CN1335174A - Stomatopathy and throat disease treating health care medicine and its production process - Google Patents
Stomatopathy and throat disease treating health care medicine and its production process Download PDFInfo
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Abstract
The health care medicine for treating stomatopathy and throat disease is prepared with nine Chinese medicinal materials including honeysuckle, chrysanthemum, Radix isatidis, Herba Hedyotis Diffusae, balloonflower root, etc. and through washing, crushing, 200 mesh sieving and other steps to obtain oral liquid, lozenge, tablet, capsule or bolus. The health care medicine can eliminate inflammation caused by various evil, and treat oral cavity and throat diseases, such as laryngopharyngitis, tonsillitis, ulcer of oral cavity and gingivitis as well as upper respiratory tract infection.
Description
Technical field
The present invention relates to a kind of Chinese medicine and production method thereof for the treatment of oral cavity and laryngopharyngeal diseases such as pharyngolaryngitis, tonsillitis, oral ulcer, gingivitis, upper respiratory tract infection.
Background technology
Oral cavity and laryngopharyngeal diseases are human commonly encountered diseases, high morbidity, its main cause has multiple, wherein great majority are the intestines and stomach intenseness of heat, retention of heat in the spleen and stomach causes, be embodied in oral ulcer, red swelling and pain of throat or fester, the tonsil inflammation, red swelling of gingiva, hemorrhage, the dry tongue halitosis, got gently dysphagia then of these sick patients, heavy then hyperpyrexia is had a headache, routine work and life have been influenced, for these treatment of conditions, doctor trained in Western medicine is mainly taked eliminating inflammation and expelling toxin medicine for oral administration at present, antibiotics, or injection penicillin, erythromycin, the treatment of antibiotic medicine such as cephalo ammonia Bian, the traditional Chinese medical science mainly adopts has heat-clearing and toxic substances removing, the medicine of removing heat from blood lung heat clearing is treated, as Flos Lonicerae, Fructus Forsythiae, Herba Violae, Fructus Canarii, Rhizoma Imperataes etc. have also been sold some in the market and have been treated the Chinese medicine preparation or the buccal tablet of laryngopharyngeal diseasess, as Herba Pileae Scriptae Tabellae, watermelon crystal, JINSANGZIHOUBAO etc., these Chinese medicine preparation have played certain effect to slowing down some throat disease, but great majority only play the effect that palliates a disease, and can not cure the heavier patient of the state of an illness internally quickly, suffer from throat, the oral cavity critically ill patient must rely on heavy dose of antibiotics western medicine, and heavy dose of bacteriophage on human body produces some side effect to a certain extent.
In recent years, public publication is as " Chinese medicine ", and " Chinese herbal medicine " waits the medicine of also reporting many treatments oral cavity and laryngopharyngeal diseases on some magazines, Chinese patent 94112228 discloses with Radix Platycodonis, Radix Glycyrrhizae, Flos Lonicerae, Flos Chrysanthemi, Herba Menthae, FRUCTUS TERMINALIAE IMMATURUS or semen sterculiiae lychnophorae, green tea, Gan Yeju are that the Chinese medicine bag of Main Ingredients and Appearance is made tea, to the treatment pharyngalgia, hoarseness has certain effect; Chinese patent 97111786 also discloses a kind of cleaning throat and moistening larynx eliminating inflammation and expelling toxin beverage, form by Fructus Crataegi, Flos Chrysanthemi, Fructus Lycii, Flos Lonicerae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae and Mel or white sugar, pure water, can heat-clearing and toxic substances removing, cleaning throat and moistening larynx, play certain antiinflammatory, antidotal purpose.
The treatment oral cavity of selling on above-mentioned open source literature and the market and the Chinese medicine of laryngopharyngeal diseases or beverage great majority can only take stopgap measures, and can not effect a permanent cure, and particularly can not treat the state of an illness and increase the weight of, and cause headache, heating, the patient of general malaise.
