CN102652826A - Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine particle - Google Patents
Traditional Chinese medicine granule for treating infantile diarrhea and preparation method of traditional Chinese medicine particle Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine granule for treating infantile diarrhea and the preparation method of the traditional Chinese medicine particle. The traditional Chinese medicine granule is prepared by the following processes: carrying out water decoction, filtering, concentrating, drying, pelletizing, packing and the like by taking 25 medical materials as raw materials, such as clove, poria cocos, schisandra chinensis, flour-cooked kudzuvine root, fructus evodiae, salt plantain seed, scutellaria baicalensis, rhizoma alismatis, pericarpium arecae, fried Chinese date, fried hawthorn, salvia miltiorrhiza, coptis root, simmered costustoot, dark plum, houttuynia cordata, pericarpium citri reticulatae viride, astragalus mongholicus, baked ginger, bran-fried endothelium corneum gigeriae galli, bran-fried Chinese yam, cinnamon, carbonized sanguisorba root, roasted rhizoma atractylodis macrocephalae and flour-cooked medicine terminalia fruit. The traditional Chinese medicine granule has the effects of tonifying spleen and stopping diarrhea, helping digestion and eliminating indigestion, clearing heat and drying damp, is suitable for various infantile diarrheas including acute diarrhea, chronic diarrhea, infectious diarrhea and non-infectious diarrhea; and the traditional Chinese medicine granule has the characteristics of unique formula, prominent curative effect, less medicine use, quick effect, short treatment course, quick recovery, no toxic and side effects and the like, and is convenient to carry and take. After the traditional Chinese medicine granule for treating the infantile diarrhea is adopted to treat 263 patients, the total effective rate reaches more than 98%.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, be specifically related to a kind of Chinese medicinal granule of treating infantile diarrhea and preparation method thereof.
Background technology
Infantile diarrhea is one of UDC, is the modal digestive tract syndrome of China's infant, be by many cause of diseases, it is multifactor that what cause is one group of main clinical syndrome with diarrhoea.Age of onset is many below 3 years old, accounts for 50% with interior person in 1 years old.Every day is died from the diarrheal child up to 5,000,000-1,800 ten thousand in the whole world.In China, infantile diarrhea is the 2nd commonly encountered diseases, the frequently-occurring disease that is only second to respiratory tract infection.The traditional Chinese medical science claims that primary disease is " infantile diarrhea ", thinks not full maturity, vulnerable of children's's the spleen tending to insufficiency usually, digestive system development, therefore, improper feeding, unhygienic diet, stuffs oneself, is affected by the cold, infects or the like in the intestinal, all possibly cause infantile diarrhea.Because the cause of disease of infantile diarrhea is many-sided, the Therapeutic Principle of doctor trained in Western medicine be to digestive tract with suitable rest, the control intestinal is inside and outside to be infected and good nursing care, but therapeutic effect is unsatisfactory.The medicine and the Therapeutic Method that still lack at present effectively the infantile diarrhea that causes to a variety of causes.
Summary of the invention
It is a kind of evident in efficacy that the object of the invention is to provide, and can treat sick Chinese medicinal granule of all kinds of infantile diarrheas and preparation method thereof.
Technical solution of the present invention is:
A kind of Chinese medicinal granule of treating infantile diarrhea is characterized in that being prepared from by weight ratio following medical material: Flos Caryophylli 0.5-1 part, Poria 2-5 part, Fructus Schisandrae Chinensis 1-4 part, face roasted RADIX PUERARIAE 2-5 part, Fructus Evodiae 1-3 part, stir-baked SEMEN PLANTAGINIS with salt solution 1-3 part, Radix Scutellariae 1-3 part, Rhizoma Alismatis 2-4 part, Pericarpium Arecae 1-3 part, parching to brown Fructus Jujubae 2-6 part, Fructus Crataegi (parched to brown) 2-6 part, Radix Salviae Miltiorrhizae 2-3 part, Rhizoma Coptidis 1-3 part, Radix Aucklandiae (roasted) 1-2 part, Fructus Mume 1-3 part, Herba Houttuyniae 5-9 part, Pericarpium Citri Reticulatae Viride 1-1.5 part, Radix Astragali 2-9 part, Rhizoma Zingiberis Preparatum 1-3 part, parched with bran Endothelium Corneum Gigeriae Galli 1-3 part, Rhizoma Dioscoreae (parched with bran) 2-9 part, Cortex Cinnamomi 0.5-1 part, charred Radix Sanguisorbae 2-6 part, Rhizoma Atractylodis Macrocephalae (parched) 2-4 part, face Fructus Chebulae (roasted) 2-4 part.
