CN105999129A - Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof - Google Patents

Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof Download PDF

Info

Publication number
CN105999129A
CN105999129A CN201610631483.4A CN201610631483A CN105999129A CN 105999129 A CN105999129 A CN 105999129A CN 201610631483 A CN201610631483 A CN 201610631483A CN 105999129 A CN105999129 A CN 105999129A
Authority
CN
China
Prior art keywords
rhizoma
radix
calcined
renal failure
chinese prescription
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610631483.4A
Other languages
Chinese (zh)
Inventor
郑贤文
尹崇福
张翼
张淑云
周光华
李萌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610631483.4A priority Critical patent/CN105999129A/en
Publication of CN105999129A publication Critical patent/CN105999129A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a traditional Chinese medicinal composition used for treating renal failure. The traditional Chinese medicinal composition comprises unprocessed rheum officinale, Glabrous Greenbrier Rhizome, Salvia miltiorrhiza, Weeping Forsythia, baked Amur Corktree Bark, Lophatherum gracile, Cogongrass rhizome, corn silk, bamboo shavings, ginger processed pinellia, Rhizoma Curcumae, sophora flower, periostracum cicadae, radix paeoniae rubra, calcined dragon bone, calcined oyster shell, Cortex Moutan, Fructus Gardeniae and licorice root. The traditional Chinese medicinal composition has the efficacy of invigorating spleen, clearing heat, transforming dampness, invigorating blood circulation, detoxifying and descending turbidity, and is suitable for treating toxin induced qi activity disorder ascending and descending disorder, turbid qi attacking internal organ induced epigastric fullness, appetite loss and spleen and kidney qi deficiency, and clinic test proves that the traditional Chinese medicinal composition has good curative effects on renal failure and exhaustion.

