CN100429225C - 原肌生长抑制素肽及其使用方法 - Google Patents

原肌生长抑制素肽及其使用方法 Download PDF

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Publication number
CN100429225C
CN100429225C CNB018149073A CN01814907A CN100429225C CN 100429225 C CN100429225 C CN 100429225C CN B018149073 A CNB018149073 A CN B018149073A CN 01814907 A CN01814907 A CN 01814907A CN 100429225 C CN100429225 C CN 100429225C
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China
Prior art keywords
myostatin
gdf
peptide
receptor
amino acid
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Expired - Fee Related
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CNB018149073A
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English (en)
Chinese (zh)
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CN1449409A (zh
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李瑟瑾
A·C·麦克弗伦
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Johns Hopkins University
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Johns Hopkins University
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Priority claimed from US09/628,112 external-priority patent/US7566768B1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNB018149073A 2000-07-27 2001-07-26 原肌生长抑制素肽及其使用方法 Expired - Fee Related CN100429225C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/628,112 US7566768B1 (en) 1995-10-26 2000-07-27 Promyostatin peptides and methods of using same
US09/628,112 2000-07-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN200710199696.5A Division CN101261277B (zh) 2000-07-27 2001-07-26 原肌生长抑制素肽及其使用方法

Publications (2)

Publication Number Publication Date
CN1449409A CN1449409A (zh) 2003-10-15
CN100429225C true CN100429225C (zh) 2008-10-29

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CNB018149073A Expired - Fee Related CN100429225C (zh) 2000-07-27 2001-07-26 原肌生长抑制素肽及其使用方法
CN200710199696.5A Expired - Fee Related CN101261277B (zh) 2000-07-27 2001-07-26 原肌生长抑制素肽及其使用方法

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CN200710199696.5A Expired - Fee Related CN101261277B (zh) 2000-07-27 2001-07-26 原肌生长抑制素肽及其使用方法

Country Status (14)

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US (3) US7393682B1 (https=)
EP (2) EP2360259A3 (https=)
JP (1) JP5149478B2 (https=)
CN (2) CN100429225C (https=)
AR (1) AR030307A1 (https=)
AU (2) AU8079901A (https=)
BR (1) BRPI0112785B1 (https=)
CA (1) CA2416260A1 (https=)
IL (2) IL153970A0 (https=)
MX (1) MXPA03000786A (https=)
NZ (2) NZ523672A (https=)
PL (1) PL210158B1 (https=)
WO (1) WO2002009641A2 (https=)
ZA (1) ZA200300483B (https=)

Cited By (1)

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CN109071645A (zh) * 2016-01-08 2018-12-21 供石公司 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法

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CN111793123B (zh) * 2019-04-08 2022-03-08 中国农业大学 一种肌肉生长抑制素mstn的突变体及其应用
CN110192624A (zh) * 2019-07-05 2019-09-03 福建冠丰生物科技有限公司 一种海参牡蛎营养物口服含片及其制备方法
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NZ523672A (en) 2006-02-24
NZ542696A (en) 2008-02-29
AU8079901A (en) 2002-02-13
EP1303534A2 (en) 2003-04-23
IL153970A (en) 2012-08-30
BR0112785A (pt) 2003-07-01
EP1303534A4 (en) 2004-09-01
WO2002009641A9 (en) 2003-03-20
MXPA03000786A (es) 2004-05-21
BRPI0112785B1 (pt) 2016-07-12
US7393682B1 (en) 2008-07-01
EP2360259A3 (en) 2011-11-16
CA2416260A1 (en) 2002-02-07
AR030307A1 (es) 2003-08-20
WO2002009641A2 (en) 2002-02-07
PL365780A1 (en) 2005-01-10
EP2360259A2 (en) 2011-08-24
JP2004504826A (ja) 2004-02-19
CN1449409A (zh) 2003-10-15
CN101261277A (zh) 2008-09-10
CN101261277B (zh) 2014-03-12
WO2002009641A3 (en) 2002-05-10
JP5149478B2 (ja) 2013-02-20
PL210158B1 (pl) 2011-12-30
ZA200300483B (en) 2004-02-19
US20110239317A1 (en) 2011-09-29
AU2001280799B2 (en) 2006-06-08
US8323964B2 (en) 2012-12-04
IL153970A0 (en) 2003-07-31
US20090017522A1 (en) 2009-01-15

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