CN103127399B - Chinese medicine decoction for treating Parkinson disease - Google Patents
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- CN103127399B CN103127399B CN201310074740.5A CN201310074740A CN103127399B CN 103127399 B CN103127399 B CN 103127399B CN 201310074740 A CN201310074740 A CN 201310074740A CN 103127399 B CN103127399 B CN 103127399B
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Abstract
The invention relates to the field of medicine formulas and in particular relates to a Chinese medicine decoction for treating Parkinson disease. The Chinese medicine decoction comprises the following Chinese herbal components in parts by weight: 17-22 parts of white paeony root, 13-17 parts of rehmannia glutinosa, 17-22 parts of Chinese angelica, 13-17 parts of liquorice, 17-22 parts of Chinese wolfberry fruit, 17-22 parts of astragalus mongholicus, 13-17 parts of tortoiseshell, 17-22 parts of fleece-flower root, 22-28 parts of uncaria rhynchophylla, 13-17 parts of gastrodiae elata, 3-7 parts of scorpio, 13-17 parts of red-rooted salvia root, 8-12 parts of baical skullcap root, 8-12 parts of dogwood and 1-2 parts of antelope horn powder. A preparation method of the Chinese medicine decoction comprises the following steps of: mixing the Chinese herbal components, namely the white paeony root, the rehmannia glutinosa, the Chinese angelica, the liquorice, the Chinese wolfberry fruit, the astragalus mongholicus, the tortoiseshell, the fleece-flower root, the uncaria rhynchophylla, the gastrodiae elata, the scorpio, the red-rooted salvia root, the baical skullcap root and the dogwood to obtain a mixture, mixing the mixture with water, decocting to obtain a decocted mixture, deslagging to obtain filtrate, grinding antelope horn into powder, and then uniformly mixing the antelope horn powder and the filtrate to obtain the Chinese medicine decoction. The Chinese medicine decoction is low in cost, has a high curative effect on treating the Parkinson disease, has no toxic and side effect and has the functions of tonifying, nourishing yin, calming liver, relieving dizziness, activating blood circulation and dispersing blood stasis so as to achieve a favorable effect on treatment of the Parkinson disease.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind ofly treat Parkinsonian Chinese medicine decoction.
Background technology
As everyone knows, parkinson disease (Parkinson disease, PD) are a kind of central nervous system degenerative diseases of serious harm healthy elder.Its motor symptoms shows as static tremor, myotonia, bradykinesia and postural balance obstacle etc.Up to now, the Parkinsonian cause of disease of idiopathic still imperfectly understands, and it is generally acknowledged mainly relevant with the factor such as age ageing, h and E.In brain in nigrostriatum the minimizing of dopamine neuron and disease have a substantial connection.Along with the increase of the aged number of China, China's patients with Parkinson disease, up to 2,000,000, accounts for 1% left and right of aging population at present, estimates annual newly-increased sufferer 100,000 people.Parkinsonian high incidence, high disability rate have been brought heavy economy and psychological burden to society and family.Chinese medicine is one " great treasure-house ", the important source of Ye Shi China medical domain autonomous innovation.The traditional Chinese medical science belongs to tremor syndrome by parkinson disease, and card belongs to deficiency in origin and excess in superficiality, take void as main, empty dirty at Liver and kidney spleen three, sees in fact wind, fire, expectorant, the stasis of blood.Dispelling pathogenic wind and eliminating phlegm relieving convulsion and nourishing YIN to lower pathogenic fire YANG hyperactivity suppressing are the Important Rules of clinical treatment.Tradition Western medicine therapy is still located core status in the treatment of PD, yet the serious side reaction that Long-term taking medicine brings also causes people's concern day by day, impels people to examine traditional remedies closely from new angle, also from new approach, finds the effective ways for the treatment of PD.The historical origin of Chinese medicine PD for a long time, is made a general survey of clinical practice for many years, and Chinese medicine is sure to the curative effect of PD.Chinese and Western medicine combination, has fully demonstrated it to doctor trained in Western medicine attenuation synergistic, the complementary advantage of blocking deteriorated case.Existing clinical research shows, the combination of Chinese and Western medicine can reduce dopamine preparation consumption, effectively antagonism and the caused toxic and side effects for the treatment of Western medicine again, and Chinese medicine has the dual function for the treatment of PD protopathy and complication.And for a long time, the research of Chinese medicine PD concentrates entirely on the caused dyskinesia symptom of disease by attention, ignored the improvement effect to the non-dyskinesia symptom of PD.Therefore, should go into overdrive to carry out the research of this respect, embody on the whole better the superiority of Chinese medicine PD.
