CL2018002457A1 - Tratamiento de condiciones oculares alérgicas con ciclodextrinas - Google Patents

Tratamiento de condiciones oculares alérgicas con ciclodextrinas

Info

Publication number
CL2018002457A1
CL2018002457A1 CL2018002457A CL2018002457A CL2018002457A1 CL 2018002457 A1 CL2018002457 A1 CL 2018002457A1 CL 2018002457 A CL2018002457 A CL 2018002457A CL 2018002457 A CL2018002457 A CL 2018002457A CL 2018002457 A1 CL2018002457 A1 CL 2018002457A1
Authority
CL
Chile
Prior art keywords
treatment
cyclodextrins
eye conditions
allergic eye
cyclodextrine
Prior art date
Application number
CL2018002457A
Other languages
English (en)
Inventor
Todd Brady
Scott Young
Susan Macdonald
Stephen Gitu Machatha
David Clark
Original Assignee
Aldeyra Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aldeyra Therapeutics Inc filed Critical Aldeyra Therapeutics Inc
Publication of CL2018002457A1 publication Critical patent/CL2018002457A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A MÉTODOS PARA TRATAR ALERGIAS OCULARES Y CONJUNTIVITIS ALÉRGICA CON CICLODEXTRINA. TAMBIÉN SE PROPORCIONAN COMPOSICIONES OFTÁLMICAS DE CICLODEXTRINA PARA ADMINISTRACIÓN TÓPICA.
CL2018002457A 2016-02-28 2018-08-28 Tratamiento de condiciones oculares alérgicas con ciclodextrinas CL2018002457A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662300907P 2016-02-28 2016-02-28
US201662315488P 2016-03-30 2016-03-30

Publications (1)

Publication Number Publication Date
CL2018002457A1 true CL2018002457A1 (es) 2018-11-09

Family

ID=59685756

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002457A CL2018002457A1 (es) 2016-02-28 2018-08-28 Tratamiento de condiciones oculares alérgicas con ciclodextrinas

Country Status (13)

Country Link
US (1) US10426790B2 (es)
EP (1) EP3419633A4 (es)
JP (2) JP7450242B2 (es)
KR (1) KR20180116416A (es)
CN (2) CN109069530A (es)
AU (1) AU2017224249A1 (es)
BR (1) BR112018069533A2 (es)
CA (1) CA3016759A1 (es)
CL (1) CL2018002457A1 (es)
CO (1) CO2018009099A2 (es)
IL (1) IL261419A (es)
MX (1) MX2018010292A (es)
WO (1) WO2017147617A1 (es)

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CA2996183A1 (en) 2015-08-21 2017-03-02 Aldeyra Therapeutics, Inc. Deuterated compounds and uses thereof
EP3454858A4 (en) 2016-05-09 2020-01-15 Aldeyra Therapeutics, Inc. POLYTHERAPY OF DISORDERS AND INFLAMMATORY EYE DISEASES
ES2968462T3 (es) 2017-03-16 2024-05-09 Aldeyra Therapeutics Inc Sal polimórfica de 6-cloro-3-amino-2(2-hidroxiprolil) quinolina y usos de la misma
MX2020003425A (es) 2017-10-10 2020-07-29 Aldeyra Therapeutics Inc Tratamiento de trastornos inflamatorios.
WO2020018498A1 (en) * 2018-07-16 2020-01-23 Aldeyra Therapeutics, Inc. Cyclodextrin formulations
WO2020033344A1 (en) 2018-08-06 2020-02-13 Aldeyra Therapeutics, Inc. Polymorphic compounds and uses thereof
CN115869258A (zh) * 2018-09-25 2023-03-31 奥尔德拉医疗公司 用于治疗干眼病的调配物
US20210317385A1 (en) * 2018-10-02 2021-10-14 Aldeyra Therapeutics, Inc. Contact lens solutions and kits
CN109646684B (zh) * 2019-02-18 2021-05-28 天津医科大学总医院 环孢菌素h环糊精及其用途
JP2022526917A (ja) * 2019-03-26 2022-05-27 アルデイラ セラピューティクス， インコーポレイテッド 眼科用製剤およびその使用
US10744153B1 (en) 2019-07-01 2020-08-18 Cloudbreak Therapeutics Llc Compositions and methods for treating meibomian gland dysfunction
CN110752039A (zh) * 2019-10-30 2020-02-04 湖南财政经济学院 通过电子病历判断过敏原与预测过敏情况的定量评分系统
WO2024091659A1 (en) * 2022-10-28 2024-05-02 Aldeyra Therapeutics, Inc. Modified cyclodextrins and ophthalmic uses thereof

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Also Published As

Publication number Publication date
JP2019507756A (ja) 2019-03-22
CN109069530A (zh) 2018-12-21
JP7450242B2 (ja) 2024-03-15
CN116531400A (zh) 2023-08-04
US10426790B2 (en) 2019-10-01
US20170266220A1 (en) 2017-09-21
IL261419A (en) 2018-10-31
CO2018009099A2 (es) 2018-10-10
EP3419633A1 (en) 2019-01-02
BR112018069533A2 (pt) 2019-04-16
CA3016759A1 (en) 2017-08-31
WO2017147617A1 (en) 2017-08-31
JP2022048282A (ja) 2022-03-25
MX2018010292A (es) 2018-09-27
KR20180116416A (ko) 2018-10-24
AU2017224249A1 (en) 2018-09-13
EP3419633A4 (en) 2019-10-30

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