CL2021002918A1 - Composiciones y métodos de oximetazolina para el tratamiento de trastornos oculares - Google Patents
Composiciones y métodos de oximetazolina para el tratamiento de trastornos ocularesInfo
- Publication number
- CL2021002918A1 CL2021002918A1 CL2021002918A CL2021002918A CL2021002918A1 CL 2021002918 A1 CL2021002918 A1 CL 2021002918A1 CL 2021002918 A CL2021002918 A CL 2021002918A CL 2021002918 A CL2021002918 A CL 2021002918A CL 2021002918 A1 CL2021002918 A1 CL 2021002918A1
- Authority
- CL
- Chile
- Prior art keywords
- oxymetazoline
- compositions
- methods
- treatment
- ocular disorders
- Prior art date
Links
- WYWIFABBXFUGLM-UHFFFAOYSA-N oxymetazoline Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C)=C1CC1=NCCN1 WYWIFABBXFUGLM-UHFFFAOYSA-N 0.000 title abstract 10
- 239000000203 mixture Substances 0.000 title abstract 5
- 229960001528 oxymetazoline Drugs 0.000 title abstract 5
- 208000022873 Ocular disease Diseases 0.000 title 1
- 206010015995 Eyelid ptosis Diseases 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 210000000744 eyelid Anatomy 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 201000003004 ptosis Diseases 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962844069P | 2019-05-06 | 2019-05-06 | |
| US201962843819P | 2019-05-06 | 2019-05-06 | |
| US16/715,998 US10814001B1 (en) | 2019-05-06 | 2019-12-16 | Oxymetazoline compositions |
| US16/716,014 US10799481B1 (en) | 2019-05-06 | 2019-12-16 | Compositions and methods for treating ocular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2021002918A1 true CL2021002918A1 (es) | 2022-08-19 |
Family
ID=72750169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2021002918A CL2021002918A1 (es) | 2019-05-06 | 2021-11-05 | Composiciones y métodos de oximetazolina para el tratamiento de trastornos oculares |
Country Status (17)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120225918A1 (en) * | 2011-03-03 | 2012-09-06 | Voom, Llc | Compositions and Methods for Non-Surgical Treatment of Ptosis |
| US10799481B1 (en) * | 2019-05-06 | 2020-10-13 | Rvl Pharmaceuticals, Inc. | Compositions and methods for treating ocular disorders |
| US20240156786A1 (en) | 2021-03-03 | 2024-05-16 | Voom, Llc | Compositions and methods for treatment of blepharitis |
| WO2023079427A1 (en) * | 2021-11-03 | 2023-05-11 | Avaca Pharma Private Limited | Ophthalmic compositions and methods thereof |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE51421B1 (en) | 1980-08-01 | 1986-12-24 | Smith & Nephew Ass | Ophthalmic compositions containing triamterene |
| US5459133A (en) | 1992-06-05 | 1995-10-17 | Telor Ophthalmic Pharmaceuticals, Inc. | Methods and products for treating presbyopia |
| US5888493A (en) | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| DE10337186A1 (de) * | 2003-08-13 | 2005-03-17 | Merck Patent Gmbh | Wässrige Wirkstoff-Lösung |
| US7812049B2 (en) | 2004-01-22 | 2010-10-12 | Vicept Therapeutics, Inc. | Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists |
| JP2006131628A (ja) * | 2004-10-08 | 2006-05-25 | Rohto Pharmaceut Co Ltd | オキシメタゾリン含有水性組成物 |
| US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| US8466174B2 (en) | 2006-03-17 | 2013-06-18 | Johnson & Johnson Vision Care, Inc. | Methods for stabilizing oxidatively unstable compositions |
| MX2008013783A (es) | 2006-04-26 | 2009-02-05 | Aciex Inc | Composiciones para el tratamiento y prevención de la hinchazón de los párpados. |
| WO2008070185A2 (en) | 2006-12-06 | 2008-06-12 | The Trustees Of Columbia University In The City Of New York | Method of stabilizing human eye tissue by reaction with nitrite and related agents such as nitro compounds |
| US20090281156A1 (en) * | 2007-12-21 | 2009-11-12 | Schering-Plough Healthcare Products, Inc, | Enhancing photostabilization of oxymetazoline |
| PL2262506T3 (pl) * | 2008-03-11 | 2014-09-30 | Alcon Res Ltd | Wysoce sflokulowane zawiesiny acetonidu triamcynolonu o niskiej lepkości do wystrzykiwania do ciała szklistego |
| CA2764477A1 (en) * | 2009-06-05 | 2010-12-09 | Aciex Therapeutics, Inc. | Ophthalmic formulations, methods of manufacture, and methods of using same |
| US20120082625A1 (en) | 2010-09-28 | 2012-04-05 | Michael Graeber | Combination treatment for rosacea |