Summary of the invention
Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, a kind of Parkinsonian Chinese medicine decoction for the treatment of is provided, cost is low, treatment parkinson disease curative effect is high, have no side effect, there is tonification, YIN nourishing, suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., invigorate blood circulation, the function of blood stasis dispelling, to reach the good effect for the treatment of parkinson disease.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind ofly treat Parkinsonian Chinese medicine decoction, it is characterized in that the weight portion that crude drug forms is: the Radix Paeoniae Alba 17～22, Radix Rehmanniae Preparata 13～17, Radix Angelicae Sinensis 17～22, Radix Glycyrrhizae 13～17, Fructus Lycii 17～22, the Radix Astragali 17～22, Carapax et Plastrum Testudinis 13～17, the Radix Polygoni Multiflori 17～22, Ramulus Uncariae Cum Uncis 22～28, Rhizoma Gastrodiae 13～17, Scorpio 3～7, Radix Salviae Miltiorrhizae 13～17, Radix Scutellariae 8～12, Fructus Corni 8～12, Cornu Saigae Tataricae powder 1～2, by the above-mentioned Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Carapax et Plastrum Testudinis, the Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Rhizoma Gastrodiae, Scorpio, Radix Salviae Miltiorrhizae, Radix Scutellariae, Fructus Corni crude drug is soaked in water after mixing, the filtrate of removing slag after decocting to obtain, after being pulverized, Cornu Saigae Tataricae mixs homogeneously with described filtrate.
The invention has the beneficial effects as follows, cost is low, and treatment parkinson disease curative effect is high, has no side effect, and has tonification, YIN nourishing, suppressing the hyperactive liver, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., invigorates blood circulation, the function of blood stasis dispelling, to reach the good effect for the treatment of parkinson disease.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
The present embodiment is got above-mentioned 15 20 grams of the taste crude drug Radix Paeoniae Albas, 15 grams, Radix Rehmanniae Preparata, 20 grams of Radix Angelicae Sinensis, 15 grams, Radix Glycyrrhizae, 20 grams of Fructus Lycii, 20 grams of the Radixs Astragali, 15 grams of Carapax et Plastrum Testudiniss, 20 grams of the Radixs Polygoni Multiflori, 25 grams of Ramulus Uncariae Cum Uncis, 15 grams, Rhizoma Gastrodiae, 5 grams of Scorpios, 15 grams of Radix Salviae Miltiorrhizaes, 10 grams of Radix Scutellariaes, 10 grams of Fructus Corni, 1.5 grams of Cornu Saigae Tataricae powders.At room temperature by the above-mentioned Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Carapax et Plastrum Testudinis, the Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Rhizoma Gastrodiae, Scorpio, Radix Salviae Miltiorrhizae, Radix Scutellariae, Fructus Corni 14 taste crude drug add purifies waste water 800 milliliters, soak 6 hours, then boil with high heat slow fire and decoct 120 minutes, remove slag to obtain approximately 150 milliliters of filtrates, medicinal residues add 200 milliliters, water again, decoct 30 minutes, remove slag to obtain approximately 30 milliliters of filtrates, be total to obtain approximately 180 milliliters of medicine juice, then to 1.5 grams of the fine powders that adds in 180 milliliters of medicine juice Cornu Saigae Tataricae to grind to form, stir, every bu morning, noon and afternoon 3 times are oral, each approximately 60 milliliters of warm medicine soup (medicine) being taken before meal are used, 30 days per courses for the treatment of.
