CN100333780C - Chinese medicine for antisenility and its preparation method - Google Patents
Chinese medicine for antisenility and its preparation method Download PDFInfo
- Publication number
- CN100333780C CN100333780C CNB2005100198475A CN200510019847A CN100333780C CN 100333780 C CN100333780 C CN 100333780C CN B2005100198475 A CNB2005100198475 A CN B2005100198475A CN 200510019847 A CN200510019847 A CN 200510019847A CN 100333780 C CN100333780 C CN 100333780C
- Authority
- CN
- China
- Prior art keywords
- parts
- rhizoma
- radix
- present
- portions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a Chinese medicine for delaying senility, which is mainly prepared from the following raw material medicines according to the portion by weight: 15 to 100 portions of astragalus root, 3 to 50 portions of Chuan-xiong rhizome, 3 to 30 portions of peach kernel, 3 to 30 portions of safflower, 9 to 60 portions of solomonseal rhizome, 3 to 30 portions of zedoary and 5 to 50 portions of wine made rhubarb. The present invention follows the rules of human senility and grasps macroscopic and microscopic factors which result in senility. The present invention improves human circulation and microcirculation, promotes blood circulation to remove blood stasis, reduces intracellular free radicals and the concentration of harmful substances and reduces the absorption of intestinal tracts to the harmful substances. The present invention blocks or delays the pathologic processes of senility from three aspects, which is the difference between the present invention and other prescriptions for delaying senility. The present invention can be used for the auxiliary treatment of senile commonly encountered diseases and frequently encountered diseases.
Description
Affiliated technical field
The present invention relates to technical field of Chinese medicines.Relate in particular to delay aging drug medicine and preparation method thereof.
Background technology
Aging slow property, carrying out property, degenerative function that to be body occur with age growth reduce, and the general performance of general, multisystem, gradual deterioration process occurs.The antiaging agent of using clinically has two mistaken ideas at present: the one, use so-called tonic; The 2nd, be confined to antidotal medication in a certain respect.Medication like this, though can produce the effect of some locality, because aging is physiology that a causes general, multifactor and/or pathological process, administration time is long slightly, curative effect has promptly lost.
Summary of the invention
Therefore, still there is demand in people to the better delay aging drug preparation of curative effect.Up to now, also there is not to find to have the report of any relevant pharmaceutical composition of the present invention.The inventor is using for reference on the basis of ancient prescription, through research repeatedly, and the checking repeatedly by clinical trial, find the delay aging drug endo-medicine of better curative effect finally, thereby finished the present invention.
The objective of the invention is provides a kind of more efficiently delay aging drug medicine and preparation method thereof at the problems referred to above.
The medicament selection Radix Astragali of the present invention, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Rhizoma Polygonati, Rhizoma Curcumae and Radix et Rhizoma Rhei (processed with wine) make up, wherein selecting the Radix Astragali for use is because of Radix Astragali sweet in the mouth, slightly warm in nature, go into the lung spleen channel, have multiple efficacies such as invigorating the spleen and replenishing QI, consolidating superficial resistance, diuretic, detumescence, poison holding, granulation promoting.The modern medicine study proof Radix Astragali has diuresis, strong, blood vessel dilating, prolongation mice rutting period and can reduce pharmacological action such as tame rabbit blood glucose.The hot flavor temperature of Rhizoma Chuanxiong; Go into the liver and gall warp; The function that activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain are arranged.Modern medicine study proof Rhizoma Chuanxiong has blood pressure lowering, the central nervous system is had sedation.Flos Carthami nature and flavor suffering, temperature; Go into the heart, Liver Channel; Promoting blood circulation to restore menstrual flow, blood stasis removing analgesic function are arranged.Modern medicine study proof Flos Carthami has the effect of coronary artery dilating and blood fat reducing.The Rhizoma Polygonati nature and flavor are sweet flat; Go into spleen, lung, kidney channel; Function with invigorating the spleen and replenishing QI, profit cardiopulmonary, bone and muscle strengthening.Modern medicine study proof Rhizoma Polygonati has the effect of antibacterium, antifungal, blood pressure lowering.Rhizoma Curcumae nature and flavor toil, temperature; Go into liver, spleen channel; Circulation of qi promoting, removing blood stasis, removing food stagnancy, analgesic function are arranged.Modern medicine study finds that Rhizoma Curcumae has antitumor, antimicrobial effect, and is similar to Rhizoma Zingiberis Recens to gastral effect.Radix et Rhizoma Rhei (processed with wine) nature and flavor hardship, cold; Go into stomach, large intestine, Liver Channel; Have that the poison that purges heat, removing mass stagnate, the function of clots absorbing blood.Modern medicine study finds that Radix Et Rhizoma Rhei has effects such as rushing down following, antibiotic, antitumor.The present invention makes each efficacy of drugs produce synergism these drug regimens, thereby can effectively delay people's senescence process.
