CN105250795A - Formula of traditional Chinese medicine for treating acute pyelonephritis and preparation method thereof - Google Patents

Abstract

The invention discloses a formula of a traditional Chinese medicine for treating acute pyelonephritis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following components in parts by weight: 50-70 parts of Chinese yam, 50-65 parts of herba leonuri, 45-60 parts of radix rehmanniae recen, 45-60 parts of semen plantaginis, 40-55 parts of rhizoma atractylodis, 40-50 parts of herba houttuyniae, 40-50 parts of ephedra, 35-45 parts of lalang grass rhizome, 35-45 parts of rhizoma alismatis, 30-40 parts of selfheal, 25-40 parts of herba cepbalanoplosis segeti, 20-30 parts of cortex mori radicis, 20-30 parts of periostracum cicada, 15-30 parts of herba pyrolae, 15-25 parts of fructus forsythiae and 10-25 parts of poria cocos. The traditional Chinese medicine is prepared from the medicinal materials according to the principle of monarch, minister, assistant and guide, is prescribed according to interior dampness-heat, water-damp failure in transformation, kidney-yin deficiency and other causes, has the effects of clearing heat, removing toxicity, nourishing yin and inducing diuresis, and has good absorption effect, remarkable curative effect, no toxic or side effect and no clinical adverse effect. Clinical application verifies that the traditional Chinese medicine has a relatively high cure rate on acute pyelonephritis.

Description

A kind of Chinese prescription and preparation method being used for the treatment of acute pyelitis

Art

The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese prescription and the preparation method that are used for the treatment of acute pyelitis.

Background technology

Acute renal glomerulus pyelitis is called for short acute pyelitis, because cause of disease difference has person to be acute pyelitis syndrome.It is one group of Acute onset, because premunition reacts the diffusivity glomerule apyetous inflammatory lesion caused.Clinically with edema, oliguria, hematuria and hypertension for main manifestations, sick child's premorbid often has the antecedent diseases such as flu, tonsillitis or skin purulent infection, and primary disease is modal a kind of kidney disease in children's's period.Be common in 3-8 year child, within less than 2 years old, seldom see.Prognosis is generally good, and the course of disease is 6 months to 1 year, develops into chronic pyelitis person only only a few.Within 1 week, serious symptoms can be there is, as hypertensive encephalopathy, renal insufficiency, heart failure etc., so should pay close attention to primary disease in minority infant in morbidity.

At present, doctor trained in Western medicine is for the Therapeutic Method of acute pyelitis: light-duty case is with the blue or green enzyme element of intramuscular injection or other effective antibiotics; Model case still needs symptomatic treatment as blood pressure lowering, diuresis etc.; Severe cases based on prevention and corntrol serious symptoms, such as quiet note furosemide and stable, quiet sodium nitroprusside, phentolamine etc.Above-mentioned Therapeutic Method can only mitigate the disease, controls serious symptoms, can not thoroughly cure.

Summary of the invention

The invention provides a kind of Chinese prescription and the preparation method that are used for the treatment of acute pyelitis, there is effect of heat-clearing and toxic substances removing, YIN nourishing, heat clearing away, diuretic, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to acute pyelitis cure rate through clinical verification.

For achieving the above object, technical scheme of the present invention is implemented as follows:

Raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 50 ~ 70 parts of Herba Leonuris 50 ~ 65 parts of Radix Rehmanniae 45 ~ 60 portions of Semen Plantaginiss 45 ~ 60 parts

Rhizoma Atractylodis 40 ~ 55 parts of Herba Houttuyniae 40 ~ 50 portions of Herba Ephedraes 40 ~ 50 parts of Rhizoma Imperataes 35 ~ 45 parts

Rhizoma Alismatis 35 ~ 45 parts of Spica Prunellaes 30 ~ 40 portions of Herba Cirsiis 25 ~ 40 parts of Cortex Mori 20 ~ 30 parts

10 ~ 25 parts, Periostracum Cicadae 20 ~ 30 portions of Herba Pyrolaes 15 ~ 30 parts of Fructus Forsythiaes 15 ~ 25 parts of Poria

Raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 55 ~ 65 parts of Herba Leonuris 55 ~ 65 parts of Radix Rehmanniae 50 ~ 60 portions of Semen Plantaginiss 50 ~ 60 parts

Rhizoma Atractylodis 45 ~ 50 parts of Herba Houttuyniae 45 ~ 50 portions of Herba Ephedraes 45 ~ 50 parts of Rhizoma Imperataes 40 ~ 45 parts

Rhizoma Alismatis 40 ~ 45 parts of Spica Prunellaes 35 ~ 40 portions of Herba Cirsiis 30 ~ 40 parts of Cortex Mori 25 ~ 30 parts

15 ~ 25 parts, Periostracum Cicadae 25 ~ 30 portions of Herba Pyrolaes 20 ~ 30 parts of Fructus Forsythiaes 20 ~ 25 parts of Poria

Raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 60 parts of Herba Leonuris 60 parts of Radix Rehmanniae 55 portions of Semen Plantaginiss 55 parts

Rhizoma Atractylodis 48 parts of Herba Houttuyniae 48 portions of Herba Ephedraes 46 parts of Rhizoma Imperataes 42 parts

Rhizoma Alismatis 42 parts of Spica Prunellaes 48 portions of Herba Cirsiis 35 parts of Cortex Mori 28 parts

20 parts, Periostracum Cicadae 26 portions of Herba Pyrolaes 25 parts of Fructus Forsythiaes 22 parts of Poria

Preparation method comprises following processing step:

(1) Rhizoma Dioscoreae slow fire stir-fry is ground into powder to the micro-Huang of epidermis, cross 120 order fine powders, for subsequent use.

(2) Herba Ephedrae pulverizing is ground into powder, cross 120 order fine powders, for subsequent use.

(3) Rhizoma Alismatis is stir-fried with high heat and grind into powder after epidermis is golden yellow for several times, cross 120 order fine powders, for subsequent use.

(4) Herba Leonuri, Periostracum Cicadae, the Radix Rehmanniae, Semen Plantaginis, Rhizoma Atractylodis, Rhizoma Imperatae, Herba Houttuyniae are put into container, add the water of six times amount, soak after 3 ~ 5 hours, get immersion in remaining medicinal residues, add triplication again; Water, soaks after 1 ~ 2 hour, gets immersion; Merge twice gained immersion, under simmer down to 55 DEG C of environment, the thick paste of relative density 1.15 ~ 1.20, for subsequent use.

(5) Spica Prunellae, Fructus Forsythiae, Poria, Herba Pyrolae, Cortex Mori, Herba Cirsii are put into container, add the shao-hsing rice wine of qdx, boil rear continuation immersion and get immersion after 2 ~ 4 hours; In remaining medicinal residues, add the shao-hsing rice wine of doubling dose again, soak after 1 ~ 1.5 hour under room temperature, get immersion; Merge twice immersion, under simmer down to room temperature environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use.

(6) by the fine powder of step (1), step (2), step (3) gained, the thick paste obtained with step (4), step (5) mixes, add after refined honey stirs, be prepared as the tablet of 0.15g/ sheet.

The property of medicine of the present invention's Chinese medicine used is as follows:

Rhizoma Dioscoreae: sweet in the mouth; Property is put down.Enter lung; Spleen; Kidney channel.Spleen reinforcing; Support lung; Reinforce the kidney; Benefit essence.Cure mainly diarrhea due to hypofunction of the spleen; Lack of appetite edema; Cough and asthma due to lung deficiency; Quench one's thirst; Seminal emission; Leukorrhagia; To suffer from a deficiency of the kidney frequent micturition; Carbuncle is controlled in external; Scrofula." book on Chinese herbal medicine just " carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, control weakness, treat five kinds of strain and seven kinds of impairment." modern medicine study confirms, Rhizoma Dioscoreae can reduce blood glucose, regulates body to non-specific irritant reaction, and effectively the Immunosuppression effect of antagonism cyclophosphamide, stimulates intestinal motility, promotes that intestinal contents is emptying, in addition can also aid digestion, antidiarrheal, eliminate the phlegm.