Description

A kind of Chinese prescription for renal failure and preparation method thereof
Technical field
The present invention relates to field of traditional Chinese medicine technology, particularly relate to a kind of Chinese prescription for renal failure and preparation method thereof.
Background technology
Modern medicine is thought, renal failure and exhaustion are to be deteriorated by various constitutionales or subsequent chronic kidney disease sustainable development, Progressive symmetric erythrokeratodermia and caused nephron seriously to damage, and finally make the clinical syndrome that body gets muddled at aspects such as excretion metabolism refuse and regulation water, electrolyte and acid-base balances.
The basic pathogenesis of chronic renal failure: it is burnt for mark that deficiency of spleen and stomach is this, turbid poison blood stasis, noxious dampness fill the air three.Chronic renal failure is divided into 5 stages, i.e. kidney compensatory phase, Decompensated stage, azotemia phase, renal failure stage and Uremic the most clinically according to renal function injury.Though Chinese medicine is without the name of disease of " chronic renal failure ", but pass through and from the point of view of clinical disease feature from its course of disease, chronic renal failure belongs to the categories such as the traditional Chinese medical science " asthenia ", " edema ", " vomiting ", " obstruction and rejection ", " lumbago ", " difficulty in urination ", and its pathogenesis is that vital QI being weakened and pathogen being violent has become common recognition.Weakened body resistance include gas, blood, yin, yang deficient, excess pathogen is turbid damp, noxious water and blood stasis.The traditional Chinese medical science thinks that chronic renal failure morbidity has inside and outside two aspect factors, and endogenous cause of ill is mainly deficiency of spleen and stomach;Exopathogenic factor mostly is six evils, skin sore, nephrotoxic drugs infringement kidney, or mistake and controls wrong treatment, occurs that spleen kidney yin sun is feeble and exhausted, and the deficiency of vital energy is not changed, and accumulates in causing turbid damp poison heresy.Owing to insufficiency of kidney-YANG is micro-, water liquid disturbance in functioning of QI;Spleen sun declines pole, sun not removing dampness, endogenous damp formation.Clear YANG failing to ascend, turbid YIN failing to descend, then smoked in turbid damp poison heresy, disease sees oliguria or anuria, dirty smelly in mouth, or has urine taste, and thick fur is greasy;The evil excessive skin of turbid damp poison, disease sees that skin pruritus, body are sent out desolation or have white sample to separate out;Pale tongue has that indentation, tongue be the most greasy, soft and thready pulse be expectorant turbid check as;Upward adverse flow of phlegm, blinds thinking, therefore has drowsiness god to stay, soliloquy or in silence, even coma is not waken up.
Chronic renal failure is the disease that serious harm people's life is healthy, and along with aged tendency of population and the raising of health care level, primary disease sickness rate is in raising trend year by year in recent years.China there is no the definite statistics of chronic renal failure incidence rate, and Patients With Kidney Diseases occurs chronic impaired regardless of the cause of disease, such as renal function, the most irreversible, total being by property of trend increases the weight of, and glomerular filtration rate is gradually reduced, to renal function total loss.But different pathogeny, and with or without complication, particularly in, early stage patient, its renal function reduces speed can be had significantly different, some can stablizing in the long period, some can improvement in a period of time.
Chronic renal failure pathogenesis is the most numerous and diverse, changeful, therefore when facing card, deficiency of spleen and stomach to be kept a firm hand on is originally and turbid poison blood stasis pents up and fills the air the three burnt keys for its pathogenesis for target pathogenesis, especially pond poison.According to the three burnt affiliated pathological changes of internal organs, clinical manifestation and change of disease relation, its card controls regular following.Chinese medicine is in treatment chronic renal failure and has been achieved for the achievement attracted people's attention in terms of delaying the clinical efficacy that residual renal function Progressive symmetric erythrokeratodermia deteriorates, and the advantage of therapy of combining Chinese and Western medicine chronic renal failure and characteristic have obtained the generally accreditation of modern medicine circle.Therefore, play Advantages of TCM and characteristic treatment chronic renal failure, have positive effect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of Chinese prescription for renal failure and preparation method thereof.
