CN100355448C - 一种防治酒精性肠道损伤和肝损伤的中药复方制剂 - Google Patents
一种防治酒精性肠道损伤和肝损伤的中药复方制剂 Download PDFInfo
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Abstract
Description
组别 | n | 肝TG含量(mg/g) | 脂肪变性积分 |
正常组无酒精饲料对照组酒精饲料模型组酒精饲料+中药复方组 | 5998 | 13.31±4.2439.32±17.3498.82±8.74**71.77±19.33△△ | 0±00.73±0.653.58±0.90**2.50±0.90△△ |
组别 | n | ALT活性(U/L) | AST活性(U/L) | 肝r-GT活性(U/gprot) |
正常组无酒精饲料对照组酒精饲料模型组酒精饲料+中药复方组 | 5998 | 28±11.917±6.675±44.8**35±24.6△ | 66±12.172±13.8108±27.0**90±30.0 | 106±81100±50493±132**243±107△△ |
组别 | n | MDA含量(nmol/mgprot) | Fe2+含量(umol/L) | NOS活性(U/mgprot) |
无酒精饲料对照组酒精饲料模型组酒精饲料+中药复方组 | 998 | 5.92±0.979.28±2.41**6.68±1.10△ | 62.8±14.196.7±25.6**70.5±19.7△ | 7.7±1.524.8±5.8**15.8±4.8△ |
组别 | n | SOD活性(U/mgprot) | GSH含量(mg/gprot) | GSHPx活性(U) | 抗活性氧单位(U/mgprot) |
正常组无酒精饲料对照组酒精饲料模型组酒精饲料+中药复方组 | 5998 | 118±15133±1199±12**106±12 | 45.9±3.949.1±4.651.3±3.144.9±5.6△ | 9.91±1.6011.43±1.769.74±1.69*9.42±1.93 | 235.8±53.6236.5±81.878.1±49.0**134.6±85.9△ |
组别 | n | 内毒素含量(EU/ml) |
正常组酒精液体饲料组酒精液体饲料+中药复方组 | 598 | 0.04±0.024b0.34±0.0190.13±0.075bf |
组别 | n | 血清ALT活性(U/L) |
正常组+LPS无酒精液体饲料组+LPS酒精液体饲料+LPS酒精液体饲料组+LPS+中药 | 6111212 | 39±4b24±7b96±2275±18a |
组别 | n | 肝组织TG含量(mg.g1湿肝) |
正常组+LPS无酒精液体饲料组+LPS酒精液体饲料+LPS酒精液体饲料组+LPS+中药 | 6111212 | 38.93±16.51b75.37±23.3b365.59±50.42245.59±63.85b |
组别 | n | 脂肪变性计分 |
正常组+LPS无酒精液体饲料组+LPS酒精液体饲料+LPS酒精液体饲料组+LPS+中药 | 6111212 | 0±0b0.73±0.65b3.58±0.92.5±0.9b |
组别 | n | 门静脉内毒素含量(EU/ml) |
正常组+LPS无酒精液体饲料组+LPS酒精液体饲料+LPS酒精液体饲料组+LPS+中药 | 6111212 | 1.893±0.086b2.447±0.548b3.928±0.323.336±0.092b |
组别 | n | 血浆TNF-α含量(pg/ml) |
正常组+LPS无酒精液体饲料组+LPS酒精液体饲料+LPS酒精液体饲料组+LPS+中药 | 6111212 | 14.97±1.52b15.91±1.19b29.55±3.3726±2.77a |
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JP5764288B2 (ja) * | 2009-09-24 | 2015-08-19 | ハウス食品グループ本社株式会社 | ウコン抽出物とガジュツ抽出物とを含有する組成物 |
CN102961522B (zh) * | 2011-09-01 | 2014-07-30 | 上海中医药大学附属曙光医院 | 一种防治酒精性肠病的中药复方制剂 |
CN105999212A (zh) * | 2016-05-13 | 2016-10-12 | 无限极(中国)有限公司 | 一种具有解酒作用的组合物及其制备方法与用途 |
CN110787272A (zh) * | 2019-11-13 | 2020-02-14 | 上海现代中医药股份有限公司 | 一种中药复方在制备治疗非酒精性脂肪性肝炎的药物中的应用 |
CN112595698A (zh) * | 2020-11-18 | 2021-04-02 | 上海中医药大学 | 油红o的应用及定量检测组织或细胞内脂质的方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1231202A (zh) * | 1998-01-17 | 1999-10-13 | 吴书西 | 治疗结肠炎的中药制剂 |
CN1331996A (zh) * | 2001-05-20 | 2002-01-23 | 许喜训 | 乙肝转阴丸 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1231202A (zh) * | 1998-01-17 | 1999-10-13 | 吴书西 | 治疗结肠炎的中药制剂 |
CN1331996A (zh) * | 2001-05-20 | 2002-01-23 | 许喜训 | 乙肝转阴丸 |
Non-Patent Citations (1)
Title |
---|
健脾活血方治疗脂肪肝的临床研究 何东仪等.中西医结合肝病杂志,第10卷第3期 2000 * |
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