CN100345568C - Chinese-medicinal preparation for treating prostatic disease - Google Patents

Chinese-medicinal preparation for treating prostatic disease Download PDF

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CN100345568C
CN100345568C CNB2006100909077A CN200610090907A CN100345568C CN 100345568 C CN100345568 C CN 100345568C CN B2006100909077 A CNB2006100909077 A CN B2006100909077A CN 200610090907 A CN200610090907 A CN 200610090907A CN 100345568 C CN100345568 C CN 100345568C
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radix
chinese medicine
paeoniae rubra
fine powder
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CN1895463A (en
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王连喜
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Shi Changshan
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Abstract

A Chinese medicine for treating prostatism is prepared from 18 Chinese-medicinal materials including dandelion herb, epimedium, dodder seed, astragalus root, etc. Its preparing process is also disclosed.

Description

A kind of treatment prostatosis Chinese medicine preparation and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation for the treatment of prostatosis and preparation method thereof.
Background technology
Chronic prostatitis mainly shows as dysuria, drop and lacking, or drench the puckery pain of drop, diseases such as cramp and pain in the lower abdomen.The category that belongs to the traditional Chinese medical science " difficulty in urination " " stranguria ".In close relations with kidney, bladder.State's internal therapy prostatitis mainly adopts western medicine therapy, many with antibiotic such as sulfonamides, quinolione classes with medicine for urological system, owing to the particularity of prostate anatomical physiology position, outward by lipid envelope, the antibiotic medicine ion is difficult to penetrate, curative effect is relatively poor, and direct drug injection thing iontophoresis or per urethra are intended the filling method, though curative effect is rapid-action, but operation inconvenience, cause bleeding easily, cause double infection and form scleroma, seondary effect is many.
External a large amount of utilization a-receptor blocking agents reduce bladder outlet resistance and urethral orifice closing presure, as hytrin, and prazosin etc., also useful 5a-reductase suppresses the generation of pair hydrogen testosterones in the human body, as proscar etc.The said medicine curative effect still can, but price is all expensive and bigger to the blood pressure influence, still can not promote, domestic and international multiple western medicine therapy is analyzed on the whole, curative effect is not good enough, and side effect is many, and is especially obvious to the patient who suffers from some other complications.
Summary of the invention
Purpose of the present invention overcomes the deficiencies in the prior art exactly, provides a kind of evident in efficacy, and the Chinese medicine preparation of the chronic prostatitis that treatment deficiency of the kidney etc. causes makes it to be fit to clinical practice.
An object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of prostatosis.
Another object of the present invention provides the preparation method of described treatment prostatosis Chinese medicine preparation.
The objective of the invention is to be achieved through the following technical solutions:
A kind of Chinese medicine preparation for the treatment of prostatosis is by comprising that following parts by weight of traditional Chinese medicines feedstock production forms;
Herba Taraxaci 110-130 Herba Epimedii 70-85 Herba Hedyotidis Diffusae 110-128
Herba Patriniae 65-90 Herba Houttuyniae 65-90 Herba Pyrolae 75-90
Herba Violae 68-85 Radix Rehmanniae Preparata 40-60 Cortex Phellodendri 32-48
Semen Cuscutae 35-46 Herba Cistanches 41-56 Fructus Rubi 69-88
Flos Chrysanthemi Indici 40-55 Radix Astragali 35-53 Rhizoma Atractylodis Macrocephalae 30-48
Radix Angelicae Sinensis 33-50 Radix Paeoniae Rubra 35-48 Flos Carthami 10-25
Radix Glycyrrhizae 18-28
Preferably, a kind of Chinese medicine preparation for the treatment of prostatosis, by comprising that following parts by weight of traditional Chinese medicines feedstock production forms:
Herba Taraxaci 115-125 Herba Epimedii 78-85 Herba Hedyotidis Diffusae 113-125
Herba Patriniae 70-85 Herba Houttuyniae 75-85 Herba Pyrolae 80-85
Herba Violae 75-80 Radix Rehmanniae Preparata 45-55 Cortex Phellodendri 36-45