The concocting method of said medical material is: the face roasted RADIX PUERARIAE: get clean Radix Puerariae with wetted surface group parcel, put in the parch container, simmer to little Jiao of dough cover, the Radix Puerariae decoction pieces is buff and is degree; Parching to brown Fructus Jujubae: remove in the nuclear Fructus Jujubae parch container, fry to surperficial burnt brown inner yellowish-brown; Rhizoma Dioscoreae (parched with bran): get pure Yam slice, fry to yellow according to an appendix II of Chinese Pharmacopoeia D parched with bran method; Parched with bran Endothelium Corneum Gigeriae Galli: get clean Endothelium Corneum Gigeriae Galli, fry to heaving according to an appendix II of Chinese Pharmacopoeia D parched with bran method; The face Fructus Chebulae (roasted): get clean Fructus Chebulae with wetted surface group parcel, put in the parch container, simmering to little Jiao of dough cover is to spend.
The method for preparing of the Chinese medicinal granule of described treatment infantile diarrhea is characterized in that the totally 25 flavor medical material decocte with water twice of the Flos Caryophylli of weighing by weight ratio, Poria, Fructus Schisandrae Chinensis, face roasted RADIX PUERARIAE, Fructus Evodiae, stir-baked SEMEN PLANTAGINIS with salt solution, Radix Scutellariae, Rhizoma Alismatis, Pericarpium Arecae, parching to brown Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Aucklandiae (roasted), Fructus Mume, Herba Houttuyniae, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Rhizoma Zingiberis Preparatum, parched with bran Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae (parched with bran), Cortex Cinnamomi, charred Radix Sanguisorbae, Rhizoma Atractylodis Macrocephalae (parched with bran), face Fructus Chebulae (roasted) are added water 6-12 doubly at every turn; The each decoction 0.5-2 hour merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into the thick paste that relative density is 1.25-1.30; Drying under reduced pressure adds an amount of cane sugar powder, granulates; Dry; Granulate divides packing, promptly gets.
Usage and dosage: boiled water is taken after mixing it with water.One-year-old with interior one time 2～5 gram, one-year-old to three years old one time 5～10 gram, four years old to 12 years old one time 10～15 gram, 2～3 times on the one.
Motherland's medical science thinks that infant shape in period gas does not fill, and internal organs are tender and lovely, the diseases caused by exogenous pathogenic factor cold-damp, and internal damage caused by infantile dyspepsia, eating and drinking without temperance, impairing the spleen and stomach makes and suffers from diarrhoea due to the weakness of the spleen and stomach.The spleen and stomach provide the material basis of the acquired, source of generating QI and blood, and main transporting and transforming nutrients from foodstuff is precise and tiny wet with water.Affection of cold wets, gets ill from overeating or be damp and hot, and spleen injury can not be transported the angry blood of water paddyization, can not transport the wet descending bladder of water again, causes Shui Gu and water and wets and walk intestinal, closes and for having loose bowels.Infantile diarrhea mainly is because weakness of spleen and stomach causes dysfunction of the spleen in transportation, and due to clear QI being mixed up with turbid QI, water are walked between intestinal, and spleen-asthenia with excessive damp be its pathology key, likes warm-dryness syndrome because of spleen and dislikes wet.Infantile diarrhea is in the traditional Chinese medical science or damp and hot, or summer-heat, or cold-damp, or gets ill from overeating.The present invention is the secret prescription handed down in the family from generation to generation of treatment infantile diarrhea, is made up of 25 flavor Chinese medicines, the infantile diarrhea effective percentage is reached more than 98%, and short treating period, instant effect, have no side effect.Rhizoma Dioscoreae (parched with bran) invigorating the spleen to arrest diarrhea in the side, Rhizoma Atractylodis Macrocephalae (parched), Poria spleen invigorating fortune wet, and Rhizoma Alismatis, stir-baked SEMEN PLANTAGINIS with salt solution promoting diuresis to eliminate damp pathogen antidiarrheal are monarch drug; Fructus Evodiae warming and recuperating the spleen and kidney, supporing yang antidiarrheal, Rhizoma Zingiberis Preparatum warming middle-JIAO to stop diarrhea, Flos Caryophylli warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG; The YANG invigorating of Cortex Cinnamomi warming middle-JIAO, dispersing cold for relieving pain, trimethyl gallic acid is held back astringent or styptic treatment for spontaneous sweating; Face Fructus Chebulae (roasted) relieving diarrhea with astringents, Radix Astragali replenishing QI to invigorate the spleen, parching to brown Fructus Jujubae spleen reinforcing nourishing the stomach antidiarrheal; Radix Aucklandiae (roasted), Pericarpium Citri Reticulatae Viride, Pericarpium Arecae, Fructus Crataegi (parched to brown) and parched with bran Endothelium Corneum Gigeriae Galli circulation of qi promoting removing dampness, dyspepsia and intestinal stasis relieving are ministerial drug; Face roasted RADIX PUERARIAE promoting the production of body fluid to quench thirst yang invigorating antidiarrheal, Radix Scutellariae, Rhizoma Coptidis, Herba Houttuyniae heat clearing and damp drying, treatment hematodiarrhoea dysentery, charred Radix Sanguisorbae, Fructus Mume eliminating pathogenic heat from blood to cure dysentery, the Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing is adjuvant drug; At the medicine coupling, play the merit of invigorating the spleen to arrest diarrhea, promoting digestion and removing stagnation, heat clearing and damp drying altogether, be applicable to all kinds of infantile diarrheas, comprise acute and chronic diarrhea, infection and noninfectious diarrhea.