For solving above-mentioned technical problem, the technical solution used in the present invention is as follows.
A kind of Chinese prescription for renal failure, this Chinese prescription comprises following pharmacodynamic raw materials: Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis, Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Curcumae, Flos Sophorae, Periostracum Cicadae, Radix Paeoniae Rubra, Os Draconis (calcined), Concha Ostreae (calcined), Cortex Moutan, SHANZHIZI, Radix Glycyrrhizae.
As a preferred technical solution of the present invention, this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 15-25, Rhizoma Smilacis Glabrae 20-30, Radix Salviae Miltiorrhizae 30-45, Fructus Forsythiae 15-20, Cortex Phellodendri (parched) 20-25, Herba Lophatheri 25-30, Rhizoma Imperatae 50-65, Stigma Maydis 30-40, Caulis Bambusae In Taenia 20-30, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15-20, Rhizoma Curcumae 9-12, Flos Sophorae 20-30, Periostracum Cicadae 10-18, Radix Paeoniae Rubra 12-18, Os Draconis (calcined) 30-45, Concha Ostreae (calcined) 30-45, Cortex Moutan 9-12, SHANZHIZI 10-18, Radix Glycyrrhizae 6-10.
As a preferred technical solution of the present invention, this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 20, Rhizoma Smilacis Glabrae 25, Radix Salviae Miltiorrhizae 38, Fructus Forsythiae 18, Cortex Phellodendri (parched) 22, Herba Lophatheri 28, Rhizoma Imperatae 58, Stigma Maydis 35, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 25, Periostracum Cicadae 14, Radix Paeoniae Rubra 15, Os Draconis (calcined) 38, Concha Ostreae (calcined) 36, Cortex Moutan 10, SHANZHIZI 14, Radix Glycyrrhizae 8.
As a preferred technical solution of the present invention, this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 15, Rhizoma Smilacis Glabrae 20, Radix Salviae Miltiorrhizae 30, Fructus Forsythiae 15, Cortex Phellodendri (parched) 20, Herba Lophatheri 30, Rhizoma Imperatae 50, Stigma Maydis 30, Caulis Bambusae In Taenia 20, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 20, Periostracum Cicadae 12, Radix Paeoniae Rubra 15, Os Draconis (calcined) 30, Concha Ostreae (calcined) 30, Cortex Moutan 12, SHANZHIZI 12, Radix Glycyrrhizae 8.
As a preferred technical solution of the present invention, this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 18, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 40, Fructus Forsythiae 18, Cortex Phellodendri (parched) 25, Herba Lophatheri 25, Rhizoma Imperatae 60, Stigma Maydis 25, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15, Rhizoma Curcumae 9, Flos Sophorae 30, Periostracum Cicadae 15, Radix Paeoniae Rubra 12, Os Draconis (calcined) 35, Concha Ostreae (calcined) 35, Cortex Moutan 15, SHANZHIZI 10, Radix Glycyrrhizae 6.
As a preferred technical solution of the present invention, this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 25, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 45, Fructus Forsythiae 20, Cortex Phellodendri (parched) 25, Herba Lophatheri 30, Rhizoma Imperatae 65, Stigma Maydis 40, Caulis Bambusae In Taenia 30, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20, Rhizoma Curcumae 12, Flos Sophorae 30, Periostracum Cicadae 18, Radix Paeoniae Rubra 18, Os Draconis (calcined) 45, Concha Ostreae (calcined) 45, Cortex Moutan 12, SHANZHIZI 18, Radix Glycyrrhizae 10.
The preparation method of the above-mentioned Chinese prescription for renal failure, comprises the following steps:
A, by Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis, Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Curcumae, Flos Sophorae, Periostracum Cicadae, Radix Paeoniae Rubra, Os Draconis (calcined), Concha Ostreae (calcined), Cortex Moutan, SHANZHIZI and licorice raw material medicine in the prescription proportioning side of taking, clean, sterilizing, standby respectively;
B, step A gained medical material decoct and take decocting liquid for twice and get final product.
As a preferred technical solution of the present invention, in step B, first soak at room temperature 30 minutes before decocting for Chinese herbal medicine, then the very hot oven 10-15min that heats is to boiling, then uses slow fire instead and decoct 30 minutes, obtains a decocting liquid;The very hot oven that the most again adds water heat 10-15min to boiling, use instead slow fire decoct 30 minutes secondary decocting liquid, twice decocting liquid merges and get final product.It is poured on and mixes together, take at twice, decoct 150-200 milliliter every time.
Use and have the beneficial effects that produced by technique scheme:
