CN100457166C - Chinese medicinal preparation for treating viral influenza - Google Patents
Chinese medicinal preparation for treating viral influenza Download PDFInfo
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- CN100457166C CN100457166C CNB2006100422117A CN200610042211A CN100457166C CN 100457166 C CN100457166 C CN 100457166C CN B2006100422117 A CNB2006100422117 A CN B2006100422117A CN 200610042211 A CN200610042211 A CN 200610042211A CN 100457166 C CN100457166 C CN 100457166C
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Abstract
The invention provides a traditional Chinese medicinal composition for treating virus common cold, which is prepared from the following medicinal herbs (by weight portions): honeysuckle flower 15-45 parts, dandehon herb 20-60 parts, root of balloonflower 5-20 parts, Chinese ephedra 5-20 parts, bitter apricot kernel 5-25 parts, calcium sulphate 20-40 parts, licorice root 1-10 parts, radix isatidis 20-40 parts, bamboo leaf 5-20 parts, mulberry leaf 5-28 parts, purple perilla 5-26 parts, herba schizonepetae 6-2 parts, arctium fruit 8-25 parts, flitilarry bulb 4-25 parts, reed rhizome 22-40 parts, and red peony root 7-30 parts.
Description
1, technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of Chinese medicine preparation for the treatment of viral influenza and preparation method thereof.
2, background technology
Immanent cause, along with the blue-collar minimizing of the improvement of people's living environment, cause people's resistance against diseases obviously to descend, external factor is along with industrial expansion, the increase of the aggravation of atmospheric pollution level, population residential density, accelerated the propagation of various pathogenic bacteria viruses, increased of the infringement of various pathogenic bacteria viruses people.With the viral influenza is example, the quantity that present people have virus flu increases than having former years significantly, and the medicine resistance ability of virus also is significantly improved, in the therapeutic process of viral influenza except dosage obviously increases, significantly descending appears in the therapeutic effect of some medicine, and some does not have effect basically.Also do not treat the specific drug of viral influenza treatment for now.
3, summary of the invention
The special effect Chinese preparation that the purpose of this invention is to provide a kind of special for treating viral influenza.This Chinese medicine preparation carries out the science compatibility by Flos Lonicerae, Herba Taraxaci, Radix Platycodonis, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, Radix Isatidis, Herba Lophatheri, Folium Mori, Folium Perillae, Herba Schizonepetae, Fructus Arctii, Bulbus Fritillariae Thunbergii, Rhizoma Phragmitis, Radix Paeoniae Rubra 15 flavor raw material of Chinese medicine according to the ultimate principle of Chinese medicine and pharmacy and traditional Chinese medical science secret recipe handed down from one's ancestors and forms.
[side separates]
The card that we are controlled is that exopathogen is not understood heat-transformation in going into.So with the cold and cool diaphoretic medicine of big agent separating pathogenic factor in the exterior, the heat clearing away poison, sweet cold with Flos Lonicerae in the side, fragrance is evacuated, the kind lung meridian pathogenic heat of loosing, the gastric heat that clears away heart-fire poison is a monarch drug, supplement to the Herbal: call its " main pyretic toxicity ... dense decoction it." the Herba Taraxaci hardship is with drop-down, and is sweet with detoxifcation, the cold gas that stagnates that looses of can heat clearing away holding concurrently is for the good merchantable brand of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation is a ministerial drug; Radix Isatidis " classification medical herbs " is called it: " separate all malicious malignant boil, diffusing poison reduces internal heat, " is assistant, and the three plays heat-clearing and toxic substances removing altogether, the dispelling wind eliminating stagnation, and all the other are for making.Fang Zhongwu is with MAXINGSHIGAN TANG, with Herba Ephedrae Xin Ganwen, depressed lung-energy dispersing; Because of the intenseness of heat impairment of YIN, so reuse Gypsum Fibrosum hot sweet Great Cold, the heat of letting out the lung stomach clearly is to promote the production of body fluid, and the two assists last three medicines, declares sharp lung qi and does not help heat, removing summer-heat pathogenic heat and not cool holding back; Sharp lung qi falls in the Semen Armeniacae Amarum bitter in the mouth, and phase factor falls in a surname with Herba Ephedrae, and it is then clear respectful collaborative to close Gypsum Fibrosum; And with the Radix Paeoniae Rubra clearing away heat and cooling blood blood system of joining the army, Radix Glycyrrhizae is in harmonious proportion between cold and heat a surname falls.