Semen Cuscutae 37-42 Herba Cistanches 45-55 Fructus Rubi 80-88
Flos Chrysanthemi Indici 45-55 Radix Astragali 40-50 Rhizoma Atractylodis Macrocephalae 40-45
Radix Angelicae Sinensis 40-50 Radix Paeoniae Rubra 35-40 Flos Carthami 15-20
Radix Glycyrrhizae 18-25
A kind of preparation method for the treatment of the Chinese medicine preparation of prostatosis of the present invention, method one: it may further comprise the steps;
1, take by weighing each raw material by formula ratio, it is standby that half amount of getting the Radix Astragali and Radix Paeoniae Rubra is ground into fine powder R;
2, the five tastes such as Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and Flos Chrysanthemi Indici extract volatile oil A with the way of distillation, and the aqueous solution B and the medicinal residues C that collect after distilling are standby; 12 flavors such as second half amount of medicinal residues C and the Radix Astragali, Radix Paeoniae Rubra and all the other Herba Taraxacis are decocted with water three times, and collecting decoction adds above-mentioned aqueous solution B, filter, filtrate concentrates, room temperature to be chilled to, add ethanol, leave standstill, get supernatant concentration and become thick paste, the fine powder R that adds step 1 gained, mixing, drying is ground into fine powder, spray into volatile oil A stirring and evenly mixing, drying, pulverizing, make Chinese medicine preparation of the present invention.
A kind of preparation method for the treatment of the Chinese medicine preparation of prostatosis of the present invention, method two: it may further comprise the steps;
1, take by weighing each raw material by formula ratio, it is standby that half amount of getting the Radix Astragali and Radix Paeoniae Rubra is ground into fine powder R;
2, the five tastes such as Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and Flos Chrysanthemi Indici extract volatile oil A with the way of distillation, and the aqueous solution B and the medicinal residues C that collect after distilling are standby; 12 flavors such as second half amount of medicinal residues C and the Radix Astragali, Radix Paeoniae Rubra and all the other Herba Taraxacis are decocted with water three times, collecting decoction adds above-mentioned aqueous solution B, filters, filtrate is by after the macroporous resin adsorption, use the 20%-80% ethanol elution, collect eluent, reclaim ethanol, be condensed into thick paste, the fine powder R and the volatile oil A that add step 1 gained, are ground into fine powder at mixing, drying, make Chinese medicine preparation of the present invention.
A kind of Chinese medicine preparation for the treatment of prostatosis of the present invention, it is made into various dosage forms, comprises capsule, tablet, granule, soft capsule, drop pill etc.
The Chinese medicine preparation of treatment prostatosis of the present invention, dosage form: tablet, usage: oral, every day three times, each 2-4 sheet, 6 days is a course of treatment.
A kind of Chinese medicine preparation for the treatment of prostatosis of the present invention, Herba Taraxaci in the side, bitter, sweet, cold, heat-clearing and toxic substances removing; Herba Epimedii, hot, sweet, warm, warming the kidney to activate YANG, expelling wind and removing dampness is monarch drug altogether.Herba Hedyotidis Diffusae, Herba Patriniae, Herba Houttuyniae, Herba Violae, Flos Chrysanthemi Indici, Cortex Phellodendri help Herba Taraxaci with the evil poison of removing summer-heat damp-heat in lower-JIAO altogether; Radix Rehmanniae Preparata, Herba Pyrolae, Semen Cuscutae, Herba Cistanches, Fructus Rubi help Herba Epimedii with warming and recuperating the kidney-YANG altogether, are ministerial drug altogether.The Radix Astragali, Rhizoma Atractylodis Macrocephalae invigorating the spleen and replenishing QI; Radix Angelicae Sinensis, Radix Paeoniae Rubra, Flos Carthami promoting blood circulation to remove obstruction in the collateral are adjuvant drug altogether; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is a messenger drug.
A kind of Chinese medicine preparation for the treatment of prostatosis of the present invention adopts multiple rare Chinese medicine in the side, have the kidney invigorating and essence nourishing, blood circulation promoting and blood stasis dispelling, and the function of eliminating damp, detoxifying is used for the treatment of deficiency of the kidney, stagnation of blood stasis; The diseases such as chronic prostatitis that damp-heat accumulation causes, and without any side effects, not only solve prostate, a glandular envelope barrier difficult problem, and breakthrough used " kidney-gland double-effect concurrent treat " therapy to make the patient promptly cure prostate, recover sexual function again, and stopped prostatic recurrence.