The basic pathogenesis of chronic renal failure is: it is burnt for mark that deficiency of spleen and stomach is this, turbid poison blood stasis, noxious dampness fill the air three.Chronic renal failure is divided into 5 stages, i.e. kidney compensatory phase, Decompensated stage, azotemia phase, renal failure stage and Uremic the most clinically according to renal function injury.Though Chinese medicine is without the name of disease of " chronic renal failure ", but pass through and from the point of view of clinical disease feature from its course of disease, chronic renal failure belongs to the categories such as the traditional Chinese medical science " asthenia ", " edema ", " vomiting ", " obstruction and rejection ", " lumbago ", " difficulty in urination ", and its pathogenesis is that vital QI being weakened and pathogen being violent has become common recognition.Weakened body resistance include gas, blood, yin, yang deficient, excess pathogen is turbid damp, noxious water and blood stasis.The traditional Chinese medical science thinks that chronic renal failure morbidity has inside and outside two aspect factors, and endogenous cause of ill is mainly deficiency of spleen and stomach;Exopathogenic factor mostly is six evils, skin sore, nephrotoxic drugs infringement kidney, or mistake and controls wrong treatment, occurs that spleen kidney yin sun is feeble and exhausted, and the deficiency of vital energy is not changed, and accumulates in causing turbid damp poison heresy.Owing to insufficiency of kidney-YANG is micro-, water liquid disturbance in functioning of QI;Spleen sun declines pole, sun not removing dampness, endogenous damp formation.Clear YANG failing to ascend, turbid YIN failing to descend, then smoked in turbid damp poison heresy, disease sees oliguria or anuria, dirty smelly in mouth, or has urine taste, and thick fur is greasy;The evil excessive skin of turbid damp poison, disease sees that skin pruritus, body are sent out desolation or have white sample to separate out;Pale tongue has that indentation, tongue be the most greasy, soft and thready pulse be expectorant turbid check as;Upward adverse flow of phlegm, blinds thinking, therefore has drowsiness god to stay, soliloquy or in silence, even coma is not waken up.Chronic renal failure pathogenesis is the most numerous and diverse, changeful, therefore when facing card, deficiency of spleen and stomach to be kept a firm hand on is originally and turbid poison blood stasis pents up and fills the air the three burnt keys for its pathogenesis for target pathogenesis, especially pond poison.According to the three burnt affiliated pathological changes of internal organs, clinical manifestation and change of disease relation, its card controls regular following.
The drug effect principle of the present invention: 1. Radix Et Rhizoma Rhei removing toxic substances Xiezhuo Huayu, makes the heresy of turbid poison go from intestinal;2. Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis clearing away heat and eliminating dampness, the regulating the stomach and sending down the abnormal ascending QI such as Chang Peiyong Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Smilacis Glabrae, removing toxic substances dehumidifying, help monarch detoxify let out turbid;Forging Os Draconis, Concha Ostreae (calcined) convergence absorption, make heresy of internal turbid poison discharge from intestinal, benefits toxin expelling the turbid descending, Radix Salviae Miltiorrhizae, Rhizoma Curcumae, Periostracum Cicadae, Radix Paeoniae Rubra disperse blood stasis and dredge collateral, and to strengthen the merit of Radix Et Rhizoma Rhei blood stasis dispelling, the interpromoting relation in five elements that is harmonious coordination onset is thought and controlled;3. Fructus Forsythiae, Cortex Moutan, mountain clearing away heart-fire detoxification are assistant;4. Flos Sophorae Immaturus clearing away heat and cooling blood, the preventing and treating long strongly fragrant one-tenth pyretic toxicity of turbid damp is for making medicine.
The present invention has spleen invigorating clearing away heat and eliminating dampness, effect of promoting blood circulation and detoxication the turbid descending, it is adaptable to toxin causes that ascending or descending movement of vital Qi is not normal, foul smell violates the diseases such as upper abdomen distension, inappetence caused by internal organs and spleen deficiency of kidney-QI is shown in above-mentioned card marquis person.The test example that see below, clinical trial confirms that the present invention has good therapeutic effect for renal failure and exhaustion.
Detailed description of the invention
Following example are described in detail the present invention.Various raw material used in the present invention and items of equipment are conventional commercial product, all can be bought by market and directly obtain.
Embodiment 1
The pure Chinese prescription of the treatment chronic renal failure of the present embodiment is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 20, Rhizoma Smilacis Glabrae 25, Radix Salviae Miltiorrhizae 38, Fructus Forsythiae 18, Cortex Phellodendri (parched) 22, Herba Lophatheri 28, Rhizoma Imperatae 58, Stigma Maydis 35, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 25, Periostracum Cicadae 14, Radix Paeoniae Rubra 15, Os Draconis (calcined) 38, Concha Ostreae (calcined) 36, Cortex Moutan 10, SHANZHIZI 14, Radix Glycyrrhizae 8.