Contain in the pathogenic heat, for a long time must impairment of YIN, with the sweet cold light weight of Rhizoma Phragmitis, clear saturating lung gastric qi is divided excess-heat, and can YIN nourishing and the production of body fluid promoting, the relieving restlessness of quenching the thirst has diuretic actions again simultaneously, can strengthen the effect of Herba Taraxaci eliminating damp-heat, make evil under go out.
The hot hardship of loosing of Fructus Arctii is let out, cold can heat clearing away, let out clearly and loose, can dispelling wind and heat pathogens, the expelling heat from the exterior pyretic toxicity, this product is arduous cold in nature, the property of falling is clearly arranged in rising among floating again, the wind heat of loosing outward, in the poison that expels the heat-evil, and property is sliding partially sharp, but double tonneau two just, helping adds medicine to makes pathogenic heat descending; The Bulbus Fritillariae Thunbergii bitter cold is fallen and is let out many poison that can hardship expel the heat-evil, the dissipating depression of QI eliminating stagnation, supplementary Amplifications of the Compendium of Materia Medica: " the sharp expectorant that detoxifies is opened lung qi dispersing gas, all lungs man folder fire has expectorant person suitable this." select for use medicine light weights such as Radix Platycodonis, Herba Lophatheri, Folium Mori, Folium Perillae, Herba Schizonepetae up in the side, with the pathogenic heat of Xie Zaibiao, make evilly from cure by diaphoresis, and the logical lung qi of being held back resistance of a surname is arranged;
The long memorial wind heat radiation altogether of full side, the effect of YIN nourishing detoxifcation makes pathogenic heat to separate, cloudy liquid must be answered.
The noisy lung of [function cures mainly] heat clearing away, the sore-throat relieving of relievining asthma.Be used for the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, contain in the evil poison, fever with chills, headache, the nasal obstruction watery nasal discharge, mouthfeel is silent, laryngopharynx swelling and pain, general fatigue is unable, aches all over inappetence.Modern times are used for influenza clinically, and viral influenza comprises bird flu, the clinical viral disease of still not having effective treatment means of modern times such as SARS.
The traditional Chinese medical science is thought: the infectious disease in the modern times is similar to pestilence: the cause of disease " the non-cold non-summer-heat of non-wind is non-wet, is not have a kind of unusual pathogen to feel in this world ", the route of transmission of pestilence is to go into from mouth and nose.The traditional Chinese medical science is thought: summer-heat consumes the Tianjin of feeling frustrated, and method of treatment commonly used is: bitter cold is unloaded the fire dehumidifying, sweet cool pathogenic heat, the sweet cool clearing heat and moistening dryness method removed.
The present invention is the special effect Chinese preparation of special for treating viral influenza, and full side's compatibility is proper, receives heat-clearing and toxic substances removing altogether, the merit of relieving sore throat and diminishing swelling.Be used for viral influenza and both can have brought into play stronger anti-Seedling, antivirus action, can significantly improve its clinical symptoms again.Be used for the sore throat due to the exuberant lung-stomach heat, disease sees that pharyngalgia is acute, dysphagia, thirsty polydipsia, cough, thick sputum, heating; oliguria with reddish urine is hard and dry, and is pharyngeal scarlet; or see the pharyngeal tonsils redness; there are yellow-white pus point, red tongue, yellow and thin fur in the surface; rapid pulse reaches the above disease person that acute/chronic pharyngitis, tonsillitis etc. cause effectively, all has obvious curative effects.