Medicine of the present invention also can make up to reach better therapeutic with Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Fructus Psoraleae, Fructus Aurantii Immaturus.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components all has better curative effect in the following weight parts scope:
Radix Astragali 15-100 part, Rhizoma Chuanxiong 3-50 part, Semen Persicae 3-30 part, Flos Carthami 3-30 part, Rhizoma Polygonati 9-60 part, Rhizoma Curcumae 3-30 part and Radix et Rhizoma Rhei (processed with wine) 5-50 part.
Be preferably: Radix Astragali 30-90 part, Rhizoma Chuanxiong 10-20 part, Semen Persicae 5-15 part, Flos Carthami 5-15 part, Rhizoma Polygonati 15-45 part, Rhizoma Curcumae 3-10 part and Radix et Rhizoma Rhei (processed with wine) 5-15 part.
Each amounts of components of medicine of the present invention can also be Radix Astragali 15-100 part, Radix Angelicae Sinensis 3-50 part, Rhizoma Chuanxiong 3-50 part, Radix Paeoniae Rubra 3-50 part, Semen Persicae 3-30 part, Flos Carthami 3-30 part, Pheretima 3-30 part, Rhizoma Polygonati 9-60 part, Fructus Psoraleae 3-50 part, Rhizoma Curcumae 3-30 part, Fructus Aurantii Immaturus 3-30 part and Radix et Rhizoma Rhei (processed with wine) 5-50 part.
Be preferably: Radix Astragali 30-90 part, Radix Angelicae Sinensis 10-20 part, Rhizoma Chuanxiong 10-20 part, Radix Paeoniae Rubra 10-20 part, Semen Persicae 5-15 part, Flos Carthami 5-15 part, Pheretima 5-15 part, Rhizoma Polygonati 15-45 part, Fructus Psoraleae 5-15 part, Rhizoma Curcumae 3-10 part, Fructus Aurantii Immaturus 3-10 part and Radix et Rhizoma Rhei (processed with wine) 5-15 part.
More preferably: 2 parts of 12 parts of the Radixs Astragali, 3 parts of Radix Angelicae Sinensis, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Paeoniae Rubra, 2 parts in Semen Persicae, 2 parts on Flos Carthami, 2 parts of Pheretimas, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Psoraleaes, 1 part of Rhizoma Curcumae, 1 part of Fructus Aurantii Immaturus and Radix et Rhizoma Rhei (processed with wine).
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously can be made powder or capsule is taken; Can also be with these crude drug decocting together, the condensed water decocting liquid is made then.
The preparation method of preferred medicine activity component of the present invention:
Above-mentioned crude drug is quantitatively taken by weighing by described weight proportion, clean, decoct with water the back and in medicinal liquid, add 90%-95% ethanol, place and make its precipitation; Get supernatant, the active component that ethanol promptly gets medicine of the present invention is removed in the supernatant distillation.
