CN104474269A

CN104474269A - Natural medicine composition for treating diabetic nephropathy

Info

Publication number: CN104474269A
Application number: CN201410819849.1A
Authority: CN
Inventors: 聂淑惠; 杜秀萍; 居建华; 李继贤
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-12-23
Filing date: 2014-12-23
Publication date: 2015-04-01

Abstract

The inventiondiscloses a natural medicine composition for treating diabetic nephropathy. The natural medicine composition comprises the following twenty-six medicines: panaxjaponicus,citrus medica, seeds of Chinese coffeetrees, japanese ginseng roots, roots of saururuschinensis, roots of heracleumrepulafranch, polygonatumsibiricum, dictyophoraindusiata, fruits of ilex cornuta, strobilanthessarcorrhiza, lysimachia, zanthoxylumscandens, artocarpusstyracifoliuspierre, salvia miltiorrhiza, rhubarb, salvia prionitis,polyporusumbellatus,rhizomadioscoreaehypoglaucae, lobelia chinensis, semen plantaginis,eleocharisdulcis, callicarpa rubella, bitter herbs, roots of fagopyrumdibotrys, aletrispauciflora and liquorice.According to the theory of traditional Chinese medicine, diabetic nephropathy isalso called edema secondary to diabetes, stranguria and so on, the pathogenesis of diabetic nephropathy is blood stasis caused by deficiency, and blood stasis causes diabetic nephropathy. The natural medicine composition for treating diabetic nephropathy treats diabetic nephropathy by removing blood stasis, practicesthe therapeutic principle of nourishing yin to remove blood stasis, promoting blood circulation to remove blood stasis, tonifying qi to remove blood stasis, strengthening spleen to remove blood stasis, inducing diuresis to remove blood stasis and tonifying kidney to remove blood stasis, gives play to the advantages of comprehensive conditioning and whole treatment of the traditional Chinese medicine pharmacy, tonifies deficiency by nourishing yin, tonifying qi and reinforcing kidney, removes blood stasis by reducing phlegm, inducing diuresis,resolving dampness, activating blood and dredging collaterals andcontributes to blood stasis removal and deficiency tonifying, thereby achieving the aim of treating diabetic nephropathy.

Description

The natural drug composition for the treatment of diabetic nephropathy

Technical field

The present invention relates to the natural drug composition of a treatment diabetic nephropathy.

Background technology

Diabetic nephropathy is the Complicated with Severe card that diabetes de-velopment occurs to certain phase, major pathologic features is kidney enlargement, glomerular sclerosis, and clinical main manifestations comprises early stage glomerular filtration rate exception, albuminuria, edema, hypertension, renal hypofunction etc.The generation of diabetic nephropathy and progress concealment, the state of an illness is persistence, gradual development, finally causes end-stage renal failure.Therefore, early treatment intervenes, and delays the process of renal hypofunction, and effectively controlling diabetic nephropathy and worsen, is the key of clinical treatment diabetic nephropathy.

Diabetic nephropathy, according to Chinese medical theory discrimination, is diabetes secondary edema, stranguria etc., pathogenesis is the hyperamization stasis of blood because of void, causes a disease because of blood stasis, and namely so-called prolonged illness must be empty, prolonged illness must the stasis of blood, causes the stasis of blood by void, empty because of the stasis of blood, " disease enters deeply for a long time, and it is puckery that battalion defends trip, meridians lose to dredge event obstructed ", due to " quenching one's thirst " with the passing of time, body asthenia of both the spleen and kidney, deficiency of both QI and YIN, the transporting of essence of water and grain and body fluid is obstructed, raw in phlegm-damp, mechanism of qi blocks and lifting imbalance, causes phlegm-damp to hinder network, passages through which vital energy circulates is jammed, and deficiency of vital energy fortune blood is unable, thrombosis and the hyperamization stasis of blood, blood stasis one one-tenth, more very, damp is contain, blood stasis heat-transformation, and heat impairing vital QI is cloudy in mechanism of qi retardance, and water Tianjin can not normal spreading, run and stagnate, make blood stasis more very, " treatise on blood trouble " is said: " blood stasis sends out person thirsty, and with the life of body fluid, its root is born in kidney water, has blood stasis, then gas is that blood is cloudy, must not rise, and water Tianjin because of can not cloth in aqueous vapor, be with yearningly ", blood-stasis internal-depression, the stasis of blood, wet, heat, expectorant is tied mutually, with the passing of time strongly fragrant and removing toxic substances, and disappear bright body fluid, and poison is impairment of the kidney network, and " menstruation disorder is then water ", produces edema.Form diabetic nephropathy.

