CL2000002938A1 - Cristales del acido (e)-4-[4-(5-metil-2-fenil-4-oxazolilmetoxi)benciloxiimino]-4-fenilbutirico, composicion farmaceutica que los comprende y su uso en el tratamiento o prevencion de la diabetes mellitus, hiperlipemia, disminucion en la tolerancia a la glucosa, enfermedades inflamatorias, arteriosclerosis. - Google Patents

Cristales del acido (e)-4-[4-(5-metil-2-fenil-4-oxazolilmetoxi)benciloxiimino]-4-fenilbutirico, composicion farmaceutica que los comprende y su uso en el tratamiento o prevencion de la diabetes mellitus, hiperlipemia, disminucion en la tolerancia a la glucosa, enfermedades inflamatorias, arteriosclerosis.

Info

Publication number
CL2000002938A1
CL2000002938A1 CL2000002938A CL2000002938A CL2000002938A1 CL 2000002938 A1 CL2000002938 A1 CL 2000002938A1 CL 2000002938 A CL2000002938 A CL 2000002938A CL 2000002938 A CL2000002938 A CL 2000002938A CL 2000002938 A1 CL2000002938 A1 CL 2000002938A1
Authority
CL
Chile
Prior art keywords
crystals
phenyl
methyl
oxazolylmethoxy
benzyloxyimino
Prior art date
Application number
CL2000002938A
Other languages
English (en)
Inventor
Yu Y Imoto Hiroshi Momose
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of CL2000002938A1 publication Critical patent/CL2000002938A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

CRISTALES DE ACIDO (E)-4-(5-METIL-2-FENIL-4- OXAZOLILMETOXI)BENZILOXIIMINO)-4-FENILBUTIRICO (CON LA CONDICION DE QUE LOS CRISTALES CUYO PUNTO DE FUSION FLUCTUA ENTRE 126 GRADOS C. Y 127 GRADOS C. QUEDEN EXCLUIDOS), LOS CUALES TIENEN UNA EXCELENTE ACCION CONTRA LA DIABETES.
CL2000002938A 1999-10-29 2000-10-26 Cristales del acido (e)-4-[4-(5-metil-2-fenil-4-oxazolilmetoxi)benciloxiimino]-4-fenilbutirico, composicion farmaceutica que los comprende y su uso en el tratamiento o prevencion de la diabetes mellitus, hiperlipemia, disminucion en la tolerancia a la glucosa, enfermedades inflamatorias, arteriosclerosis. CL2000002938A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30834699 1999-10-29

Publications (1)

Publication Number Publication Date
CL2000002938A1 true CL2000002938A1 (es) 2009-05-15

Family

ID=17979966

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2000002938A CL2000002938A1 (es) 1999-10-29 2000-10-26 Cristales del acido (e)-4-[4-(5-metil-2-fenil-4-oxazolilmetoxi)benciloxiimino]-4-fenilbutirico, composicion farmaceutica que los comprende y su uso en el tratamiento o prevencion de la diabetes mellitus, hiperlipemia, disminucion en la tolerancia a la glucosa, enfermedades inflamatorias, arteriosclerosis.

Country Status (19)

Country Link
US (1) US6777435B1 (es)
EP (1) EP1224178B1 (es)
KR (1) KR100433885B1 (es)
CN (1) CN1407975A (es)
AR (1) AR031078A1 (es)
AT (1) ATE243684T1 (es)
AU (1) AU7958100A (es)
CA (1) CA2388200A1 (es)
CL (1) CL2000002938A1 (es)
CO (1) CO5261530A1 (es)
DE (1) DE60003577T2 (es)
HK (1) HK1044536A1 (es)
HU (1) HUP0203884A3 (es)
MY (1) MY135840A (es)
NO (1) NO20022007L (es)
PE (1) PE20010761A1 (es)
PL (1) PL364171A1 (es)
TW (1) TW558554B (es)
WO (1) WO2001032637A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030134884A1 (en) * 2000-03-28 2003-07-17 Masatoshi Hazama Neovascularization inhibitors
CA2442917C (en) 2001-04-04 2011-02-01 Ortho-Mcneil Pharmaceutical, Inc. Combination therapy comprising glucose reabsorption inhibitors and ppar modulators
CN100384430C (zh) * 2001-04-04 2008-04-30 奥索-麦克尼尔药品公司 含有葡萄糖重吸收抑制剂和维生素a类-x受体调节剂的联合治疗
EP1400529A4 (en) 2001-05-30 2007-12-19 Kissei Pharmaceutical GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL AND INTERMEDIARY USE THEREOF
TWI327462B (en) * 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
AU2003242396A1 (en) * 2002-05-24 2003-12-12 Takeda Pharmaceutical Company Limited Insulin resistance improving agents
US7888346B2 (en) * 2004-09-24 2011-02-15 Universtiy of Maryland, Baltimore Method of treating organophosphorous poisoning
US9132135B2 (en) * 2004-09-24 2015-09-15 University Of Maryland, Baltimore Method of treating organophosphorous poisoning
EP1937297A2 (en) * 2005-09-08 2008-07-02 Gastrotech Pharma A/S Use of a glp-1 molecule for treatment of biliary dyskinesia and/or biliary pain/discomfort
TW201138843A (en) 2009-12-18 2011-11-16 Colgate Palmolive Co Biguanide preservation of precipitated calcium carbonate
CN106211757B (zh) * 2014-01-17 2022-06-07 康奈尔大学 使用维甲酸受体激动剂治疗代谢综合征相关病况的方法
US11191755B2 (en) 2014-01-17 2021-12-07 Cornell University Compositions and methods for providing cardioprotective effects
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
KR102281228B1 (ko) 2019-09-03 2021-07-22 신창수 과수나무의 가지지지용 파이프클램프

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU766831B2 (en) * 1998-05-11 2003-10-23 Takeda Pharmaceutical Company Limited Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity
WO2001032608A1 (fr) * 1999-10-29 2001-05-10 Takeda Chemical Industries, Ltd. Procédé de préparation de dérivés d'acide oxyminoalcanoïque

Also Published As

Publication number Publication date
KR20010102429A (ko) 2001-11-15
CO5261530A1 (es) 2003-03-31
KR100433885B1 (ko) 2004-06-04
DE60003577D1 (de) 2003-07-31
MY135840A (en) 2008-07-31
EP1224178B1 (en) 2003-06-25
US6777435B1 (en) 2004-08-17
WO2001032637A1 (en) 2001-05-10
AU7958100A (en) 2001-05-14
CA2388200A1 (en) 2001-05-21
NO20022007L (no) 2002-06-24
EP1224178A1 (en) 2002-07-24
TW558554B (en) 2003-10-21
ATE243684T1 (de) 2003-07-15
PE20010761A1 (es) 2001-08-01
PL364171A1 (en) 2004-12-13
DE60003577T2 (de) 2004-04-29
HUP0203884A3 (en) 2005-01-28
AR031078A1 (es) 2003-09-10
HK1044536A1 (en) 2002-10-25
NO20022007D0 (no) 2002-04-26
HUP0203884A2 (hu) 2003-03-28
CN1407975A (zh) 2003-04-02

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