Antiviral through this product is carried out, experimental studies results analgesic, that ease pain, press down Seedling, antiinflammatory action show: 1. this product is inhibited to external pathological changes caused by virus, and the B-mode cold virus of first type is all had the obvious suppression effect; 2. can reduce the rabbit body temperature that is caused by absorption whooping cough bacterin-toxoid mix preparation raises: 8. the mice vola pain that hot plate method is caused has obvious analgesic activity, can significantly reduce the mouse writhing reaction times, improve the mice threshold of pain: 4. to Pseudomonas aeruginosa, the staphylococcus aureus of In vitro culture, the pharyngeal common pathogenic bacterium in eight kinds of oral cavities such as Klebsiella pneumonia have inhibitory action in various degree, and bacteriostatic test can obviously reduce mouse death rate in the body; 5. the outer test of this crystal shows that this product has tangible anti-endotoxin, blocking-up or suppress its pathological effect and 6. can suppress rat toes swelling due to the 5-HT, and can obviously suppress histamine phosphate's induced mice capillary and manage permeability fully and increase and the subcutaneous experimental chronic granuloma of the caused rat back of agar.According to (Pharmacopoeia of People's Republic of China, the relevant form and the requirement of version in 2005 are carried out fourth research to this particulate character, discriminating, inspection and assay etc., all meet the requirements.According to " Pharmacopoeia of People's Republic of China) relevant requirements of 2005 years versions, stability to this product is studied, investigated accelerated test and the room temperature projects such as investigation that keep sample, checked that aspects such as appearance character, discriminating, moisture, granularity, melting, content, health examination all do not have significant change.
In order to show the therapeutic effect of granule of the present invention, the present invention has carried out clinical observation to the patient that 200 examples have the viral influenza symptom after diagnosing, and its concrete outcome is:
The clinical observation of treatment viral influenza: according to through making a definite diagnosis the patient 200 example statistics of suffering from viral influenza, male's 70 examples wherein, women's 130 examples, age reckling 7 years old, the maximum 68 years old, 7-16 year 34 examples, 17-25 year 56 examples, 26-35 year 44 examples, 36-46 year 20 examples, 46-62 year 26 examples;
Efficacy evaluation:
Instructions of taking: every bag 10-15g, the 1-2 bag/time, every day three times.
In the medication 3 days, ache all over, headache, dry pharynx, pharyngalgia alleviate, and 5 days disappear with interior above-mentioned symptom is recovery from illness: a transference cure is arranged is produce effects with interior for medication 5 days; Medication 5 days makes moderate progress effectively before than medication with interior all symptoms; It is invalid that medication obviously was not improved as with interior symptom in 5 days:
Below be that medication 5 days is with interior curative effect statistics;
Recovery from illness produce effects enabledisable total effective rate %
Ache all over 164 12 16 8 99
Have a headache 84 4 12 12 93.8
Have sore throat 116 8 10 6 95.7
Generate heat 84 646 94
Cough 110 16 40 100
By last table as can be seen: oral liquid of the present invention can reach 93.8%～100% for the main clinic symptoms sign treatment total effective rate of viral influenza.
4, embodiment
The special effect Chinese preparation that the purpose of this invention is to provide a kind of special for treating viral influenza is to be made by the medicine of following weight proportion:
Flos Lonicerae 15-45 part Herba Taraxaci 20-60 part Radix Platycodonis 5-20 part
Herba Ephedrae 5-20 part Semen Armeniacae Amarum 5-25 part Gypsum Fibrosum 20-40 part
Radix Glycyrrhizae 1-10 part Radix Isatidis 20-40 part Herba Lophatheri 5-20 part
Folium Mori 5-28 part Folium Perillae 5-26 part Herba Schizonepetae 6-25 part
Fructus Arctii 8-25 part Bulbus Fritillariae Thunbergii 4-25 part Rhizoma Phragmitis 22-40 part
Radix Paeoniae Rubra 7-30 part.