The present invention treats the natural drug composition of diabetic nephropathy, because of the empty and hyperamization stasis of blood according to diabetic nephropathy, the etiology and pathogenesis pathogenic because of blood stasis, treat from blood stasis, selects medicine reasonable formula, adopts yin nourishing blood stasis dispelling, blood circulation promoting and blood stasis dispelling, benefiting qi and removing blood stasis, Jianpi Huayu, diuretic blood stasis dispelling, Bushen Huayu to be the rule for the treatment of, play Drug therapy effect, yin nourishing, QI invigorating, spleen invigorating, reduce phlegm, the kidney invigorating, diuretic, eliminating dampness by diuresis, invigorate blood circulation, dredging collateral develops simultaneously, blood stasis dispelling tonify deficiency, reaches treatment diabetic nephropathy object.

Summary of the invention

The object of the invention is to provide a natural drug composition for the treatment of diabetic nephropathy.

In order to realize foregoing invention object, the present invention make the natural drug composition of this treatment diabetic nephropathy raw material composition and weight proportion be: Rhizoma Panacis Japonici 6 parts, Fructus Citri 4 parts, Semen Gymnocladi Chinensis 4 parts, Radix Panacis japonici 5 parts, Rhizoma Saururi 5 parts, Radix Heraclei Rapulae 5 parts, Rhizoma Polygonati 4 parts, Caulis Bambusae In Taeniam 4 parts, Fructus Ilicis Cornutae 5 parts, Strobilanthes sarcorrhizus Cling 6 parts, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 5 parts, Ramulus et Folium Zanthoxyli cuspidati 5 parts, storaxleaf artocarpus root 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 5 parts, Arisaema balansae Engl. grass 4 parts, Polyporus 4 parts, Rhizoma Dioscoreae Septemlobae 4 parts, Herba Lobeliae Chinensis 4 parts, Semen Plantaginis 4 parts, Corm Eleocharitis 6 parts, Folium Callicarpae Rubellae 5 parts, Herba Sonchi Oleracei 4 parts, Rhizoma Fagopyri Cymosi 4 parts, Herba Aletridis Khasianae 5 parts, 6 parts, Radix Glycyrrhizae.

The natural drug composition that the present invention treats diabetic nephropathy is made up of Rhizoma Panacis Japonici, Fructus Citri, Semen Gymnocladi Chinensis, Radix Panacis japonici, Rhizoma Saururi, Radix Heraclei Rapulae, Rhizoma Polygonati, Caulis Bambusae In Taeniam, Fructus Ilicis Cornutae, Strobilanthes sarcorrhizus Cling, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Ramulus et Folium Zanthoxyli cuspidati, storaxleaf artocarpus root, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Arisaema balansae Engl. grass, Polyporus, Rhizoma Dioscoreae Septemlobae, Herba Lobeliae Chinensis, Semen Plantaginis, Corm Eleocharitis, Folium Callicarpae Rubellae, Herba Sonchi Oleracei, Rhizoma Fagopyri Cymosi, Herba Aletridis Khasianae, Radix Glycyrrhizae 20 six medicaments, wherein:

Rhizoma Panacis Japonici is the rhizome of Araliaceae Rhizoma Panacis Japonici.Sweet in the mouth, micro-hardship, warm in nature.Return liver, spleen, lung meridian.Function is eliminated the phlegm dissipating blood stasis, spleen invigorating, detumescence, pain relieving, strengthening by means of tonics.

Fructus Citri is the dry mature fruit of rutaceae citron or fragrant circle.Acrid in the mouth, hardship, acid, warm in nature.Return liver, spleen, lung meridian.Function expectorant Shu Yu, the liver soothing and the spleen invigorating, alleviating distention in middle-JIAO reduces phlegm, regulating QI and lowering the adverseness.

Semen Gymnocladi Chinensis is the seed of leguminous plant Fructus Gymnocladi Chinensis.Sweet in the mouth, warm in nature.Function is eliminated the phlegm, relieving constipation, clearing away phlegm scale removal, and pertinacious phlegm of dispelling blocks.

