CL2014003276A1 - Uso de polisacárido de poli n-acetil glucosamina (pnag) para prevenir o tratar una infección por un patógeno positivo a pnag sin ica/pga; composición farmacéutica que comprende dicho polisacárido; y uso de anticuerpo contra pnag para tratar infección por ciertos patógenos. - Google Patents
Uso de polisacárido de poli n-acetil glucosamina (pnag) para prevenir o tratar una infección por un patógeno positivo a pnag sin ica/pga; composición farmacéutica que comprende dicho polisacárido; y uso de anticuerpo contra pnag para tratar infección por ciertos patógenos.Info
- Publication number
- CL2014003276A1 CL2014003276A1 CL2014003276A CL2014003276A CL2014003276A1 CL 2014003276 A1 CL2014003276 A1 CL 2014003276A1 CL 2014003276 A CL2014003276 A CL 2014003276A CL 2014003276 A CL2014003276 A CL 2014003276A CL 2014003276 A1 CL2014003276 A1 CL 2014003276A1
- Authority
- CL
- Chile
- Prior art keywords
- pnag
- treat
- polysaccharide
- infection
- ica
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title 2
- 244000052769 pathogen Species 0.000 title 2
- 229920001282 polysaccharide Polymers 0.000 title 2
- 239000005017 polysaccharide Substances 0.000 title 2
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 title 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 title 1
- 150000004676 glycans Chemical class 0.000 title 1
- 229950006780 n-acetylglucosamine Drugs 0.000 title 1
- 230000001717 pathogenic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 poly n-acetyl glucosamine polysaccharide Chemical class 0.000 title 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
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- A61K39/085—Staphylococcus
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- A61K39/0002—Fungal antigens, e.g. Trichophyton, Aspergillus, Candida
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- A61K39/002—Protozoa antigens
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- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
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- A61K39/0208—Specific bacteria not otherwise provided for
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Microbiology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Biochemistry (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261653389P | 2012-05-30 | 2012-05-30 | |
| US201361827661P | 2013-05-26 | 2013-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014003276A1 true CL2014003276A1 (es) | 2015-06-12 |
Family
ID=49673891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014003276A CL2014003276A1 (es) | 2012-05-30 | 2014-11-28 | Uso de polisacárido de poli n-acetil glucosamina (pnag) para prevenir o tratar una infección por un patógeno positivo a pnag sin ica/pga; composición farmacéutica que comprende dicho polisacárido; y uso de anticuerpo contra pnag para tratar infección por ciertos patógenos. |
Country Status (19)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2501077C (en) * | 2002-11-12 | 2016-06-21 | Gerald B. Pier | Polysaccharide vaccine for staphylococcal infections |
| PT1745075E (pt) | 2004-04-21 | 2013-06-17 | Brigham & Womens Hospital | Péptidos de ligação a poli-n-acetilglucosamina (pnag/dpnag) e métodos da sua utilização |
| CN105085349B (zh) | 2008-07-21 | 2018-02-09 | 布赖汉姆妇女医院 | 与合成的β‑1,6 葡糖胺寡糖相关的方法和组合物 |
| WO2016069888A1 (en) | 2014-10-29 | 2016-05-06 | University Of Wyoming | Compositions and methods for making and using hydrolytic enzymes for degrading polysaccharides made by foodborne pathogenic bacteria |
| MX2019002489A (es) | 2016-09-02 | 2019-10-21 | Sanofi Pasteur Inc | Vacuna contra neisseria meningitidis. |
| CA3101239A1 (en) | 2018-05-23 | 2019-11-28 | Meharry Medical College | Glycan strand or oligosaccharide derived from gram-positive bacteria, method of making thereof and use thereof for inhibiting hiv or hbv replication (formerly: molecules derived from gram-positive bacteria) |
| US12397014B2 (en) | 2019-02-05 | 2025-08-26 | The Brigham And Women's Hospital, Inc. | Polysaccharide compositions for use in treating filariasis |
| CN110638830A (zh) * | 2019-09-29 | 2020-01-03 | 深圳市生命谷生命科技研究院 | 消化泥鳅多糖调节免疫功能或治疗免疫相关疾病的用途 |
| US11173199B2 (en) | 2019-11-13 | 2021-11-16 | Alopexx Inc. | Low contaminant compositions |
| KR20220107001A (ko) * | 2019-11-22 | 2022-08-01 | 알로펙스, 인크. | Pnag 포함 미생물에 대한 연속 치료를 제공하는 방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1319315A (en) | 1969-06-19 | 1973-06-06 | Citizen Watch Co Ltd | Calendar timepiece |
| US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5565354A (en) | 1986-09-05 | 1996-10-15 | Sandoz Ltd. | Production of human monoclonal antibodies specific for hepatitis B surface antigen |
| US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| ATE400296T1 (de) | 1999-12-02 | 2008-07-15 | Novartis Vaccines & Diagnostic | Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung |
| CA2501077C (en) * | 2002-11-12 | 2016-06-21 | Gerald B. Pier | Polysaccharide vaccine for staphylococcal infections |
| PT1745075E (pt) * | 2004-04-21 | 2013-06-17 | Brigham & Womens Hospital | Péptidos de ligação a poli-n-acetilglucosamina (pnag/dpnag) e métodos da sua utilização |
| CN105085349B (zh) | 2008-07-21 | 2018-02-09 | 布赖汉姆妇女医院 | 与合成的β‑1,6 葡糖胺寡糖相关的方法和组合物 |
| US12397014B2 (en) * | 2019-02-05 | 2025-08-26 | The Brigham And Women's Hospital, Inc. | Polysaccharide compositions for use in treating filariasis |
-
2013
- 2013-05-30 SG SG10201609902YA patent/SG10201609902YA/en unknown
- 2013-05-30 SG SG10201911609XA patent/SG10201911609XA/en unknown
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