Cost of material of the present invention is low, and treatment parkinson disease curative effect is high, has no side effect.In side, the Radix Paeoniae Alba has nourishing blood to suppress the hyperactive liver, slow middle pain relieving, the yin fluid astringing of enriching blood, all effects of yin nourishing suppressing the hyperactive liver.Modern pharmacology research shows, the Radix Paeoniae Alba has coronary artery dilating, reduce blood pressure, and antiplatelet aggregation, the effect such as hepatoprotective protects the liver, spasmolysis and analgesia.Chinese angelica blood supplementing is invigorated blood circulation, and menstruction regulating and pain relieving is gas medicine in blood, and be longer than moving and invigorate blood circulation, the Radix Paeoniae Alba yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, is cloudy medicine in blood, is good at quiet and yin fluid astringing.One is moving one quiet, is furnished with mutually the effect of the treating blood disorders of nourishing blood.Radix Paeoniae Alba sour in the mouth, obtains wooden gas the purest, and Radix Glycyrrhizae sweet in the mouth obtains native gas the thickest, and two medicine 5 use, have the magical effect of sour and sweet drugs can transforme into YIN, play altogether the effectiveness of preserving YIN with astringents and nourishing blood, relieving spasm to stop pain.Radix Rehmanniae Preparata, the Radix Paeoniae Alba all can be nourished blood and enrich blood, and belong to quiet medicine together, but Radix Rehmanniae Preparata to enrich blood to fill out marrow into kidney be main, it is main that the Radix Paeoniae Alba is enriched blood into liver yin nourishing easing the affected liver; The sweet temperature of Radix Rehmanniae Preparata, Radix Paeoniae Alba acid is cold, and two medicines share, and Liver and kidney is also mended, and replenishing the kidney(water)to nourish the liver(wood), fully demonstrates saying of " yi and Kui are derived from the same origin ".Fructus Lycii has the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, the effect of nourishing the lung to arrest cough.Modern pharmacology research finds that Fructus Lycii contains the antioxidant such as abundant lycium barbarum polysaccharide, beta-carotene, vitamin E, selenium and flavonoid, has good antioxidation.The Radix Astragali is the panacea of QI invigorating, sweet in the mouth, and feeble QI temperature, gas is thin and taste is dense, can rise to fall, and the yang aspect of yang is also, nontoxic, specially QI invigorating.Modern study finds that the Radix Astragali has immunologic function, enhancing body anoxia enduring and stress ability, the promotion organism metabolism of enhancing, improves cardiac function, blood pressure lowering, protects the liver, regulates blood glucose, antibacterial and antiviral, the effect of parahormone sample etc.Carapax et Plastrum Testudinis has the effect of nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone.< < property of medicine opinion > > states that it is " nontoxic." enter liver, kidney channel.Modern pharmacology research finds that Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate, can improve the phagocytic function of reticuloendothelial system, and the leukopenia that cyclophosphamide is caused has protective effect.Can improve body antineoplastic immunocompetence, animal " deficiency of YIN " syndrome pathological model is had to remarkable protective effect.The invigorating the liver and kidney of Radix Polygoni Multiflori Preparata function, benefiting essence-blood, black beard and hair, bone and muscle strengthening, the old and feeble sign of improving middle-aged and elderly people, can promote the raising of body immunity, suppresses the deposition of lipofuscin in organ.The Radix Polygoni Multiflori can also coronary artery dilating, and blood fat reducing, promotes erythrocytic generation, and coronary heart disease, hyperlipidemia, old anemia, brain degeneration, senilism sign etc. are had to preventive effect.MAO-B activity in rat, the in vitro brain of mice is had to remarkable inhibitory action.Senile rat is taken Radix Polygoni Multiflori 2 months, can improve the function of senile rat striatal dopamine nervous system.Radix Polygoni Multiflori delaying senility function is relevant with its antioxidation, and Aged Mice gavages Radix Polygoni Multiflori water drug-decocting concentrating liquid, can obviously strengthen SOD activity in blood, reduces LPO content in mouse core, liver, cerebral tissue and in blood.The material base of Radix Polygoni Multiflori efficacy effect is mainly phospholipid, Anthraquinones, glucose glycoside etc.Ramulus Uncariae Cum Uncis sweet in the mouth is cool in nature, main enters Liver Channel, belongs to liver wind calming drug, has the effect of heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, is the Liver Channel excess of YANG, pneumatic key medicine.Ramulus Uncariae Cum Uncis sweet in the mouth suppressing the hyperactive liver cool in nature, the prosperous mark of the inclined to one side treating the liver of clearing heat for calming endogenous wind, the easing the affected liver yin nourishing cold in nature of Radix Paeoniae Alba sour in the mouth, suppressing the hyperactive liver, have nourishing the liver body and hold back the kind tonifying liver void of merit that irritability, suppressing the hyperactive liver sun make irritability not recklessly act this, Papillary giving consideration to both the incidental and fundamental, the effect of playing altogether easing the affected liver yin nourishing, suppressing the hyperactive liver to relieve the wind syndrome.Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, endogenous wind stopping relieving convulsion merit are arrogated to oneself suppressing the hyperactive liver; Scorpio endogenous wind stopping relieving convulsion, removing obstruction in the collateral to relieve pain are longer than endogenous wind stopping, and the two 5 use is played the effect of suppressing the hyperactive liver to relieve the wind syndrome, removing obstruction in the collateral to relieve pain altogether.Ramulus Uncariae Cum Uncis sweet in the mouth is cool in nature enters liver, heart channel heat clearing away suppressing the hyperactive liver, the moving card for the treatment of the liver hot blast is arrogated to oneself in the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Rhizoma Gastrodiae sweet flat soft and moist enter Liver Channel nutrient solution suppressing the hyperactive liver, endogenous wind stopping YANG hyperactivity suppressing for control the panacea of wind be used for disturbing on stirring-up of pathogenic wind in the interior resulting from deficiency, wind-phlegm due to all cards, two medicines share, and play altogether the merit of heat clearing away suppressing the hyperactive liver, endogenous wind stopping relieving convulsion.Rhizoma Gastrodiae sweet in the mouth, property are put down, and have endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, the effect of dispelling wind and removing obstruction in the collateral.Modern pharmacological research shows that Rhizoma Gastrodiae is rich in gastrodine, Vanillin, protein, aminoacid and trace element; there is analgesia, calmness, increase blood flow, reduce vascular resistance, improve the effects such as blood supply, also there is the effects such as antioxidation and Cell protection film, brain healthy, slow down aging.Rhizoma Gastrodiae has the effect of suppressing the hyperactive liver to relieve the wind syndrome, Radix Scutellariae clearing away heat-fire, and deflection is not high to make Liver Channel, and the two 5 use brings out the best in each other.Research shows, Ramulus Uncariae Cum Uncis is to distributing and have influence in the body of Rhizoma Gastrodiae, and in compatibility hindbrain, the distribution of Rhizoma Gastrodiae is risen, and confirmed that Ramulus Uncariae Cum Uncis can draw that Rhizoma Gastrodiae is up enters brain, the therapeutical effect of performance Rhizoma Gastrodiae.Scorpio acrid in the mouth, property is flat, poisonous.Main enter Liver Channel, property is apt to away alter, and has both calmed down liver-wind, and expel wind to dredge collateral again has the effect of good endogenous wind stopping relieving convulsion, for controlling the key medicine of spasm tic.Radix Salviae Miltiorrhizae bitter in the mouth, cold nature.Energy blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves.Modern pharmacology research finds that Radix Salviae Miltiorrhizae is rich in TANSHINONES, protocatechualdehyde, protocatechuic acid, danshensu, vitamin E etc., and energy coronary artery dilator, increases coronary flow, improves myocardial ischemia and cardiac function, improves microcirculation; Can improve body's hypoxia tolerance; There is anticoagulation, promote fibrinolytic, suppress platelet aggregation, suppress thrombotic effect; Can reduce blood fat, suppress coronary atherosclerosis and form; Suppress or alleviate hepatocellular degeneration, necrosis and inflammatory reaction, promoting liver cell regeneration, and have anti-fibrosis effect; There is antibacterial, antiinflammatory, antitumor action.Radix Salviae Miltiorrhizae can make cerebral cortex spontaneous electric activity amplitude reduce, and repetitive stimulation causes that after-discharge threshold value raises.Radix Salviae Miltiorrhizae has the vigor that suppresses the Camp Phosphodiesterase of each tissue in vitro tests, especially with brain and lung, suppress the most responsive, inferring corticocerebral inhibitory action, may be by suppressing the vigor of cyclic adenosine monophosphate