CL2019003308A1 - Un sorbente polimérico, preparacion y uso del mismo. - Google Patents
Un sorbente polimérico, preparacion y uso del mismo.Info
- Publication number
- CL2019003308A1 CL2019003308A1 CL2019003308A CL2019003308A CL2019003308A1 CL 2019003308 A1 CL2019003308 A1 CL 2019003308A1 CL 2019003308 A CL2019003308 A CL 2019003308A CL 2019003308 A CL2019003308 A CL 2019003308A CL 2019003308 A1 CL2019003308 A1 CL 2019003308A1
- Authority
- CL
- Chile
- Prior art keywords
- sorbent
- polymers
- plasma
- lines
- cytokines
- Prior art date
Links
- 239000002594 sorbent Substances 0.000 title abstract 5
- 229920000642 polymer Polymers 0.000 abstract 4
- 102000004127 Cytokines Human genes 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 2
- 239000002158 endotoxin Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000003913 materials processing Methods 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
- B01J20/267—Cross-linked polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28057—Surface area, e.g. B.E.T specific surface area
- B01J20/28064—Surface area, e.g. B.E.T specific surface area being in the range 500-1000 m2/g
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28057—Surface area, e.g. B.E.T specific surface area
- B01J20/28066—Surface area, e.g. B.E.T specific surface area being more than 1000 m2/g
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/285—Porous sorbents based on polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3276—Copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
- B01J2220/44—Materials comprising a mixture of organic materials
- B01J2220/445—Materials comprising a mixture of organic materials comprising a mixture of polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
- B01J2220/48—Sorbents characterised by the starting material used for their preparation
- B01J2220/4812—Sorbents characterised by the starting material used for their preparation the starting material being of organic character
- B01J2220/4825—Polysaccharides or cellulose materials, e.g. starch, chitin, sawdust, wood, straw, cotton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- External Artificial Organs (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
LA INVENCIÓN RELACIONA UNA QUÍMICA DE POLÍMEROS, ESPECIFICAMENTE A POLÍMEROS SORBENTES DESTINADO A LA ELIMINACIÓN SELECTIVA DE CITOQUINAS Y ENDOTOXINAS BACTERIANAS DE LA SANGRE Y OTROS FLUIDOS CORPORALES, EN PARTICULAS PLASMA SANGUÍNEO, LINFA, ETC., DE IGUAL MANERA QUE DE SOLUCIONES ACUOSAS PROTÉICAS Y SOLUCIONES ACOSAS DE COMPUESTOS ORGÁNICOS, QUE TAMBIÉN CONTENGAN SALES INORGÁNICAS, ASÍ COMO UN MÉTODO DE PRODUCCIÓN DE DICHOS MATERIALES DE SORBCIÓN PROCESANDO LÍQUIDOS USANDO DICHOS POLÍMEROS SORBENTES. EL RESULTADO TÉCNICO CONSISTE EN PROVEER UN SORBENTE QUE ES CAPAZ DE REMOVER TANTO CITOQUINAS COMO ENDOTOXINAS BACTERIANAS, EN MEJORAR LA SELECTIVIDAD DE LOS POLÍMEROS SORBENTES CON RESPECTO A LOS COMPUESTOS ASÍ COMO EN PROVEER UN MÉTODO SIMPLE Y EFECTIVO DE PRODUCIR DICHO SORBENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2017117852A RU2653125C1 (ru) | 2017-05-23 | 2017-05-23 | Полимерный сорбент, способ его получения и использования |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019003308A1 true CL2019003308A1 (es) | 2020-03-20 |
Family
ID=62105693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019003308A CL2019003308A1 (es) | 2017-05-23 | 2019-11-18 | Un sorbente polimérico, preparacion y uso del mismo. |
Country Status (16)
Country | Link |
---|---|
US (1) | US11602732B2 (es) |
EP (1) | EP3630352B1 (es) |
JP (1) | JP7221946B2 (es) |
KR (1) | KR102545787B1 (es) |
CN (1) | CN110662604B (es) |
BR (1) | BR112019024069B1 (es) |
CA (1) | CA3063342A1 (es) |
CL (1) | CL2019003308A1 (es) |
CO (1) | CO2019012780A2 (es) |
IL (1) | IL270581B1 (es) |
MA (1) | MA48786A (es) |
MX (1) | MX2019013996A (es) |
PE (1) | PE20200246A1 (es) |
PL (1) | PL3630352T3 (es) |