Technology contents
In order to treat oral cavity and laryngopharyngeal diseases better, the inventor is from the prescription of tradition Chinese herbal treatment among the people, through discovery and arrangement, experiment repeatedly, contrast, and by modern detection and treatment means, sum up a kind of to treating common oral cavity, the Chinese herbal and crude drugs preparations of laryngopharyngeal diseases, and make with modern pharmaceutical technology, to medium-height grass treatment oral cavity, laryngopharyngeal diseases provides a kind of new good health care medicine.
The kind composition of health medicine of the present invention and content (weight) are as follows
Flos Lonicerae 10--15 (weight portion)
Flos Chrysanthemi 8--10 (weight portion)
Radix Isatidis 15--30 (weight portion)
Herba Hedyotidis Diffusae 5--10 (weight portion)
Radix Platycodonis 5--10 (weight portion)
Periostracum Cicadae 3--6 (weight portion)
Flos Ilicis Asprellae 15--30 (weight portion)
Herba Taraxaci 10--15 (weight portion)
Mel 15--20 (weight portion)
Radix Glycyrrhizae 3--6 (weight portion)
The performance and the effectiveness of above-mentioned each composition of Chinese medicine are as follows:
Flos Lonicerae (having another name called Flos Lonicerae), sweet in flavor and cold in property, effectiveness: heat-clearing and toxic substances removing, card is controlled heating, headache, pharyngalgia, dermexanthesis, dysentery etc. are according to the research of modern Chinese medicine pharmacology, Flos Lonicerae has stronger antibacterial action to dysentery bacterium, Bacillus typhi, cholera bacteria, escherichia coli, bacillus pyocyaneus, staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae, bordetella pertussis etc., bright product and mash to apply ointment or plaster and can control suppurative wound, carbuncle etc., as with Radix Et Rhizoma Rhei, Fructus Forsythiaes etc. share, and can treat tonsillitis, stomatitis, upper respiratory tract infection.
Radix Isatidis flavor property bitter cold, effectiveness heat clearing away, removing heat from blood, detoxifcation, card control that warm epidemic disease poison, rotten larynx erythema, larynx fraud swell and ache, warm malicious macule, cheek inflammation etc.According to modern pharmacological research, Radix Isatidis all has antibacterial action to Gram-negative and positive bacteria.
Flos Chrysanthemi, nature and flavor sweetness and bitterness is cold, card controls that affection due to external wind and heat, fever and headache, pyretic toxicity pent up, the carbuncle furuncle, according to modern pharmacological research, Flos Chrysanthemi has the effect of Chinese People's Anti-Japanese Military and Political College enterobacteria, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, comma bacillus, staphylococcus aureus and beta hemolytic streptococcus, fungus.
Herba Hedyotidis Diffusae, the cold of property slightly sweet flavor, cures mainly jaundice, pharyngalgia tumor, furuncle carbuncle, gonorrhea, traumatic injury, venom at effectiveness heat-clearing and toxic substances removing, diuresis of blood circulation promoting.
Radix Platycodonis, nature and flavor toil tepor, effectiveness eliminating phlegm and stopping cough, lung qi dispersing evacuation of pus, card is controlled pyretic toxicity and is stopped up swollen, lung abscess, septum pectorale completely pain, cough a lot of phlegm, the dense infections of surgery, and according to modern pharmacological research, the contained Radix Platycodonis soap of Radix Platycodonis can promote the secretion of trachea, truly has the antiinflammatory expectorant effect.
Periostracum Cicadae, nature and flavor are salty do cold, effectiveness loose wind heat clearing away, lung qi dispersing rash, spasmolytic, removing nebula to improve visual acuity., card is controlled the strongly fragrant lung of wind heat, the hoarseness of coughing, have sore throat, the strongly fragrant table of wind heat, rubella, measles, skin itching.