The preparation process of Chinese medicine preparation of the present invention is as follows:
Granule, tablet or capsular preparation:
1) take by weighing in proportion, Fructus Arctii, Bulbus Fritillariae Thunbergii, Radix Paeoniae Rubra and Radix Isatidis, the 60%-90% ethanol extraction of doubly measuring with 6-15 3 times, medicinal residues (1) leach standby, and it is standby that merge extractive liquid,, decompression recycling ethanol, extracting solution are condensed into thick extractum (a);
2) take by weighing Folium Perillae and Herba Schizonepetae in the prescription ratio and add the water logging bubble 0.5 hour that 6-15 doubly measures, decocted 4-6 hour, it is standby to collect steam condensation extraction volatile oil (2), and decocting liquid and medicinal residues (3) are standby;
3) the water logging bubble that medicinal residues (1), decocting liquid and medicinal residues (3), Flos Lonicerae, Herba Taraxaci, Radix Platycodonis, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, Herba Lophatheri, Folium Mori, Rhizoma Phragmitis adding 6-15 are doubly measured is 1 hour, heating decocts 2 times, each 2 hours, filtered while hot, merge filtrate twice, concentrating under reduced pressure is dried to thick extractum (b);
4) thick extractum (a) and thick extractum (b) stir with an amount of conventional adjuvant of volatile oil merging interpolation and send comminutor or tablet machine molding to make pharmaceutics described granule, tablet or capsule.
The preparation of oral liquid: thick extractum (a) and thick extractum (b) and volatile oil merge and add appropriate amount of deionized water and suitable conventional adjuvant diluted mixture is even, make the above oral liquid of pharmaceutics through the filling bottle packaging sterilizing.
The special effect Chinese preparation of purpose special for treating viral influenza of the present invention can also be to be made by the medicine of following weight proportion:
12 parts of 35 parts of Radix Platycodoniss of 25 parts of Herba Taraxacis of Flos Lonicerae
28 parts in 20 parts of Gypsum Fibrosum of 15 portions of Semen Armeniacae Amarums of Herba Ephedrae
13 parts of 26 portions of Herba Lophatheris of 7 parts of Radix Isatidis of Radix Glycyrrhizae
15 parts of 8 portions of Herba Schizonepetae of 13 parts of Folium Perillaes of Folium Mori
28 parts of 20 parts of Rhizoma Phragmitiss of 16 parts of Bulbus Fritillariae Thunbergiis of Fructus Arctii
18 parts of Radix Paeoniae Rubra,
Embodiment 1:
Prescription
Flos Lonicerae 30g, Herba Taraxaci 30g, Radix Platycodonis 10g, Herba Ephedrae 6g, Semen Armeniacae Amarum 10g, Gypsum Fibrosum 30g, Radix Glycyrrhizae 3g, Radix Isatidis 30g, Herba Lophatheri 10g, Folium Mori 10g, Folium Perillae 10g, Herba Schizonepetae 10g, Fructus Arctii 12g, Bulbus Fritillariae Thunbergii 10g, Rhizoma Phragmitis 30g, Radix Paeoniae Rubra 15g.
Granule, tablet and capsular preparation:
1) take by weighing in proportion, Fructus Arctii, Bulbus Fritillariae Thunbergii, Radix Paeoniae Rubra and Radix Isatidis, the 60%-90% ethanol extraction of doubly measuring with 6-15 3 times, medicinal residues (1) leach standby, and it is standby that merge extractive liquid,, decompression recycling ethanol, extracting solution are condensed into thick extractum (a);
2) take by weighing Folium Perillae and Herba Schizonepetae in the prescription ratio and add the water logging bubble 0.5 hour that 6-15 doubly measures, decocted 4-6 hour, it is standby to collect steam condensation extraction volatile oil (2), and decocting liquid and medicinal residues (3) are standby;
3) the water logging bubble that medicinal residues (1), decocting liquid and medicinal residues (3), Flos Lonicerae, Herba Taraxaci, Radix Platycodonis, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, Herba Lophatheri, Folium Mori, Rhizoma Phragmitis adding 6-15 are doubly measured is 1 hour, heating decocts 2 times, each 2 hours, filtered while hot, merge filtrate twice, concentrating under reduced pressure is dried to thick extractum (b);
4) thick extractum (a) and thick extractum (b) stir with an amount of conventional adjuvant of volatile oil merging interpolation and send comminutor or tablet machine molding to make pharmaceutics described granule, tablet or capsule.