Herba Leonuri: acrid in the mouth; Bitter; Property micro-enter.Return liver; Kidney; Pericardium channel.Promoting blood flow to regulate menstruation; Inducing diuresis to remove edema; Heat-clearing and toxic substances removing.Cure mainly menoxenia; Amenorrhea; Vaginal bleeding during pregnancy is had difficult labour; Retention of placenta; Puerperal blood faints; Abdominal pain due to blood stasis; Traumatic injury; Dysuria; Edema; Carbuncle skin infection." book on Chinese herbal medicine is looked for the truth " carries: " disappear water promoting the circulation of blood, removes crazy tissue regeneration promoting, and regulating menstruation is detoxified, for wanting agent after tire front tyre." modern medicine study shows; the leonurines contained by Herba Leonuri etc. have excitation to uterus; antiplatelet aggregation, coagulation; improve coronary circulation, cardioprotection; strengthen cardiac contractile force; direct excited respiratory center, slow intestinal tube tonicity of speeding, and also have the effect such as CNS inhibition, bacteriostatic in addition.

The Radix Rehmanniae: sweet in the mouth; Bitter; Cold nature.GUIXIN; Liver; Kidney channel.Nourishing YIN and clearing away heat; Removing heat from blood is enriched blood.Cure mainly heat and have heart tonifying, diuresis, blood pressure lowering, blood sugar lowering, protect the liver, the pharmacological action such as antibacterial, hemocytes increasing.

Semen Plantaginis: sweet in the mouth; Light; Cold nature.Return lung; Liver; Kidney; Urinary bladder channel.Clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily." Japan hanako materia medica " carries: " diuresis drenches puckery, tonifying YANG.Control de-essence, vexed, the therapeutic method to keep the adverse QI flowing downwards." modern medicine study confirmation, Semen Plantaginis has remarkable diuresis, can promote that respiratory mucus is secreted, dilution sputum, and has remarkable inhibitory action to various bacillus and staphylococcus.

Rhizoma Atractylodis: acrid in the mouth; Bitter; Warm in nature.Return spleen; Stomach; Liver Channel.Drying damp and strengthening spleen; Wind-damp dispelling; Improving eyesight.Cure mainly the spleen and stomach being stranded by dampness; Asthenia drowsiness; Born of the same parents' painful abdominal mass abdominal distention; Inappetence; Vomiting is had loose bowels; Phlegm retention; Damp-edema; Exterior syndrome folder is wet; Head heavy sensation of the body pain; Arthromyodynia warm nature; Podomere is ached serious symptom; Flaccidity folds in a garment; Nyctalopia." beautiful Chinese catalpa medicine solution " carries: " dry native diuretic, lets out drink expectorant, clots absorbing, dissipating depression of QI, goes Lou, changes addiction, and except disease, reason acid regurgitation removing the necrotic tissue, ward off mountains and rivers communicable subtropical diseases, the flaccidity returning muscles and bones is soft, excessive muddiness of urinating clearly." modern medicine study confirmation, volatile oil contained by Rhizoma Atractylodis has dispelling-wind invigorating stomach effect, and contained bitterness also has stomach invigorating, appetitive effect; have anti-enterospasm effect; have slight inhibitory action to heart, have slight dilating effect to blood vessel, and spinal reflex can also be impelled hyperfunction.

Herba Houttuyniae: acrid in the mouth; Cold in nature.Enter liver; Lung meridian.Heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Cure mainly lung abscess vomiting pus; Expectorant dyspnea of heat type is coughed; Larynx; Hematodiarrhoea; Carbuncle sore tumefacting virus; Pyretic stranguria." conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control upper respiratory tract infection, lung abscess, urinary tract inflammation and other position suppurative inflammation, venom." modern medicine study confirmation; Herba Houttuyniae can strengthen the phagocytic activity of WBC; improve immunity of organisms; all have inhibitory action to various microorganism, also has significant antagonism, antiviral, diuresis, analgesia, antitussive, hemostasis, suppression serous secretion in addition, promotes tissue regeneration, calmness, anticonvulsant action.

