CN100335105C - Manufacturing method of cordyceps root securing promoting blood medicine - Google Patents

Abstract

The present invention relates to a manufacturing method of a cordyceps medicine for strengthening bodies and promoting blood. The cordyceps medicine is prepared from the components (A, B, C, D), wherein the component A comprises 4 to 6 of saffron crocus, 8 to 12 of cordyceps, 20 to 30 of alismatis, 23 to 35 of red sage root, 3 to 8 of hemlock parsley and 24 to 32 of leonurus; the component B comprises 3 to 8 of American ginseng, 7 to 13 of cordyceps, 30 to 45 of astragalus root, 20 to 31 of Chinese angelica, 10 to 20 of radix isatidis and 5 to 12 of earthworm; the component C comprises 22 to 32 of astragalus root, 3 to 8 of notoginseng, 15 to 23 of lonicera flower, 12 to 22 of forsythia fruit, 15 to 22 of dodder seed and 10 to 20 of cicada molting; the component D comprises 27 to 36 of dandelion, 24 to 32 of rhubarb, 22 to 33 of glabrous greenbrier rhizome and 10 to 16 of oyster shell; the components (A, B, C) are respectively pulverized into powder which is sieved by a screen with 80 to 100 meshes; the powder is filled in capsules according to the weight ratio weight proportion of 1:1:1; the component D is decocted for 30 minutes by a decocting machine, and the juice is sterilized by high temperature and is sealed for standby. The cordyceps medicine has the advantages of low cost of treatment, and small side effect, and can effectively prevent continuous deterioration of renal function and protect residual renal function.

Description

Winter, worm consolidated the manufacture method of blood circulation promoting medicine

Technical field

The present invention relates to a kind of manufacture method for the treatment of various nephritis, nephropathy and renal failure medicine.

Technical background

Show as uremia the late period of chronic renal failure (CRF), is nephropathy in a kind of common whole latter stage, and it occurs on the basis of various chronic renal essence pathological changes, occurs renal function lentamente and go down and arrive depleted.Clinical symptoms is multiple complications such as to feel sick, vomiting, weak, edema, Water-Electrolyte disorder, metabolic acidosis, late period can cause depleted fully, the serious anemia of renal function, severe infections, heart failure and cause death.And acute renal failure to be glomerular filtration rate sharply descend in a short time, creatinine clearance rate can descend in a short time and reach normally below 50%, morbidity is anxious, development is fast, the state of an illness is critical, average mortality is still up to more than 50%.100-150 people's morbidity is arranged among annual every million people group.Above-described acute renal failure and chronic kidney hypofunction, motherland's medical science is thought and is belonged to " obstruction and rejection " " difficulty in urination " " drown poison " categories such as " impairment of the kidney caused by overstrain ", majority arises from the wind heat noxious dampness, pathogenesis be nephropathy with the passing of time, negative and positive of qi and blood benefit degradation moves back, visitor's wind easily looses, damp and hot refractory holds the impairment of the spleen of a specified duration, and spleen insufficiency then accumulates to turbid damp, the not all right then pathological product of the blood stasis stasis of blood stagnates in interior, the pathomechanism that formation deficiency of vital QI, evil poison are detained; And weakened body resistance the deficient of negative and positive, QI and blood, internal organs that comprise, many, the blood stasis wet, damp and hot of evil poison, pneumatic etc. based on exopathogen, water.Clinical yang deficiency of spleen and stomache, type of deficiency of both QI and YIN, liver-kidney yin deficiency, the noxious dampness heap soil or fertilizer over and around the roots Sheng type of being divided into.Modern medicine is main Therapeutic Method with dialysis with renal transplantation still at present, its medical expense costliness, accepting hemodialysis, to keep the patient of treatment few in number, and hemodialysis can only mitigate the disease, protopathy there is not any therapeutical effect, most of patient is along with the prolongation of dialysis time, and curative effect is more and more lower.It was reported that 5 annual survival rates of cadaveric renal transplantation only are about 50% at present.The curative effect that shows renal transplantation is still not fully up to expectations.The quiet report of the Wang Zhi of traditional Chinese medical herbal treatment People's Hospital, Sichuan Prov. is 82.5% with the effective percentage of SHENSHUAINING treatment renal failure, the effective percentage of Inner Mongol hospital report JINSHUIBAO treatment chronic kidney renal failure is 61.9%, the effective percentage that Harbin City post and telecommunications hospital report Cordyceps protects unit's red treatment renal failure is 84.17%, and the effective percentage of the People's Hospital, Huizhou City, Guangdong Province report oil lamp treatment renal failure is 78.6%.

Summary of the invention

The object of the present invention is to provide a kind of medical expense low, side effect is little, can prevent effectively that renal function from continuing to worsen, and the protection residual renal function prolongs the manufacture method that its depleted nephropathy medicine winter worm consolidates blood circulation promoting medicine.