diesterase, increases cyclic adenosine monophosphate level and realizes.Radix Scutellariae bitter in the mouth is cold in nature, enters lung, the heart, gallbladder, large intestine channel, has heat clearing and damp drying, eliminating fire and detoxication, antiabortive function, and fever disease in summer vomiting uncomfortable in chest, cough due to lung-heat, bleeding due to blood-heat, high hot excessive thirst, damp-heat diarrhea etc. are had to good efficacy.Modern study proves, Radix Scutellariae is mainly containing baicalin, baicalin, wogonin, the compositions such as wogonoside, neobaicalein, cupreol.Its antimicrobial spectrum is wider, and to various bacteria, microorganism has inhibitory action.The effects such as Radix Scutellariae also has blood pressure lowering, calmness, diuresis, protects the liver, function of gallbladder promoting, antiallergic, releasing smooth muscle spasm, antioxidation.Fructus Corni, sour, puckery, tepor.Return liver, kidney channel.There is liver and kidney tonifying, essence astringing and desertion stemming.Fructus Corni tepor and not hot, is the medicine of flat nourishing YIN sun simply, though the deficiency of YIN or yang deficiency, all can adapted.It can liver and kidney tonifying, can restrain again astringent or styptic treatment for spontaneous sweating; Energy complementary energy is puckery, is its another feature.The newly organized > > of < < book on Chinese herbal medicine carries: " medicine of nourishing YIN does not have cloth sheet; also only cornel large invigorating the liver and kidney in mountain is specially and not assorted for victor; both partially without cold and heat, without the back of the body of negative and positive, real is the hat of all nourishing YINs again." it contains cornin, the not multiple active ingredient such as the iridoid glycosides such as sieve glycoside, Cornuside, sweroside, loganin and Saponin, ursolic acid, tartaric acid, gallic acid, malic acid, Fructus Corni tannin.There are obvious diuresis, blood pressure lowering, the antibacterial and leukocytic effect of elevating blood, treatment deficiency of both the liver and kidney, deficiency of kidney yin are had to obvious curative effects.Fructus Corni is for deficiency of the liver and kindey, the compatibilities such as normal and Radix Rehmanniae Preparata, Fructus Lycii, the Radix Paeoniae Alba.
Full side's compatibility is rigorous, and all medicines coordinate, and QI and blood also turns round and look at, and replenishing QI to invigorate the spleen is to consolidate void, and treating both the principal and secondary aspects of a disease, brings out the best in each other.
Each raw material of the present invention also can according to the form below the embodiment that mixes of listed part by weight realize.Its processing technique is identical with embodiment 1.(unit: gram)
Below in conjunction with my institute, the clinical trial that Wendeng City, In Shandong Weihai central hospital carries out is done further, is described in detail the present invention:
(1) case selection: 1 day～2011 May in 2008, on December 1, and 120 examples are diagnosed as Parkinsonian and include this observation in, 45～78 years old age, male 68 examples wherein, female's 52 examples, the course of disease 0.5 to 25 year.PD inclusion criteria: (1) is through having the neurosurgeon of clinical experience according to the Parkinson disease of Britain's think-tank diagnosis of Parkinson disease standard diagnostics; (2) through the patient of regular Drug therapy; (3) all patients all " open " stage in Drug therapy.Exclusion standard: (1) eliminating is secondary to the parkinson's syndrome due to cerebrovascular disease, wound and other nerves, mental sickness; (2) parkinson supraposition syndrome; (3) suffers from the patient of malignant tumor, deformity and other body serious diseases; (4) in Drug therapy " pass " stage.
(2) the standard of curative effect evaluation: evaluation criteria: the motor symptoms order of severity of unifying marking scales (UPDRS) III part and Hoehn-Yahr grading scale assess patient with PD.The activity of daily living of unifying marking scales (UPDRS) part ii and activity of daily living questionnaire (ADCS-ADL) assess patient with PD.With PD, unify marking scales (UPDRS) part i assess patient spirit, behavior and emotion.Application simple intelligent scale (MMSE) is as screening means, and Montreal Cognitive Assessment (MOCA) is evaluated mild cognition impairment.Fuld object test of memory (FOM) evaluation short term memory, Verbal fluency test (RVR) evaluation long term memory and language function; Block design test (BD) evaluation space structure ability; Digit span test (DS) evaluation is noted and moment memory.Depression and anxious state by Hamilton depressive scale (HRSD) and Hamilton anxiety scale (HAMA) assess patient.