Herba Taraxaci, the property bitter but sweet flavor is cold, and effectiveness heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, disease are controlled hyperactivity of toxic heat, acute mastitis swells and ache, treats poison, carbuncle, conjunctival congestion and swelling pain, according to theory of Chinese medical science research, but Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Orally taken and externally is all powerful.
Flos Ilicis Asprellae, property mildly bitter flavor, little sweet cold, cure mainly influenza, fever, acute tonsillitis, pharyngolaryngitis, traumatic injury, furuncle carbuncle at effectiveness heat-clearing and toxic substances removing, the dissipating blood stasis of subsiding a swelling.
Radix Glycyrrhizae, sweet flat, the moxibustion of nature and flavor is a tepor, and effectiveness invigorating the spleen and replenishing QI, lung moistening are eliminated the phlegm, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, and card is controlled cough and asthma, throat toxic swelling, carbuncle skin infection, fire-toxin and is stopped up and stagnate.
Mel, nature and flavor are sweet flat, the effectiveness invigorating middle warmer pain relieving of moisturizing, detoxify, disease is controlled deficiency of YIN of the spleen and stomach, dryness of the intestine constipation, the dryness of the lung is thanks to cloudy and as harmonizing drug
Above-mentioned ten kinds of Chinese herbal medicine all are heat and toxic materials clearing away medicine, and the anti-various bacteria of most of energy is to laryngopharynx swelling and pain, oral ulcer all has therapeutical effect, can take into account after they are made into comprehensively, produces synergism, curative effect is obvious, and it is applicable to acute and chronic pharyngitis, the enlargement of acute and chronic tonsillitis Jaw submental lymph nodes, oral ulcer, aphtha of the mouth and tongue, red swelling of gingiva, scorching hot dry cough in the larynx is had sore throat diseases such as upper respiratory tract infection.
Medicine of the present invention can be made preparations such as medicated powder, concentrated medicament, capsule, tablet, buccal tablet, pill as required, below is production method:
The production method of medicated powder:
In proportion above-mentioned nine kinds of Chinese herbal medicine are cleaned (disregarding Mel), pulverizing is also crossed 200 mesh sieves, with paper bag or plastic bag packing, refills box, adds the Mel decoction when ill, perhaps mixes with Folium Camelliae sinensis, is distributed into 1-2 with paper bag and restrains a bag, as the teabag Instant Drinks.
The production method of concentrated medicament:
In proportion above-mentioned nine kinds of Chinese herbal medicine are cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leaching medicinal residues discards, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel again, bottling, sterilization obtain product, this product called after " the celestial spirit of larynx " medicinal liquid.
When lacking refluxing unit and distillation equipment, also can boil 2-3 elimination and shake slag with water purification, merge medicinal liquid, reconcentration to water content is the concentrated medicament of 30-50%, adds Mel again, bottling, sterilization obtain product.The production method of capsule and tablet:
Method by above-mentioned production concentrated medicament makes alcohol extract and water extract earlier, further concentrates, and adds Mel and filling material, and tabletting or incapsulate obtains product, this product called after " the celestial spirit of larynx " tablet or " the celestial spirit of larynx " capsule.
The production method of buccal tablet:
In proportion above-mentioned nine kinds of Chinese herbal medicine are cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leaching medicinal residues discards, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel, further concentrate, add Herba Menthae and white sugar again, make buccal tablet.
The production method of pill:
Method by above-mentioned production concentrated medicament makes alcohol extract and water extract earlier, further concentrates, and adds Mel and filling material, makes pill and obtains product, this product called after " the celestial spirit of larynx " pill.
Pharmacological effect: medicine of the present invention can be eliminated the inflammation that the evil poison of each internal organs causes in the human body, more can regulate each internal organs nervous system running balance in the human body, can also health invigorating and improve immunity, have heat-clearing and toxic substances removing, yin nourishing pathogenic fire reducing, depressed liver-energy dispersing and QI regulating, stomach function regulating spleen invigorating, damp eliminating antiinflammatory, sterilization, detumescence, pain relieving, antipruritic, reduce phlegm, effects such as sound producing and blood fat reducing.
