CL2008000901A1 - Procedimiento para preparar un derivado de epotilona, usando piridinas sustituidas y metiltrioxorenio como catalizador; y un derivado de epotilona que contiene renio. - Google Patents

Procedimiento para preparar un derivado de epotilona, usando piridinas sustituidas y metiltrioxorenio como catalizador; y un derivado de epotilona que contiene renio.

Info

Publication number
CL2008000901A1
CL2008000901A1 CL200800901A CL2008000901A CL2008000901A1 CL 2008000901 A1 CL2008000901 A1 CL 2008000901A1 CL 200800901 A CL200800901 A CL 200800901A CL 2008000901 A CL2008000901 A CL 2008000901A CL 2008000901 A1 CL2008000901 A1 CL 2008000901A1
Authority
CL
Chile
Prior art keywords
epotilone
derivative
methyltrioxorene
renio
pyridins
Prior art date
Application number
CL200800901A
Other languages
English (en)
Spanish (es)
Inventor
Johannes Platzek Dr Orlin P Dr
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of CL2008000901A1 publication Critical patent/CL2008000901A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CL200800901A 2007-03-30 2008-03-28 Procedimiento para preparar un derivado de epotilona, usando piridinas sustituidas y metiltrioxorenio como catalizador; y un derivado de epotilona que contiene renio. CL2008000901A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007016046A DE102007016046A1 (de) 2007-03-30 2007-03-30 Verfahren zur Herstellung von Epothilonderivaten durch selektive katalytische Epoxidierung

Publications (1)

Publication Number Publication Date
CL2008000901A1 true CL2008000901A1 (es) 2008-10-17

Family

ID=39551678

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200800901A CL2008000901A1 (es) 2007-03-30 2008-03-28 Procedimiento para preparar un derivado de epotilona, usando piridinas sustituidas y metiltrioxorenio como catalizador; y un derivado de epotilona que contiene renio.

Country Status (13)

Country Link
US (2) US20080242868A1 (enExample)
EP (1) EP2142539A2 (enExample)
JP (1) JP2010523481A (enExample)
KR (1) KR20090125259A (enExample)
CN (1) CN101652362B (enExample)
AR (1) AR066692A1 (enExample)
CA (1) CA2681806A1 (enExample)
CL (1) CL2008000901A1 (enExample)
DE (1) DE102007016046A1 (enExample)
PA (1) PA8773901A1 (enExample)
TW (1) TW200902538A (enExample)
UY (1) UY30985A1 (enExample)
WO (1) WO2008119563A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114539143A (zh) * 2022-01-28 2022-05-27 安徽瑞邦生物科技有限公司 一种4-氰基吡啶的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69910831T2 (de) * 1998-12-22 2004-07-15 Novartis Ag Epothilonderivate und ihre verwendung als antitumormittel
PE20010116A1 (es) 1999-04-30 2001-02-15 Schering Ag Derivados de 6-alquenil-, 6-alquinil- y 6-epoxi-epotilona, procedimientos para su preparacion
EP1340498A1 (en) * 2002-03-01 2003-09-03 Schering Aktiengesellschaft Use of epothilones in the treatment of brain diseases associated with proliferative processes
GB0405898D0 (en) * 2004-03-16 2004-04-21 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
KR20090125259A (ko) 2009-12-04
AR066692A1 (es) 2009-09-09
US20120077984A1 (en) 2012-03-29
US20080242868A1 (en) 2008-10-02
CA2681806A1 (en) 2008-10-09
US8314248B2 (en) 2012-11-20
JP2010523481A (ja) 2010-07-15
PA8773901A1 (es) 2008-11-19
CN101652362A (zh) 2010-02-17
CN101652362B (zh) 2012-10-10
DE102007016046A1 (de) 2008-10-23
TW200902538A (en) 2009-01-16
WO2008119563A3 (de) 2009-02-12
WO2008119563A2 (de) 2008-10-09
UY30985A1 (es) 2008-10-31
EP2142539A2 (de) 2010-01-13

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