Radix Panacis japonici is the fleshy tap root of Araliaceae panax japonicus c.a.mey.var.major (burk.) c.y.wu et k.m.feng.Sweet in the mouth, property is put down.Enter lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, YIN nourishing spleen invigorating.

Rhizoma Saururi is the rhizome of Saururaceae plant Rhizoma Saururi (Herba Saururi).Sweet in the mouth, pungent, cold in nature.Return spleen, large intestine, urinary bladder channel.Function air making-up and spleen enlivening, diuretic dehumidifies, inducing diuresis to remove edema, heat-clearing and toxic substances removing, fresh breeze damp-heat arthralgia.

Radix Heraclei Rapulae is the root of samphire Heracleum rapula.Acrid in the mouth, hardship, warm in nature.Return spleen, lung meridian.Function spleen invigorating dissipating blood stasis, expelling wind and removing dampness.

Rhizoma Polygonati is the rhizome of liliaceous plant Rhizoma Polygonati, Polygonatum cyrtonema Hua and P. kingianum.Sweet in the mouth, property is put down.Return spleen, lung, kidney channel.Function boosting qi and nourishing yin, invigorating the spleen and benefiting QI, yin nourishing nourishing kidney.

Caulis Bambusae In Taeniam is the sporophore of Phallaceae fungus Caulis Bambusae In Taeniam, short-skirted veiled lady.Sweet in the mouth, micro-hardship, cool in nature.Enter spleen, kidney channel.Function boosting qi and nourishing yin, spleen invigorating yin nourishing, clearing away heat-damp and promoting diuresis.

Fructus Ilicis Cornutae is the fruit of holly plant Ilex cornuta Lindl..Bitter in the mouth, puckery, slightly warm in nature.Return liver, kidney channel.Function invigorating the liver and kidney, strong muscle is active, and YIN nourishing is empty, interior-heat of dispelling, the astringent or styptic treatment for spontaneous sweating part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.

Strobilanthes sarcorrhizus Cling is root or the herb of acanthaceous plant Strobilanthes sarcorrhizus Cling.Sweet in the mouth, micro-hardship, cool in nature.Return kidney, stomach warp.Function tonifying kidney and nourishing yin, heat-clearing and toxic substances removing.

Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) is the herb of Ofthe Primulaceae Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis).Acrid in the mouth, micro-puckery, property is put down.Return liver, spleen channel.Function promoting blood circulation to remove blood stasis, promoting blood flow to regulate menstruation, clearing away heat-damp and promoting diuresis.

Ramulus et Folium Zanthoxyli cuspidati is stem and leaf or the root of rutaceae Ramulus et Folium Zanthoxyli cuspidati.Acrid in the mouth, warm in nature.Return Liver Channel.Function is invigorated blood circulation, dissipating blood stasis, resolving depression.

Storaxleaf artocarpus root is the root of moraceae plants storaxleaf artocarpus root.Sweet in the mouth, warm in nature.Function dissipating blood stasis, dispel the wind, removing dampness, promoting blood circulation to remove obstruction in the collateral.

Radix Salviae Miltiorrhizae is the root of labiate Radix Salviae Miltiorrhizae.Bitter in the mouth, cold nature.GUIXIN, Liver Channel.Function blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow, nourishing blood to tranquillize the mind, removing heat from blood eliminating carbuncle.

Radix Et Rhizoma Rhei is the dry root and rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Bitter in the mouth, cold in nature.Function clots absorbing blood, purge heat poison, and removing mass is stagnant, eliminating blood stasis and inducing menstruation.

Arisaema balansae Engl. grass is labiate Huangpu Salvia japonica Thunb. whole herb with root.Mildly bitter flavor, cool in nature.Return spleen, lung meridian.Function dampness removing, heat clearing away, dispelling wind.

Polyporus is the dry sclerotia of Polyporaceae plant Polyporus.Sweet in the mouth, light, property is put down.Enter spleen, kidney, urinary bladder channel.Function eliminating dampness by diuresis gas, dredging water passages, diuresis eliminating dampness by diuresis.

Rhizoma Dioscoreae Septemlobae is the rhizome of Dioscoreaceae Plant Powder back of the body Rhizoma Dioscoreae.Bitter in the mouth, property is put down.Return liver, stomach, urinary bladder channel.Function is oozed spleen and is wet, and dampness removing goes turbid, and dispel the wind blood stasis dispelling, and blood vessels.