The present invention compared with the prior art, substantive distinguishing features that it is outstanding and obvious improvement are beneficial to health, can win victory with unique drug effect of quick-acting specially good effect treating both the principal and the secondary aspects of a disease at the same time, no matter be acute or chronic, can both thoroughly effecting a radical cure of many years ago or recent morbidity, its special advantages is arranged, be subjected to liking and praising of patient deeply.Compare, control throat disease medicine such as tablet more than on the current market, the capsule spray, all kinds such as agent that wet one's whistle, taking stopgap measures can be good, but it is not good enough to effect a permanent cure, just differ widely and moisten celestial spirit, the inflammation that the evil poison of each internal organs causes in the human body is eliminated in the scientific composition treating both the principal and the secondary aspects of a disease at the same time, more can regulate the interior five hollow organs six dirty central nervous system of human body and operate balance, can also health invigorating and raising immunologic function.
In addition, what medicine of the present invention adopted all is common Chinese herbal medicine, without any side effects.
Concentrated medicament of the present invention carries out acute toxicity test by the provincial college of traditional Chinese medicine, and concrete grammar and result are as follows:
Summary: the celestial clever herb liquid The acute toxicity tests of larynx shows that give the Kunming mouse gastric infusion for reagent, maximum tolerated dose (MTD) is the 500g crude drug.Press 60kg/ people and calculate, 2 times/day, 50g/ time, promptly be equivalent to 300 times of the clinical consumption per day of people.
Test sample: the celestial medicine liquid of larynx, adopt the celestial medicine liquid of the well-done larynx of 6 bags to be total to 1050ml and be concentrated into 105ml (promptly 10: 1) in water-bath
The animal experiment condition: Kunming mouse, regular grade, male and female half and half, body weight 18-22g is provided by Colleges Of Traditional Chinese Medicine Of Guangxi, the animal quality certification number: No. the 1104th, the moving word of osmanthus doctor.
Test method and result: get 20 of Kunming mouses, each 10 of male and female, fasting is after 12 hours, give for reagent 0.5ml/10g/ time, gastric infusion is every 4 hours times, totally 4 times, total dosage is 500g crude drug/kilogram, observes signs of toxicity and the death condition of animal after the administration.
The result: after the administration in 7 days mice movable normal, no abnormality seens such as animal appearance, behavior, feed, the activity of observation extremity, breathing and defecation, animal hair is bright and clean, after 2 male and 7 female mice self administration of medication are arranged, go out to advise the soft stool in 8 hours, other index is all normal, do not see dead the generation, male mouse weightening finish 2.95 ± 1.3g after the administration, rate of body weight gain is 15.82%.Female Mus weightening finish 4.40 ± 1.13g, rate of body weight gain is 22.17%.
Conclusion: give mouse stomach administration (ig) with test sample, maximum tolerated dose (MDT) is 500/kg, is limited to the administration capacity of drug level and animal, can't measure LD
50. the celestial clever herb liquid toxicity of larynx that shows censorship is low.
The specific embodiment
Embodiment 1
With dried medicinal material honeysuckle 12 grams, chrysanthemum 8 grams, Radix Isatidis 25 grams, oldenlandia diffusa 8 grams, balloonflower root 5 grams, cicada slough 4 Gram, Flos Ilicis Asprellae 20 gram, dandelion 12 grams, Radix Glycyrrhizae 3 grams were pulverized 200 mesh sieves, earlier with the second of 2-3 times of weight 50-90% Alcohol extracted 1-2 hour in the backflow closed container, filtered out the dregs of a decoction, obtained alcohol extract, pressed dregs of a decoction weighing scale again and added 3-5 The water purification of times weight boiled 1-2 hour with slow fire, leached the dregs of a decoction and discarded, and obtained water extraction liquid, merged alcohol extract and water extraction liquid, Use way of distillation Recycled ethanol, add honey 16 grams again, bottling, sterilization obtain " the celestial spirit of larynx " soup product.