Theory of Chinese medical science is analyzed:
Theory of Chinese medical science thinks that The spleen has the function to transport and transform nutrients, if being invaded by exogenous pathogen, improper diet or sickness influence all can cause spleen fortune not normal, indigestion, and defeatedization of becoming thoroughly decomposed is not normal and to send out be to suffer from diarrhoea.
Rhizoma Dioscoreae (parched with bran): get pure Yam slice, fry to yellow according to parched with bran method (an appendix II of Chinese Pharmacopoeia D).Nature and flavor are sweet, flat, return spleen, lung, kidney channel.The Rhizoma Dioscoreae (parched with bran) spleen reinforcing is good for the stomach, and is used for insufficiency of the spleen lack of appetite, the loose stool of having loose bowels.Compendium of Material Medica: " kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, the saliva that reduces phlegm, profit fur ".
Rhizoma Atractylodis Macrocephalae (parched): hardship, Gan Wen returns the taste warp, invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive." property of medicine opinion ": " the broken dyspepsia that disappears, appetizing ... let out under ending ... preventing or arresting vomiting is contrary, cold type of pain in the abdomen, it is more than to vomit and diarrhoea, and the insufficiency of stomach-QI cold-dysentery "; " medicine origin ": " the dry and middle QI invigorating of dehumidifying benefit, warming middle-JIAO removes the taste being attacked by dampness, removes gastric heat, and strong taste advance diet, stomach function regulating, born fluid.It has strong, diuresis modern pharmacological research.
Poria: sweet, light, flat, GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, the spleen invigorating mind calming." property of medicine opinion ": " appetizing, preventing or arresting vomiting is contrary "; " concise exposition on febrile disease ": " the slow spleen of infiltration "; " curing mainly secret formula " cloud: antidiarrheal.It has diuresis modern pharmacological research, and is antibiotic and fall the effect of gastric acid.
The face Fructus Chebulae (roasted): get clean Fructus Chebulae with wetted surface group parcel, put in the parch container, simmering to little Jiao of dough cover is to spend.Fructus Chebulae's picric acid, puckery flat, return lung, large intestine channel.Astringing intestine to stop diarrhea is astringed the lung, the pathogenic fire reducing sore-throat relieving." Japan hanako materia medica ": " antidiarrheal dysentery, cholera ... digesting and appetizing, hemorrhoidal hamorrhage rushes down blood "; The Fructus Chebulae can promote the be good for the stomach effect of solid intestinal of warming middle-JIAO, " explaining abstruseness of the canon of materia medica " after face is simmered: " simmer with then can the solid intestinal of warming the stomach ".It has antibiotic (dysentery bacterium) and cardiotonic modern pharmacological research.
The Radix Astragali: sweet, temperature.Return lung, spleen channel.Tonifying Qi and lifting yang is with controlling the deficiency of vital energy, lack of appetite, the just quiet card that waits.These article contain saccharide, choline, betanin, several aminoacid etc.Various bacteria there is antibacterial action.
Cortex Cinnamomi: hot, sweet, big heat.Return kidney, spleen, the heart, Liver Channel.Warming middle-JIAO YANG invigorating, cold relieving pain relieving are cold with controlling lower abdomen, and deficiency of spleen-YANG and kidneyYANG stomachache is had loose bowels.Cortex Cinnamomi mainly contains Oleum Cinnamomi.Gastrointestinal there is the abirritate effect, can strengthens digestive function, get rid of the digestive tract pneumatosis, alleviate gastrointestinal convulsion.The blood vessel dilating effect is arranged, strengthen blood circulation.Dysentery bacterium there is inhibitory action.
Flos Caryophylli: suffering, temperature.Return spleen, stomach, lung, kidney channel.Warming middle-JIAO to send down the adverse QI, pain relieving cure mainly institute's abdomen cold type of pain, and vomiting is had loose bowels.Containing volatile oil is Oleum Caryophylli.It leaches fluid power significantly increases gastric acid output and peptic activity of stomach.Bacillus pestis, vibrio cholera, anthrax bacillus, dysentery bacterium, escherichia coli there is inhibitory action.
Rhizoma Alismatis: sweet, cold.Return kidney, urinary bladder channel.Diuretic, eliminating dampness by diuresis expels the heat-evil.Be used for dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria.Compendium of Material Medica: " preventing or arresting vomiting is told, dysentery, colic, beriberi for eliminating dampness by diuresis heat, row phlegm retention ".