Herba Lobeliae Chinensis is the whole herb with root of Campanulaceae Herba Lobeliae Chinensis.Sweet in the mouth, property is put down.GUIXIN, lung, small intestine meridian.Function heat-clearing and toxic substances removing, inducing diuresis to remove edema.

Semen Plantaginis is the dry mature seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.Sweet in the mouth, cold nature.Return liver, kidney, lung, small intestine meridian.Function clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, except arthralgia chiefly caused by damp pathogen, eliminates the phlegm.

Corm Eleocharitis is the bulb of sedge Corm Eleocharitis.Sweet in the mouth, cold in nature.Attach to the lung and stomach meridians.Function clearing away heat and promoting production of body fluid, spleen invigorating, removing mass is stagnant, and eliminate the phlegm removing food stagnancy.

Folium Callicarpae Rubellae is leaf and the twig of Verbenaceae Folium Callicarpae Rubellae.Mildly bitter flavor, property is put down.Return lung, kidney, urinary bladder channel.Function cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling.

Herba Sonchi Oleracei is the herb of feverfew Herba Sonchi Oleracei.Bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, large intestine channel.Function is dispelled the five internal organs pathogen, heat-clearing and toxic substances removing, removing heat from blood.

Rhizoma Fagopyri Cymosi is the root and rhizome of polygonaceae plant sky Semen Fagopyri Esculenti.Sour in the mouth is bitter, cold in nature.Function heat-clearing and toxic substances removing, expelling wind and removing dampness.

Herba Aletridis Khasianae is the herb of liliaceous plant Honoka alertris spicata.Acrid in the mouth, micro-hardship, warm in nature.Return lung, Liver Channel.Function diuretic, YIN nourishing, tonify deficiency arresting sweating.

Radix Glycyrrhizae is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..Sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.

Diabetic nephropathy belongs to traditional Chinese medical science diabetes secondary edema, the categories such as stranguria, pathogenesis is the hyperamization stasis of blood because of void, causes a disease because of blood stasis, and namely so-called prolonged illness must be empty, prolonged illness must the stasis of blood, causes the stasis of blood by void, empty because of the stasis of blood, " disease enters deeply for a long time, and it is puckery that battalion defends trip, meridians lose to dredge event obstructed ", due to " quenching one's thirst " with the passing of time, body asthenia of both the spleen and kidney, deficiency of both QI and YIN, the transporting of essence of water and grain and body fluid is obstructed, raw in phlegm-damp, mechanism of qi blocks and lifting imbalance, causes phlegm-damp to hinder network, passages through which vital energy circulates is jammed, and deficiency of vital energy fortune blood is unable, thrombosis and the hyperamization stasis of blood, blood stasis one one-tenth, more very, damp is contain, blood stasis heat-transformation, and heat impairing vital QI is cloudy in mechanism of qi retardance, and water Tianjin can not normal spreading, run and stagnate, make blood stasis more very, " treatise on blood trouble " is said: " blood stasis sends out person thirsty, and with the life of body fluid, its root is born in kidney water, has blood stasis, then gas is that blood is cloudy, must not rise, and water Tianjin because of can not cloth in aqueous vapor, be with yearningly ", blood-stasis internal-depression, the stasis of blood, wet, heat, expectorant is tied mutually, with the passing of time strongly fragrant and removing toxic substances, and disappear bright body fluid, and poison is impairment of the kidney network, and " menstruation disorder is then water ", produces edema.Form diabetic nephropathy.

The present invention treats the natural drug composition of diabetic nephropathy, treat from blood stasis, declines and unboiled water damp-phlegm drink for diabetic nephropathy deficiency of spleen-QI; Deficiency of both QI and YIN and raw stagnant heat resistance network; Stagnation of QI and blood, more increase scorching impairment of body fluid; Blood-stasis internal-depression, the stasis of blood, wet, heat, expectorant are tied mutually, with the passing of time strongly fragrant and removing toxic substances, and disappear bright body fluid, and the poison network that is impairment of the kidney forms nephropathy, and because of the empty and hyperamization stasis of blood, the etiology and pathogenesis pathogenic because of blood stasis, selects drug regimen, tonify deficiency blood stasis dispelling, plays Drug therapy effect.