Medicine activity component of the present invention can add various conventional adjuvant required when preparing different dosage form, as disintegrating agent, lubricant, binding agent etc., method of Chinese medicinal with routine is prepared into any peroral dosage form, as pill, powder (electuary), tablet, capsule, oral liquid etc.
Chinese medicinal formulae of the present invention is followed people's old and feeble rule, catch the old and feeble both macro and micro factor that causes, improve people's circulation and microcirculation, blood circulation promoting and blood stasis dispelling, reduce intracellular free radical and concentration of narmful substance, reduce the absorption of intestinal, from the pathology process of three aspect blocking-up or slow down aging to harmful substance.This also is the difference of this prescription and other defying age prescriptions.The present invention also can be used as the auxiliary treatment of old common disease, frequently-occurring disease.
The specific embodiment
Further specify the present invention by the following examples, but can not be used to limit protection scope of the present invention.
Embodiment 1; Medicinal granule of the present invention
Take by weighing the Radix Astragali 15 grams, Rhizoma Chuanxiong 45 grams, Semen Persicae 5 grams, Flos Carthami 30 grams, Rhizoma Polygonati 30 grams, Rhizoma Curcumae 10 grams and 40 gram Radix et Rhizoma Rhei (processed with wine), clean, decoct with water 2 times, each amount of water was not advisable to have powder, merge 2 times decoction liquor, filter, filtrate adds 90% ethanol and carries out precipitate with ethanol, reclaim ethanol and concentrated, dry under 50 ℃, it is ground into powder, add ethanol and make adhesive, add starch and make filler, be pressed into granule.
Embodiment 2: medicinal tablet of the present invention
Take by weighing the Radix Astragali 80 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Chuanxiong 15 grams, Radix Paeoniae Rubra 20 grams, Semen Persicae 10 grams, Flos Carthami 8 grams, Pheretima 12 grams, Rhizoma Polygonati 20 grams, Fructus Psoraleae 15 grams, Rhizoma Curcumae 5 grams, Fructus Aurantii Immaturus 8 grams and 10 gram Radix et Rhizoma Rhei (processed with wine).Clean, decoct with water secondary, add 3 times of amounts of water for the first time, decocted 1 hour, add 1.5 times of amounts of water for the second time, decoct half an hour, merge the secondary decoction liquor, filter, concentrate, concentrated solution adds 90% ethanol, staticly settles 1 hour; Get supernatant, supernatant distilled with alembic, remove ethanol and concentrate, 50 ℃ dry down, it is ground into powder, add adjuvant and make granule, dry, compacting is in flakes.
Embodiment 3: medicine instant of the present invention (weight portion)
Take by weighing 2 parts of 12 parts of the Radixs Astragali, 3 parts of Radix Angelicae Sinensis, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Paeoniae Rubra, 2 parts in Semen Persicae, 2 parts on Flos Carthami, 2 parts of Pheretimas, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Psoraleaes, 1 part of Rhizoma Curcumae, 1 part of Fructus Aurantii Immaturus and Radix et Rhizoma Rhei (processed with wine).Clean, decoct with water secondary, add 3 times of amounts of water for the first time, decocted 1 hour, add 1.5 times of amounts of water for the second time, decoct half an hour, merge the secondary decoction liquor, filter, concentrate, concentrated solution adds 95% ethanol, staticly settles 1 hour; Get supernatant, supernatant is distilled with alembic, remove ethanol and concentrated, dry under 50 ℃, it is ground into powder, add adjuvant and make electuary.
Test example: the clinical observation of medicine of the present invention
Clinical trial: the applicant controls the patient that senile symptom is arranged by outpatient service or ward with medicine of the present invention
Treat and follow the tracks of, its therapeutic effect obviously and have no adverse reaction.Below be some cases and effect.