Stir-baked SEMEN PLANTAGINIS with salt solution: get clean Semen Plantaginis, process method (an appendix II of Chinese Pharmacopoeia D) according to saline and fry when playing cracker, spray saline, fry and do.Sweet, be slightly cold.Return liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, makes eye bright, and eliminates the phlegm.Be used for the edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.Compendium of Material Medica: " ending the heat-damp in summer dysentery "." Thunder God is concocted the property of medicine and is separated ": " the main drop difficulty in urination that drenches, penis swells and ache, and eczema is had loose bowels, and also leucorrhea is turbid, blood closes difficult labour ".
Fructus Evodiae: hot, bitter, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Be used for headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, the vomiting acid regurgitation is had loose bowels just before dawn.Shennong's Herbal: " main warming the middle warmer and descending qi, pain relieving, the cough with dyspnea cold and heat, the dehumidifying arthralgia due to stagnation of blood, by ailment said due to cold or exposure, loosing the interspaces of skin and muscles ".
Rhizoma Zingiberis Preparatum: get the Rhizoma Zingiberis Recens piece, put the urgent stir-fry of useing force in the pot and heave to foaming, crust is coke yellow, in be yellow, the spray little of clean water is taken out, and dries.Hot, hot.Return spleen, stomach, kidney, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, the cold extremities faint pulse, and phlegm retention is breathed with cough.Wang Hao Gu: "The gun is Wenpi dry stomach"; "Introduction to Medicine": "Bao Jiang, warm stomach, Pondicherry Kansui vent, diarrhea intestinal bleach, long malaria, cholera; confidants Leng Tong fullness, only epistaxis, Tuoxue, bloody diarrhea, bleeding. "
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea.Li Gao: " promoting the production of body fluid to quench thirst.Control dysentery, invigorating primordial QI is not enough, receives the gas of dissipation, platycoria ".
Parching to brown Fructus Jujubae: remove the nuclear Fructus Jujubae and put in the parch container, fry to surperficial burnt brown inner yellowish-brown.Sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, tranquilizing by nourishing the heart.Be used for diarrhea due to hypofunction of the spleen, cardiopalmus, insomnia, night sweat, thrombocytopenic purpura.Behind the Fructus Jujubae parching to brown, strengthened the effect of its invigorating the spleen to arrest diarrhea, and effective ingredient is fried easily, can be used for treating spleen-stomach deficiency-cold and have loose bowels.
Radix Aucklandiae (roasted): get undried Radix Aucklandiae sheet, in the iron wire plaque, use one deck toilet paper, one deck Radix Aucklandiae sheet at interval tiles several layers, puts in the other or drying chamber of stove fire, and baking simmers that contained volatile oil oozes to paper to the Radix Aucklandiae, takes out.The Radix Aucklandiae is hot, bitter, temperature.Return spleen, stomach, large intestine, three warmers, gallbladder meridian.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used to have loose bowels." Japan hanako materia medica ": control all gas of trusted subordinate, antidiarrheal, cholera, dysentery, antiabortive, strengthening the spleen to promote digestion.It is bad to treat win, bladder cold type of pain, vomiting and regurgitation.
Pericarpium Citri Reticulatae Viride: bitter, hot, temperature.Return liver, gallbladder, stomach warp.Soothing the liver dispelling the stagnated QI, removing food stagnancyization stagnates.Be used for distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Pericarpium Arecae: suffering, tepor.Return spleen, stomach, large intestine, small intestine meridian.Therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, line water detumescence.Be used for retention of damp leading to blockage of QI, gastral cavity abdominal distention is vexed, and it is not well to defecate, edema distension, beriberi edema, dysuria." book on Chinese herbal medicine is new again ": " dampness removing chases after wind for eliminating the pathogens from the lung, easing stomach-QI, wide intestinal detumescence, reason waist beriberi, treating malaria disease dysentery ".
Fructus Crataegi (parched to brown): get clean Fructus Crataegi, fry to surperficial burnt brown inner yellowish-brown according to frying method (an appendix II of Chinese Pharmacopoeia D).Sour, sweet, tepor.Return spleen, stomach, Liver Channel.Promoting digestion and invigorating the stomach, the circulation of qi promoting dissipating blood stasis.Be used for meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.Be used for meat stagnation, dysentery is not well.
Parched with bran Endothelium Corneum Gigeriae Galli: get clean Endothelium Corneum Gigeriae Galli, fry to heaving according to parched with bran method (an appendix II of Chinese Pharmacopoeia D).Sweet, flat.Return spleen, stomach, small intestinal, urinary bladder channel.Invigorating the stomach and promoting digestion, arresting seminal emission.Be used for food stagnation and do not disappear, vomiting dysentery, infantile malnutrition, the enuresis, seminal emission.
The face roasted RADIX PUERARIAE: clean Radix Puerariae is put in the parch container with wetted surface group parcel, simmers to little Jiao of dough cover, Radix Puerariae decoction pieces to be buff for being degree.Radix Puerariae is sweet, hot, cold.Return spleen, stomach warp.Expelling pathogenic factors from muscles for reducing heat promotes the production of body fluid, rash, yang invigorating antidiarrheal.Be used for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea is had loose bowels.Strengthened its yang invigorating antidiarrheal effect after simmering system." herbal classic is met former ": Radix Puerariae is frivolous, gives birth to yang invigorating then to promote the production of body fluid, and ripe usefulness is then inspired gastric qi, so control the insufficiency of stomach work yearningly.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma Coptidis: hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery etc.
