CL2007003221A1 - Metodo para producir un polipeptido en un cultivo celular; polipeptido producido por dicho cultivo celular; composicion farmaceutica que comprende dicho polipeptido; y un medio de cultivo celular. - Google Patents

Metodo para producir un polipeptido en un cultivo celular; polipeptido producido por dicho cultivo celular; composicion farmaceutica que comprende dicho polipeptido; y un medio de cultivo celular.

Info

Publication number
CL2007003221A1
CL2007003221A1 CL200703221A CL2007003221A CL2007003221A1 CL 2007003221 A1 CL2007003221 A1 CL 2007003221A1 CL 200703221 A CL200703221 A CL 200703221A CL 2007003221 A CL2007003221 A CL 2007003221A CL 2007003221 A1 CL2007003221 A1 CL 2007003221A1
Authority
CL
Chile
Prior art keywords
polypeptide
cell culture
culture
producing
pharmaceutical composition
Prior art date
Application number
CL200703221A
Other languages
English (en)
Inventor
Yen-Tung Wang Wenge Nolan Luan
Original Assignee
Wyeth6 3
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39430451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2007003221(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth6 3 filed Critical Wyeth6 3
Publication of CL2007003221A1 publication Critical patent/CL2007003221A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL200703221A 2006-11-08 2007-11-08 Metodo para producir un polipeptido en un cultivo celular; polipeptido producido por dicho cultivo celular; composicion farmaceutica que comprende dicho polipeptido; y un medio de cultivo celular. CL2007003221A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85828906P 2006-11-08 2006-11-08

Publications (1)

Publication Number Publication Date
CL2007003221A1 true CL2007003221A1 (es) 2008-05-16

Family

ID=39430451

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200703221A CL2007003221A1 (es) 2006-11-08 2007-11-08 Metodo para producir un polipeptido en un cultivo celular; polipeptido producido por dicho cultivo celular; composicion farmaceutica que comprende dicho polipeptido; y un medio de cultivo celular.

Country Status (26)

Country Link
US (2) US8232075B2 (es)
EP (2) EP2078071B1 (es)
JP (2) JP5564259B2 (es)
KR (1) KR101523782B1 (es)
CN (2) CN101535469A (es)
AR (1) AR063623A1 (es)
AU (1) AU2007323978B2 (es)
BR (1) BRPI0718713B1 (es)
CA (1) CA2668771C (es)
CL (1) CL2007003221A1 (es)
CR (1) CR10781A (es)
DK (1) DK2078071T3 (es)
EC (1) ECSP099313A (es)
ES (1) ES2538986T3 (es)
HK (1) HK1132300A1 (es)
IL (1) IL198486A (es)
MX (1) MX2009004974A (es)
NO (1) NO20091607L (es)
PE (1) PE20081655A1 (es)
PL (1) PL2078071T3 (es)
PT (1) PT2078071E (es)
RU (1) RU2520810C2 (es)
SI (1) SI2078071T1 (es)
TW (1) TW200827445A (es)
WO (1) WO2008063892A2 (es)
ZA (1) ZA200903170B (es)

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TWI601823B (zh) 2007-04-26 2017-10-11 Chugai Pharmaceutical Co Ltd Cell culture methods using media containing high concentrations of amino acids
WO2009023562A2 (en) 2007-08-09 2009-02-19 Wyeth Use of perfusion to enhance production of fed-batch cell culture in bioreactors
US8178318B2 (en) * 2008-08-06 2012-05-15 Praxair Technology, Inc. Method for controlling pH, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield
WO2010017337A1 (en) * 2008-08-06 2010-02-11 Praxair Technology, Inc. System and method for controlling a mammalian cell culture process
CN102712691A (zh) 2009-08-06 2012-10-03 弗·哈夫曼-拉罗切有限公司 蛋白质纯化中提高病毒去除的方法
US20110262965A1 (en) * 2010-04-23 2011-10-27 Life Technologies Corporation Cell culture medium comprising small peptides
RU2577972C2 (ru) 2010-04-26 2016-03-20 Новартис Аг Способ получения рекомбинантного полипептида
SG185038A1 (en) * 2010-04-26 2012-11-29 Novartis Ag Improved cell culture medium
ES2434737T3 (es) * 2010-10-27 2013-12-17 Lonza Biologics Plc. Procedimiento rápido de selección de células (líneas celulares) dirigida
PT105484A (pt) 2011-01-14 2012-07-16 Univ Nova De Lisboa Um método de ambientómica funcional para engenharia de meio de cultura celular
WO2013006479A2 (en) 2011-07-01 2013-01-10 Amgen Inc. Mammalian cell culture
CN103717729B (zh) 2011-07-08 2017-11-21 动量制药公司 细胞培养方法
EP3395423B1 (en) * 2013-03-14 2023-09-20 Amgen Inc. Removal of leaked affinity purification ligand
AR095196A1 (es) * 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
TW202340452A (zh) 2015-08-04 2023-10-16 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
BR112018008864A8 (pt) * 2015-11-17 2019-02-26 Pfizer meios e métodos de fermentação para a produção de polissacarídeos em uma cultura de células bacterianas
SG11201808356UA (en) * 2016-04-05 2018-10-30 Pfizer Cell culture process
CN106096077B (zh) * 2016-05-26 2019-05-21 新乡医学院 培养基优化方法
JP6314201B1 (ja) * 2016-11-21 2018-04-18 テラファーマ株式会社 樹状細胞洗浄液及びこれを用いた樹状細胞の洗浄方法、並びに樹状細胞含有組成物の調製方法
CA3052539C (en) * 2017-02-08 2022-08-30 Pfizer Inc. Large scale production process for capped and un-capped antibody cysteines and their use in therapeutic protein conjugation
GB201708655D0 (en) * 2017-05-31 2017-07-12 Ucb Biopharma Sprl Cell culture methods
BR112020003122A2 (pt) * 2017-10-16 2020-08-04 Regeneron Pharmaceuticals, Inc. métodos e sistemas para controlar condições de meio de cultura celular e para reduzir modificações pós-translação de uma proteína secretada
US20210171901A1 (en) * 2017-11-16 2021-06-10 Life Technologies Corporation Streamlined methods for making liquid media
JP6385607B2 (ja) * 2018-02-13 2018-09-05 テラファーマ株式会社 樹状細胞ワクチン
CN108823173A (zh) * 2018-07-24 2018-11-16 郑州伊美诺生物技术有限公司 用于杂交瘤细胞培养的补料培养基及其制备方法
CN109576203B (zh) * 2018-12-20 2021-03-23 吉林省浦生泰生物技术有限责任公司 一种基于中药添加剂的复合益生菌培养基及其制备方法
CN111748527B (zh) * 2020-05-15 2021-01-29 上海多宁生物科技有限公司 化学成分限定高效补料培养基及其制备方法和应用
CN113450882B (zh) * 2020-09-27 2022-03-01 深圳太力生物技术有限责任公司 一种基于人工智能的基础培养基配方开发方法及系统
JP2022060169A (ja) 2020-10-02 2022-04-14 ファイザー・インク Ｒｓｖ ｆタンパク質生産のための細胞培養工程
WO2022254319A1 (en) 2021-06-01 2022-12-08 Pfizer Inc. Cell culture method for producing sfgfr3 polypeptide