37 examples: 1 routine male 46 years old, all the other 60-81 year, the men and women is even to be had.Drug usage of the present invention: three times on the one, each 60g (crude drug amount), for oral administration.14 days courses of treatment, logotype 1-6 course of treatment
Wherein:
Cerebral hemorrhage 2 examples go out the clot soak time obviously faster than general treatment
Cerebral thrombosis 3 routine thrombosis all absorb
Cardiovascular disease such as hypertension, atherosclerosis there is the auxiliary treatment effect.
The slight aphasia of cerebral infarction 1 example, upper limb muscular strength weaken transference cure after the medication
Intracerebral hematoma 2 routine hematoma all absorb
Hypertension 8 routine dizziness and blurred vision, tinnitus deafness, poor sleep, diet are bad, not endurance, uncomfortable in chest out of breath, forgetful, defecation is smooth or symptom such as constipation has clear improvement.
Atherosclerosis 6 examples had palpitation symptom out of breath, even uncomfortable in chest is obviously improved
Senilism 1 example (male 46 years old) poor sleep, diet be bad, not endurance, soreness of the waist and knees, forgetful transference cure
Old-slow-bronchial tube 6 example out of breath, poor sleep uncomfortable in chest, diet are bad, the smooth symptom of defecation is obviously improved
Dilated cardiomyopathy 2 example uncomfortable in chest out of breath, endurance, the bad symptom of diet are not obviously improved
Neurosis 6 example dizzinesses, poor sleep, bad, obviously improvement or the disappearance of endurance, cold perspiration symptom of diet
The clinical trial surface, the dizziness and blurred vision of middle-aged and elderly people of the present invention, tinnitus deafness, poor sleep, diet be bad, not endurance, soreness of the waist and knees, uncomfortable in chest out of breath, forgetful, defecation is smooth or constipation etc. has clear improvement.Cardiovascular disease such as hypertension, atherosclerosis there is the auxiliary treatment effect.
Claims (6)
1. a delay aging drug medicine is characterized in that being made by following raw medicaments in portion by weight: 15-100 part Radix Astragali, 3-50 part Rhizoma Chuanxiong, 3-30 part Semen Persicae, 3-30 part Flos Carthami, 9-60 part Rhizoma Polygonati, 3-30 part Rhizoma Curcumae and 5-50 part Radix et Rhizoma Rhei (processed with wine).
2. medicine according to claim 1 is characterized in that: the parts by weight of raw materials used medicine are Radix Astragali 30-90 part, Rhizoma Chuanxiong 10-20 part, Semen Persicae 5-15 part, Flos Carthami 5-15 part, Rhizoma Polygonati 15-45 part, Rhizoma Curcumae 3-10 part and Radix et Rhizoma Rhei (processed with wine) 5-15 part.
3. medicine according to claim 1 is characterized in that its crude drug also has 3-50 part Radix Angelicae Sinensis, 3-50 part Radix Paeoniae Rubra, 3-30 part Pheretima, 3-50 part Fructus Psoraleae and 3-30 part Fructus Aurantii Immaturus.
4. medicine according to claim 2 is characterized in that its crude drug also has Radix Angelicae Sinensis 10-20 part, Radix Paeoniae Rubra 10-20 part, Pheretima 5-15 part, Fructus Psoraleae 5-15 part, Fructus Aurantii Immaturus 3-10 part.
5. according to claim 1 or 2 or 3 or 4 described medicines, it is characterized in that: raw materials used medicine and parts by weight are 2 parts of 12 parts of the Radixs Astragali, 3 parts of Radix Angelicae Sinensis, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Paeoniae Rubra, 2 parts in Semen Persicae, 2 parts on Flos Carthami, 2 parts of Pheretimas, 6 parts of Rhizoma Polygonatis, 2 parts of Fructus Psoraleaes, 1 part of Rhizoma Curcumae, 1 part of Fructus Aurantii Immaturus and Radix et Rhizoma Rhei (processed with wine).