In the natural drug composition for the treatment of diabetic nephropathy provided by the invention, the taste medicines such as Rhizoma Panacis Japonici, Fructus Citri, Semen Gymnocladi Chinensis, reduce phlegm, eliminating phlegm, pertinacious phlegm of dispelling, invigorating the spleen for dissipating phlegm, gather altogether eleminating phlegm and freeing channels, by the stagnant effect of expectorant sending down the abnormal ascending QI, blood stasis dispelling.

Deficiency-weakness of spleen-QI, the biochemical weary source of QI and blood, promotes QI and blood unable, stasis becomes the stasis of blood, i.e. " vigour is both empty, can not reach in blood vessel; blood vessel depletion of QI; must stop and the stasis of blood ", the taste medicine such as Radix Panacis japonici, Rhizoma Saururi, Radix Heraclei Rapulae, Rhizoma Polygonati, Caulis Bambusae In Taeniam, invigorating the spleen and replenishing QI, YIN nourishing spleen invigorating, spleen invigorating dissipating blood stasis, boosting qi and nourishing yin, spleen invigorating yin nourishing, go asthenic fire, yin nourishing YANG invigorating, has the merit of diuretic dehumidifying, expelling wind and removing dampness, heat clearing away poison concurrently, reaches the effect of removing dampness of invigorating blood circulation, invigorating the spleen and benefiting QI, reinforcing spleen and kidney, benefiting qi and removing blood stasis, Jianpi Huayu.

The taste medicines such as Fructus Ilicis Cornutae, Strobilanthes sarcorrhizus Cling, Rhizoma Polygonati, invigorating the liver and kidney, YIN nourishing void, interior-heat of dispelling, nourishing YIN and invigorating YANG, reinforcing YIN-essence benefit essence, promoting blood circulation to remove blood stasis, admittedly hold back essence and blood, has the effect of the kidney warming tonifying liver, Bushen Huayu.

The taste medicines such as Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Ramulus et Folium Zanthoxyli cuspidati, storaxleaf artocarpus root, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, promoting blood circulation to remove blood stasis, promoting blood flow to regulate menstruation, promoting blood circulation to remove obstruction in the collateral, eliminating blood stasis and inducing menstruation, hold concurrently with removing heat from blood and promoting blood circulation, clearing away heat-damp and promoting diuresis, the most deliciously share removing blood stasis blood and invigorate blood circulation, blood stasis is gone, and healthy energy is multiple, has eliminating blood stasis and inducing menstruation, blood circulation promoting and blood stasis dispelling, heat clearing and blood cooling, regulating menstruation imitates along feeling pulse.

The taste medicines such as Polyporus, Arisaema balansae Engl. grass, Rhizoma Dioscoreae Septemlobae, Herba Lobeliae Chinensis, Semen Plantaginis, eliminating dampness by diuresis gas, dredging water passages, dampness removing goes turbid, treating stranguria dehumidifying, removes the long-pending wet of the evil water of kidney, clear spleen, draw blood stasis, pyretic toxicity, phlegm-damp are descending, go out from urine, normal urination is then wet to be gone, wet and go, numbness is removed, and falls the asthenic fire of the deficiency of YIN, to rush down for mending, rush down kidney and the kidney invigorating, have concurrently eliminate the phlegm, dispel the wind, blood stasis dispelling, and the effect of blood vessels, the most deliciously to share, the favourable aquation stasis of blood, strengthening spleen, tonifying kidney, effect by expectorant sending down the abnormal ascending QI, damp eliminating eliminating impediment.

The taste medicines such as Corm Eleocharitis, Folium Callicarpae Rubellae, Herba Sonchi Oleracei, Rhizoma Fagopyri Cymosi, Herba Aletridis Khasianae, Yin-nourishing and body fluid promoting, clearing away heat and promoting diuresis, promoting blood circulation and cooling blood, spleen invigorating removing mass, eliminate the phlegm removing food stagnancy, and heat clearing away poison, effect that is turbid, cooling blood and removing stasis is gone in a yin nourishing blood stasis dispelling, clearing away heat and promoting production of body fluid, blood stasis dispelling.

