CL2013003492A1 - Procedimiento de preparacion de 6-[7-hidroxi-6,7-dihidro-5h-pirrolo[1,2-c]imidazol-7-il]-n-metil-2-naftamida. - Google Patents

Procedimiento de preparacion de 6-[7-hidroxi-6,7-dihidro-5h-pirrolo[1,2-c]imidazol-7-il]-n-metil-2-naftamida.

Info

Publication number
CL2013003492A1
CL2013003492A1 CL2013003492A CL2013003492A CL2013003492A1 CL 2013003492 A1 CL2013003492 A1 CL 2013003492A1 CL 2013003492 A CL2013003492 A CL 2013003492A CL 2013003492 A CL2013003492 A CL 2013003492A CL 2013003492 A1 CL2013003492 A1 CL 2013003492A1
Authority
CL
Chile
Prior art keywords
naphthamide
pyrrolo
imidazol
dihydro
hydroxy
Prior art date
Application number
CL2013003492A
Other languages
English (en)
Spanish (es)
Inventor
Yoichi Kawabata
Yasuhiro Sawai
Kazuaki Kanno
Naotaka Sawada
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46458578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013003492(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of CL2013003492A1 publication Critical patent/CL2013003492A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CL2013003492A 2011-06-15 2013-12-05 Procedimiento de preparacion de 6-[7-hidroxi-6,7-dihidro-5h-pirrolo[1,2-c]imidazol-7-il]-n-metil-2-naftamida. CL2013003492A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011133712 2011-06-15

Publications (1)

Publication Number Publication Date
CL2013003492A1 true CL2013003492A1 (es) 2014-07-18

Family

ID=46458578

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003492A CL2013003492A1 (es) 2011-06-15 2013-12-05 Procedimiento de preparacion de 6-[7-hidroxi-6,7-dihidro-5h-pirrolo[1,2-c]imidazol-7-il]-n-metil-2-naftamida.

Country Status (27)

Country Link
US (2) US9278938B2 (enExample)
EP (1) EP2721010B1 (enExample)
JP (1) JP6082353B2 (enExample)
KR (1) KR20140028069A (enExample)
CN (1) CN103608334B (enExample)
AR (1) AR086926A1 (enExample)
AU (1) AU2012270496A1 (enExample)
BR (1) BR112013030888A2 (enExample)
CA (1) CA2838971C (enExample)
CL (1) CL2013003492A1 (enExample)
CO (1) CO6852075A2 (enExample)
CR (1) CR20130655A (enExample)
DO (1) DOP2013000287A (enExample)
EA (1) EA201490019A1 (enExample)
EC (1) ECSP14013128A (enExample)
ES (1) ES2554454T3 (enExample)
IL (1) IL229566A0 (enExample)
MA (1) MA35809B1 (enExample)
MX (1) MX2013014009A (enExample)
PE (1) PE20141326A1 (enExample)
PH (1) PH12013502567A1 (enExample)
SG (1) SG195036A1 (enExample)
TN (1) TN2013000481A1 (enExample)
TW (1) TW201307295A (enExample)
UY (1) UY34130A (enExample)
WO (1) WO2012173280A1 (enExample)
ZA (1) ZA201308884B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016054129A1 (en) * 2014-09-30 2016-04-07 Stc.Unm Graphene-based inorganic-organic hybrid materials and separation of racemic mixtures
US20200033307A1 (en) * 2018-07-25 2020-01-30 Honeywell International Inc. Method of determining an amount of water in a sample using a derivative of imidazole and a hydrogen halide donor
KR102253950B1 (ko) * 2019-07-24 2021-05-20 (주)에니켐텍 신규한 메데토미딘 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5832880A (ja) * 1981-08-24 1983-02-25 Isukura Sangyo Kk ハリントニンの部分合成方法
US6713632B1 (en) 1999-06-22 2004-03-30 Takeda Chemical Industries, Ltd. Process for the preparation of imidazole derivatives
PE20010781A1 (es) 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
DE10031604A1 (de) 2000-06-29 2002-01-17 Consortium Elektrochem Ind Verfahren zur Herstellung von beta-Hydroxy- und beta-Aminocarbonylverbindungen
TWI306099B (en) 2000-11-17 2009-02-11 Takeda Chemical Industries Ltd Novel imidazole derivatives, production method thereof and use thereof
CN1289434C (zh) 2002-01-04 2006-12-13 皇家飞利浦电子股份有限公司 烧结体和电灯
US7662974B2 (en) * 2002-01-10 2010-02-16 Takeda Pharmaceutical Company Limited Process for producing fused imidazole compound, reformatsky reagent in stable form, and process for producing the same
EP1394140A1 (de) * 2002-08-14 2004-03-03 Consortium für elektrochemische Industrie GmbH Enantioselektives Reformatsky-Verfahren zur Herstellung von optisch aktiven Alkoholen, Aminen und deren Derivaten
EP2164409B1 (en) 2007-06-29 2018-08-08 Atheromed, Inc. Atherectomy system

Also Published As

Publication number Publication date
ECSP14013128A (es) 2014-02-28
ZA201308884B (en) 2015-02-25
EA201490019A1 (ru) 2014-04-30
CN103608334A (zh) 2014-02-26
CA2838971C (en) 2019-07-30
AU2012270496A1 (en) 2013-12-19
JP6082353B2 (ja) 2017-02-15
CN103608334B (zh) 2015-12-23
US20140100373A1 (en) 2014-04-10
US10005780B2 (en) 2018-06-26
SG195036A1 (en) 2013-12-30
TW201307295A (zh) 2013-02-16
PH12013502567A1 (en) 2014-01-27
CO6852075A2 (es) 2014-01-30
DOP2013000287A (es) 2014-02-16
MX2013014009A (es) 2014-03-12
AR086926A1 (es) 2014-01-29
EP2721010B1 (en) 2015-09-09
TN2013000481A1 (en) 2015-03-30
CR20130655A (es) 2014-03-03
ES2554454T3 (es) 2015-12-21
CA2838971A1 (en) 2012-12-20
UY34130A (es) 2013-01-31
EP2721010A1 (en) 2014-04-23
PE20141326A1 (es) 2014-10-16
JP2014520066A (ja) 2014-08-21
BR112013030888A2 (pt) 2017-03-21
MA35809B1 (fr) 2014-12-01
US9278938B2 (en) 2016-03-08
WO2012173280A1 (en) 2012-12-20
US20160244454A1 (en) 2016-08-25
KR20140028069A (ko) 2014-03-07
IL229566A0 (en) 2014-01-30

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CL2013003492A1 (es) Procedimiento de preparacion de 6-[7-hidroxi-6,7-dihidro-5h-pirrolo[1,2-c]imidazol-7-il]-n-metil-2-naftamida.