6. the preparation method of the described medicine of claim 1 is characterized in that: above-mentioned crude drug is quantitatively taken by weighing by described weight proportion, clean, decoct with water the back and add 90%-95% ethanol in medicinal liquid, place and make its precipitation; Get supernatant, the supernatant distillation is removed ethanol promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100198475A CN100333780C (en) | 2005-11-21 | 2005-11-21 | Chinese medicine for antisenility and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100198475A CN100333780C (en) | 2005-11-21 | 2005-11-21 | Chinese medicine for antisenility and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1785401A CN1785401A (en) | 2006-06-14 |
| CN100333780C true CN100333780C (en) | 2007-08-29 |
Family
ID=36783069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100198475A Expired - Fee Related CN100333780C (en) | 2005-11-21 | 2005-11-21 | Chinese medicine for antisenility and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100333780C (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279073A (en) * | 2000-04-17 | 2001-01-10 | 李熙德 | Antisenility Chinese medicine |
| CN1552429A (en) * | 2003-12-18 | 2004-12-08 | 西安大唐制药集团有限公司 | Chinese medicine preparation for treating senility disease |
-
2005
- 2005-11-21 CN CNB2005100198475A patent/CN100333780C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1279073A (en) * | 2000-04-17 | 2001-01-10 | 李熙德 | Antisenility Chinese medicine |
| CN1552429A (en) * | 2003-12-18 | 2004-12-08 | 西安大唐制药集团有限公司 | Chinese medicine preparation for treating senility disease |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1785401A (en) | 2006-06-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100518807C (en) | A Medicine for treatment of ascites due to cirrhosis | |
| CN102178800B (en) | Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
| CN105749179A (en) | Traditional Chinese medicine composition for treating metabolic syndrome | |
| CN103520572A (en) | Traditional Chinese composition used for treating atopic dermatitis as well as preparation method of composition | |
| CN101897821B (en) | Granular preparation for promoting blood circulation, dredging collaterals and relieving pain and preparation method as well as detection method thereof | |
| CN101011544A (en) | Gout rapid recovery pill(capsule) and preparation technique thereof | |
| CN101095768A (en) | Chinese traditional medicine capsule for treating primary hypertension for persons in middle and old age | |
| CN104524071A (en) | Pharmaceutical composition for treating primary renal disease and application thereof | |
| CN105943705A (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
| CN103330837B (en) | Traditional Chinese medicine composition for curing osteoporosis of menopausal women | |
| CN101983695A (en) | Traditional Chinese medicine composition for curing hemiplegia and preparation method thereof | |
| CN1246031C (en) | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation | |
| CN104523873A (en) | Pharmaceutical composition for treating gout | |
| CN103585414B (en) | Pharmaceutical composition for treating sciatica and osteoporosis | |
| CN103041320B (en) | Traditional Chinese medicine composition for treating cervical spondylosis and preparation method thereof | |
| CN100333780C (en) | Chinese medicine for antisenility and its preparation method | |
| CN105106634A (en) | Traditional Chinese medicine preparation for treating acute appendicitis and application thereof | |
| CN103494939A (en) | Traditional Chinese medicine for treating senile habitual constipation | |
| CN102379913B (en) | Pharmaceutical composition for treating subinvolution of uterus, and preparation method and use thereof | |
| CN103405554B (en) | A kind of medicine for the preoperative bowel relieving of abdominal operation | |
| CN110841007B (en) | Traditional Chinese medicine composition for treating cerebral apoplexy sequela and application thereof | |
| CN102178900B (en) | Lucid ganoderma and radix semiaquilegiaedecoction for treating primary biliary cirrhosis | |
| CN106139111A (en) | A kind of can effective Chinese medicine composition treating depression and preparation method thereof | |
| CN105833094A (en) | Traditional Chinese medicine composition for treating trachoma | |
| CN105327024A (en) | Traditional Chinese medicine preparation for treating rheumatoid arthritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070829 Termination date: 20101121 |