Herba Houttuyniae: suffering is slightly cold.Return lung meridian.Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.Be used for the lung abscess vomiting pus, the expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Charred Radix Sanguisorbae: get pure land elm sheet, fry to surperficial coke black, inner sepia according to parch to black method (an appendix II of Chinese Pharmacopoeia D).Bitter, acid, puckery are slightly cold.Return liver, large intestine channel.Cooling blood for hemostasis, skin ulcer is held back in detoxifcation.Be used to have blood in stool hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus." Japan hanako materia medica ": " evacuation of pus, emesis blood, serious epistaxis, menstruation is more than, metrorrhagia, all blood disorders in antenatal back, dysentery with red and white feces and watery diarrhea, the dense only hemorrhoidal hamorrhage of frying in shallow oil ".
Fructus Mume: sour, puckery, flat.Return liver, spleen, lung, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.Be used for chronic cough of deficiency lung, the chronic dysentery laxation, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.Compendium of Material Medica: " astringing intestine to stop diarrhea of astringing the lung is controlled chronic cough, dysentery, and regurgitation is dysphagic, ascariasis of biliary tract vomiting and diarrhea, detumescence is gushed expectorant, parasite killing ".
Radix Salviae Miltiorrhizae: hardship is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, the amenorrhea dysmenorrhea, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris." herbal classic ": " main trusted subordinate's pathogen, borborygmus are faint as leaking water, and cold and heat gather; Broken disease is removed abdominal mass, ends stuffy sensation with restlessness, QI invigorating "." WU Pu Bencao ": control cardiac and abdominal pain.
The invention has the beneficial effects as follows: this Chinese medicinal granule effect is invigorating the spleen to arrest diarrhea, promoting digestion and removing stagnation, heat clearing and damp drying, is applicable to all kinds of infantile diarrheas, comprises acute and chronic diarrhea, infection and noninfectious diarrhea; Have characteristics such as prescription is unique, evident in efficacy, medication is few, rapid-action, short treating period, and carry, taking convenience, without any side effects and untoward reaction, suitable suitability for industrialized production; Adopt the present invention to treat totally 263 routine patients, total effective rate is more than 98%.
Compliance test result of the present invention:
Through Chinese medicine granules with method of the present invention preparation, at 2005 to 2012,263 routine patients are treated, with " the TCM Pediatrics disease is diagnosed criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's promulgation for including standard in; Male's 151 examples in the infant wherein, women's 112 examples, 2 months～6 years old age; Average 15 months, the course of disease 1～7 day, wherein mild dehydration person 48 examples; Moderate 7 examples, severe 2 examples do not have obvious dehydrator 206 examples.
1) diagnosis basis:
Times of defecation increases, and nearly more than 10 times, is faint yellow every day 3～5 times, and like egg soup sample, or color is brown and smelly, and a small amount of mucus can be arranged; Or with feeling sick, vomiting, stomachache, heating thirstyly waits disease; Excess in feeding is arranged, unhygienic diet or experience the medical history of seasonal pathogen; Weight person diarrhoea and vomiting be than severe patient, visible oliguria, fervescence, excessive thirst god withers, skin is shrivelled, sunken fontanel, the order pearl is sunk, crying without tears, the lip cherry is red, breathe profound, diseases such as abdominal distention; The stool microscopy can have Oil globule, a small amount of red white corpuscle; The inspection of stool pathogen can have growths such as Escherichia coli, or separates rotavirus etc.; Serious symptom diarrhoea has dehydration, acid base imbalance and electrolyte disturbance.
2) syndrome-classification
Diarrhea due to improper diet: stool acid is smelly, or as lose ovum, the abdominal part distension, halitosis is indigestion and loss of appetite, stomachache is cry and screamed before rushing down, and accompanies nausea and vomiting more.Thick fur is greasy, and rolling pulse is strong.Wind and cold rushes down: the stool color is light, has foam, does not have obvious foul smell, the stomachache borborygmus.Or companion's nasal obstruction, watery nasal discharge, fever of the body.White and greasy fur, rolling pulse is strong.Damp and hot rushing down: rush down like water sample, every day, for several times or tens of times color was brown and smelly, and mucus can be arranged, burning sensation of the anus, and oliguria with reddish urine, it is thirsty to generate heat.Red tongue, yellow and greasy fur, rapid pulse.Cold-damp diarrhea: stool several every day or ten several, color is lighter, can be with a small amount of mucus, no foul smell, lassitude, thirsty or thirst but no desire to drink, abdominal distention.White and greasy fur, soft pulse.Splenoasthenic diarrhea: incessant chronic diarrhea, or outbreak repeatedly, it is thin to defecate, or is water sample, has milk lobe or indigestion food debris, and Mental fatigue is indigestion and loss of appetite, lustreless complexion.Light red tongne, greasy and thin fur, weak pulse is unable.Deficiency of spleen-YANG and kidneyYANG rushes down: loose stool, aqueous-grainy diarrhea, emaciated physique, or asthenia facial edema, extremities being not warm.Pale tongue with white fur, thready pulse without strength.