Radix Glycyrrhizae invigorating the spleen and replenishing QI, the weakness with emaciation of strengthening the spleen and stomach, solid middle gas, association's negative and positive and uncomfortable battalion defend, current 12 warps, " walk that the person of altering obtains and hold back its cutting edge of a knife or a sword less, that the person of capturing obtains and do not hinder in high ", " enter gas with gas medicine; enter blood with blood medicine; without toward can not ", " all with the pure cold medicine of pure heat, must with Radix Glycyrrhizae with its gesture slow; the medicine that cold and heat are assorted mutually; must with Radix Glycyrrhizae with its property ", or assistant or make, the comprehensive onset of coordinating the actions of various ingredients in a prescription.

The present invention treats the natural drug composition of diabetic nephropathy, reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease, full side all medicine associatings mutual aid, yin nourishing blood stasis dispelling, blood circulation promoting and blood stasis dispelling, benefiting qi and removing blood stasis, Jianpi Huayu, diuretic blood stasis dispelling, Bushen Huayu, so-called " kind YANG invigorating person, must in treating YANG within YIN, then positive cloudy helping and biochemical infinite, kind nourishing YIN person, must in treating YIN within YANG, then YIN matched with sufficient YANG making living things fully vivid ", all medicines 5 are worked in coordination with mutually, tonifying for deficiency syndrome, reducing for the excess syndrome, cold Wen Bingji, reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease, blood stasis dispelling is not just being hindered, with yin nourishing, QI invigorating, spleen invigorating, the kidney invigorating and tonify deficiency, to reduce phlegm, diuretic, eliminating dampness by diuresis, invigorate blood circulation, dredging collateral and blood stasis dispelling, play blood stasis dispelling altogether, the merit of tonify deficiency.Reach treatment diabetic nephropathy object.

The present invention treats the natural drug composition of diabetic nephropathy, can be prepared into the multiple oral formulations such as pulvis, pill, capsule, tablet and use.

The present invention treats the natural drug composition of diabetic nephropathy, embodiment is prepared into watered pill dosage form and uses, by the Rhizoma Panacis Japonici in formula, Fructus Citri, Semen Gymnocladi Chinensis, Radix Panacis japonici, Rhizoma Saururi, Radix Heraclei Rapulae, Rhizoma Polygonati, Caulis Bambusae In Taeniam, Fructus Ilicis Cornutae, Strobilanthes sarcorrhizus Cling, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Ramulus et Folium Zanthoxyli cuspidati, storaxleaf artocarpus root, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Arisaema balansae Engl. grass, Polyporus, Rhizoma Dioscoreae Septemlobae, Herba Lobeliae Chinensis, Semen Plantaginis, Corm Eleocharitis, Folium Callicarpae Rubellae, Herba Sonchi Oleracei, Rhizoma Fagopyri Cymosi, Herba Aletridis Khasianae, the cleaning of Radix Glycyrrhizae 20 Six-element medical material, dry, fine powder is made in pulverizing, mix homogeneously, cross medicine sieve, with water pill, make watered pill.

Invention embodiment

The present invention treats the natural drug composition of diabetic nephropathy, prepares medicine by following consumption:

Rhizoma Panacis Japonici 6 kilograms, Fructus Citri 4 kilograms, Semen Gymnocladi Chinensis 4 kilograms, Radix Panacis japonici 5 kilograms, Rhizoma Saururi 5 kilograms, Radix Heraclei Rapulae 5 kilograms, Rhizoma Polygonati 4 kilograms, Caulis Bambusae In Taeniam 4 kilograms, Fructus Ilicis Cornutae 5 kilograms, Strobilanthes sarcorrhizus Cling 6 kilograms, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 5 kilograms, Ramulus et Folium Zanthoxyli cuspidati 5 kilograms, storaxleaf artocarpus root 5 kilograms, Radix Salviae Miltiorrhizae 5 kilograms, Radix Et Rhizoma Rhei 5 kilograms, Arisaema balansae Engl. grass 4 kilograms, Polyporus 4 kilograms, Rhizoma Dioscoreae Septemlobae 4 kilograms, Herba Lobeliae Chinensis 4 kilograms, Semen Plantaginis 4 kilograms, Corm Eleocharitis 6 kilograms, Folium Callicarpae Rubellae 5 kilograms, Herba Sonchi Oleracei 4 kilograms, Rhizoma Fagopyri Cymosi 4 kilograms, Herba Aletridis Khasianae 5 kilograms, 6 kilograms, Radix Glycyrrhizae.