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US5122469A (en) * 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
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USH1532H (en) 1993-11-03 1996-05-07 Genetics Institute, Inc. Adaption of mammalian cell lines to high cell densities
US5399677A (en) * 1993-12-07 1995-03-21 Genetics Institute, Inc. Mutants of bone morphogenetic proteins
US5856179A (en) 1994-03-10 1999-01-05 Genentech, Inc. Polypeptide production in animal cell culture
RU2141531C1 (ru) * 1999-05-26 1999-11-20 Российское акционерное общество открытого типа "Биопрепарат" Способ получения рекомбинантного инсулина человека
CA2388245C (en) 1999-10-19 2012-01-10 Tatsuya Ogawa The use of serum-free adapted rat cells for producing heterologous polypeptides
PT1623019E (pt) * 2003-05-15 2010-07-20 Wyeth Llc ALIMENTAÆO COM GLUCOSE DE MODO LIMITADO PARA CULTURA DE CéLULAS ANIMAIS
CA2542121A1 (en) 2003-10-09 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. Genomically modified cell neutralized to serum-free system
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TW200827445A (en) * 2006-11-08 2008-07-01 Wyeth Corp Rationally designed media for cell culture

Also Published As

Publication number Publication date
EP2078071B1 (en) 2015-03-18
CR10781A (es) 2009-06-09
DK2078071T3 (en) 2015-04-20
BRPI0718713B1 (pt) 2019-12-24
CN101535469A (zh) 2009-09-16
NO20091607L (no) 2009-05-28
RU2520810C2 (ru) 2014-06-27
ES2538986T3 (es) 2015-06-25
KR101523782B1 (ko) 2015-05-28
CA2668771A1 (en) 2008-05-29
HK1132300A1 (en) 2010-02-19
WO2008063892A2 (en) 2008-05-29
MX2009004974A (es) 2009-05-20
JP2010508853A (ja) 2010-03-25
PT2078071E (pt) 2015-07-16
IL198486A0 (en) 2011-08-01
EP2921552A1 (en) 2015-09-23
ECSP099313A (es) 2009-06-30
SI2078071T1 (sl) 2015-05-29
KR20090079254A (ko) 2009-07-21
AR063623A1 (es) 2009-02-04
IL198486A (en) 2015-06-30
ZA200903170B (en) 2010-03-31
TW200827445A (en) 2008-07-01
US20130084593A1 (en) 2013-04-04
US8232075B2 (en) 2012-07-31
EP2078071A2 (en) 2009-07-15
WO2008063892A3 (en) 2008-08-28
US20080108553A1 (en) 2008-05-08
RU2009114855A (ru) 2010-12-20
CN104152395B (zh) 2020-03-10
JP5564259B2 (ja) 2014-07-30
JP2014128276A (ja) 2014-07-10
CN104152395A (zh) 2014-11-19
BRPI0718713A2 (pt) 2013-11-26
CA2668771C (en) 2016-03-15
PL2078071T3 (pl) 2015-07-31
PE20081655A1 (es) 2008-12-03
AU2007323978B2 (en) 2012-08-16
AU2007323978A1 (en) 2008-05-29

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