Embodiment 2
With dried medicinal material honeysuckle 15 grams, chrysanthemum 9 grams, Radix Isatidis 20 grams, oldenlandia diffusa 7 grams, balloonflower root 8 grams, cicada slough 5 Gram, Flos Ilicis Asprellae 30 grams, dandelion 15 grams, Radix Glycyrrhizae 4 grams were pulverized 200 mesh sieves, with paper bag or polybag packing, refilled Box adds the honey decoction or takes after mixing it with water when ill.
Embodiment 3
With dried medicinal material honeysuckle 14 grams, chrysanthemum 8 grams, Radix Isatidis 28 grams, oldenlandia diffusa 10 grams, balloonflower root 6 grams, cicada slough 6 grams, Flos Ilicis Asprellae 25 grams, dandelion 15 grams, Radix Glycyrrhizae 5 grams were pulverized 200 mesh sieves, earlier with 2-3 times of weight 50-90%'s Ethanol extracted 1-2 hour in the backflow closed container, filtered out the dregs of a decoction, obtained alcohol extract, pressed dregs of a decoction weighing scale again and added 3-5 The water purification of times weight boiled 1-2 hour with slow fire, leached the dregs of a decoction and discarded, and obtained water extraction liquid, merged alcohol extract and water extraction liquid, Use way of distillation Recycled ethanol, further concentrate, add honey 18 gram and filling materials again, compressing tablet or incapsulate obtains producing Product, this product called after " the celestial spirit of larynx " tablet or " the celestial spirit of larynx " capsule.
Embodiment 4
With dried medicinal material honeysuckle 12 grams, chrysanthemum 9 grams, Radix Isatidis 23 grams, oldenlandia diffusa 9 grams, balloonflower root 6 grams, cicada slough 5 Gram, Flos Ilicis Asprellae 25 gram, dandelion 15 grams, Radix Glycyrrhizae 5 grams were pulverized 200 mesh sieves, earlier with the second of 2-3 times of weight 50-90% Alcohol extracted 1-2 hour in the backflow closed container, filtered out the dregs of a decoction, obtained alcohol extract, pressed dregs of a decoction weighing scale again and added 3-5 The water purification of times weight boiled 1-2 hour with slow fire, leached the dregs of a decoction and discarded, and obtained water extraction liquid, merged alcohol extract and water extraction liquid, Use way of distillation Recycled ethanol, further concentrate, add again honey 18 grams, peppermint 1-2 gram, sucrose 100 restrains, and makes to contain Sheet.
Using method;
Two and one oral liquid, three bottles of oral liquids of every box and 18 lozenges. 200 milliliters every bottle, lozenge 1g/ grain, per day for adults Take one bottle, 6 of lozenges, the infant takes 1/4 bottle every day, 3 of lozenges, take 1/2 bottle, lozenge 2 every days one full year of life one full year of life to 5 3, take 3/4 bottle 6 every days one full year of life one full year of life to 10,6 of lozenges, and take one bottle above every day of 11 one full year of life, 6 of lozenges, only To take oral liquid every day once, lozenge 3---6, take before sleeping after the supper, serve on three days, can thoroughly fully recover.
The medicinal powder using method; Every box has three bottles of medicinal powder, every bottle 40 gram, and per day for adults takes one bottle, and the infant takes 1/3 bottle every day; Take 1/2 bottle 2 every days one full year of life one full year of life to 5, and take 1 bottle 6 every days one full year of life one full year of life to 10, serve on once a day three days, can be thorough End recovery from illness.