The specific embodiment
Following examples are in order further to describe the present invention for example, rather than limit the present invention by any way.
Embodiment 1
Herba Taraxaci 125kg Herba Epimedii 78kg Herba Hedyotidis Diffusae 115kg
Herba Patriniae 70kg Herba Houttuyniae 80kg Herba Pyrolae 75kg
Herba Violae 80kg Radix Rehmanniae Preparata 50kg Cortex Phellodendri 45kg
Semen Cuscutae 42kg Herba Cistanches 48kg Fructus Rubi 80kg
Flos Chrysanthemi Indici 45kg Radix Astragali 40kg Rhizoma Atractylodis Macrocephalae 40kg
Radix Angelicae Sinensis 40kg Radix Paeoniae Rubra 40kg Flos Carthami 18kg
Radix Glycyrrhizae 23kg
Its preparation method is as follows:
1, take by weighing each raw material by formula ratio, getting each 20kg of the Radix Astragali and Radix Paeoniae Rubra, to be ground into fine powder R standby;
2, the five tastes such as Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and Flos Chrysanthemi Indici extract volatile oil A with the way of distillation, and the aqueous solution B and the medicinal residues C that collect after distilling are standby; With the medicinal residues C and the 20kg Radix Astragali, 12 flavors such as 20 Radix Paeoniae Rubra and all the other Herba Taraxacis decoct with water three times, 1 hour for the first time, reach each 0.5 hour for the third time for the second time, collecting decoction adds above-mentioned aqueous solution B, filters, filtrate is concentrated into relative density and is about 1.08 (90-95 ℃), room temperature to be chilled to adds ethanol and makes and contain alcohol amount and reach 75%, leaves standstill, get the thick paste that supernatant concentration to relative density is 1.20-1.24 (75 ℃), the fine powder R that adds step 1 gained, mixing, drying, be ground into fine powder, spray into volatile oil A stirring and evenly mixing, drying is made Film coated tablets according to Chinese Pharmacopoeia version two-shift system in 2005 agent standard.
Embodiment 2
Herba Taraxaci 110kg Herba Epimedii 83kg Herba Hedyotidis Diffusae 120kg
Herba Patriniae 80kg Herba Houttuyniae 75kg Herba Pyrolae 85kg
Herba Violae 70kg Radix Rehmanniae Preparata 43kg Cortex Phellodendri 35kg
Semen Cuscutae 40kg Herba Cistanches 53kg Fructus Rubi 80kg
Flos Chrysanthemi Indici 50kg Radix Astragali 50kg Rhizoma Atractylodis Macrocephalae 40kg
Radix Angelicae Sinensis 35kg Radix Paeoniae Rubra 36kg Flos Carthami 15kg
Radix Glycyrrhizae 26kg
Its preparation method is as follows:
1, take by weighing each raw material by formula ratio, getting Radix Astragali 25kg and Radix Paeoniae Rubra 18kg, to be ground into fine powder R standby;
2, the five tastes such as Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and Flos Chrysanthemi Indici extract volatile oil A with the way of distillation, and the aqueous solution B and the medicinal residues C that collect after distilling are standby; Medicinal residues C and 12 flavors such as the 25kg Radix Astragali, 18kg Radix Paeoniae Rubra and all the other Herba Taraxacis are decocted with water three times, 1 hour for the first time, reach each 0.5 hour for the third time for the second time, collecting decoction adds above-mentioned aqueous solution B, filters, filtrate is used 70% ethanol elution by after the macroporous resin adsorption, collects eluent, reclaim ethanol, be condensed into thick paste, add the fine powder R and the volatile oil A of step 1 gained, mixing, drying, be ground into fine powder, according to Chinese Pharmacopoeia version two-shift system in 2005 agent standard, make soft capsule.
Below be the Chinese medicine preparation of the invention process 1 treatment prostatosis over 2 years to 96 patients' clinical experiment, received quite satisfied effect, this clinical observation of curative effect for details see attached table 1.
Subordinate list 1
State of an illness classification clinical setting Chronic prostatitis Add up to
Case load 98 98
Drug treatment 1-3 4-5 6-8 1-8
Cure 13 35 31 79
Effectively 16 16
Invalid 3 3
Above experimental data shows that this Chinese medicine preparation has the prostatitic effect of obvious treatment, for extensive patients has been removed misery.