By the Rhizoma Panacis Japonici in formula, Fructus Citri, Semen Gymnocladi Chinensis, Radix Panacis japonici, Rhizoma Saururi, Radix Heraclei Rapulae, Rhizoma Polygonati, Caulis Bambusae In Taeniam, Fructus Ilicis Cornutae, Strobilanthes sarcorrhizus Cling, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Ramulus et Folium Zanthoxyli cuspidati, storaxleaf artocarpus root, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, Arisaema balansae Engl. grass, Polyporus, Rhizoma Dioscoreae Septemlobae, Herba Lobeliae Chinensis, Semen Plantaginis, Corm Eleocharitis, Folium Callicarpae Rubellae, Herba Sonchi Oleracei, Rhizoma Fagopyri Cymosi, Herba Aletridis Khasianae, the cleaning of Radix Glycyrrhizae 20 Six-element medical material, dry, fine powder is made in pulverizing, mix homogeneously, cross medicine sieve, with water pill, make watered pill.

The curative effect of the natural drug composition for the treatment of diabetic nephropathy of the present invention is illustrated below by way of clinical treatment observation example.

One, diabetic nephropathy patient data

Patient 59 example, man 31 example, female 28 example; At 39 ~ 63 years old age, average 52 years old, all meet diabetic nephropathy diagnostic criteria, and get rid of other nephropathys.

Two, clinical treatment

(1) efficacy assessment standard

Curative effect is judged by grade III Standard.Obvious effective rate+effective percentage sum is total effective rate.

Effective: patient clinical transference cure, urine protein quantitation, qualitative feminine gender.

Effective: patient clinical symptom takes a turn for the better, urine protein quantitation declines more than 40% before comparatively treating.

Invalid: patient clinical symptom is without improvement or improve not obvious, urine protein quantitation is comparatively treated and is front lowerly reduced to 40%.

(2) therapeutic scheme

It is oral that patient gives watered pill prepared by natural drug composition embodiment that the present invention treats diabetic nephropathy, each 9g, every day 3 times, warm water delivery service.Within 30 days, be 1 course for the treatment of, treat 2 the course for the treatment of judged result.

Treatments period, patient uses insulin to control blood glucose value to normal range, uses medicine, other hypoglycemic medicines of other treatment diabetic nephropathy time different.

Three, therapeutic outcome

All patients completed treatment.After treating 2 courses for the treatment of, 59 routine diabetic nephropathy patient, effective 17 examples, effective 32 examples, invalid 10 examples, treatment total effective rate 83.1%.

Use the present invention to treat the natural drug composition treatments period of diabetic nephropathy, do not observe Patient drug's untoward reaction.

The natural drug composition prescription that the present invention treats diabetic nephropathy is rigorous, all medicines 5 are worked in coordination with mutually, cold Wen Bingji, reinforcement and elimination in combination, treating both the principal and secondary aspects of a disease, improves diabetes mellitus's nephropathy symptom, suppress the progress of renal hypofunction, treatment efficacy on diabetic nephropathy is satisfied, drug use safety, has higher popularizing value and promotes space.

Claims

1. the natural drug composition of a treatment diabetic nephropathy, the medicine composition and the weight proportion thereof that it is characterized in that making this natural drug composition are: Rhizoma Panacis Japonici 6 parts, Fructus Citri 4 parts, Semen Gymnocladi Chinensis 4 parts, Radix Panacis japonici 5 parts, Rhizoma Saururi 5 parts, Radix Heraclei Rapulae 5 parts, Rhizoma Polygonati 4 parts, Caulis Bambusae In Taeniam 4 parts, Fructus Ilicis Cornutae 5 parts, Strobilanthes sarcorrhizus Cling 6 parts, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 5 parts, Ramulus et Folium Zanthoxyli cuspidati 5 parts, storaxleaf artocarpus root 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 5 parts, Arisaema balansae Engl. grass 4 parts, Polyporus 4 parts, Rhizoma Dioscoreae Septemlobae 4 parts, Herba Lobeliae Chinensis 4 parts, Semen Plantaginis 4 parts, Corm Eleocharitis 6 parts, Folium Callicarpae Rubellae 5 parts, Herba Sonchi Oleracei 4 parts, Rhizoma Fagopyri Cymosi 4 parts, Herba Aletridis Khasianae 5 parts, 6 parts, Radix Glycyrrhizae.

2. the application of natural drug composition in the oral drug preparation for the preparation for the treatment of diabetic nephropathy for the treatment of diabetic nephropathy according to claim 1.