Herba Ephedrae: acrid in the mouth; Micro-hardship; Warm in nature.Return lung; Urinary bladder channel.Relieving the exterior syndrome by diaphoresis; Depressed lung-energy dispersing; Inducing diuresis to remove edema.Cure mainly chill exterior syndrome; Fever with aversion to cold; Lossless; Headache body pain; Heresy is stopped up in lung; Inhibited pulmonary QI; Cough and asthma; Edema caused by wind; Dysuria; Rheumatic arthralgia; Numbness of the skin and rubella pruritus; Carbuncle of yin nature sucutaneous nodule." herbal classic " carries: " main apoplexy, cold headache, pyrexial malaria.Deliver perspiration, uncharm steam, only cough with dyspnea, and except cold and heat, broken heavily fortified point gathers." modern medicine study shows; the ephedrine contained by Herba Ephedrae can play the adrenergic effect of class indirectly; strengthen myocardial contraction; coronary artery dilating, brain, muscle vascular; shrink the internal organs such as kidney, spleen and skin, mucosa blood vessel; raising blood pressure, loose bronchus and gastrointestinal smooth muscle, increase trigone of bladder flesh and sphincteral tension force, tired skeletal muscle tensity can be made significantly and enduringly to raise, also have sweating and heat resolving, antibacterial, antiviral, antiallergic, immunity, antitussive in addition, relieving asthma, eliminate the phlegm, diuresis.

Rhizoma Imperatae: sweet in the mouth; Cold in nature.Enter lung; Stomach; The heart; Urinary bladder channel.Cooling blood for hemostasis; Clearing away heat and promoting production of body fluid; Inducing diuresis for treating stranguria syndrome.Cure mainly heat in blood hemorrhage; Calentura excessive thirst; Gastric heat vomiting; Dyspnea and cough due to lung-heat; The puckery pain of dribbling urination; Edema; Jaundice." herbal classic " carries: " main impairment caused by overstrain weakness with emaciation, invigorating the spleen and replenishing QI, except blood stasis, blood close cold and heat, diuresis." modern medicine study shows; Rhizoma Imperatae has significant diuresis, obviously shortens the recalcification time of blood plasma, has obvious inhibitory action; contained Coixol has inhibitory action to the contraction of skeletal muscle and metabolism to Fu Shi and S. sonnei, also has the effects such as calmness, antipyretic-antalgic in addition.

Rhizoma Alismatis: sweet in the mouth; Light; Cold in nature.Return kidney; Urinary bladder channel.Promoting diuresis to eliminate damp pathogen; Expel the heat-evil treating stranguria.Cure mainly dysuria; The puckery pain of pyretic stranguria; Edema distension; Have loose bowels; Dizziness due to fluid-retention; Seminal emission." not Lu " carries: " tonifying deficiency five kinds of over strain, except the five internal organs feeling of fullness, plays cloudy gas, stopping leak essence, quenches one's thirst, drenches drop, cuts off the water by bladder, three Jiao." modern medicine study confirmation, Rhizoma Alismatis has reduction cholesterol and atherosclerosis effect, improves liver lipid metabolism, reduces blood glucose, blood pressure, affects function of immune system, reduces serum hemolysin.

Spica Prunellae: bitter in the mouth; Pungent; Cold in nature.Return liver; Gallbladder meridian.Liver heat removing and eyesight improving; Powder detoxifcation.Cure mainly corneal nebula photophobia; Ophthalmalgia; Have a headache dizzy; Tinnitus; Scrofula; Goiter; Acute mastitis; Mumps; Carbuncle furuncle and phyma poison; Acute, chronic hepatitis; Hypertension." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " liver-wind of dispelling, network of passing through.Control facial hemiparalysis, row irritability, opens stagnation of liver-QI, only bones and muscles pain, ophthal malgia, loose scrofula, whole body tuberculosis." modern medicine study confirmation, Spica Prunellae has significant blood pressure lowering and antibacterial action.