The preparation of oral liquid:
Thick extractum (a) and thick extractum (b) and volatile oil merge and add appropriate amount of deionized water and the dilution of conventional proper auxiliary materials, make the above oral liquid of pharmaceutics through the filling bottle packaging sterilizing.
Embodiment 2
Prescription
Flos Lonicerae 35g, Herba Taraxaci 25g, Radix Platycodonis 15g, Herba Ephedrae 10g, Semen Armeniacae Amarum 15g, Gypsum Fibrosum 25g, Radix Glycyrrhizae 6g, Radix Isatidis 35g, Herba Lophatheri 15g, Folium Mori 15g, Folium Perillae 15g, Herba Schizonepetae 8g, Fructus Arctii 15g, Bulbus Fritillariae Thunbergii 15g, Rhizoma Phragmitis 25g, Radix Paeoniae Rubra 15g.
Preparation method is identical with embodiment 1.
Embodiment 3
Prescription
Flos Lonicerae 15g, Herba Taraxaci 20g, Radix Platycodonis 10g, Herba Ephedrae 6g, Semen Armeniacae Amarum 7g, Gypsum Fibrosum 20g, Radix Glycyrrhizae 3g, Radix Isatidis 30g, Herba Lophatheri 9g, Folium Mori 12g, Folium Perillae 12g, Herba Schizonepetae 11g, Fructus Arctii 13g, Bulbus Fritillariae Thunbergii 17g, Rhizoma Phragmitis 26g, Radix Paeoniae Rubra 23g.
Preparation method is identical with embodiment 1.
Embodiment 4
Flos Lonicerae 15g, Herba Taraxaci 20g, Radix Platycodonis 5g, Herba Ephedrae 5g, Semen Armeniacae Amarum 5g, Gypsum Fibrosum 20g, Radix Glycyrrhizae 2g, Radix Isatidis 20g, Herba Lophatheri 5g, Folium Mori 5g, Folium Perillae 5g, Herba Schizonepetae 6g, Fructus Arctii 8g, Bulbus Fritillariae Thunbergii 5g, Rhizoma Phragmitis 22g, Radix Paeoniae Rubra 8g.
Preparation method is identical with embodiment 1.
Embodiment 5
Flos Lonicerae 40g, Herba Taraxaci 55g, Radix Platycodonis 15g, Herba Ephedrae 18g, Semen Armeniacae Amarum 23g, Gypsum Fibrosum 33g, Radix Glycyrrhizae 8g, Radix Isatidis 36g, Herba Lophatheri 16g, Folium Mori 18g, Folium Perillae 16g, Herba Schizonepetae 18g, Fructus Arctii 22g, Bulbus Fritillariae Thunbergii 23g, Rhizoma Phragmitis 33g, Radix Paeoniae Rubra 26g.
Embodiment 6
Prescription
Flos Lonicerae 25g, Herba Taraxaci 35g, Radix Platycodonis 12g, Herba Ephedrae 15g, Semen Armeniacae Amarum 20g, Gypsum Fibrosum 28g, Radix Glycyrrhizae 7g, Radix Isatidis 26g, Herba Lophatheri 13g, Folium Mori 13g, Folium Perillae 8g, Herba Schizonepetae 15g, Fructus Arctii 16g, Bulbus Fritillariae Thunbergii 20g, Rhizoma Phragmitis 28g, Radix Paeoniae Rubra 18g.
Model case (granule, tablet or capsule)
Case one: Lee XX, the man 26 years old, catches a cold headache, heating, 38.8 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain, general fatigue is unable, is viral influenza on inspection, take we after 3 days, head does not have significant discomfort, and body temperature recovers normal for 37.2 ℃, and nose does not have sense of discomfort, and laryngopharynx swelling and pain disappears.
