CL2017000645A1 - Síntesis de ent-progesterona e intermediarios de la misma - Google Patents
Síntesis de ent-progesterona e intermediarios de la mismaInfo
- Publication number
- CL2017000645A1 CL2017000645A1 CL2017000645A CL2017000645A CL2017000645A1 CL 2017000645 A1 CL2017000645 A1 CL 2017000645A1 CL 2017000645 A CL2017000645 A CL 2017000645A CL 2017000645 A CL2017000645 A CL 2017000645A CL 2017000645 A1 CL2017000645 A1 CL 2017000645A1
- Authority
- CL
- Chile
- Prior art keywords
- progesterone
- ent
- synthesis
- intermediates
- intermediaries
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 229960003387 progesterone Drugs 0.000 title abstract 2
- 239000000186 progesterone Substances 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J61/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one or two atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/0805—Compounds with Si-C or Si-Si linkages comprising only Si, C or H atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5022—Aromatic phosphines (P-C aromatic linkage)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
- C07J15/005—Retrosteroids (9 beta 10 alfa)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- C07J75/005—Preparation of steroids by cyclization of non-steroid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051900P | 2014-09-17 | 2014-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2017000645A1 true CL2017000645A1 (es) | 2018-09-14 |
Family
ID=55533837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2017000645A CL2017000645A1 (es) | 2014-09-17 | 2017-03-16 | Síntesis de ent-progesterona e intermediarios de la misma |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20160108081A1 (zh) |
| EP (1) | EP3194418B1 (zh) |
| JP (1) | JP2017535596A (zh) |
| CN (1) | CN108064228A (zh) |
| AR (1) | AR101951A1 (zh) |
| AU (1) | AU2015317651A1 (zh) |
| BR (1) | BR112017005167A2 (zh) |
| CA (1) | CA2961628A1 (zh) |
| CL (1) | CL2017000645A1 (zh) |
| EA (1) | EA201790428A1 (zh) |
| ES (1) | ES2910225T3 (zh) |
| IL (1) | IL251237A0 (zh) |
| MA (1) | MA39411A (zh) |
| PH (1) | PH12017500499A1 (zh) |
| SG (1) | SG11201702115SA (zh) |
| TN (1) | TN2017000088A1 (zh) |
| TW (1) | TW201619183A (zh) |
| UY (1) | UY36306A (zh) |
| WO (1) | WO2016044558A1 (zh) |
| ZA (1) | ZA201701976B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015012902A (es) * | 2013-03-15 | 2016-07-20 | Univ Florida State Res Found | Sintesis de ent-progesterona e intermediarios de la misma. |
| IT201700004904A1 (it) * | 2017-01-18 | 2018-07-18 | Ind Chimica Srl | PROCESSO PER LA PREPARAZIONE DI 9β,10α-PROGESTERONE (RETROPROGESTERONE) |
| GB202203328D0 (en) | 2022-03-10 | 2022-04-27 | Givaudan Sa | Organic compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2623071A (en) * | 1948-05-13 | 1952-12-23 | Synor Res Lab Inc | Preparation of substituted cyclopentenones |
| JPS4926214A (zh) * | 1971-07-14 | 1974-03-08 | ||
| US4189431A (en) * | 1975-08-04 | 1980-02-19 | The Board of Trustees of Leland Stanford Junior University | Alkinyl terminating groups in biogenetic-like cyclizations to steroids |
| JP2001247562A (ja) * | 2000-03-07 | 2001-09-11 | Daicel Chem Ind Ltd | アミド化合物及びその製造方法 |
| CA2955684A1 (en) * | 2008-02-26 | 2009-09-03 | Emory University | Steroid analogues for neuroprotection |
| WO2010088409A2 (en) * | 2009-01-30 | 2010-08-05 | Emory University | Methods of neuroprotection using neuroprotective steroids and a vitamin d |
| HUE029002T2 (en) * | 2010-12-17 | 2017-01-30 | Mitsubishi Tanabe Pharma Corp | Continuous aricyclic compounds |
| MX2015012902A (es) * | 2013-03-15 | 2016-07-20 | Univ Florida State Res Found | Sintesis de ent-progesterona e intermediarios de la misma. |
-
2015
- 2015-09-17 AU AU2015317651A patent/AU2015317651A1/en not_active Abandoned
- 2015-09-17 EA EA201790428A patent/EA201790428A1/ru unknown
- 2015-09-17 CA CA2961628A patent/CA2961628A1/en not_active Abandoned
- 2015-09-17 JP JP2017534902A patent/JP2017535596A/ja active Pending
- 2015-09-17 CN CN201580055155.8A patent/CN108064228A/zh active Pending
- 2015-09-17 BR BR112017005167A patent/BR112017005167A2/pt not_active Application Discontinuation
- 2015-09-17 AR ARP150102995A patent/AR101951A1/es unknown
- 2015-09-17 EP EP15841632.1A patent/EP3194418B1/en active Active
- 2015-09-17 US US14/857,554 patent/US20160108081A1/en not_active Abandoned
- 2015-09-17 WO PCT/US2015/050631 patent/WO2016044558A1/en active Application Filing
- 2015-09-17 SG SG11201702115SA patent/SG11201702115SA/en unknown
- 2015-09-17 MA MA039411A patent/MA39411A/fr unknown
- 2015-09-17 TW TW104130836A patent/TW201619183A/zh unknown
- 2015-09-17 UY UY0001036306A patent/UY36306A/es not_active Application Discontinuation
- 2015-09-17 TN TN2017000088A patent/TN2017000088A1/en unknown
- 2015-09-17 ES ES15841632T patent/ES2910225T3/es active Active
-
2017
- 2017-03-15 PH PH12017500499A patent/PH12017500499A1/en unknown
- 2017-03-16 CL CL2017000645A patent/CL2017000645A1/es unknown
- 2017-03-16 IL IL251237A patent/IL251237A0/en unknown
- 2017-03-22 ZA ZA2017/01976A patent/ZA201701976B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TN2017000088A1 (en) | 2018-07-04 |
| SG11201702115SA (en) | 2017-04-27 |
| PH12017500499A1 (en) | 2017-08-30 |
| US20160108081A1 (en) | 2016-04-21 |
| EP3194418A4 (en) | 2018-12-12 |
| CA2961628A1 (en) | 2016-03-24 |
| BR112017005167A2 (pt) | 2018-06-19 |
| MA39411A (fr) | 2016-03-24 |
| EA201790428A1 (ru) | 2017-08-31 |
| UY36306A (es) | 2016-04-29 |
| EP3194418B1 (en) | 2021-12-15 |
| ZA201701976B (en) | 2019-06-26 |
| TW201619183A (zh) | 2016-06-01 |
| AU2015317651A1 (en) | 2017-04-06 |
| CN108064228A (zh) | 2018-05-22 |
| IL251237A0 (en) | 2017-05-29 |
| JP2017535596A (ja) | 2017-11-30 |
| ES2910225T3 (es) | 2022-05-12 |
| WO2016044558A1 (en) | 2016-03-24 |
| EP3194418A1 (en) | 2017-07-26 |
| AR101951A1 (es) | 2017-01-25 |
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