Herba Cirsii: sweet in the mouth; Micro-hardship; Cool in nature.Enter liver; Spleen channel.Cooling blood for hemostasis; Clearing heat for detumescence.Cure mainly hemoptysis; Spit blood; Epistaxis; Hematuria; Stranguria with blood; Have blood in stool; Dysentery; Metrorrhagia and metrostaxis; Traumatic hemorrhage; Swollen ulcer drug." classifying herbal " carries: " control stranguria with blood to swell and ache, traumatic injury, redly to collapse, leucorrhea, heat clearing away, hemostasis, blood pressure lowering, dissipating blood stasis for subsidence of swelling.Control various hemorrhage, hypertension, jaundice, hepatitis, pyelitis." modern medicine study confirmation, Herba Cirsii energy vasoconstrictive, increased platelets counts number, promotes platelet aggregation and increases thrombin activity, suppresses fibrinolysin, thus accelerates hemostasis.There is certain inhibitory action to diphtheria corynebacterium, streptococcus pneumoniae, Hemolytic streptococcus, staphylococcus aureus, bacillus pyocyaneus, Bacillus proteus, escherichia coli, Bacillus typhi etc., also have the effects such as blood fat reducing, function of gallbladder promoting, diuresis, heart tonifying, boosting in addition.

Cortex Mori: sweet in the mouth; Pungent; Cold in nature.Return lung; Spleen channel.Eliminating pathogen from the lung for relieving asthma; Inducing diuresis to remove edema.Cure mainly lung-heat and breathe heavily expectorant; Diseases caused by retention of fluid stops lung; Distension dyspnea with rapid respiration; Edema; Foot gas; Dysuria." detailed outline " carries: Sang Zipi, and being longer than Li little Shui, is actually rush down its son also, therefore has aqueous vapor and the lung-fire person of having a surplus to should it in lung.Ten doses of clouds, dryly dry, and the genus of Cortex Mori, Semen Phaseoli is.Song cures Qian Yi and controls lung qi intenseness of heat, and cough is then breathed heavily, swelling of the face fever of the body, Xiebai San.Mulberry from skin, call skin together and all can pathogenic fire purging go from urine, Radix Glycyrrhizae pathogenic fire purging and slow in, Semen oryzae sativae lung heat clearing and nourishing blood, this be the criterion of all sides of eliminating the pathogens from the lung also.Unit's doctor's Luo Tianyi says fire and correction gas its eliminating the pathogens from the lung second of the three ten-day periods of the hot season, rush down heresy thus correction also.Cortex Mori water extract is got or n-butanol extract 300-500mg/kg gavage or lumbar injection, all has diuresis.Urine volume and sodium, potassium ion and chloride output, all increase.Blood vessel is had to the effect of shrinking with expansion, have inhibitory action to staphylococcus aureus, Bacillus typhi, shigella flexneri.

Periostracum Cicadae: sweet in the mouth; Salty; Cool in nature.Enter lung; Liver Channel.Dispelling wind-heat; Rash sore-throat relieving; Removing nebula to improve visual acuity; Expelling wind and relieving convulsion.Cure mainly anemopyretic cold; Laryngopharynx swelling and pain; Cough hoarseness; Stupid rash is not saturating; Rubella pruritus; Cataract; Infantile convulsion is twitched; Tetanus." detailed outline " carries: " control phlegm-accumulating vertigo, skin wind heat, varioliform exanthema is had an itch, tetanus and treatment toxic swelling tumor, and adult's aphonia, children's's lockjaw sky hangs, frightened night cry of crying, swelling of the vulva." modern medicine study confirmation; Periostracum Cicadae has obvious convulsion, sedation, can block parasympathetic conduction on neck, is widely used in treatment tetanus, chronic Herba Urticae Cannabinae is examined, suppurative otitis media, vasodilation; also have cough-relieving to cough in addition, the particularly effect coughed of itching of the throat.

Herba Pyrolae: sweet in the mouth; Bitter; Warm in nature.Return liver; Kidney channel.The kidney invigorating bone strengthening; Expelling wind and removing dampness; Cough-relieving; Hemostasis.Cure mainly lumbago due to renal deficiency; Rheumatic arthralgia; Muscles and bones flaccidity is soft; New chronic cough is coughed; Spit blood; Epistaxis; Metrorrhagia; Traumatic hemorrhage.Modern medicine confirms, there is increase myocardial contraction, antiarrhythmic effect, there is good dilating effect to methylepinephrine vasoconstriction, have inhibitory action to staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, shigella flexneri, Bacillus typhi and bacillus pyocyaneus etc.

