CL2009000985A1 - Composicion oftalmica que comprende entre 0,16 y 0,19% p/v de un galactomanano, alrededor de 0,7% p/v de un borato, cis-diol y menos de 5 ppm de concentracion de cationes divalentes; y su uso para lubricar el ojo. - Google Patents

Composicion oftalmica que comprende entre 0,16 y 0,19% p/v de un galactomanano, alrededor de 0,7% p/v de un borato, cis-diol y menos de 5 ppm de concentracion de cationes divalentes; y su uso para lubricar el ojo.

Info

Publication number
CL2009000985A1
CL2009000985A1 CL2009000985A CL2009000985A CL2009000985A1 CL 2009000985 A1 CL2009000985 A1 CL 2009000985A1 CL 2009000985 A CL2009000985 A CL 2009000985A CL 2009000985 A CL2009000985 A CL 2009000985A CL 2009000985 A1 CL2009000985 A1 CL 2009000985A1
Authority
CL
Chile
Prior art keywords
galactomannan
borate
diol
cis
lubricate
Prior art date
Application number
CL2009000985A
Other languages
English (en)
Spanish (es)
Inventor
Howard Allen Ketelson
James W Davis
David L Meadows
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40886688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009000985(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of CL2009000985A1 publication Critical patent/CL2009000985A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/08Ethers or acetals acyclic, e.g. paraformaldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2009000985A 2008-04-26 2009-04-24 Composicion oftalmica que comprende entre 0,16 y 0,19% p/v de un galactomanano, alrededor de 0,7% p/v de un borato, cis-diol y menos de 5 ppm de concentracion de cationes divalentes; y su uso para lubricar el ojo. CL2009000985A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4817508P 2008-04-26 2008-04-26

Publications (1)

Publication Number Publication Date
CL2009000985A1 true CL2009000985A1 (es) 2010-01-15

Family

ID=40886688

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009000985A CL2009000985A1 (es) 2008-04-26 2009-04-24 Composicion oftalmica que comprende entre 0,16 y 0,19% p/v de un galactomanano, alrededor de 0,7% p/v de un borato, cis-diol y menos de 5 ppm de concentracion de cationes divalentes; y su uso para lubricar el ojo.

Country Status (17)

Country Link
US (3) US20090270345A1 (ru)
EP (1) EP2278954B1 (ru)
JP (1) JP5659149B2 (ru)
KR (1) KR101592872B1 (ru)
CN (1) CN102046150B (ru)
AR (2) AR071834A1 (ru)
AU (1) AU2009240488B2 (ru)
BR (1) BRPI0910717A2 (ru)
CA (1) CA2722508C (ru)
CL (1) CL2009000985A1 (ru)
ES (1) ES2818619T3 (ru)
MX (1) MX2010011736A (ru)
NZ (1) NZ589323A (ru)
TW (1) TWI526213B (ru)
UY (1) UY31785A1 (ru)
WO (1) WO2009132294A1 (ru)
ZA (1) ZA201007644B (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US20050137166A1 (en) * 2003-12-19 2005-06-23 Alcon, Inc. Use of cooling agents to relieve mild ocular irritation and enhance comfort
JP5659149B2 (ja) * 2008-04-26 2015-01-28 アルコン リサーチ, リミテッド ポリマー性人工涙液系
TWI547522B (zh) 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
WO2011068872A2 (en) * 2009-12-03 2011-06-09 Alcon Research, Ltd. Carboxyvinyl polymer-containing nanoparticle suspension
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations
UA113434C2 (uk) * 2012-05-04 2017-01-25 Алкон Рісерч, Лтд. Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням
US20130344619A1 (en) 2012-06-21 2013-12-26 Lightship Medical Limited Glucose sensor
TW201938141A (zh) * 2018-02-21 2019-10-01 瑞士商諾華公司 基於脂質的眼用乳劑
US11730699B2 (en) 2018-02-21 2023-08-22 Alcon Inc. Lipid-based ophthalmic emulsion
JP6705495B1 (ja) * 2018-12-26 2020-06-03 株式会社Jvcケンウッド 車両用記録制御装置、車両用記録装置、車両用記録制御方法およびプログラム
TWI757773B (zh) * 2019-06-28 2022-03-11 瑞士商愛爾康公司 眼用組成物
BR112022002467A2 (pt) 2019-09-18 2022-07-19 Alcon Inc Insertos oculares de hidrogel suave embalados a úmido
CN114191378A (zh) * 2021-11-23 2022-03-18 温州医科大学附属眼视光医院 一种地夸磷索缓释凝胶及其制备方法与应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
GB1593954A (en) * 1977-01-31 1981-07-22 American Home Prod Xanthan gum or locust bean gum topical therapeutic compositions
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
ES2206965T3 (es) * 1997-07-29 2004-05-16 Alcon Laboratories, Inc. Composiciones oftalmicas que contienen polimeros de galactomanana y borato.
AU8570498A (en) * 1997-07-29 1999-02-22 Alcon Laboratories, Inc. Switchable viscoelastic systems containing galactomannan polymers and borate
IT1298758B1 (it) * 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
EP1696878A1 (en) * 2003-12-11 2006-09-06 Alcon, Inc. Ophthalmic compositions containing a polysaccharide/borate gelling system
DE102006031500A1 (de) 2006-07-06 2008-04-17 Henkel Kgaa O/W-Emulsion
WO2008036855A2 (en) * 2006-09-21 2008-03-27 Alcon Research, Ltd. Self-preserved aqueous pharmaceutical compositions
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
JP5659149B2 (ja) * 2008-04-26 2015-01-28 アルコン リサーチ, リミテッド ポリマー性人工涙液系
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations

Also Published As

Publication number Publication date
TW200948367A (en) 2009-12-01
KR101592872B1 (ko) 2016-02-12
TWI526213B (zh) 2016-03-21
NZ589323A (en) 2012-04-27
CA2722508C (en) 2016-08-16
US9259472B2 (en) 2016-02-16
US20090270345A1 (en) 2009-10-29
ZA201007644B (en) 2011-12-28
CA2722508A1 (en) 2009-10-29
AU2009240488A1 (en) 2009-10-29
KR20110007228A (ko) 2011-01-21
AR071834A1 (es) 2010-07-21
US8685945B2 (en) 2014-04-01
US20140161760A1 (en) 2014-06-12
JP2011518842A (ja) 2011-06-30
EP2278954B1 (en) 2020-08-26
CN102046150A (zh) 2011-05-04
EP2278954A1 (en) 2011-02-02
CN102046150B (zh) 2013-07-24
US20120070402A1 (en) 2012-03-22
AR112286A2 (es) 2019-10-09
MX2010011736A (es) 2011-01-21
WO2009132294A1 (en) 2009-10-29
JP5659149B2 (ja) 2015-01-28
ES2818619T3 (es) 2021-04-13
UY31785A1 (es) 2009-08-03
AU2009240488B2 (en) 2013-02-21
BRPI0910717A2 (pt) 2015-09-29

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