Case two: king XX, the woman, 17 years old, catch a cold, rhinorrhea, sneeze is obvious, 38.7 ℃ of body temperature, nasal obstruction, pharyngalgia is lighter, aches all over, and inappetence is viral influenza on inspection, take we after 3 days, nasal mucus disappears, and body temperature recovers normal for 37.0 ℃, and laryngopharynx swelling and pain disappears, and whole body does not have sense of discomfort.
Case three: Cao XX, the man, 42 years old, catch a cold, headache, heating, 38.0 ℃ of body temperature, nasal obstruction, rhinorrhea is a viral influenza on inspection, takes we after 5 days, and head does not have significant discomfort, and body temperature recovers normal for 37.1 ℃, and nasal obstruction, nasal mucus disappear.
Case four: open XX, man, 13 years old, catch a cold headache, heating, 38.5 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain, hoarseness is a viral influenza on inspection, takes we after 3 days, head does not have significant discomfort, and body temperature recovers normal for 37.1 ℃, and nose does not have sense of discomfort, laryngopharynx swelling and pain disappears, and it is normal that sound recovers, and physical recovery is normal.
Case five: woods XX, the woman 21 years old, catches a cold headache, heating, 38.8 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain through verifying as viral influenza, is taken we after 3 days, head does not have significant discomfort, and body temperature recovers normal for 37.2 ℃, and nose does not have sense of discomfort, and laryngopharynx swelling and pain disappears, and physical recovery is normal.
Case six: Korea Spro XX, the man 30 years old, catches a cold, headache, heating, 38.9 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain, hoarseness, slight cough, be viral influenza on inspection, take we after 5 days, head does not have significant discomfort, body temperature recovers normal for 36.9 ℃, and nose does not have sense of discomfort, and laryngopharynx swelling and pain disappears, it is normal that sound recovers, and cough disappears, and physical recovery is normal.
Case seven: woods XX, the woman 26 years old, catches a cold, headache, heating, 39.1 ℃ of body temperature, nasal obstruction, snivel, laryngopharynx swelling and pain, hoarseness, cough, feeling run-down, is viral influenza on inspection, takes we after 5 days, and head does not have significant discomfort, body temperature recovers normal for 37.1 ℃, and nose does not have sense of discomfort, no nasal mucus, and laryngopharynx swelling and pain disappears, it is normal that sound recovers, and cough disappears, and physical recovery is normal.
Case eight: village XX, the woman 50 years old, catches a cold, headache, heating, 38.5 ℃ of body temperature, nasal obstruction, snivel, hoarseness, cough is ached all over, be viral influenza on inspection, take we after 4 days, head does not have significant discomfort, and body temperature recovers normal for 36.8 ℃, nose does not have sense of discomfort, and laryngopharynx swelling and pain disappears, no nasal mucus, it is normal that sound recovers, and cough disappears, and physical recovery is normal.
Case nine: southern XX, the man 22 years old, catches a cold, headache, heating, 39.2 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain, hoarseness, slight cough is a viral influenza on inspection, takes we after 5 days, head does not have significant discomfort, and body temperature recovers normal for 36.9 ℃, and nose does not have sense of discomfort, laryngopharynx swelling and pain disappears, and it is normal that sound recovers, and cough disappears.
Case ten: open XX, the woman 25 years old, catches a cold, headache, heating, 39.1 ℃ of body temperature, nasal obstruction, laryngopharynx swelling and pain, hoarseness, slight cough, eye conjunctiva mild hyperaemia, take GANKANG, after injection of antibiotics is invalid, take we after 3 days, head does not have significant discomfort, and body temperature recovers normal for 36.7 ℃, and nasal obstruction disappears, it is normal that sound recovers, the cough transference cure, and the eye conjunctiva does not have hyperemia.