Fructus Forsythiae: bitter in the mouth; Cold nature.Enter lung; The heart; Gallbladder meridian.Heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds.Cure mainly anemopyretic cold; Epidemic febrile disease; Pyretic stranguria urine retention; Carbuncle; Toxic swelling; Scrofula; Goiter; Sore throat.Shennong's Herbal carries: " main cold and heat, scrofula, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat." clinic study shows; Fructus Forsythiae has broad-spectrum antibacterial action; have very strong inhibitory action to staphylococcus aureus, Hayes dysentery bacterium; have certain inhibitory action to other pathogenic bacterium, influenza virus, fungus; contained oleanolic acid has heart tonifying, diuresis and hypotensive activity; Citrin can reduce vascular permeability and fragility, prevents haemolysis, also has antiinflammatory in addition, town is told, anti-liver injury effect.

Poria: sweet in the mouth; Light; Property is put down.Enter liver; Stomach; Spleen channel.Removing damp-heat; Let out turbid removing toxic substances; Easing joint movement.Cure mainly prunus mume (sieb.) sieb.et zucc. poison; Stranguria with turbid discharge; Have loose bowels; Muscles and bones spasm and pain; Foot gas; Carbuncle; Skin ulcer tinea; Scrofula; Goiter and mercurialism." detailed outline " carries: " curing rheumatism, sharp joint, stopping leak rushes down for strengthening the spleen and stomach, bone and muscle strengthening.Control contracture osteodynia, malignant boil carbuncle, separate hydrargyrum powder, Vermilion poison." take orally and decoct soup; External is ground into powder and is dressed.

The present invention compared with prior art, has following beneficial effect:

The present invention selects medical material monarch, minister, a left side, makes all reasons all standby, the property of medicine is suitable mutually auxiliary mutually, for retention of damp-heat in the interior, water-damp not being transformed, kidney yin not road is suited the remedy to the case, and has effect of heat-clearing and toxic substances removing, YIN nourishing, heat clearing away, diuretic, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to acute pyelitis cure rate through clinical verification.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material composition of effective ingredient of the present invention and weight are:

Rhizoma Dioscoreae 70g Herba Leonuri 65g Radix Rehmanniae 60g Semen Plantaginis 60g

Rhizoma Atractylodis 55g Herba Houttuyniae 50g Herba Ephedrae 50g Rhizoma Imperatae 45g

Rhizoma Alismatis 45g Spica Prunellae 40g Herba Cirsii 40g Cortex Mori 30g

Periostracum Cicadae 30g Herba Pyrolae 30g Fructus Forsythiae 25g Poria 25g

The processing step of process for preparing medicine of the present invention is:

(1) Rhizoma Dioscoreae slow fire stir-fry is ground into powder to the micro-Huang of epidermis, cross 120 order fine powders, for subsequent use.

(2) Herba Ephedrae pulverizing is ground into powder, cross 120 order fine powders, for subsequent use.

(3) Rhizoma Alismatis is stir-fried with high heat and grind into powder after epidermis is golden yellow for several times, cross 120 order fine powders, for subsequent use.

(4) Herba Leonuri, Periostracum Cicadae, the Radix Rehmanniae, Semen Plantaginis, Rhizoma Atractylodis, Rhizoma Imperatae, Herba Houttuyniae are put into container, add the water of six times amount, soak after 3 ~ 5 hours, get immersion in remaining medicinal residues, add triplication again; Water, soaks after 1 ~ 2 hour, gets immersion; Merge twice gained immersion, under simmer down to 55 DEG C of environment, the thick paste of relative density 1.15 ~ 1.20, for subsequent use.

(5) Spica Prunellae, Fructus Forsythiae, Poria, Herba Pyrolae, Cortex Mori, Herba Cirsii are put into container, add the shao-hsing rice wine of qdx, boil rear continuation immersion and get immersion after 2 ~ 4 hours; In remaining medicinal residues, add the shao-hsing rice wine of doubling dose again, soak after 1 ~ 1.5 hour under room temperature, get immersion; Merge twice immersion, under simmer down to room temperature environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use.