Its preparation method is: by Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis, Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Curcumae, Flos Sophorae, Periostracum Cicadae, Radix Paeoniae Rubra, Os Draconis (calcined), Concha Ostreae (calcined), Cortex Moutan, SHANZHIZI and licorice raw material medicine in the prescription proportioning side of taking, clean, sterilizing respectively, decocts at twice and takes decocting liquid and get final product.
Embodiment 2
The pure Chinese prescription of the treatment chronic renal failure of the present embodiment is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 15, Rhizoma Smilacis Glabrae 20, Radix Salviae Miltiorrhizae 30, Fructus Forsythiae 15, Cortex Phellodendri (parched) 20, Herba Lophatheri 30, Rhizoma Imperatae 50, Stigma Maydis 30, Caulis Bambusae In Taenia 20, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 20, Periostracum Cicadae 12, Radix Paeoniae Rubra 15, Os Draconis (calcined) 30, Concha Ostreae (calcined) 30, Cortex Moutan 12, SHANZHIZI 12, Radix Glycyrrhizae 8.Preparation method is with embodiment 1.
Embodiment 3
The pure Chinese prescription of the treatment chronic renal failure of the present embodiment is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 18, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 40, Fructus Forsythiae 18, Cortex Phellodendri (parched) 25, Herba Lophatheri 25, Rhizoma Imperatae 60, Stigma Maydis 25, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15, Rhizoma Curcumae 9, Flos Sophorae 30, Periostracum Cicadae 15, Radix Paeoniae Rubra 12, Os Draconis (calcined) 35, Concha Ostreae (calcined) 35, Cortex Moutan 15, SHANZHIZI 10, Radix Glycyrrhizae 6.Preparation method is with embodiment 1.
Embodiment 4
The pure Chinese prescription of the treatment chronic renal failure of the present embodiment is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 25, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 45, Fructus Forsythiae 20, Cortex Phellodendri (parched) 25, Herba Lophatheri 30, Rhizoma Imperatae 65, Stigma Maydis 40, Caulis Bambusae In Taenia 30, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20, Rhizoma Curcumae 12, Flos Sophorae 30, Periostracum Cicadae 18, Radix Paeoniae Rubra 18, Os Draconis (calcined) 45, Concha Ostreae (calcined) 45, Cortex Moutan 12, SHANZHIZI 18, Radix Glycyrrhizae 10.Preparation method is with embodiment 1.
Embodiment 5, the clinical trial example of the present invention
Case selection has the Symptoms last more than 6 weeks of anemia, abdominal distention, weak, nauseating, loss of appetite;Through lab testing serum creatinine 300-1000umol/L, blood urea nitrogen 20-32mmol/L, hemoglobin 70-105g/L, double kidney color ultrasounds prompting double renal hemodynamic supply degree such as not reduces, glomerular filtration rate is 12-42ml/min, except person caused by other serious organic diseases as object of study.
Patient through renal insufficiency each phase that clinical statistics is included in amounts to 120 examples.Use the blind single pair of of random packet according to test method(s).120 example renal insufficiency patients use table of random number method to be randomly divided into 2 groups.Male 40 example in treatment group (embodiment 1) 60 examples, women 20 example, age 25~65 years old.Male 35 example in matched group (traditional Chinese medicines quasi-word Chinese patent medicine NIAODUQING KELI group) 60 examples, women 25 example, age 25~63 years old.
Test group: the oral present invention decocts medicinal liquid.Three times on the one, every time corresponding crude drug 100g, the most oral, take medicine front and back avoid eating anything raw or cold, pungent, greasy food.Matched group: NIAODUQING KELI group is treated, Guangzhou Kang Cheng pharmaceutcal corporation, Ltd produces.Three times a day, each l0 milligram, take half an hour ante cibum.Continue 14 days.Take at twice, decoct 150-200 milliliter every time.
Clinical comparison result.Test group: anemia, abdominal distention, symptom weak, nauseating, loss of appetite are all improved;Check again for through laboratory, serum creatinine is down to 150-435umol/L from 300-1000umol/L, blood urea nitrogen is down to 12-15mmol/L from 20-32mmol/L, hemoglobin rises 95-125g/L from 70-105g/L, the double renal hemodynamic of double kidney color ultrasounds prompting is under-supply improvement performance, and glomerular filtration rate is to be promoted 38-55ml/min by 12-42ml/min.Matched group (NIAODUQING KELI group): anemia, abdominal distention, symptom weak, nauseating, loss of appetite improve inconspicuous (p > 0.05);Serum creatinine, blood urea nitrogen, hemoglobin L, double kidney color ultrasounds prompting double renal hemodynamic supply degree such as not reduces, and glomerular filtration rate improves inconspicuous.
Foregoing description is only used as the enforceable technical scheme of the present invention and proposes, not as the single restrictive condition to its technical scheme itself.

