CL2013001153A1 - Compuestos derivados de carboxilato de fenilcetona y sus sales; composicion farmaceutica que los comprende; y su uso para la prevencion o tratamiento de un trastorno hematologico, una enfermedad inflamatoria, un trastorno renal o una disfuncion de organos relacionada con fibrosis. - Google Patents

Compuestos derivados de carboxilato de fenilcetona y sus sales; composicion farmaceutica que los comprende; y su uso para la prevencion o tratamiento de un trastorno hematologico, una enfermedad inflamatoria, un trastorno renal o una disfuncion de organos relacionada con fibrosis.

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Publication number
CL2013001153A1
CL2013001153A1 CL2013001153A CL2013001153A CL2013001153A1 CL 2013001153 A1 CL2013001153 A1 CL 2013001153A1 CL 2013001153 A CL2013001153 A CL 2013001153A CL 2013001153 A CL2013001153 A CL 2013001153A CL 2013001153 A1 CL2013001153 A1 CL 2013001153A1
Authority
CL
Chile
Prior art keywords
disorder
fibrosis
prevention
salts
treatment
Prior art date
Application number
CL2013001153A
Other languages
English (en)
Spanish (es)
Inventor
Lyne Gagnon
Brigitte Grouix
Pierre Laurin
Christopher Penney
Boulos Zacharie
Shaun Abbott
Jean-Francois Bienvenu
Original Assignee
Prometic Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45992998&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013001153(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prometic Biosciences Inc filed Critical Prometic Biosciences Inc
Publication of CL2013001153A1 publication Critical patent/CL2013001153A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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    • C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
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    • C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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CL2013001153A 2010-10-27 2013-04-26 Compuestos derivados de carboxilato de fenilcetona y sus sales; composicion farmaceutica que los comprende; y su uso para la prevencion o tratamiento de un trastorno hematologico, una enfermedad inflamatoria, un trastorno renal o una disfuncion de organos relacionada con fibrosis. CL2013001153A1 (es)

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US40706810P 2010-10-27 2010-10-27

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CL2013001153A1 true CL2013001153A1 (es) 2014-01-10

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KR101870468B1 (ko) 2018-06-22
ZA201303032B (en) 2014-06-25
KR20130140745A (ko) 2013-12-24
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IL225600A0 (en) 2013-06-27
AU2011320057A1 (en) 2013-05-09
BR112013010508A8 (pt) 2021-07-27
EP2632885B1 (en) 2018-01-03
US9475750B2 (en) 2016-10-25
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EP2632885A1 (en) 2013-09-04
PH12013500763A1 (en) 2013-06-24
BR112013010508B8 (pt) 2021-12-07
MX348253B (es) 2017-05-31
EP2632885A4 (en) 2015-08-26
EA201370104A1 (ru) 2013-08-30
AU2011320057B2 (en) 2016-02-25
MX2013004833A (es) 2013-06-03
MY164375A (en) 2017-12-15
NZ610853A (en) 2015-05-29
DK2632885T3 (en) 2018-04-16
PH12013500763B1 (en) 2018-07-04
SG190035A1 (en) 2013-06-28
BR112013010508B1 (pt) 2021-08-10
CN103298777A (zh) 2013-09-11
TWI526427B (zh) 2016-03-21
ES2664816T3 (es) 2018-04-23
CA2816084C (en) 2019-10-29
JP2016210814A (ja) 2016-12-15
EA022988B9 (ru) 2016-08-31
PT2632885T (pt) 2018-04-04
BR112013010508A2 (pt) 2016-08-02
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