CL2008000613A1 - Uso del acido (s,s)-(1-aminometil-3,4-dimetil-ciclopentil)-acetico para preparar un medicamento util para tratar tinnitis en un mamifero. - Google Patents
Uso del acido (s,s)-(1-aminometil-3,4-dimetil-ciclopentil)-acetico para preparar un medicamento util para tratar tinnitis en un mamifero.Info
- Publication number
- CL2008000613A1 CL2008000613A1 CL2008000613A CL2008000613A CL2008000613A1 CL 2008000613 A1 CL2008000613 A1 CL 2008000613A1 CL 2008000613 A CL2008000613 A CL 2008000613A CL 2008000613 A CL2008000613 A CL 2008000613A CL 2008000613 A1 CL2008000613 A1 CL 2008000613A1
- Authority
- CL
- Chile
- Prior art keywords
- acid
- aminomethyl
- cyclopentyl
- mammal
- dimethyl
- Prior art date
Links
- -1 (s, s) - (1-aminomethyl-3,4-dimethyl-cyclopentyl) Chemical group 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000009205 Tinnitus Diseases 0.000 abstract 1
- 231100000886 tinnitus Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35363202P | 2002-01-31 | 2002-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2008000613A1 true CL2008000613A1 (es) | 2008-11-07 |
Family
ID=27663234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2008000613A CL2008000613A1 (es) | 2002-01-31 | 2008-02-28 | Uso del acido (s,s)-(1-aminometil-3,4-dimetil-ciclopentil)-acetico para preparar un medicamento util para tratar tinnitis en un mamifero. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7026505B2 (https=) |
| EP (1) | EP1469841A1 (https=) |
| JP (1) | JP2005521664A (https=) |
| KR (1) | KR20040081478A (https=) |
| CN (1) | CN1625393A (https=) |
| AU (1) | AU2003201716B2 (https=) |
| BR (1) | BR0307411A (https=) |
| CA (1) | CA2474000A1 (https=) |
| CL (1) | CL2008000613A1 (https=) |
| IL (1) | IL162028A0 (https=) |
| MX (1) | MXPA04004105A (https=) |
| NZ (1) | NZ532624A (https=) |
| PL (1) | PL371944A1 (https=) |
| TW (1) | TW200306177A (https=) |
| WO (1) | WO2003063845A1 (https=) |
| ZA (1) | ZA200403069B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL189872B1 (pl) | 1996-07-24 | 2005-10-31 | Warner Lambert Co | Zastosowanie izobutylogaby i jej pochodnych do wytwarzania leku do leczenia bólu |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| BRPI0408110A (pt) | 2003-03-07 | 2006-03-01 | Warner Lambert Co | derivados de beta-aminoácido substituìdos com tetrazol e oxadiazolona |
| EP1622569B1 (en) | 2003-04-24 | 2015-12-02 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metallproteases |
| EP1622613A4 (en) * | 2003-05-14 | 2008-04-02 | Cytokinetics Inc | COMPOUNDS, COMPOSITIONS AND METHODS |
| CN101506140B (zh) * | 2006-08-24 | 2014-06-18 | 百时美施贵宝公司 | 环状11β-羟类固醇脱氢酶Ⅰ型抑制剂 |
| US7727978B2 (en) | 2006-08-24 | 2010-06-01 | Bristol-Myers Squibb Company | Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| EA200970483A1 (ru) * | 2006-11-14 | 2009-12-30 | Ксенопорт, Инк. | Применение пролекарств габапентина и прегабалина для лечения шума в ушах |
| US20080161393A1 (en) * | 2006-12-08 | 2008-07-03 | Barrett Ronald W | Use of prodrugs of GABA analogs for treating disease |
| ITMI20071492A1 (it) | 2007-07-24 | 2009-01-25 | S I I T Srl Servizio Internazi | "composizioni per il trattamento e la prevenzione di condizioni di vertigine e acufeni comprendenti citicolina, estratto di ginkgo biloba e flavoni dimerici di ginkgo biloba" |
| US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| CN101260063B (zh) * | 2008-03-21 | 2013-06-19 | 北京润德康医药技术有限公司 | γ-氨基丁酸衍生物及其制备方法 |