The present invention adopts following technical scheme: the present invention adopts following ratio of weight and number component: the A component: Stigma Croci 4-6, Cordyceps 8-12, Rhizoma Alismatis 20-30, Radix Salviae Miltiorrhizae 23-35, Rhizoma Chuanxiong 3-8, Herba Leonuri 24-32; B component: Radix Panacis Quinquefolii 3-8, Cordyceps 7-13, Radix Astragali 30-45, Radix Angelicae Sinensis 20-31, Radix Isatidis 10-20, Pheretima 5-12; C component: Radix Astragali 22-32, Radix Notoginseng 3-8, Flos Lonicerae 15-23, Fructus Forsythiae 12-22, Semen Cuscutae 15-22, Periostracum Cicadae 10-20; D component: Herba Taraxaci 27-36, Radix Et Rhizoma Rhei 24-32, Rhizoma Smilacis Glabrae 22-33, Concha Ostreae 10-16, above-mentioned A, B, three kinds of components of C are worn into powder respectively, after crossing the 80-100 mesh sieve, 1: 1: 1 proportioning incapsulates and gets final product by weight, after the D component is fried in shallow oil 30 minutes with boiling machine, get its juice high temperature sterilize and seal standby.

Good effect bright in this is as follows: the present invention is made up of A, B, C, the D four class Chinese medicine composition components of blood circulation promoting and blood stasis dispelling, Fuzheng Jiedu, coloclysis toxin expelling, elimination albumen and occult blood effect.

A component: blood circulation promoting and blood stasis dispelling

1. be used to improve glomerular filtration rate;

2. increase the permeability of glomerular filtration membrane, and increase the discharge of organism metabolism refuse, can be used for the too high period of blood fat of various nephropathy.Stigma Croci, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong improve the hypercoagulability of nephropathy by the blood circulation promoting and blood stasis dispelling blood vessel dilating, alleviate kidney vasospasm, and the damage that alleviates kidney.

B component: Fuzheng Jiedu

1. be used for immunologic hypofunction, deficiency of vital QI, renal anemia.

2. with the passing of time the renal anemia that various nephropathy cause, nephropathy make allomeric function all obviously descend, and the Radix Panacis Quinquefolii YIN nourishing and QI supplementing is recovered body healthy energy and immunologic function, and Cordyceps can improve renal function and improve cellular immune function, reduces blood urea nitrogen, creatinine; The Radix Astragali can promote organism immune response, improves the function of cellular immunization and humoral immunization, promote the damage of glomerular basement membrane is repaired in antigenic removing, and Radix Astragali QI invigorating, Radix Angelicae Sinensis hemopoietic, invisible gas can speed be given birth to tangible blood, improves the nephropathy anemia state.

C component: eliminate albuminuria and occult blood effect

1. it is persistent to be used for albumen and occult blood that various nephropathy cause;

2. Flos Lonicerae, Fructus Forsythiae not only have stronger antibacterial action, and have the effect of good elimination urine protein, Radix Notoginseng to have hemostasis not stay the stasis of blood can effectively eliminate occult blood.The effective antagonism body of Semen Cuscutae energy is used the dependency behind the hormone, and finally breaks away from hormone.

D component: coloclysis toxin expelling

1. be used for the heavier patient that can not take medicine of renal failure later stage nausea and vomiting;

2. Radix Et Rhizoma Rhei can be corrected renal failure patient lipid metabolic disorder, improves the kidney microcirculation, suppresses the renal cells metabolism and increases urotoxic scavenging action, and the Concha Ostreae absorbing toxin is got rid of interior metabolism product rapidly and improved renal function.

A of the present invention, B, four kinds of components of C, D, 1 can improve glomerular filtration rate, improves the hypercoagulability blood fat reducing of nephropathy, increases the permeability of glomerular filtration membrane.2 two-ways regulation body's immunological function are improved renal function, recover the animal economy function.3 effectively eliminate albuminuria and occult blood.4 increase the discharge of organism metabolism refuse.Have the Chinese medicine toxin expelling, delay kidney depletion, reduce the dialysis number of times, have no side effect.

Medicine A of the present invention, B, three kinds of combinations of C component are worn into and are dressed up capsule after powder is crossed the 80-100 mesh sieve, oral every day twice, each 5-6 gram, (can adorn 10 balls) sooner or later each once, each 100 milliliters of D component, every day secondary, retention enema half an hour, the associating utilization can recover renal function, increases that glomerular filtration membrane is penetrating analyses, improve glomerular filtration rate, reduce creatinine and blood urea nitrogen, correct acidosis, eliminate albuminuria and occult blood.Also can divide list to improve glomerular filtration rate, change the hypercoagulability of nephropathy, blood fat reducing with the A component.The B component increases Abwehrkraft des Koepers, effectively improves renal anemia, improves content of hemoglobin.The C component eliminates albuminuria and occult blood replaces hormone.The rapid toxin expelling of D component, it is stronger to reduce creatinine and blood urea nitrogen effect.

