CL2020001285A1 - Método de producción de un compuesto intermedio para sintetizar un medicamento. - Google Patents
Método de producción de un compuesto intermedio para sintetizar un medicamento.Info
- Publication number
- CL2020001285A1 CL2020001285A1 CL2020001285A CL2020001285A CL2020001285A1 CL 2020001285 A1 CL2020001285 A1 CL 2020001285A1 CL 2020001285 A CL2020001285 A CL 2020001285A CL 2020001285 A CL2020001285 A CL 2020001285A CL 2020001285 A1 CL2020001285 A1 CL 2020001285A1
- Authority
- CL
- Chile
- Prior art keywords
- synthesize
- drug
- production method
- intermediate compound
- protective group
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000001681 protective effect Effects 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 108010067722 Dipeptidyl Peptidase 4 Proteins 0.000 abstract 1
- 102100025012 Dipeptidyl peptidase 4 Human genes 0.000 abstract 1
- 241001247848 Phylica Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/02—Monohydroxylic acyclic alcohols
- C07C31/04—Methanol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/12—Saturated polycyclic compounds
- C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
- C07C61/13—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170153334 | 2017-11-16 | ||
| KR1020180126663A KR102184129B1 (ko) | 2017-11-16 | 2018-10-23 | 의약품 합성용 중간체 화합물의 제조 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2020001285A1 true CL2020001285A1 (es) | 2020-10-23 |
Family
ID=66680122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2020001285A CL2020001285A1 (es) | 2017-11-16 | 2020-05-15 | Método de producción de un compuesto intermedio para sintetizar un medicamento. |
Country Status (8)
| Country | Link |
|---|---|
| KR (1) | KR102184129B1 (pt) |
| CN (1) | CN111247127B (pt) |
| BR (1) | BR112020009568A2 (pt) |
| CL (1) | CL2020001285A1 (pt) |
| CO (1) | CO2020006788A2 (pt) |
| PE (1) | PE20210839A1 (pt) |
| PH (1) | PH12020550635A1 (pt) |
| RU (1) | RU2741389C1 (pt) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2721185A1 (de) * | 1977-05-11 | 1978-11-16 | Bayer Ag | Verfahren zur herstellung von substituierten vinylcyclopropancarbonsaeurebenzylestern |
| JPH04316526A (ja) * | 1991-04-15 | 1992-11-06 | Asahi Chem Ind Co Ltd | カルボン酸エステルのアルカリ加水分解法 |
| TW460452B (en) * | 1998-09-14 | 2001-10-21 | Rhodia Fiber & Amp Resin Inter | Process for the crystallization of carboxylic acid and process for manufacturing crystalline carboxylic acid |
| TWI357902B (en) * | 2005-04-01 | 2012-02-11 | Lg Life Science Ltd | Dipeptidyl peptidase-iv inhibiting compounds, meth |
| JP2008201719A (ja) * | 2007-02-20 | 2008-09-04 | Nippon Oil Corp | テトラカルボン酸およびその酸二無水物の製造方法 |
| AU2008341352B2 (en) * | 2007-12-21 | 2013-08-01 | Lg Chem, Ltd. | Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent |
| NZ607694A (en) * | 2010-09-03 | 2015-08-28 | Lg Life Sciences Ltd | Production method of intermediate compound for synthesizing medicament |
-
2018
- 2018-10-23 CN CN201880067548.4A patent/CN111247127B/zh active Active
- 2018-10-23 PE PE2020000586A patent/PE20210839A1/es unknown
- 2018-10-23 BR BR112020009568-0A patent/BR112020009568A2/pt unknown
- 2018-10-23 KR KR1020180126663A patent/KR102184129B1/ko active IP Right Grant
- 2018-10-23 RU RU2020114746A patent/RU2741389C1/ru active
-
2020
- 2020-05-15 CL CL2020001285A patent/CL2020001285A1/es unknown
- 2020-05-15 PH PH12020550635A patent/PH12020550635A1/en unknown
- 2020-05-29 CO CONC2020/0006788A patent/CO2020006788A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN111247127A (zh) | 2020-06-05 |
| CN111247127B (zh) | 2024-02-06 |
| BR112020009568A2 (pt) | 2021-03-09 |
| PH12020550635A1 (en) | 2021-02-22 |
| PE20210839A1 (es) | 2021-05-06 |
| KR20190056296A (ko) | 2019-05-24 |
| CO2020006788A2 (es) | 2020-06-09 |
| KR102184129B1 (ko) | 2020-11-27 |
| RU2741389C1 (ru) | 2021-01-25 |
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