| CN103249429A (zh) * | 2010-11-08 | 2013-08-14 | 希尔洛有限公司 | 缓冲的眼用组合物以及使用其的方法 |
| WO2012075319A2 (en) | 2010-12-03 | 2012-06-07 | Allergan, Inc. | Pharmaceutical cream compositions and methods of use |
| US20120225918A1 (en) | 2011-03-03 | 2012-09-06 | Voom, Llc | Compositions and Methods for Non-Surgical Treatment of Ptosis |
| WO2013177594A2 (en) | 2012-05-25 | 2013-11-28 | Xlear, Inc. | Xylitol-based anti-mucosal compositions and related methods and compositions |
| UA119324C2 (uk) | 2013-04-02 | 2019-06-10 | Теміс Медікер Лімітед | Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні |
| CN111465309B (zh) | 2013-09-18 | 2021-11-30 | 迈康尼股份公司 | 用于组件的改进的存储和处理的方法、系统和设备 |
| ES2796871T3 (es) | 2014-06-11 | 2020-11-30 | Epi Health Llc | Formulaciones de oximetazolina estabilizadas y sus usos |
| US11052094B2 (en) | 2015-05-29 | 2021-07-06 | Sydnexis, Inc. | D2O stabilized pharmaceutical formulations |
| US20170312335A1 (en) * | 2015-12-30 | 2017-11-02 | Lubris Llc | Topical use of prg4 for treatment of allergy and symptoms of inflammation |
| WO2017132410A1 (en) | 2016-01-26 | 2017-08-03 | Frank Litvack | Compositions and uses of alpha-adrenergic agents |
| CN105997856A (zh) * | 2016-06-24 | 2016-10-12 | 魏威 | 盐酸羟甲唑啉滴眼液及其制备方法 |
| US11246816B2 (en) | 2016-06-30 | 2022-02-15 | The Procter And Gamble Company | Shampoo compositions comprising a chelant |
| US10799481B1 (en) * | 2019-05-06 | 2020-10-13 | Rvl Pharmaceuticals, Inc. | Compositions and methods for treating ocular disorders |
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2019
- 2019-12-16 US US16/716,014 patent/US10799481B1/en active Active
- 2019-12-16 US US16/715,998 patent/US10814001B1/en active Active
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2020
- 2020-03-16 JP JP2020045468A patent/JP7141420B2/ja active Active
- 2020-04-01 CN CN202310901249.9A patent/CN117045596A/zh active Pending
- 2020-04-01 CN CN202010249167.7A patent/CN111888326B/zh active Active
- 2020-04-27 KR KR1020200050837A patent/KR102410503B1/ko active Active
- 2020-05-05 BR BR112021022404A patent/BR112021022404A2/pt unknown
- 2020-05-05 AU AU2020268329A patent/AU2020268329A1/en active Pending
- 2020-05-05 CA CA3139443A patent/CA3139443A1/en active Pending
- 2020-05-05 SG SG11202112272TA patent/SG11202112272TA/en unknown
- 2020-05-05 MX MX2021013516A patent/MX2021013516A/es unknown
- 2020-05-05 PE PE2021001852A patent/PE20220384A1/es unknown
- 2020-05-05 MA MA055895A patent/MA55895A/fr unknown
- 2020-05-05 WO PCT/US2020/031425 patent/WO2020227260A1/en not_active Ceased
- 2020-05-05 EP EP20729894.4A patent/EP3965737A1/en active Pending
- 2020-10-05 US US17/063,416 patent/US10940138B2/en active Active
- 2020-10-07 US US17/064,915 patent/US10898573B1/en active Active
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2021
- 2021-01-21 US US17/154,676 patent/US11103482B2/en active Active
- 2021-03-08 US US17/194,559 patent/US11324722B2/en active Active
- 2021-08-30 US US17/461,052 patent/US11311515B2/en active Active
- 2021-09-24 JP JP2021155526A patent/JP7705326B2/ja active Active
- 2021-11-04 IL IL287831A patent/IL287831A/en unknown
- 2021-11-05 CL CL2021002918A patent/CL2021002918A1/es unknown
- 2021-11-11 ZA ZA2021/08950A patent/ZA202108950B/en unknown
- 2021-11-11 CO CONC2021/0015265A patent/CO2021015265A2/es unknown
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2022
- 2022-04-25 US US17/728,860 patent/US11541036B2/en active Active
- 2022-05-09 US US17/662,494 patent/US11701343B2/en active Active
- 2022-06-14 KR KR1020220072209A patent/KR102663319B1/ko active Active
- 2022-11-11 ZA ZA2022/12328A patent/ZA202212328B/en unknown
- 2022-12-23 US US18/146,127 patent/US20230355587A1/en active Pending
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2023
- 2023-06-08 US US18/331,688 patent/US20240033250A1/en active Pending
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2024
- 2024-04-29 KR KR1020240057166A patent/KR102859351B1/ko active Active
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2025
- 2025-01-31 JP JP2025014721A patent/JP2025065198A/ja active Pending
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