CL2008003823A1 - Composicion farmaceutica para administracion oral que comprende 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona o una sal y 2,5-12% de un lubricante definido; proceso de preparacion; util para tratar trastornos o enfermedades mediadas por linfocitos t y/o proteina quinasa c. - Google Patents
Composicion farmaceutica para administracion oral que comprende 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona o una sal y 2,5-12% de un lubricante definido; proceso de preparacion; util para tratar trastornos o enfermedades mediadas por linfocitos t y/o proteina quinasa c.Info
- Publication number
- CL2008003823A1 CL2008003823A1 CL2008003823A CL2008003823A CL2008003823A1 CL 2008003823 A1 CL2008003823 A1 CL 2008003823A1 CL 2008003823 A CL2008003823 A CL 2008003823A CL 2008003823 A CL2008003823 A CL 2008003823A CL 2008003823 A1 CL2008003823 A1 CL 2008003823A1
- Authority
- CL
- Chile
- Prior art keywords
- quinazolin
- piperazin
- indol
- dione
- pyrrole
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Physical Education & Sports Medicine (AREA)
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- Vascular Medicine (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
Abstract
Composición farmacéutica sólida para administración oral en forma de tableta que comprende 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona y al menos 2 al 15% en peso de un lubricante, siendo el peso total de la composición, el peso total del núcleo de la tableta; procedimiento de preparación.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07150347 | 2007-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003823A1 true CL2008003823A1 (es) | 2010-01-22 |
Family
ID=39495348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003823A CL2008003823A1 (es) | 2007-12-21 | 2008-12-19 | Composicion farmaceutica para administracion oral que comprende 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona o una sal y 2,5-12% de un lubricante definido; proceso de preparacion; util para tratar trastornos o enfermedades mediadas por linfocitos t y/o proteina quinasa c. |
Country Status (21)
Country | Link |
---|---|
US (1) | US20100316713A1 (es) |
EP (1) | EP2240164A2 (es) |
JP (2) | JP5525453B2 (es) |
KR (1) | KR20100103625A (es) |
CN (1) | CN101883558A (es) |
AR (1) | AR069799A1 (es) |
AU (1) | AU2008340019B2 (es) |
BR (1) | BRPI0820839A2 (es) |
CA (1) | CA2709909A1 (es) |
CL (1) | CL2008003823A1 (es) |
CO (1) | CO6382170A2 (es) |
EC (1) | ECSP10010360A (es) |
IL (1) | IL205931A0 (es) |
MA (1) | MA31950B1 (es) |
MY (1) | MY158293A (es) |
NZ (1) | NZ586313A (es) |
PE (1) | PE20091522A1 (es) |
RU (1) | RU2485951C2 (es) |
TN (1) | TN2010000243A1 (es) |
TW (1) | TWI449541B (es) |
WO (1) | WO2009080762A2 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR069799A1 (es) * | 2007-12-21 | 2010-02-17 | Novartis Ag | Composicion farmaceutica |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ323571A (en) * | 1995-11-20 | 1998-12-23 | Lilly Co Eli | Protein kinase c inhibitor |
TW200918046A (en) * | 2002-04-03 | 2009-05-01 | Novartis Ag | Indolylmaleimide derivatives |
GB0504203D0 (en) * | 2005-03-01 | 2005-04-06 | Novartis Ag | Organic compounds |
AU2006252553B2 (en) * | 2005-06-02 | 2012-03-29 | Merck Sharp & Dohme Corp. | Combination of HCV protease inhibitors with a surfactant |
BRPI0613611A2 (pt) * | 2005-07-22 | 2011-01-18 | Myriad Genetics Inc | formulações de alta concentração de fármaco e formas de dosagens |
US7762932B2 (en) * | 2007-09-17 | 2010-07-27 | Fitness Anywhere, Inc. | Inelastic exercise device having a limited range |
AR069799A1 (es) * | 2007-12-21 | 2010-02-17 | Novartis Ag | Composicion farmaceutica |
-
2008
- 2008-12-18 AR ARP080105520A patent/AR069799A1/es unknown
- 2008-12-18 PE PE2008002124A patent/PE20091522A1/es not_active Application Discontinuation
- 2008-12-19 RU RU2010129544/15A patent/RU2485951C2/ru not_active IP Right Cessation
- 2008-12-19 CA CA2709909A patent/CA2709909A1/en not_active Abandoned
- 2008-12-19 MY MYPI2010002374A patent/MY158293A/en unknown
- 2008-12-19 EP EP08865096A patent/EP2240164A2/en not_active Withdrawn
- 2008-12-19 CL CL2008003823A patent/CL2008003823A1/es unknown
- 2008-12-19 BR BRPI0820839-5A patent/BRPI0820839A2/pt not_active IP Right Cessation
- 2008-12-19 KR KR1020107016148A patent/KR20100103625A/ko not_active Application Discontinuation
- 2008-12-19 US US12/808,905 patent/US20100316713A1/en not_active Abandoned
- 2008-12-19 WO PCT/EP2008/068051 patent/WO2009080762A2/en active Application Filing
- 2008-12-19 NZ NZ586313A patent/NZ586313A/xx not_active IP Right Cessation
- 2008-12-19 CN CN2008801190561A patent/CN101883558A/zh active Pending
- 2008-12-19 AU AU2008340019A patent/AU2008340019B2/en not_active Ceased
- 2008-12-19 TW TW097149851A patent/TWI449541B/zh not_active IP Right Cessation
- 2008-12-19 JP JP2010538767A patent/JP5525453B2/ja not_active Expired - Fee Related
-
2010
- 2010-05-24 IL IL205931A patent/IL205931A0/en unknown
- 2010-05-28 TN TN2010000243A patent/TN2010000243A1/fr unknown
- 2010-06-29 MA MA32969A patent/MA31950B1/fr unknown
- 2010-07-20 EC EC2010010360A patent/ECSP10010360A/es unknown
- 2010-07-21 CO CO10088697A patent/CO6382170A2/es not_active Application Discontinuation
-
2013
- 2013-11-15 JP JP2013236787A patent/JP2014040477A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL205931A0 (en) | 2010-11-30 |
WO2009080762A3 (en) | 2009-09-11 |
JP5525453B2 (ja) | 2014-06-18 |
US20100316713A1 (en) | 2010-12-16 |
RU2485951C2 (ru) | 2013-06-27 |
CO6382170A2 (es) | 2012-02-15 |
AU2008340019B2 (en) | 2012-05-03 |
RU2010129544A (ru) | 2012-01-27 |
PE20091522A1 (es) | 2009-10-29 |
TW200940106A (en) | 2009-10-01 |
NZ586313A (en) | 2012-08-31 |
MA31950B1 (fr) | 2010-12-01 |
CA2709909A1 (en) | 2009-07-02 |
TWI449541B (zh) | 2014-08-21 |
JP2014040477A (ja) | 2014-03-06 |
WO2009080762A2 (en) | 2009-07-02 |
CN101883558A (zh) | 2010-11-10 |
JP2011506576A (ja) | 2011-03-03 |
EP2240164A2 (en) | 2010-10-20 |
AR069799A1 (es) | 2010-02-17 |
TN2010000243A1 (en) | 2011-11-11 |
KR20100103625A (ko) | 2010-09-27 |
ECSP10010360A (es) | 2010-08-31 |
BRPI0820839A2 (pt) | 2015-06-16 |
AU2008340019A1 (en) | 2009-07-02 |
MY158293A (en) | 2016-09-30 |
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