Medicine of the present invention is applicable to acute or chronic renal failure, uremia, and nephrotic syndrome, IgA nephropathy, lupus nephritis, henoch Schonlein purpura nephritis, various nephropathy nephritis all can be used.Medicine of the present invention can effectively improve therapeutic effect, alleviates patient's actual burden, improves patients ' life quality.Vast amount of clinical that I pass through has been accepted 112 routine patients for medical treatment in 3 years, all cases all meet diagnostic criteria.Curative effect is as follows: cure 36 examples in 112 examples, and effective 63 examples, invalid 13 examples, total effective rate is 88.39%, blood urea nitrogen BUN is respectively 26.41 ± 6.32 before and after the treatment; 15.22 ± 7.4 (mmol/L); Be respectively 660.12 ± 37.84 before and after the creatinine Scr treatment; 204.25 ± 40.09 (umo/L); P＞0.01.

The specific embodiment

Below in conjunction with embodiment the present invention is described in detail:

Embodiment 1: adopt following ratio of weight and number component: the A component: Stigma Croci 6, Cordyceps 8, Rhizoma Alismatis 30, Radix Salviae Miltiorrhizae 23, Rhizoma Chuanxiong 3, Herba Leonuri 32; B component: Radix Panacis Quinquefolii 8, Cordyceps 7, the Radix Astragali 45, Radix Angelicae Sinensis 20, Radix Isatidis 10, Pheretima 5; C component: the Radix Astragali 22, Radix Notoginseng 8, Flos Lonicerae 15, Fructus Forsythiae 17, Semen Cuscutae 15, Periostracum Cicadae 15; D component: Herba Taraxaci 27, Radix Et Rhizoma Rhei 28, Rhizoma Smilacis Glabrae 22, Concha Ostreae 16.Above-mentioned A, B, three kinds of components of C are worn into powder respectively, and behind 100 mesh sieves, 1: 1: 1 proportioning incapsulates and gets final product by weight excessively.After the D component is fried in shallow oil 30 minutes with boiling machine, get its juice high temperature sterilize and seal standby.

Embodiment 2: adopt following ratio of weight and number component: the A component: Stigma Croci 5, Cordyceps 10, Rhizoma Alismatis 20, Radix Salviae Miltiorrhizae 28, Rhizoma Chuanxiong 8, Herba Leonuri 28; B component: Radix Panacis Quinquefolii 5, Cordyceps 9, the Radix Astragali 38, Radix Angelicae Sinensis 25, Radix Isatidis 15, Pheretima 8; C component: the Radix Astragali 25, Radix Notoginseng 5, Flos Lonicerae 18, Fructus Forsythiae 22, Semen Cuscutae 19, Periostracum Cicadae 20; D component: Herba Taraxaci 31, Radix Et Rhizoma Rhei 24, Rhizoma Smilacis Glabrae 29, Concha Ostreae 13.Above-mentioned A, B, three kinds of components of C are worn into powder respectively, and behind 80 mesh sieves, 1: 1: 1 proportioning incapsulates and gets final product by weight excessively.After the D component is fried in shallow oil 30 minutes with boiling machine, get its juice high temperature sterilize and seal standby.

Embodiment 3: adopt following ratio of weight and number component: the A component: Stigma Croci 4, Cordyceps 12, Rhizoma Alismatis 25, Radix Salviae Miltiorrhizae 35, Rhizoma Chuanxiong 5, Herba Leonuri 24; B component: Radix Panacis Quinquefolii 3, Cordyceps 13, the Radix Astragali 30, Radix Angelicae Sinensis 31, Radix Isatidis 20, Pheretima 12; C component: the Radix Astragali 32, Radix Notoginseng 3, Flos Lonicerae 23, Fructus Forsythiae 12, Semen Cuscutae 22, Periostracum Cicadae 10; D component: Herba Taraxaci 36, Radix Et Rhizoma Rhei 32, Rhizoma Smilacis Glabrae 33, Concha Ostreae 10.Above-mentioned A, B, three kinds of components of C are worn into powder respectively, and behind 90 mesh sieves, 1: 1: 1 proportioning incapsulates and gets final product by weight excessively.After the D component is fried in shallow oil 30 minutes with boiling machine, get its juice high temperature sterilize and seal standby.

Claims (1)

1, worm consolidates the manufacture method of blood circulation promoting medicine a kind of winter, it is characterized in that adopting following ratio of weight and number component: the A component: Stigma Croci 4-6, Cordyceps 8-12, Rhizoma Alismatis 20-30, Radix Salviae Miltiorrhizae 23-35, Rhizoma Chuanxiong 3-8, Herba Leonuri 24-32; B component: Radix Panacis Quinquefolii 3-8, Cordyceps 7-13, Radix Astragali 30-45, Radix Angelicae Sinensis 20-31, Radix Isatidis 10-20, Pheretima 5-12; C component: Radix Astragali 22-32, Radix Notoginseng 3-8, Flos Lonicerae 15-23, Fructus Forsythiae 12-22, Semen Cuscutae 15-22, Periostracum Cicadae 10-20; D component: Herba Taraxaci 27-36, Radix Et Rhizoma Rhei 24-32, Rhizoma Smilacis Glabrae 22-33, Concha Ostreae 10-16; Above-mentioned A, B, three kinds of components of C are worn into powder respectively, and behind the 80-100 mesh sieve, 1: 1: 1 proportioning incapsulates and gets final product by weight excessively, after the D component is fried in shallow oil 30 minutes with boiling machine, gets its juice high temperature sterilize and seals standby.