Claims (8)

1. the Chinese prescription for renal failure, phase each to renal insufficiency, primary and secondary uremia have the good efficacy that can verify that, it is characterised in that: this Chinese prescription comprises following pharmacodynamic raw materials: Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis, Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Curcumae, Flos Sophorae, Periostracum Cicadae, Radix Paeoniae Rubra, Os Draconis (calcined), Concha Ostreae (calcined), Cortex Moutan, SHANZHIZI, Radix Glycyrrhizae.
Chinese prescription for renal failure the most according to claim 1, it is characterised in that: this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 15-25, Rhizoma Smilacis Glabrae 20-30, Radix Salviae Miltiorrhizae 30-45, Fructus Forsythiae 15-20, Cortex Phellodendri (parched) 20-25, Herba Lophatheri 25-30, Rhizoma Imperatae 50-65, Stigma Maydis 30-40, Caulis Bambusae In Taenia 20-30, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15-20, Rhizoma Curcumae 9-12, Flos Sophorae 20-30, Periostracum Cicadae 10-18, Radix Paeoniae Rubra 12-18, Os Draconis (calcined) 30-45, Concha Ostreae (calcined) 30-45, Cortex Moutan 9-12, SHANZHIZI 10-18, Radix Glycyrrhizae 6-10.
Chinese prescription for renal failure the most according to claim 1, it is characterised in that: this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 20, Rhizoma Smilacis Glabrae 25, Radix Salviae Miltiorrhizae 38, Fructus Forsythiae 18, Cortex Phellodendri (parched) 22, Herba Lophatheri 28, Rhizoma Imperatae 58, Stigma Maydis 35, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 25, Periostracum Cicadae 14, Radix Paeoniae Rubra 15, Os Draconis (calcined) 38, Concha Ostreae (calcined) 36, Cortex Moutan 10, SHANZHIZI 14, Radix Glycyrrhizae 8.
Chinese prescription for renal failure the most according to claim 1, it is characterised in that: this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 15, Rhizoma Smilacis Glabrae 20, Radix Salviae Miltiorrhizae 30, Fructus Forsythiae 15, Cortex Phellodendri (parched) 20, Herba Lophatheri 30, Rhizoma Imperatae 50, Stigma Maydis 30, Caulis Bambusae In Taenia 20, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18, Rhizoma Curcumae 10, Flos Sophorae 20, Periostracum Cicadae 12, Radix Paeoniae Rubra 15, Os Draconis (calcined) 30, Concha Ostreae (calcined) 30, Cortex Moutan 12, SHANZHIZI 12, Radix Glycyrrhizae 8.
Chinese prescription for renal failure the most according to claim 1, it is characterised in that: this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 18, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 40, Fructus Forsythiae 18, Cortex Phellodendri (parched) 25, Herba Lophatheri 25, Rhizoma Imperatae 60, Stigma Maydis 25, Caulis Bambusae In Taenia 25, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15, Rhizoma Curcumae 9, Flos Sophorae 30, Periostracum Cicadae 15, Radix Paeoniae Rubra 12, Os Draconis (calcined) 35, Concha Ostreae (calcined) 35, Cortex Moutan 15, SHANZHIZI 10, Radix Glycyrrhizae 6.
Chinese prescription for renal failure the most according to claim 1, it is characterised in that: this Chinese prescription is counted by weight and is comprised following composition: Radix Et Rhizoma Rhei 25, Rhizoma Smilacis Glabrae 30, Radix Salviae Miltiorrhizae 45, Fructus Forsythiae 20, Cortex Phellodendri (parched) 25, Herba Lophatheri 30, Rhizoma Imperatae 65, Stigma Maydis 40, Caulis Bambusae In Taenia 30, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20, Rhizoma Curcumae 12, Flos Sophorae 30, Periostracum Cicadae 18, Radix Paeoniae Rubra 18, Os Draconis (calcined) 45, Concha Ostreae (calcined) 45, Cortex Moutan 12, SHANZHIZI 18, Radix Glycyrrhizae 10.
7. the preparation method of the Chinese prescription for renal failure described in any one of claim 1-6, it is characterised in that: the method comprises the following steps:
A, by Radix Et Rhizoma Rhei, Rhizoma Smilacis Glabrae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Cortex Phellodendri (parched), Herba Lophatheri, Rhizoma Imperatae, Stigma Maydis, Caulis Bambusae In Taenia, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Rhizoma Curcumae, Flos Sophorae, Periostracum Cicadae, Radix Paeoniae Rubra, Os Draconis (calcined), Concha Ostreae (calcined), Cortex Moutan, SHANZHIZI and licorice raw material medicine in the prescription proportioning side of taking, clean, sterilizing, standby respectively;
B, step A gained medical material decoct and take decocting liquid for twice and get final product.
The preparation method of the Chinese prescription for renal failure the most according to claim 7, it is characterised in that: in step B, first soak at room temperature 30 minutes before decocting for Chinese herbal medicine, then the very hot oven 10-15min that heats is to boiling, then uses slow fire instead and decoct 30 minutes, obtains a decocting liquid;The very hot oven that the most again the adds water 10-15min that heats, to boiling, uses slow fire instead and decocts 30 minutes to obtain secondary decocting liquid, and twice decocting liquid merges and get final product, and is poured on and mixes together, takes at twice, every time pan-fried 150-200 milliliter.
CN201610631483.4A 2016-08-04 2016-08-04 Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof Pending CN105999129A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610631483.4A CN105999129A (en) 2016-08-04 2016-08-04 Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610631483.4A CN105999129A (en) 2016-08-04 2016-08-04 Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105999129A true CN105999129A (en) 2016-10-12