3) efficacy evaluation
Cure: stool is shaped, and General Symptoms disappears.The stool microscopy is no abnormal, and etiological examination is negative.Take a turn for the better: times of defecation and moisture content reduce, and General Symptoms improves.The stool microscopy Oil globule or red, leukocyte is accidental.Do not heal: times of defecation and moisture content do not improve, or sx.
4) therapeutic effect:
The 263 routine patients that adopt the present invention to treat are carried out syndrome-classification by " TCM Pediatrics disease diagnosis criterion of therapeutical effect ", and wherein diarrhea due to improper diet patient totally 70 examples are cured 68 examples, 2 examples that take a turn for the better, and 0 example more, effective percentage is 100.0%; Wind and cold rushes down patient's totally 43 examples, cures 40 examples, 2 examples that take a turn for the better, and 1 example that do not heal, effective percentage is 97.7%; Damp and hot patient's totally 67 examples of rushing down are cured 65 examples, 1 example that takes a turn for the better, and 0 example that do not heal, effective percentage is 98.5%; The splenoasthenic diarrhea patient is totally 38 examples, cures 36 examples, 1 example that takes a turn for the better, and 1 example that do not heal, effective percentage is 97.4%; The cold-damp diarrhea patient is totally 21 examples, cures 19 examples, 1 example that takes a turn for the better, and 1 example that do not heal, effective percentage is 95.2%; Deficiency of spleen-YANG and kidneyYANG rushes down patient's totally 24 examples, cures 22 examples, 1 example that takes a turn for the better, and 1 example that do not heal, effective percentage is 95.8%; In sum, the patient adopts the present invention to treat totally 263 examples, cures 250 examples, 8 examples that take a turn for the better, and 4 examples that do not heal, total effective rate is 98.1%.
5) prominent example:
Case one: Li Te, the man at 10 monthly ages, lives in development zone, Juye County Pang Zhuan.Went to a doctor on October 8th, 2009, ill virus diarrhea, time egg soup sample loose stool surplus in the of days ten has symptoms such as heating, vomiting, abdominal distention, inappetence, through local county hospital three days invalid, take this granule and accused more in two days.
Case two: Wang Shuai, the man at 12 monthly ages, lives the cardinal principles of righteousness Zhen Wang village, Juye County.On JIUYUE 23rd, 2007 went to a doctor, ill virus diarrhea, and mother patient tells in generation; Symptom is to rush down the egg soup sample loose stool two days, and vomiting, diarrhoea, lethargy, appetite are poor, and symptom has no to improve through local county hospital; Take this granule after one day, diarrhoea obviously reduces, and continues clothes one day and heals.
Case three: Zhang Han, the woman at 13 monthly ages, lives Juye County's new city.Going to a doctor on November 6th, 2006, be noninfectious diarrhea, is green, milk lobe appearance feces, the time have watery stool to press from both sides a small amount of mucus, other integrative therapies February is surplus does not heal, and takes this granule and accuses more in three days.
The specific embodiment
Below in conjunction with embodiment the present invention is further specified, but be not limited thereto.
Embodiment 1:
Take by weighing Flos Caryophylli 10g, Poria 50g, Fructus Schisandrae Chinensis 40g, face roasted RADIX PUERARIAE 50g, Fructus Evodiae 30g, stir-baked SEMEN PLANTAGINIS with salt solution 30g, Radix Scutellariae 30g, Rhizoma Alismatis 40g, Pericarpium Arecae 30g, parching to brown Fructus Jujubae 60g, Fructus Crataegi (parched to brown) 60g, Radix Salviae Miltiorrhizae 30g, Rhizoma Coptidis 30g, Radix Aucklandiae (roasted) 20g, Fructus Mume 30g, Herba Houttuyniae 90g, Pericarpium Citri Reticulatae Viride 15g, Radix Astragali 90g, Rhizoma Zingiberis Preparatum 30g, parched with bran Endothelium Corneum Gigeriae Galli 30g, Rhizoma Dioscoreae (parched with bran) 90g, Cortex Cinnamomi 10g, charred Radix Sanguisorbae 60g, Rhizoma Atractylodis Macrocephalae (parched) 40g, face Fructus Chebulae (roasted) 40g totally 25 flavor medical materials respectively, decocte with water twice adds water 12000ml at every turn; The each decoction 0.5 hour merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into relative density be 1.25 thick paste of (60 ℃ of heat are surveyed), and the drying under reduced pressure powder 276g that gets dry extract adds the 24g cane sugar powder; Granulate; Drying, granulate gets granule 300g; Divide packing, promptly get.
