is also white, and two the back of the hand and finger all scatter white macula, and the back chest all has.Feel the pulse string and a little less than, body of the tongue is thin, surplus nothing is uncomfortable.To sum up dialectically be: rheumatism is invaded in pore, causes stagnation of QI-blood, with the passing of time deficiency of both QI and blood, the not flourish skin of blood is controlled suitable QI and blood regulating for suffering from, the logical knot that stagnates of expelling wind and removing dampness a surname, strengthening spleen, tonifying kidney is a method, obeys BAIDIANJING and is coated with the purplish or white patches on the skin tincture that disappears through controlling three courses of treatment and visiting the morbidity again of having a surplus in 2 years.

Case 3: Li Aifeng, woman, 13 years old, student, Huai yellow sign indicating number unity group.Suffer from buccal white macula and neck white macula two places half a year, through BAIDIANJING for oral administration be coated with about course of treatment of the purplish or white patches on the skin tincture that disappears outward and heal, visiting had a surplus in 6 years falls ill again.

Case 4: Jiang, the woman, 54 years old, married, cities and towns, Huaihe River fish market neighbourhood committee.Suffer from vitiligo and closely reach 5 years, all control invalid.With BAIDIANJING for oral administration be coated with and disappear two courses of treatment of purplish or white patches on the skin tincture and heal, visit surplus morbidity again in 5 years outward.

Case 5: the summer, the man, 58 years old, married, cities and towns, Huaihe River, Huai six pearl neighbourhood committees.It is surplus to suffer from vitiligo year, and right neck white macula has silver dollar big one, and white macula has coin big on the left lip, on hand, on the wing, chest all scatters the white macula that differs in size.Have a surplus half a year through the clothes BAIDIANJING and not see advance and retreat, back BAIDIANJING for oral administration and the external purplish or white patches on the skin tincture that disappears, three recoveries from illness courses of treatment of front and back treatment, morbidity again more than 10 years, but still stay slightly dark trace, as pay no heed to, also can't see.

Claims

1. treat leukodermic Chinese medicine composition, it is characterized in that: said composition is made up of the BAIDIANJING for oral administration and the purplish or white patches on the skin tincture that disappears of external, wherein, BAIDIANJING master for oral administration is made into by weight by following crude drug: Herba Xanthii grass 1000 grams, the Radix Astragali 600 grams, Fructus Atriplicis Sibiricae, Herba Siegesbeckiae, each 500 gram of Radix Pseudostellariae, Semen Astragali Complanati, Fructus Psoraleae, Rhizoma Wenyujin Concisum, Fructus Mori, Semen Sesami Nigrum, each 300 gram of Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Herba Ecliptae, Pyritum, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Codonopsis, Radix Rehmanniae Preparata, each 200 gram of GANQIZI, Radix Bupleuri (processed with vinegar), Rhizoma Et Radix Notopterygii, Poria, Semen Cuscutae, Radix Paeoniae Rubra, paddy, each 150 gram of Fructus Hordei Germinatus, duckweed spirodela, each 100 gram of the Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, each 60 gram of the Radix Angelicae Dahuricae; Wherein, the external purplish or white patches on the skin tincture that disappears is made into by weight by following crude drug: Semen Cuscutae 50 grams, Fructus Psoraleae 30 grams, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), Herba Asari, each 20 gram of Realgar, Semen Oroxyli 15 grams.

2. the preparation method of the BAIDIANJING in the leukodermic Chinese medicine composition of treatment according to claim 1, it is characterized in that: at first, Herba Siegesbeckiae is mixed thoroughly with 150 gram yellow wine, cage steamed about three hours, taking-up is dried, and steams so repeatedly and shines seven times, shines Resina Toxicodendri, grinding is smalls or machine powder, and Pyritum was concocted 241 years by " Chinese medicine processing complete works " method of forging; Then, Herba Siegesbeckiae closes in the BAIDIANJING other crude drug and dries and grind into fine powder and mix thoroughly and wait to do ball and use; Secondly, with the Radix Astragali 200 grams, GANQIZI 200 grams, Radix Rehmanniae Preparata 200 grams, Herba Xanthii grass 600 grams add the dense juice that takes of suitable water; At last, with this extract for water pill such as the seeds of a tung oil tree big BAIDIANJING.

3. the preparation method of the purplish or white patches on the skin tincture that disappears in the leukodermic Chinese medicine composition of treatment according to claim 1 is characterized in that: at first, each crude drug dries, and grinds into coarser powder; Secondly, soak 14 days after-filtration with 600 milliliters of 75% ethanol and remove slag, filtrate is bottled that the purplish or white patches on the skin tincture that disappears is coated with usefulness outward.