The treatment example:
1, thank to * *, the man, 30 years old, the workman, the Zhanjiang, Guangdong Province people requires inventor's diagnosis and treatment, symptom July nineteen ninety-five Be hoarseness, scorching hot in the larynx, the larynx dry cough of itching, body temperature 39 degree are acute laryngitis after diagnosing, give medicine " larynx of the present invention Celestial spirit " liquid medicine applying, took medicine after the supper 200 milliliters the same day, and the hoarseness symptom is clearly better, and pronunciation is burnt in the larynx smoothly Heat is red and swollen to disappear, and body temperature is normal. In order to consolidate curative effect, serve on two days, every day twice, thoroughly recovery from illness.
2, poplar * *, the woman, 33 years old, the peasant, Wuchuan City, Guangdong Province Huang Po people from town, according to telling: the stupid disease of throat, often repeatedly outbreak, Need the refrigerant lozenge of informal dress, with antiphlogistic, spray etc., headache, thirsty, pectoralgia, appetite appear in and often cat fever The symptom such as depressed was found the larynx dry cough of itching the same day, hoarseness, and breathing is breathed hard, and the throat redness is swallowed pain, and tonsillotome is swollen Greatly, treat to clinic and to have no improvement, the place requires diagnosis and treatment July nineteen ninety-five to the inventor, is diagnosed as chronic laryngopharyngitis, Give medicine of the present invention " larynx celestial spirit " liquid medicine applying, took medicine the same day 200 milliliters have a headache, thirsty, pectoralgia, larynx are itched dry cough etc. Symptom is clearly better, and the second day appetite takes a turn for the better, and takes medicine twice again, and tonsillotome dwindles, and takes medicine three days, and it is normal that tonsillotome recovers, Red and swollen all disappearances in the larynx, thoroughly recovery from illness is followed up a case by regular visits to and had no recurrence in 5 years, and is healthy, and body weight increases by 15 kilograms.
3, Wu * *, the woman, 7 years old,, Wuchuan City, Guangdong Province Huang Po people from town, cat fever two days, body temperature 39 degree, throat redness Pain, is taken " the celestial spirit of larynx " tablet in diagnosis and treatment in July calendar year 2001, and every day twice, each two, the cat fever symptom disappears Lose, body temperature is normal, and throat congestion and swelling pain symptom also all disappears, and has no adverse reaction.
Claims (6)
1, a kind of health medicine for the treatment of oral cavity and laryngopharyngeal diseases is characterized in that its material composition and weight content are as follows:
Flos Lonicerae 10--15 (weight portion)
Flos Chrysanthemi 8--10 (weight portion)
Radix Isatidis 15--30 (weight portion)
Herba Hedyotidis Diffusae 5--10 (weight portion)
Radix Platycodonis 5--10 (weight portion)
Periostracum Cicadae 3--6 (weight portion)
Flos Ilicis Asprellae 15--30 (weight portion)
Herba Taraxaci 10--15 (weight portion)
Mel 15--20 (weight portion)
Radix Glycyrrhizae 3--6 (weight portion)
2, the production method of the health medicine of a kind of treatment as claimed in claim 1 oral cavity and laryngopharyngeal diseases, it is characterized in that in proportion above-mentioned nine kinds of Chinese herbal medicine being cleaned (disregarding Mel), pulverizing is also crossed 200 mesh sieves, makes medicated powder, perhaps mix, make tea beverage with Folium Camelliae sinensis.
3, the production method of the health medicine of a kind of treatment as claimed in claim 1 oral cavity and laryngopharyngeal diseases, it is characterized in that in proportion above-mentioned nine kinds of Chinese herbal medicine being cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel again, bottling, sterilization obtains medicinal liquid.
4, the production method of the health medicine of a kind of treatment as claimed in claim 1 oral cavity and laryngopharyngeal diseases, it is characterized in that in proportion above-mentioned nine kinds of Chinese herbal medicine being cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filtered out medicinal residues, obtained alcohol extract, the water purification that adds 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add Mel and filling material again, tabletting or incapsulate obtains product.