RU (1) | RU2653125C1 (es) |
WO (1) | WO2018217137A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109942737B (zh) * | 2019-03-13 | 2020-12-08 | 南京大学 | 粒径均匀的两亲性聚合物微球材料、制备方法和应用 |
RU2738607C1 (ru) * | 2020-02-05 | 2020-12-14 | Федеральное государственное бюджетное учреждение науки Физический институт им. П.Н. Лебедева Российской академии наук (ФИАН) | Способ получения малоплотных сверхсшитых полимеров монолитного типа |
CN111569842A (zh) * | 2020-06-02 | 2020-08-25 | 威海威高生命科技有限公司 | 一种复合型吸附剂及其制备方法 |
CN111686704B (zh) * | 2020-07-02 | 2023-08-08 | 苏州仝康医疗科技有限公司 | 一种血液净化吸附剂及其制备方法和应用 |
CN114106407B (zh) * | 2020-08-31 | 2023-09-29 | 泉州师范学院 | 一种血液灌流吸附剂及其制备方法 |
CN114106406A (zh) * | 2020-08-31 | 2022-03-01 | 泉州师范学院 | 一种血液灌流用超高交联聚多孔树脂吸附剂及其制备方法 |
CN112255356B (zh) * | 2020-10-21 | 2022-07-08 | 山西省化工研究所(有限公司) | 一种塑料中双酚类抗氧剂的定性定量分析方法 |
RU2765188C1 (ru) * | 2020-11-03 | 2022-01-26 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ получения селективного сорбента для твердофазной экстракции |
CN112973277B (zh) * | 2021-03-17 | 2022-06-14 | 济南大学 | 一种超支化型高分子聚合物滤垫的制备及其应用 |
CN114405488B (zh) * | 2022-01-12 | 2023-08-25 | 江苏贝美医疗科技有限公司 | 一种蛋白结合类毒素血液灌流吸附剂及其制备方法与应用 |
CN114950383B (zh) * | 2022-04-08 | 2024-02-06 | 淄博康贝医疗器械有限公司 | 血液净化用细胞因子吸附剂及制备方法 |
CN115894752A (zh) * | 2022-11-22 | 2023-04-04 | 航天特种材料及工艺技术研究所 | 一种环型聚合物的合成方法 |
CN115920861B (zh) * | 2022-12-23 | 2024-07-12 | 中美华世通生物医药科技(武汉)股份有限公司 | 一种吸附剂、其制备方法及应用 |
CN117696018B (zh) * | 2023-12-29 | 2024-07-16 | 苏州见远检测技术有限公司 | 一种用于去除自来水余氯的前处理过滤介质的制备方法 |
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BE756082A (fr) | 1969-09-12 | 1971-03-11 | I Elementoorganiche Kih Soedin | Squelettes macroreticulaires de polystyrene pour resines echangeuses d'ions et leur procede de preparation ( |
CA1130500A (en) * | 1978-07-24 | 1982-08-24 | Samuel F. Reed, Jr. | Polymeric adsorbents from macroreticular polymer beads |
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2017
- 2017-05-23 RU RU2017117852A patent/RU2653125C1/ru active
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2018
- 2018-05-17 WO PCT/RU2018/050052 patent/WO2018217137A1/en active Application Filing
- 2018-05-17 PE PE2019002427A patent/PE20200246A1/es unknown
- 2018-05-17 JP JP2020516368A patent/JP7221946B2/ja active Active
- 2018-05-17 IL IL270581A patent/IL270581B1/en unknown
- 2018-05-17 CA CA3063342A patent/CA3063342A1/en active Pending
- 2018-05-17 EP EP18734983.2A patent/EP3630352B1/en active Active
- 2018-05-17 KR KR1020197037821A patent/KR102545787B1/ko active IP Right Grant
- 2018-05-17 MX MX2019013996A patent/MX2019013996A/es unknown
- 2018-05-17 MA MA048786A patent/MA48786A/fr unknown
- 2018-05-17 PL PL18734983.2T patent/PL3630352T3/pl unknown
- 2018-05-17 CN CN201880034066.9A patent/CN110662604B/zh active Active
- 2018-05-17 BR BR112019024069-1A patent/BR112019024069B1/pt active IP Right Grant
- 2018-05-17 US US16/616,403 patent/US11602732B2/en active Active
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2019
- 2019-11-15 CO CONC2019/0012780A patent/CO2019012780A2/es unknown
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KR102545787B1 (ko) | 2023-06-20 |
CN110662604B (zh) | 2023-08-04 |
CA3063342A1 (en) | 2018-11-29 |
CO2019012780A2 (es) | 2020-02-18 |
IL270581A (es) | 2020-01-30 |
JP2020523197A (ja) | 2020-08-06 |
WO2018217137A1 (en) | 2018-11-29 |
US20200139348A1 (en) | 2020-05-07 |
BR112019024069A2 (pt) | 2020-06-02 |
PE20200246A1 (es) | 2020-02-03 |
EP3630352A1 (en) | 2020-04-08 |
KR20200010442A (ko) | 2020-01-30 |
US11602732B2 (en) | 2023-03-14 |
MA48786A (fr) | 2020-04-08 |
JP7221946B2 (ja) | 2023-02-14 |
RU2653125C1 (ru) | 2018-05-07 |
CN110662604A (zh) | 2020-01-07 |
IL270581B1 (en) | 2024-07-01 |
EP3630352B1 (en) | 2024-02-14 |
BR112019024069B1 (pt) | 2023-09-26 |
MX2019013996A (es) | 2020-02-05 |
PL3630352T3 (pl) | 2024-06-17 |
EP3630352C0 (en) | 2024-02-14 |
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