| SG157299A1 (en) | 2008-05-09 | 2009-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
| CN111718379A (zh) * | 2019-03-19 | 2020-09-29 | 海南长安国际制药有限公司 | 具有l1和l2结构的铂类物质及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| US6197819B1 (en) * | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
| WO1998017627A1 (en) * | 1996-10-23 | 1998-04-30 | Warner-Lambert Company | Substituted gamma aminobutyric acids as pharmaceutical agents |
| US6518289B1 (en) * | 1997-12-16 | 2003-02-11 | Pfizer, Inc. | 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
| NZ503980A (en) * | 1997-12-16 | 2002-09-27 | Warner Lambert Co | 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (= gabapentin analogues), pharmaceuticals thereof, and their use in the treatment of neurological disorders |
| DK1045839T3 (da) * | 1997-12-16 | 2004-07-05 | Warner Lambert Co | Hidtil ukendte aminer som farmaceutiske midler |
| EP1082306A1 (en) * | 1998-05-26 | 2001-03-14 | Warner-Lambert Company | Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel |
| GB9821179D0 (en) * | 1998-09-30 | 1998-11-25 | Merck Sharp & Dohme | Therapeutic use |
| RS50352B (sr) * | 1999-06-10 | 2009-11-10 | Warner-Lambert Company Llc., | Monosupstituisane 3-propil gama-aminobuterne kiseline |
| HN2000000224A (es) * | 1999-10-20 | 2001-04-11 | Warner Lambert Co | Aminoacidos biciclicos como agentes farmaceuticos |
| US6620829B2 (en) * | 2000-10-17 | 2003-09-16 | Warner-Lambert Company | Method of treating noninflammatory cartilage damage |
-
2003
- 2003-01-20 CN CNA038031388A patent/CN1625393A/zh active Pending
- 2003-01-20 KR KR10-2004-7011809A patent/KR20040081478A/ko not_active Ceased
- 2003-01-20 MX MXPA04004105A patent/MXPA04004105A/es active IP Right Grant
- 2003-01-20 BR BR0307411-0A patent/BR0307411A/pt not_active IP Right Cessation
- 2003-01-20 AU AU2003201716A patent/AU2003201716B2/en not_active Ceased
- 2003-01-20 WO PCT/IB2003/000232 patent/WO2003063845A1/en not_active Ceased
- 2003-01-20 NZ NZ532624A patent/NZ532624A/en unknown
- 2003-01-20 EP EP03700417A patent/EP1469841A1/en not_active Ceased
- 2003-01-20 JP JP2003563539A patent/JP2005521664A/ja not_active Withdrawn
- 2003-01-20 PL PL03371944A patent/PL371944A1/xx not_active Application Discontinuation
- 2003-01-20 CA CA002474000A patent/CA2474000A1/en not_active Abandoned
- 2003-01-20 IL IL16202803A patent/IL162028A0/xx unknown
- 2003-01-29 US US10/353,367 patent/US7026505B2/en not_active Expired - Fee Related
- 2003-01-30 TW TW092102235A patent/TW200306177A/zh unknown
-
2004
- 2004-04-22 ZA ZA200403069A patent/ZA200403069B/en unknown
-
2005
- 2005-12-21 US US11/314,126 patent/US7138542B2/en not_active Expired - Fee Related
-
2008
- 2008-02-28 CL CL2008000613A patent/CL2008000613A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ532624A (en) | 2007-05-31 |
| US20060100281A1 (en) | 2006-05-11 |
| AU2003201716B2 (en) | 2008-04-17 |
| IL162028A0 (en) | 2005-11-20 |
| TW200306177A (en) | 2003-11-16 |
| WO2003063845A1 (en) | 2003-08-07 |
| US7138542B2 (en) | 2006-11-21 |
| US20030176504A1 (en) | 2003-09-18 |
| MXPA04004105A (es) | 2004-11-29 |
| KR20040081478A (ko) | 2004-09-21 |
| CN1625393A (zh) | 2005-06-08 |
| EP1469841A1 (en) | 2004-10-27 |
| JP2005521664A (ja) | 2005-07-21 |
| CA2474000A1 (en) | 2003-08-07 |
| PL371944A1 (en) | 2005-07-11 |
| ZA200403069B (en) | 2005-04-22 |
| US7026505B2 (en) | 2006-04-11 |
| BR0307411A (pt) | 2004-12-07 |
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