Family

ID=57134330

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610631483.4A Pending CN105999129A (en) 2016-08-04 2016-08-04 Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105999129A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106880665A (en) * 2017-04-12 2017-06-23 吕慧 Treat uremic Chinese medicine toxins eliminating agent

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1359717A (en) * 2001-12-26 2002-07-24 赵广钧 Process for prepairng Chinese-medicinal ointment of treating uremia, renal hypertension and hyperlipomia
CN101085262A (en) * 2007-06-26 2007-12-12 北京艺信堂医药研究所 Traditional Chinese medicine preparation for treating chronic interstitial nephritis
CN101085319A (en) * 2007-06-26 2007-12-12 北京艺信堂医药研究所 Traditional Chinese medicine for curing chronic renal failure
CN104042968A (en) * 2014-06-24 2014-09-17 王秀红 Traditional Chinese medicinal composition for treating acute renal failure
CN105250795A (en) * 2015-11-24 2016-01-20 崔红霞 Formula of traditional Chinese medicine for treating acute pyelonephritis and preparation method thereof
CN105561024A (en) * 2014-10-15 2016-05-11 顾飞 Traditional Chinese medicine formula for treating diabetic nephropathy

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1359717A (en) * 2001-12-26 2002-07-24 赵广钧 Process for prepairng Chinese-medicinal ointment of treating uremia, renal hypertension and hyperlipomia
CN101085262A (en) * 2007-06-26 2007-12-12 北京艺信堂医药研究所 Traditional Chinese medicine preparation for treating chronic interstitial nephritis
CN101085319A (en) * 2007-06-26 2007-12-12 北京艺信堂医药研究所 Traditional Chinese medicine for curing chronic renal failure
CN104042968A (en) * 2014-06-24 2014-09-17 王秀红 Traditional Chinese medicinal composition for treating acute renal failure
CN105561024A (en) * 2014-10-15 2016-05-11 顾飞 Traditional Chinese medicine formula for treating diabetic nephropathy
CN105250795A (en) * 2015-11-24 2016-01-20 崔红霞 Formula of traditional Chinese medicine for treating acute pyelonephritis and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106880665A (en) * 2017-04-12 2017-06-23 吕慧 Treat uremic Chinese medicine toxins eliminating agent

Similar Documents

Publication Publication Date Title
CN103705843B (en) A kind of medicine for the treatment of gastropathy
CN102652826A (en) Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine particle
CN104771707A (en) Traditional Chinese medicine composition for treating chronic gastritis
CN103381266B (en) Traditional Chinese medicine for treating nervous vomiting
CN102698207A (en) Traditional Chinese medicine composition for treating hepatopathy and preparation method thereof
CN106377751A (en) Traditional Chinese medicine composition for preventing cancers
CN103100072B (en) Traditional Chinese medicine composition for treating proctitis and appendicitis, and restraining rectum cancer
CN101804171A (en) Medicine for treating gastric cancer
CN102600424B (en) Chinese herba preparation for treating nephropyelitis and preparation method of Chinese herba preparation
CN105999129A (en) Traditional Chinese medicinal composition used for treating renal failure, and preparation method thereof
CN104667249B (en) A kind of Chinese medicine composition for treating primary dysmenorrhea
CN102935214B (en) Traditional Chinese medicinal composition for treating uremia
CN102988952B (en) Umbilicus-applied nursing cream for preventing uroschesis of infant accepting surgical operation
CN102961696B (en) Chinese medicinal composition for treating diabetic nephropathy edema
CN104510937A (en) Traditional Chinese medicinal formula for treating infantile asthma and preparation method for paste of traditional Chinese medicinal formula
CN104548030A (en) Traditional Chinese medicine composition for treatment of chronic cholecystitis
CN103877484A (en) Traditional Chinese medicine oral liquid for treating oral liquid
CN104306951A (en) Traditional Chinese medicine combination for treating ascites of cirrhosis and preparing method of traditional Chinese medicine combination
CN103877384A (en) Traditional Chinese medicine preparation for treating rectal cancer and preparation method thereof
CN103751357A (en) Traditional Chinese medicine composition for treating spleen-deficiency-type colonitis
CN102698102A (en) Traditional Chinese medicament for treating chronic laryngitis
CN102727847B (en) Preparation method for Chinese herbal lotion used for treating excessive-drinking caused trichomonas vaginitis
CN102805850B (en) Preparation method of traditional Chinese medicine for treating fatigue type acute glomerulonephritis
CN102813785B (en) Preparation method of traditional Chinese medicine for treating headache-type acute glomerulonephritis
CN102805851B (en) Method for preparing traditional Chinese medicine for treating qi deficiency type acute glomerulonephritis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20161012

RJ01 Rejection of invention patent application after publication