Claims (3)

1. a Chinese medicine preparation for the treatment of prostatosis is formed by following parts by weight of traditional Chinese medicines feedstock production;
Herba Taraxaci 110-130 Herba Epimedii 70-85 Serpentis SHECAO 110-128
Herba Patriniae 65-90 Herba Houttuyniae 65-90 Herba Pyrolae 75-90
Herba Violae 68-85 Radix Rehmanniae Preparata 40-60 Cortex Phellodendri 32-48
Semen Cuscutae 35-46 Herba Cistanches 41-56 Fructus Rubi 69-88
Flos Chrysanthemi Indici 40-55 Radix Astragali 35-53 Rhizoma Atractylodis Macrocephalae 30-48
Radix Angelicae Sinensis 33-50 Radix Paeoniae Rubra 35-48 Flos Carthami 10-25
Radix Glycyrrhizae 18-28;
Said preparation is capsule, tablet, granule, drop pill, oral liquid, and its preparation method may further comprise the steps;
1), take by weighing each raw material by formula ratio, to be ground into fine powder R standby for half amount of getting the Radix Astragali and Radix Paeoniae Rubra;
2), Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and the Flos Chrysanthemi Indici five tastes extract volatile oil A with the way of distillation, the aqueous solution B and the medicinal residues C that collect after the distillation are standby; 12 flavor Chinese medicines such as second half amount of medicinal residues C and the Radix Astragali, Radix Paeoniae Rubra and all the other Herba Taraxacis are decocted with water three times, and collecting decoction adds above-mentioned aqueous solution B again, filter, filtrate concentrates, room temperature to be chilled to, add ethanol, make to contain alcohol amount and reach 75%, leave standstill, get supernatant concentration and become thick paste, the fine powder R that adds step 1 gained, mixing, drying, be ground into fine powder, spray into volatile oil A stirring and evenly mixing, drying, pulverizing, make described Chinese medicine preparation.
2. a Chinese medicine preparation for the treatment of prostatosis is formed by following parts by weight of traditional Chinese medicines feedstock production;
Herba Taraxaci 110-130 Herba Epimedii 70-85 Herba Hedyotidis Diffusae 110-128
Herba Patriniae 65-90 Herba Houttuyniae 65-90 Herba Pyrolae 75-90
Herba Violae 68-85 Radix Rehmanniae Preparata 40-60 Cortex Phellodendri 32-48
Semen Cuscutae 35-46 Herba Cistanches 41-56 Fructus Rubi 69-88
Flos Chrysanthemi Indici 40-55 Radix Astragali 35-53 Rhizoma Atractylodis Macrocephalae 30-48
Radix Angelicae Sinensis 33-50 Radix Paeoniae Rubra 35-48 Flos Carthami 10-25
Radix Glycyrrhizae 18-28;
Said preparation is capsule, tablet, granule, soft capsule, drop pill, oral liquid, and its preparation method may further comprise the steps;
1), take by weighing each raw material by formula ratio, to be ground into fine powder R standby for half amount of getting the Radix Astragali and Radix Paeoniae Rubra;
2), Herba Patriniae, Herba Houttuyniae, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis and the Flos Chrysanthemi Indici five tastes extract volatile oil A with the way of distillation, the aqueous solution B and the medicinal residues C that collect after the distillation are standby; 12 flavor Chinese medicines such as second half amount of medicinal residues C and the Radix Astragali, Radix Paeoniae Rubra and all the other Herba Taraxacis are decocted with water three times, collecting decoction adds above-mentioned aqueous solution B again, filters, filtrate is by after the macroporous resin adsorption, use the 20%-80% ethanol elution, collect eluent, reclaim ethanol, be condensed into thick paste, the fine powder R and the volatile oil A that add step 1 gained again, are ground into fine powder at mixing, drying, make described Chinese medicine preparation.
3. a kind of Chinese medicine preparation for the treatment of prostatosis according to claim 1 and 2 is characterized in that the parts by weight of each raw material of Chinese medicine are:
Herba Taraxaci 115-125 Herba Epimedii 78-85 Herba Hedyotidis Diffusae 113-125
Herba Patriniae 70-85 Herba Houttuyniae 75-85 Herba Pyrolae 80-85
Herba Violae 75-80 Radix Rehmanniae Preparata 45-55 Cortex Phellodendri 36-45
Semen Cuscutae 37-42 Herba Cistanches 45-55 Fructus Rubi 80-88
Flos Chrysanthemi Indici 45-55 Radix Astragali 40-50 Rhizoma Atractylodis Macrocephalae 40-45
Radix Angelicae Sinensis 40-50 Radix Paeoniae Rubra 35-40 Flos Carthami 15-20
Radix Glycyrrhizae 18-25.
CNB2006100909077A 2006-06-30 2006-06-30 Chinese-medicinal preparation for treating prostatic disease Active CN100345568C (en)

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Publication number Priority date Publication date Assignee Title
CN101912477B (en) * 2010-08-02 2011-11-09 吴宝国 Health-care tea
CN102058715B (en) * 2010-12-20 2012-06-06 郭瑶 Chinese medicine preparation for treating chronic prostatitis and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1631433A (en) * 2004-11-15 2005-06-29 长春今来药业(集团)有限公司 Capsule for treating prostate disease and its preparing process
CN1895462A (en) * 2006-06-29 2007-01-17 王建辉 Nankang soft capsule for treating prostatitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1631433A (en) * 2004-11-15 2005-06-29 长春今来药业(集团)有限公司 Capsule for treating prostate disease and its preparing process
CN1895462A (en) * 2006-06-29 2007-01-17 王建辉 Nankang soft capsule for treating prostatitis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
2002年中华中医药学会男科学学术大会纪要 曾庆琪等,中华男科学,第8卷第5期 2002 *
中药成方制剂 137 1998 *
中药成方制剂 175 1998 *

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