(6) by the fine powder of step (1), step (2), step (3) gained, the thick paste obtained with step (4), step (5) mixes, add after refined honey stirs, be prepared as the tablet of 0.15g/ sheet.

Usage and dosage: every day 3 times, is grown up each 3, each 1 of child, and forward and backward 1 hour of meal is with warm water delivery service; The patient of serious symptom, every day 3 times, each 4, meal takes with ginger decoction for forward and backward 1 hour.

Embodiment 2

The raw material composition of effective ingredient of the present invention and weight are:

Rhizoma Dioscoreae 65g Herba Leonuri 62g Radix Rehmanniae 60g Semen Plantaginis 65g

Rhizoma Atractylodis 50g Herba Houttuyniae 50g Herba Ephedrae 48g Rhizoma Imperatae 45g

Rhizoma Alismatis 45g Spica Prunellae 40g Herba Cirsii 40g Cortex Mori 30g

Periostracum Cicadae 28g Herba Pyrolae 28g Fructus Forsythiae 23g Poria 22g

The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.

Embodiment 3

The raw material composition of effective ingredient of the present invention and weight are:

Rhizoma Dioscoreae 60g Herba Leonuri 60g Radix Rehmanniae 55g Semen Plantaginis 52g

Rhizoma Atractylodis 48g Herba Houttuyniae 48g Herba Ephedrae 46g Rhizoma Imperatae 42g

Rhizoma Alismatis 42g Spica Prunellae 38g Herba Cirsii 35g Cortex Mori 28g

Periostracum Cicadae 26g Herba Pyrolae 25g Fructus Forsythiae 22g Poria 20g

The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.

Clinical data:

1, case selection

Select the routine clinical observation of acute pyelitis patient 80 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random.Treatment group 40 example, wherein child 28 example, the age, adult 12 example, the age was at 27 ~ 55 years old at 3 ~ 8 years old.Matched group 40 example, child 25 example, the age, adult 15 example, the age was at 31 ~ 58 years old at 4 ~ 7 years old.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.

2, treatment group patient takes medicine of the present invention, treatment group every day 3 times, is grown up each 3, each 1 of child, serious symptom person, every day 3 times, each 4, within 7 days, is a course for the treatment of, recovers completely in 3 ~ 6 months.Matched group is according to the acute kidney diagnosed out, and give the blue or green enzyme element of intramuscular injection or other effective antibiotics respectively, seriously all quiet note furosemide is with stable, the quiet treatment means such as sodium nitroprusside, phentolamine, within 10 days, be a course for the treatment of, just fade away in 5 ~ 12 months, minority case is rehabilitation gradually after 1 ~ 2 year.

3, efficacy determination:

(1) fully recover: the symptoms such as edema, oliguria, hematuria, hypertension disappear entirely.

(2) take a turn for the better: serum urea nitrogen, creatinine clearance rate are stable, and routine urinalysis is at normal range value.

(3) invalid: symptom is with treating front no significant difference.

4, result:

Cure 32 examples in treatment group, take a turn for the better 8 examples, invalid 0 example, cure rate 86%, total effective rate 95%.

Cure 20 examples in matched group, take a turn for the better 5 examples, invalid 15 examples, cure rate 40%, total effective rate 57%

Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.

Group	n	Cure	Take a turn for the better	Invalid	Average cure time (d)	Cure rate %	Effective percentage %
								Matched group	40	20	5	15	10	40％	57％
Treatment group	40	32	8	0	7	86％	95％

The present invention has effect of heat-clearing and toxic substances removing, YIN nourishing, heat clearing away, diuretic, good absorbing effect, and the acute pyelitis caused many factors is evident in efficacy, has no side effect and clinical adverse, through clinical verification to acute pyelitis

Cure rate is higher.