Embodiment 2:
Take by weighing Flos Caryophylli 40g, Poria 160g, Fructus Schisandrae Chinensis 80g, face roasted RADIX PUERARIAE 160g, Fructus Evodiae 80g, stir-baked SEMEN PLANTAGINIS with salt solution 80g, Radix Scutellariae 80g, Rhizoma Alismatis 160g, Pericarpium Arecae 80g, parching to brown Fructus Jujubae 160g, Fructus Crataegi (parched to brown) 160g, Radix Salviae Miltiorrhizae 160g, Rhizoma Coptidis 80g, Radix Aucklandiae (roasted) 80g, Fructus Mume 80g, Herba Houttuyniae 400g, Pericarpium Citri Reticulatae Viride 80g, Radix Astragali 160g, Rhizoma Zingiberis Preparatum 80g, parched with bran Endothelium Corneum Gigeriae Galli 80g, Rhizoma Dioscoreae (parched with bran) 160g, Cortex Cinnamomi 40g, charred Radix Sanguisorbae 160g, Rhizoma Atractylodis Macrocephalae (parched) 160g, face Fructus Chebulae (roasted) 160g totally 25 flavor medical materials respectively, decocte with water twice adds water 18700ml at every turn; The each decoction 2 hours merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into relative density be 1.28 thick paste of (60 ℃ of heat are surveyed), and the drying under reduced pressure powder 935g that gets dry extract adds the 65g cane sugar powder; Granulate; Drying, granulate gets granule 1000g; Divide packing, promptly get.
Embodiment 3:
Take by weighing Flos Caryophylli 30g, Poria 150g, Fructus Schisandrae Chinensis 120g, face roasted RADIX PUERARIAE 150g, Fructus Evodiae 90g, stir-baked SEMEN PLANTAGINIS with salt solution 90g, Radix Scutellariae 90g, Rhizoma Alismatis 120g, Pericarpium Arecae 90g, parching to brown Fructus Jujubae 180g, Fructus Crataegi (parched to brown) 180g, Radix Salviae Miltiorrhizae 90g, Rhizoma Coptidis 90g, Radix Aucklandiae (roasted) 60g, Fructus Mume 90g, Herba Houttuyniae 270g, Pericarpium Citri Reticulatae Viride 45g, Radix Astragali 270g, Rhizoma Zingiberis Preparatum 90g, parched with bran Endothelium Corneum Gigeriae Galli 90g, Rhizoma Dioscoreae (parched with bran) 270g, Cortex Cinnamomi 30g, charred Radix Sanguisorbae 180g, Rhizoma Atractylodis Macrocephalae (parched) 120g, face Fructus Chebulae (roasted) 120g totally 25 flavor medical materials respectively, decocte with water twice adds water 37300ml at every turn; The each decoction 1 hour merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into relative density be 1.25 thick paste of (60 ℃ of heat are surveyed), and the drying under reduced pressure powder 920g that gets dry extract adds the 80g cane sugar powder; Granulate; Drying, granulate gets granule 1000g; Divide packing, promptly get.
Embodiment 4:
Take by weighing Flos Caryophylli 37.5g, Poria 175g, Fructus Schisandrae Chinensis 125g, face roasted RADIX PUERARIAE 175g, Fructus Evodiae 100g, stir-baked SEMEN PLANTAGINIS with salt solution 100g, Radix Scutellariae 100g, Rhizoma Alismatis 150g, Pericarpium Arecae 100g, parching to brown Fructus Jujubae 200g, Fructus Crataegi (parched to brown) 200g, Radix Salviae Miltiorrhizae 125g, Rhizoma Coptidis 100g, Radix Aucklandiae (roasted) 75g, Fructus Mume 100g, Herba Houttuyniae 350g, Pericarpium Citri Reticulatae Viride 62.5g, Radix Astragali 275g, Rhizoma Zingiberis Preparatum 100g, parched with bran Endothelium Corneum Gigeriae Galli 100g, Rhizoma Dioscoreae (parched with bran) 275g, Cortex Cinnamomi 37.5g, charred Radix Sanguisorbae 200g, Rhizoma Atractylodis Macrocephalae (parched) 150g, face Fructus Chebulae (roasted) 150g totally 25 flavor medical materials respectively, decocte with water twice adds water 27300ml at every turn; The each decoction 1.5 hours merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into relative density be 1.27 thick paste of (60 ℃ of heat are surveyed), and the drying under reduced pressure powder 952g that gets dry extract adds the 48g cane sugar powder; Granulate; Drying, granulate gets granule 1000g; Divide packing, promptly get.
Content disclosed according to the present invention, those skilled in the art can use the present invention to greatest extent.Therefore, above-mentioned preferred embodiment only illustrates, but not limits scope of the present invention by any way.