5, the production method of the health medicine of a kind of treatment as claimed in claim 1 oral cavity and laryngopharyngeal diseases, it is characterized in that in proportion above-mentioned nine kinds of Chinese herbal medicine being cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add again Mel and and white sugar, make buccal tablet.
6, the production method of the health medicine of a kind of treatment as claimed in claim 1 oral cavity and laryngopharyngeal diseases, it is characterized in that in proportion above-mentioned nine kinds of Chinese herbal medicine being cleaned (disregarding Mel), pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add Mel and filling material again, make pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011283467A CN1150927C (en) | 2001-08-12 | 2001-08-12 | Stomatopathy and throat disease treating health care medicine and its production process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011283467A CN1150927C (en) | 2001-08-12 | 2001-08-12 | Stomatopathy and throat disease treating health care medicine and its production process |
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| CN1335174A true CN1335174A (en) | 2002-02-13 |
| CN1150927C CN1150927C (en) | 2004-05-26 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020009B (en) * | 2007-03-05 | 2010-05-19 | 广东南台药业有限公司 | Medicated teafor clearing away heat of pharynx and larynx |
| CN101912112A (en) * | 2010-07-23 | 2010-12-15 | 江苏老蚕坊蚕桑生物科技开发有限公司 | Method for manufacturing compound mulberry leaf throat moistening and cleaning tablet |
| CN101204422B (en) * | 2007-12-12 | 2011-04-13 | 李亚萍 | Chinese traditional medicine preparation for acute tonsillitis |
| CN102068480A (en) * | 2009-11-24 | 2011-05-25 | 西南大学 | Edible and medicinal compound preparation with effects of heatstroke alleviation and detoxification |
| CN102641416A (en) * | 2012-04-19 | 2012-08-22 | 王莲芬 | Chinese patent medicine for treating toothache disease |
| CN104958323A (en) * | 2015-07-23 | 2015-10-07 | 耿佃敖 | Ointment for treating sphagitis and preparation method of ointment |
| CN105267471A (en) * | 2014-07-19 | 2016-01-27 | 葛以东 | Formula for treatment of acute or chronic tonsillitis |
| CN107854592A (en) * | 2017-10-11 | 2018-03-30 | 烟台市口腔医院 | A kind of preparation method for the film for treating oral ulcer that can quickly eliminate pain |
-
2001
- 2001-08-12 CN CNB011283467A patent/CN1150927C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020009B (en) * | 2007-03-05 | 2010-05-19 | 广东南台药业有限公司 | Medicated teafor clearing away heat of pharynx and larynx |
| CN101204422B (en) * | 2007-12-12 | 2011-04-13 | 李亚萍 | Chinese traditional medicine preparation for acute tonsillitis |
| CN102068480A (en) * | 2009-11-24 | 2011-05-25 | 西南大学 | Edible and medicinal compound preparation with effects of heatstroke alleviation and detoxification |
| CN101912112A (en) * | 2010-07-23 | 2010-12-15 | 江苏老蚕坊蚕桑生物科技开发有限公司 | Method for manufacturing compound mulberry leaf throat moistening and cleaning tablet |
| CN102641416A (en) * | 2012-04-19 | 2012-08-22 | 王莲芬 | Chinese patent medicine for treating toothache disease |
| CN105267471A (en) * | 2014-07-19 | 2016-01-27 | 葛以东 | Formula for treatment of acute or chronic tonsillitis |
| CN104958323A (en) * | 2015-07-23 | 2015-10-07 | 耿佃敖 | Ointment for treating sphagitis and preparation method of ointment |
| CN107854592A (en) * | 2017-10-11 | 2018-03-30 | 烟台市口腔医院 | A kind of preparation method for the film for treating oral ulcer that can quickly eliminate pain |
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| CN1150927C (en) | 2004-05-26 |
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