Claims (4)

1. be used for the treatment of a Chinese prescription for acute pyelitis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 50 ~ 70 parts of Herba Leonuris 50 ~ 65 parts of Radix Rehmanniae 45 ~ 60 portions of Semen Plantaginiss 45 ~ 60 parts

Rhizoma Atractylodis 40 ~ 55 parts of Herba Houttuyniae 40 ~ 50 portions of Herba Ephedraes 40 ~ 50 parts of Rhizoma Imperataes 35 ~ 45 parts

Rhizoma Alismatis 35 ~ 45 parts of Spica Prunellaes 30 ~ 40 portions of Herba Cirsiis 25 ~ 40 parts of Cortex Mori 20 ~ 30 parts

10 ~ 25 parts, Periostracum Cicadae 20 ~ 30 portions of Herba Pyrolaes 15 ~ 30 parts of Fructus Forsythiaes 15 ~ 25 parts of Poria.

2. a kind of Chinese prescription being used for the treatment of acute pyelitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 55 ~ 65 parts of Herba Leonuris 55 ~ 65 parts of Radix Rehmanniae 50 ~ 60 portions of Semen Plantaginiss 50 ~ 60 parts

Rhizoma Atractylodis 45 ~ 50 parts of Herba Houttuyniae 45 ~ 50 portions of Herba Ephedraes 45 ~ 50 parts of Rhizoma Imperataes 40 ~ 45 parts

Rhizoma Alismatis 40 ~ 45 parts of Spica Prunellaes 35 ~ 40 portions of Herba Cirsiis 30 ~ 40 parts of Cortex Mori 25 ~ 30 parts

15 ~ 25 parts, Periostracum Cicadae 25 ~ 30 portions of Herba Pyrolaes 20 ~ 30 parts of Fructus Forsythiaes 20 ~ 25 parts of Poria.

3. a kind of Chinese prescription being used for the treatment of acute pyelitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:

Rhizoma Dioscoreae 60 parts of Herba Leonuris 60 parts of Radix Rehmanniae 55 portions of Semen Plantaginiss 55 parts

Rhizoma Atractylodis 48 parts of Herba Houttuyniae 48 portions of Herba Ephedraes 46 parts of Rhizoma Imperataes 42 parts

Rhizoma Alismatis 42 parts of Spica Prunellaes 48 portions of Herba Cirsiis 35 parts of Cortex Mori 28 parts

20 parts, Periostracum Cicadae 26 portions of Herba Pyrolaes 25 parts of Fructus Forsythiaes 22 parts of Poria.

4. be used for the treatment of a preparation method for the Chinese prescription of acute pyelitis, it is characterized in that: comprise following processing step:

(1) Rhizoma Dioscoreae slow fire stir-fry is ground into powder to the micro-Huang of epidermis, cross 120 order fine powders, for subsequent use.

(2) Herba Ephedrae pulverizing is ground into powder, cross 120 order fine powders, for subsequent use.

(3) Rhizoma Alismatis is stir-fried with high heat and grind into powder after epidermis is golden yellow for several times, cross 120 order fine powders, for subsequent use.

(4) Herba Leonuri, Periostracum Cicadae, the Radix Rehmanniae, Semen Plantaginis, Rhizoma Atractylodis, Rhizoma Imperatae, Herba Houttuyniae are put into container, add the water of six times amount, soak after 3 ~ 5 hours, get immersion in remaining medicinal residues, add triplication again; Water, soaks after 1 ~ 2 hour, gets immersion; Merge twice gained immersion, under simmer down to 55 DEG C of environment, the thick paste of relative density 1.15 ~ 1.20, for subsequent use.

(5) Spica Prunellae, Fructus Forsythiae, Poria, Herba Pyrolae, Cortex Mori, Herba Cirsii are put into container, add the shao-hsing rice wine of qdx, boil rear continuation immersion and get immersion after 2 ~ 4 hours; In remaining medicinal residues, add the shao-hsing rice wine of doubling dose again, soak after 1 ~ 1.5 hour under room temperature, get immersion; Merge twice immersion, under simmer down to room temperature environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use.

(6) by the fine powder of step (1), step (2), step (3) gained, the thick paste obtained with step (4), step (5) mixes, add after refined honey stirs, be prepared as the tablet of 0.15g/ sheet.