Claims (3)
1. a Chinese medicinal granule of treating infantile diarrhea is characterized in that being prepared from by weight ratio following medical material: Flos Caryophylli 0.5-1 part, Poria 2-5 part, Fructus Schisandrae Chinensis 1-4 part, face roasted RADIX PUERARIAE 2-5 part, Fructus Evodiae 1-3 part, stir-baked SEMEN PLANTAGINIS with salt solution 1-3 part, Radix Scutellariae 1-3 part, Rhizoma Alismatis 2-4 part, Pericarpium Arecae 1-3 part, parching to brown Fructus Jujubae 2-6 part, Fructus Crataegi (parched to brown) 2-6 part, Radix Salviae Miltiorrhizae 2-3 part, Rhizoma Coptidis 1-3 part, Radix Aucklandiae (roasted) 1-2 part, Fructus Mume 1-3 part, Herba Houttuyniae 5-9 part, Pericarpium Citri Reticulatae Viride 1-1.5 part, Radix Astragali 2-9 part, Rhizoma Zingiberis Preparatum 1-3 part, parched with bran Endothelium Corneum Gigeriae Galli 1-3 part, Rhizoma Dioscoreae (parched with bran) 2-9 part, Cortex Cinnamomi 0.5-1 part, charred Radix Sanguisorbae 2-6 part, Rhizoma Atractylodis Macrocephalae (parched) 2-4 part, face Fructus Chebulae (roasted) 2-4 part.
2. according to the Chinese medicinal granule of the treatment infantile diarrhea of claim 1, it is characterized in that the concocting method of said medical material is: the face roasted RADIX PUERARIAE: get clean Radix Puerariae with wetted surface group parcel, put in the parch container, simmer to little Jiao of dough cover, the Radix Puerariae decoction pieces is buff and is degree; Parching to brown Fructus Jujubae: remove in the nuclear Fructus Jujubae parch container, fry to surperficial burnt brown inner yellowish-brown; Rhizoma Dioscoreae (parched with bran): get pure Yam slice, fry to yellow according to an appendix II of Chinese Pharmacopoeia D parched with bran method; Parched with bran Endothelium Corneum Gigeriae Galli: get clean Endothelium Corneum Gigeriae Galli, fry to heaving according to an appendix II of Chinese Pharmacopoeia D parched with bran method; The face Fructus Chebulae (roasted): get clean Fructus Chebulae with wetted surface group parcel, put in the parch container, simmering to little Jiao of dough cover is to spend.
3. according to the method for preparing of the Chinese medicinal granule of the treatment infantile diarrhea of claim 1, it is characterized in that the totally 25 flavor medical material decocte with water twice of the Flos Caryophylli of weighing by weight ratio, Poria, Fructus Schisandrae Chinensis, face roasted RADIX PUERARIAE, Fructus Evodiae, stir-baked SEMEN PLANTAGINIS with salt solution, Radix Scutellariae, Rhizoma Alismatis, Pericarpium Arecae, parching to brown Fructus Jujubae, Fructus Crataegi (parched to brown), Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Radix Aucklandiae (roasted), Fructus Mume, Herba Houttuyniae, Pericarpium Citri Reticulatae Viride, the Radix Astragali, Rhizoma Zingiberis Preparatum, parched with bran Endothelium Corneum Gigeriae Galli, Rhizoma Dioscoreae (parched with bran), Cortex Cinnamomi, charred Radix Sanguisorbae, Rhizoma Atractylodis Macrocephalae (parched with bran), face Fructus Chebulae (roasted) are added water 6-12 doubly at every turn; The each decoction 0.5-2 hour merges the decoction medicinal liquid, filters; Filtrate decompression is concentrated into the thick paste that relative density is 1.25-1.30; Drying under reduced pressure adds an amount of cane sugar powder, granulates; Dry; Granulate divides packing, promptly gets.
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| CN102847124A (en) * | 2012-09-26 | 2013-01-02 | 张永红 | Medicine for treating infantile diarrhea and preparation method thereof |
| CN103285092A (en) * | 2013-07-08 | 2013-09-11 | 赵同合 | Patch for treating infantile diarrhea caused by damp and heat |
| CN103341148A (en) * | 2013-07-22 | 2013-10-09 | 黄晶晶 | Traditional Chinese medicine preparation for treating infantile diarrhea |
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| CN103285092A (en) * | 2013-07-08 | 2013-09-11 | 赵同合 | Patch for treating infantile diarrhea caused by damp and heat |
| CN103285092B (en) * | 2013-07-08 | 2015-04-08 | 赵同合 | Patch for treating infantile diarrhea caused by damp and heat |
| CN103341148B (en) * | 2013-07-22 | 2015-06-03 | 黄晶晶 | Traditional Chinese medicine preparation for treating infantile diarrhea |
| CN103341148A (en) * | 2013-07-22 | 2013-10-09 | 黄晶晶 | Traditional Chinese medicine preparation for treating infantile diarrhea |
| CN103623387A (en) * | 2013-12-20 | 2014-03-12 | 朱琳 | Traditional Chinese medicinal composition for treating diarrhea |
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