(3) Therapeutic Method: every bu morning, noon and afternoon 3 times are oral, each approximately 60 milliliters of warm medicine soup (medicine) being taken before meal use, 30 days per courses for the treatment of.Totally 3 courses for the treatment of.Having heating, cranium presses the Sx persons such as high, severe infections, hypertension, diabetes to give respective handling.120 routine PD patients are divided into treatment group 60 example and placebo group 60 examples at random.Wherein treatment group is taken above-mentioned Chinese medicine decoction, and matched group is taken placebo, and all take the Western medicine such as madopar for two groups is Primary Care.Respectively at treatment, within latter 1 month, 3 months and 6 months, evaluate.
(4) therapeutic effect:
1, spirit, behavior and emotion (UPDRS-I) scoring: treatment group is after treatment, and spirit, behavior and emotion integration have clear improvement compared with matched group, and statistics has significant (P < 0.05), in Table 1.
2, activities of daily living (UPDRS-II) scoring: treatment group is after treatment, and activities of daily living integration has clear improvement compared with matched group, and statistics has significant (P < 0.05), in Table 2.
3, motor function inspection (UPDRS-III) scoring: treatment group is after treatment, and motor function checks that integration has clear improvement compared with matched group, and statistics has significant (P < 0.05), in Table 3.
4, motor complication (UPDRS-IV) scoring: treatment group is after treatment, and motor complication integration has clear improvement compared with matched group, and statistics has significant (P < 0.05), in Table 4.
5, life satisfaction degree (LSIB) scoring: treatment group is after treatment, and life satisfaction degree integration has clear improvement compared with matched group, and statistics has significant (P < 0.05), in Table 5.
6, parkinson disease quality of life marking scales (PDQ) scoring: treatment group is after treatment, parkinson disease quality of life marking scales integration has clear improvement compared with matched group, statistics has significant (P < 0.05), in Table 6.
Table 1 spirit, behavior and emotion (UPDRS-I) scoring is (x ± s, n=60) relatively
Note: compare with matched group
(table 2～6 are same)
Table 2 activities of daily living (UPDRS-II) scoring is (x ± s, n=60) relatively
Table 3 motor function inspection (UPDRS-III) scoring is (x ± s, n=60) relatively
Table 4 motor complication (UPDRS-IV) scoring is (x ± s, n=60) relatively
Table 5 life satisfaction degree (LSIB) scoring is (x ± s, n=60) relatively
Table 6 parkinson disease quality of life marking scales (PDQ) scoring is (x ± s, n=60) relatively
Claims (1)
1. treat Parkinsonian Chinese medicine decoction for one kind, it is characterized in that the weight portion that crude drug forms is: the Radix Paeoniae Alba 17～22, Radix Rehmanniae Preparata 13～17, Radix Angelicae Sinensis 17～22, Radix Glycyrrhizae 13～17, Fructus Lycii 17～22, the Radix Astragali 17～22, Carapax et Plastrum Testudinis 13～17, the Radix Polygoni Multiflori 17～22, Ramulus Uncariae Cum Uncis 22～28, Rhizoma Gastrodiae 13～17, Scorpio 3～7, Radix Salviae Miltiorrhizae 13～17, Radix Scutellariae 8～12, Fructus Corni 8～12, Cornu Saigae Tataricae powder 1～2, by the above-mentioned Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Carapax et Plastrum Testudinis, the Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Rhizoma Gastrodiae, Scorpio, Radix Salviae Miltiorrhizae, Radix Scutellariae, Fructus Corni crude drug is soaked in water after mixing, the filtrate of removing slag after decocting to obtain, after being pulverized, Cornu Saigae Tataricae mixs homogeneously with described filtrate.
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| CN113476558B (en) * | 2021-07-15 | 2022-10-04 | 湖南中医药大学 | Traditional Chinese medicine composition, traditional Chinese medicine preparation and traditional Chinese medicine product for treating Parkinson's disease |
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Effective date of registration: 20151223 Address after: 130000, 1 overseas street, Jilin, Changchun Patentee after: Changchun Haiwai Pharmaceutical(Group) Co., Ltd. Address before: 264400 Wendeng, Shandong, Zhejiang Province, East Hill Road, No. 3, Wendeng Central Hospital, Weihai Patentee before: Li Zhenguang |