Claims (1)
1, a kind of Chinese medicine preparation for the treatment of viral influenza is characterized in that it is to be made by the medicine of following weight proportion:
Flos Lonicerae 15-45 part Herba Taraxaci 20-60 part Radix Platycodonis 5-20 part
Herba Ephedrae 5-20 part Semen Armeniacae Amarum 5-25 part Gypsum Fibrosum 20-40 part
Radix Glycyrrhizae 1-10 part Radix Isatidis 20-40 part Herba Lophatheri 5-20 part
Folium Mori 5-28 part Folium Perillae 5-26 part Herba Schizonepetae 6-25 part
Fructus Arctii 8-25 part Bulbus Fritillariae Thunbergii 4-25 part Rhizoma Phragmitis 22-40 part
Radix Paeoniae Rubra 7-30 part, preparation process is as follows:
1) take by weighing Fructus Arctii, Bulbus Fritillariae Thunbergii, Radix Paeoniae Rubra and Radix Isatidis in proportion, the 60%-90% ethanol extraction of doubly measuring with 6-15 3 times, medicinal residues 1 leach standby, and it is standby that merge extractive liquid,, decompression recycling ethanol, extracting solution are condensed into thick extractum a;
2) take by weighing Folium Perillae and Herba Schizonepetae in the prescription ratio and add the water logging bubble 0.5 hour that 6-15 doubly measures, decocted 4-6 hour, it is standby to collect steam condensation extraction volatile oil 2, and decocting liquid and medicinal residues 3 are standby;
3) with medicinal residues 1, the step 2 of step 1)) decocting liquid and Flos Lonicerae, Herba Taraxaci, Radix Platycodonis, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Radix Glycyrrhizae, Herba Lophatheri, Folium Mori and Rhizoma Phragmitis in medicinal residues 3 and the prescription add the water logging bubble 1 hour that 6-15 doubly measures, heating decocts 2 times, each 2 hours, filtered while hot, merge filtrate twice, concentrating under reduced pressure is dried to thick extractum b;
4) with the thick extractum a of step 1) and the thick extractum b and the step 2 of step 3)) volatile oil 2 merge, add an amount of conventional adjuvant and stir and send comminutor or tablet machine molding to make pharmaceutics described granule, tablet or capsule.
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| CNB2006100422117A CN100457166C (en) | 2006-01-23 | 2006-01-23 | Chinese medicinal preparation for treating viral influenza |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101708275B (en) * | 2009-11-27 | 2012-11-28 | 北京市卫生局临床药学研究所 | Chinese medicament for treating flu caused by influenza A(H1N1) and the like |
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| CN101337062B (en) * | 2008-08-11 | 2010-09-29 | 李翠华 | Traditional Chinese medicine composition for treating tonsillitis |
| CN101926908B (en) * | 2010-08-21 | 2012-05-23 | 张晓玲 | Chinese medicinal composition for treating cold |
| CN102526665B (en) * | 2012-01-17 | 2013-08-14 | 刘木生 | Chinese medicinal particles for clearing heat, allaying fever and treating cold |
| CN103446377B (en) * | 2013-07-26 | 2015-07-15 | 杨德俊 | Traditional Chinese medicine composition for treating viral influenza |
| CN104138541B (en) * | 2014-07-31 | 2017-07-11 | 韦宁香 | Prevent and treat the Chinese medicine preparation and its production method of cobra respiratory disease |
| CN105902576A (en) * | 2016-04-29 | 2016-08-31 | 罗佳 | Viral influenza treating composition and preparation method and application thereof |
| CN107343928A (en) * | 2016-05-07 | 2017-11-14 | 李海珍 | A kind of Chinese medicine composition for preventing and treating bird flu |
| CN106138843A (en) * | 2016-08-25 | 2016-11-23 | 陈鹏举 | A kind of Chinese medicine composition treating bird flu |
| CN106138842A (en) * | 2016-08-25 | 2016-11-23 | 陈鹏举 | A kind of Chinese medicine composition treating avian paramyxoviruses disease |
| CN111888413B (en) * | 2020-09-18 | 2022-07-12 | 天津中医药大学 | Pharmaceutical composition for autumn respiratory diseases |
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